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  1. AU="García-Cenador, M B"
  2. AU="Youssef B. Fawaz"
  3. AU="Mohamed, Dina Mahmoud"
  4. AU="Asante-Addo, Collins"
  5. AU="Belluti, Federica"
  6. AU="Sebastian Fetscher"
  7. AU="Reshef, Yakir A"
  8. AU="Gerstenberger, John"
  9. AU="Bilbul, Melanie" AU="Bilbul, Melanie"
  10. AU="Martínez-Vernaza, Samuel"
  11. AU="Takenoya, Takashi"
  12. AU="Russell, Roslin"
  13. AU=Kim Ka Young
  14. AU="Mateja, Allyson"
  15. AU="Todorov, Alexander B."
  16. AU=Mosallanezhad Behzad
  17. AU=Rochman Yrina AU=Rochman Yrina
  18. AU="Wang, Hong-Bo"
  19. AU="Zhong, Boyu"
  20. AU=Gimeno-Costa Ricardo AU=Gimeno-Costa Ricardo
  21. AU="Wu, Jiangbo"
  22. AU="MacIntyre, Michael F"
  23. AU="Moon, H K"
  24. AU="Clark, Mindie"
  25. AU="Nichols, Aaron L"
  26. AU="Cash-Goldwasser, Shama"
  27. AU="Christopher B. Daniels"
  28. AU="Wakama, Hitoshi"
  29. AU="Crowe, K"
  30. AU="Merz, Sabine"
  31. AU=Rossolatos George
  32. AU="Nalla, Shahed"
  33. AU="Alvarado, Miriam"
  34. AU="Garduño-Sánchez, Marco"
  35. AU="Khan, Sherbano"
  36. AU="Kakava, Felicia"

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  1. Artikel ; Online: Assessment of rhBMP-2-loaded bovine hydroxyapatite granules in the guided bone regeneration of critical bone defect in rat mandible bone.

    López-Andaluz, J / Flores-Fraile, J / Javier-Borrajo / Blanco-Antona, L / García-Carrodeguas, R / López-Montañés, D / García-Cenador, M B / García-Criado, F J

    Journal of dental sciences

    2023  Band 19, Heft 1, Seite(n) 276–284

    Sprache Englisch
    Erscheinungsdatum 2023-04-28
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ISSN 2213-8862
    ISSN (online) 2213-8862
    DOI 10.1016/j.jds.2023.04.016
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Impact of organ confined prostate cancer treatment on quality of life.

    Alvarez-Ossorio-Rodal, A / Padilla-Fernandez, B / Muller-Arteaga, C A / Miglioni, F / Alvarez-Ossorio-Fernandez, J L / Valverde-Martínez, S / Marquez-Sanchez, M T / Flores-Fraile, M C / Linares-Mesa, N A / Miron-Canelo, J A / Garcia-Cenador, M B / Lorenzo-Gomez, M F

    Actas urologicas espanolas

    2020  Band 44, Heft 9, Seite(n) 630–636

    Abstract: Introduction: Prostate cancer (PCa) is the second most common male cancer in the world. Its incidence is estimated to grow to 1.7 million new cases and 499,000 new deaths by 2030. Treatment of OCPC can affect patients physically and mentally, as well as ...

    Titelübersetzung Impacto en la calidad de vida del tratamiento del cáncer de próstata organoconfinado.
    Abstract Introduction: Prostate cancer (PCa) is the second most common male cancer in the world. Its incidence is estimated to grow to 1.7 million new cases and 499,000 new deaths by 2030. Treatment of OCPC can affect patients physically and mentally, as well as their close relationships and their job or career, which conditions health-related quality of life (QoL).
    Objective: Evaluate the impact on QoL attributable to the treatment for Organ Confined Prostate Cancer (OCPC).
    Materials and methods: Prospective multicenter observational study of 406 patients with OCPC treated from January 2015 to June 2018. The sample was divided into four study groups, according to the type of treatment: radical prostatectomy (RP) (GA), external radiotherapy (ERT) (GB), brachytherapy (BT) (GC) and other treatments different from monotherapy with RP, ERT or BT (GD).
    Results: The age in GC was lower, the mean Prostate Specific Antigen (PSA) of all patients was 8.13 ng/ml, the group with the highest mean PSA was GB with a mean of 10.43 ng/dL, the mean Tumor Stage (TNM) was 3.82, and GD had the lowest post treatment quality of life.
    Conclusion: OCPC treatment affects QoL. Curative monotherapies, specifically RP and BT, have less effect on QoL than external radiotherapy or other therapeutic alternatives. Urinary incontinence and fistulas secondary to OCPC have the highest impact on QOL impairment. The internationally validated SF 36 questionnaire is a useful cross-sectional measure of QOL to compare the impact of OCPC treatment modalities.
    Mesh-Begriff(e) Aged ; Humans ; Male ; Middle Aged ; Prospective Studies ; Prostatic Neoplasms/pathology ; Prostatic Neoplasms/therapy ; Quality of Life
    Sprache Spanisch
    Erscheinungsdatum 2020-09-17
    Erscheinungsland Spain
    Dokumenttyp Journal Article ; Multicenter Study ; Observational Study ; Research Support, Non-U.S. Gov't
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuro.2020.05.002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: The influence of smoking on bacterial resistance after vaccine or antibiotic prophylaxis against recurrent urinary tract infections.

