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  1. Article ; Online: Blue rubber bleb nevus syndrome successfully treated with sirolimus: a report of five pediatric patients.

    Gonzalez-Magaña, Regina / García-Romero, Maria Teresa / Durán-McKinster, Carola

    International journal of dermatology

    2024  

    Language English
    Publishing date 2024-04-28
    Publishing country England
    Document type Letter
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.17217
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  2. Article ; Online: Early-onset juvenile dermatomyositis: A report of two cases and review of the literature.

    Barrón-Calvillo, Elsa Eduwiges / García-Romero, María Teresa

    Pediatric dermatology

    2022  Volume 39, Issue 2, Page(s) 260–263

    Abstract: Juvenile dermatomyositis (JDM) is an uncommon disease in children younger than 3 years of age. The clinical manifestations may be different than in older children, often delaying the diagnosis. We present two patients with early-onset JDM and review the ... ...

    Abstract Juvenile dermatomyositis (JDM) is an uncommon disease in children younger than 3 years of age. The clinical manifestations may be different than in older children, often delaying the diagnosis. We present two patients with early-onset JDM and review the literature describing the unique clinical characteristics in this age group.
    MeSH term(s) Child ; Dermatomyositis/diagnosis ; Humans
    Language English
    Publishing date 2022-02-17
    Publishing country United States
    Document type Case Reports ; Review
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.14930
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  3. Article ; Online: The use of mTOR inhibitors for the treatment of kaposiform hemangioendothelioma. A systematic review.

    Maza-Morales, Mariana / Valdés-Loperena, Sofía / Durán-McKinster, Lourdes Carola / García-Romero, María Teresa

    Pediatric dermatology

    2023  Volume 40, Issue 3, Page(s) 440–445

    Abstract: Background: Kaposiform hemangioendothelioma (KHE) is a locally aggressive and potentially lethal vascular tumor of infancy. Current consensus recommendations include the use of vincristine and/or systemic steroids as first-line treatment. Mammalian ... ...

    Abstract Background: Kaposiform hemangioendothelioma (KHE) is a locally aggressive and potentially lethal vascular tumor of infancy. Current consensus recommendations include the use of vincristine and/or systemic steroids as first-line treatment. Mammalian target of rapamycin (mTOR) inhibitors represent a promising therapy for patients with KHE. The goal of our study is to critically assess the existing literature on outcomes of patients with KHE treated with mTOR inhibitors.
    Methods: We conducted a literature search from 1 January 2000, to 30 April 2022. Articles reporting outcomes of patients treated with mTOR inhibitors for KHE were included. Descriptive statistics were used to describe and summarize the outcomes of the treatment.
    Results: We included 327 patients with a mean age at diagnosis of 9.1 months (SD ± 9). Patients were treated with an mTOR inhibitor for a mean of 15.2 months (SD ± 4.1). A total of 315 (96.3%) patients had positive outcomes including improvement of the tumor size, symptoms and/or laboratory parameters in 227 (85%) and complete remission in 38 (12%). Seven (2%) patients did not respond to treatment and seven (2%) died of sepsis (4), Kasabach-Merritt phenomenon complications (1), cardiac and liver failure due to ductus arteriosus (1), or metastatic disease (1).
    Conclusion: This systematic review supports the efficacy and safety of mTOR inhibitors for KHE. Their use resulted in positive outcomes in terms of decreased symptoms, reduction in tumor size and improvement in biochemical parameters with a mortality rate of 2%. According to these findings, we suggest revised consensus treatment guidelines for KHE with mTOR inhibitors potentially considered first-line therapy.
    MeSH term(s) Humans ; Infant ; Kasabach-Merritt Syndrome/diagnosis ; Sirolimus/therapeutic use ; MTOR Inhibitors ; Hemangioendothelioma/diagnosis ; Sarcoma, Kaposi/complications ; TOR Serine-Threonine Kinases/therapeutic use
    Chemical Substances Sirolimus (W36ZG6FT64) ; MTOR Inhibitors ; TOR Serine-Threonine Kinases (EC 2.7.11.1) ; MTOR protein, human (EC 2.7.