    Lorenzo-Gómez, M F / Santos-Antunes, M T / Nieto-Huertos, A / Lorenzo-Gómez, A / Marquez-Sanchez, M T / Flores-Fraile, M C / Valverde-Martinez, L S / González-Casado, I / García-Cenador, M B / Mirón-Canelo, J A / Padilla-Fernández, B

    Actas urologicas espanolas

    2020  Band 44, Heft 7, Seite(n) 497–504

    Abstract: Introduction: The influence of tobacco on the microbiological spectrum, resistance-sensitivity pattern and evolution in patients with recurrent urinary tract infections (RUTI) is analyzed. Evaluation of the effect of polyvalent bacterial vaccine on the ... ...

    Titelübersetzung Influencia del tabaquismo en la resistencia bacteriana después de la profilaxis frente a infecciones urinarias recurrentes con antibiótico o con vacuna.
    Abstract Introduction: The influence of tobacco on the microbiological spectrum, resistance-sensitivity pattern and evolution in patients with recurrent urinary tract infections (RUTI) is analyzed. Evaluation of the effect of polyvalent bacterial vaccine on the prevention of RUTI and smoking status.
    Material and methods: Retrospective multicenter study of 855 women with RUTI receiving suppressive antibiotic treatment or bacterial vaccine between 2009 and 2013. Group A (GA): Antibiotic (n=495); Subgroups: GA1 non-smoker (n=417), GA2 smoker (n=78). Group B (GB): Vaccine (n=360); Subgroups: GB1 non-smoker (n=263), GB2 smoker (n=97).
    Variables: Age, pre-treatment UTI, disease-free time (DFT), microbial species, sensitivity and resistance. Follow-up at 3, 6 and 12 months with culture and SF-36 questionnaire.
    Results: Mean age 56.51 years (18-75), similar between groups (P=.2257). No difference in the number of pretreatment UTIs (P=.1329) or in the distribution of the bacterial spectrum (P=.7471). DFT was higher in subgroups B compared with A. Urine cultures in GA1: E. coli 62.71% with 8.10% resistance (33% quinolones; 33% cotrimoxazole; 33% quinolones + cotrimoxazole); in GA2 E. coli 61.53% with 75% resistance (16.66% quinolones; 33.33% quinolones + cotrimoxazole; 16.66% amoxicillin-clavulanate; 16.66% erythromycin + phosphomycin + clindamycin) (P=.0133). There were no differences between patients of GA treated with cotrimoxazole and nitrofurantoin (P=.8724). Urine cultures in GB1: E. coli 47.36% with 22.22% resistance (5.55% ciprofloxacin; 5.55% cotrimoxazole; 5.55% ciprofloxacin + cotrimoxazole; 5.55% amoxicillin/clavulanic acid). In GB2 E. coli 70.02% with 61.90% resistances (30.76% quinolones; 30.76% cotrimoxazole; 30.76% quinolones + cotrimoxazole; 17.69% amoxicillin-clavulanic acid) (P=.0144).
    Conclusions: The development of bacterial resistance is more frequent among women with smoking habits and recurrent urinary infections. This could influence a worse response to preventive treatments, either with antibiotics or vaccines.
    Mesh-Begriff(e) Adolescent ; Adult ; Aged ; Antibiotic Prophylaxis ; Bacterial Infections/drug therapy ; Bacterial Infections/prevention & control ; Bacterial Vaccines ; Drug Resistance, Bacterial ; Female ; Humans ; Middle Aged ; Recurrence ; Retrospective Studies ; Smoking/adverse effects ; Urinary Tract Infections/drug therapy ; Urinary Tract Infections/microbiology ; Young Adult
    Chemische Substanzen Bacterial Vaccines
    Sprache Spanisch
    Erscheinungsdatum 2020-06-25
    Erscheinungsland Spain
    Dokumenttyp Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuro.2020.04.002
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Research of the impact of urinary infection teaching methods on the learning process.

    Lorenzo Gómez, M F / Martín Gómez, L / González Rayo, L A / Bravo Grande, J L / Padilla Fernández, B / Muñoz Lucas, M Á / Quintana-Díaz, M / Mirón Canelo, J A / García Cenador, M B / Esteban Fuertes, M

    Actas urologicas espanolas

    2019  Band 43, Heft 6, Seite(n) 314–323

    Abstract: Introduction: The classical teaching methodology was based on passive transmission-based learning. The model has changed towards an orientation based on student-centred learning.: Objective: The objective of the study has been to evaluate the ... ...

    Titelübersetzung Investigación de la repercusión en el proceso de aprendizaje según la metodología docente en la infección urinaria.
    Abstract Introduction: The classical teaching methodology was based on passive transmission-based learning. The model has changed towards an orientation based on student-centred learning.
    Objective: The objective of the study has been to evaluate the students' perception when learning about urinary tract infections, and their perspective about the teaching imparted on this pathology in the various subjects that include ITU in their syllabus.
    Methods: A cross-sectional analytical study of the responses to an anonymous survey entitled: "Methodology on urine infections. Teaching aspects "issued by 228 students at their fifth year of Medical School, from two promotions. They referred to the following subjects: Pharmacy, Pathophisiology, Gynecology and Obstetrics, Infectious diseases, Microbiology, Nephrology, Pediatrics and Urology.
    Results: The following variables have been analysed: teaching content, teaching basic aspects of the disease, consideration of teaching methodology and improvement suggestions. Descriptive and inferential statistics were used.
    Conclusion: The study has concluded that teaching urinary tract infection is perceived in specific subjects related to microorganism (Microbiology), the target organ (Infectious diseases, Urology), affected patients (Pediatrics, Gynecology and Obstetrics) rather than transversal subjects such as Pathophysiology or Pharmacy. The teaching methodology has been considered appropriate by more than 50% of the students in five from the 8 subjects that teach the concept of urinary tract infection. The students suggest convenient changes in current teaching methodology in several subjects that impart the urinary tract infection concept.
    Mesh-Begriff(e) Cross-Sectional Studies ; Curriculum ; Drug Resistance, Bacterial ; Education, Medical/methods ; Educational Measurement/statistics & numerical data ; Gynecology/education ; Humans ; Life Style ; Microbiology/education ; Nephrology/education ; Obstetrics/education ; Pediatrics/education ; Pharmacology, Clinical/education ; Physiology/education ; Problem-Based Learning/methods ; Spain ; Teaching ; Urinary Tract Infections/diagnosis ; Urinary Tract Infections/etiology ; Urinary Tract Infections/therapy ; Urology/education
    Sprache Spanisch
    Erscheinungsdatum 2019-04-10
    Erscheinungsland Spain
    Dokumenttyp Journal Article
    ISSN 2173-5786
    ISSN (online) 2173-5786
    DOI 10.1016/j.acuro.2018.11.001
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Experimental murine model of renal cancer.

    Padilla-Fernández, B / García-Cenador, M B / Rodríguez-Marcos, P / López-Marcos, J F / Antúnez-Plaza, P / Silva-Abuín, J M / López-Montañés, D / García-Criado, F J / Lorenzo-Gómez, M F

    Actas urologicas espanolas

    2017  Band 41, Heft 7, Seite(n) 445–450

    Abstract: Introduction: The objective of this study was to determine the reproducibility in a murine model of renal tumours of various histological strains that could be useful for investigating the response to target drugs.: Material and methods: Development ... ...

    Titelübersetzung Modelo murino experimental de cáncer renal.
    Abstract Introduction: The objective of this study was to determine the reproducibility in a murine model of renal tumours of various histological strains that could be useful for investigating the response to target drugs.
    Material and methods: Development and analysis of the "in vivo" model: tumour xenograft of renal cell carcinomas with Balb/c nude athymic mice. Nontumourous human renal tissue was implanted in the interscapular region of 5 mice, chromophobe renal cell carcinoma was implanted in 5 mice (which, after checking its growth, was prepared for implantation in another 10 mice) and Fuhrman grade 2 clear cell renal cell carcinoma (CCRCC) was implanted in 5 mice (which was also subsequently implanted in 10 mice). We monitored the tumour size, onset of metastases and increase in size and number of tumours. When the size had reached a point greater than or equal to locally advanced or metastatic carcinoma, the animals were euthanised for a pathological and immunohistochemical study and a second phase of implantation.
    Results: The subcutaneous xenograft of the healthy tissue did not grow. The animals were euthanised at 6 months and no renal tissue was found. The chromophobe renal cell carcinoma cells grew in the initial phase (100%); however, in the second phase, we observed a chronic lymphomonocyte inflammatory reaction and a foreign body reaction. The CCRCC grew at 5-8 months both in the first and second phase (100%), maintaining the tumour type and grade.
    Conclusions: The model with athymic Balb/c nude mice is useful for reproducing CCRCC, with the same histological characteristics and aggressiveness as native human tumours, promoting the development of the second experimental phase.
    Sprache Spanisch
    Erscheinungsdatum 2017-09
    Erscheinungsland Spain
    Dokumenttyp Journal Article
    ZDB-ID 604530-3
    ISSN 1699-7980 ; 0210-4806
    ISSN (online) 1699-7980
    ISSN 0210-4806
    DOI 10.1016/j.acuro.2016.11.005
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Severe complications and failures of incontinence surgery using the Remeex(®) adjustable tension sling (external mechanical regulator).

    Lorenzo-Gómez, M F / Padilla-Fernández, B / Virseda-Rodríguez, A J / Collazos-Robles, R E / García-Cenador, M B / Mirón-Canelo, J A

    Actas urologicas espanolas

    2015  Band 39, Heft 9, Seite(n) 558–563

    Abstract: Objectives: Since 1999, we have performed implantations of Remeex® adjustable prosthetics as rescue treatment for complex or persistent stress urinary incontinence (SUI) after failure of other surgical treatments (Burch colposuspension, Marshall- ... ...

    Abstract Objectives: Since 1999, we have performed implantations of Remeex® adjustable prosthetics as rescue treatment for complex or persistent stress urinary incontinence (SUI) after failure of other surgical treatments (Burch colposuspension, Marshall-Marchetti-Krantz (MMK) or tension-free transvaginal tape [TVT] until 2003 and transobturator tape [TOT] since 2003). We present the results of our series, which include cases with severe complications.
    Material and method: Retrospective study of women diagnosed with complex or refractory SUI who underwent Remeex(®) implantation between October 1999 and December 2013. In 5 cases, we conducted cystocele correction in the same operation as the placement of the Remeex(®).
    Results: Sixty women, with a mean age of 66.87 years (range 39-85), underwent operations. The procedure was successful in 68.33% of the cases. The failures consisted of the following: 10% of the women had mixed urinary incontinence (UI) with multiple bladder diverticula; 8.33% had mild SUI; and 13.33% had urgency urination without UI. Thirty-five percent required adjustments. We recorded 3 cases with severe complications: disabling severe UI in a patient who underwent multiple operations, massive pelvic hemorrhage in a patient undergoing standard antiplatelet therapy and infected vaginal calculi measuring 7cm on an extruding Remeex thread in a paraplegic patient 4 years after the implantation.
    Conclusions: Remeex(®) is an effective and safe procedure for achieving continence in cases of complex or refractory SUI, although it is not exempt from severe complications. Following rigorous protocols can help detect complications and treat them in a timely manner.
    Mesh-Begriff(e) Aged ; Aged, 80 and over ; Female ; Humans ; Middle Aged ; Postoperative Complications/etiology ; Prosthesis Design ; Retrospective Studies ; Severity of Illness Index ; Suburethral Slings/adverse effects ; Treatment Failure ; Urinary Incontinence, Stress/surgery ; Urologic Surgical Procedures/adverse effects ; Urologic Surgical Procedures/methods
    Sprache Spanisch
    Erscheinungsdatum 2015-11
    Erscheinungsland Spain
    Dokumenttyp Case Reports ; Journal Article
    ZDB-ID 604530-3
    ISSN 1699-7980 ; 0210-4806
    ISSN (online) 1699-7980
    ISSN 0210-4806
    DOI 10.1016/j.acuro.2015.05.001
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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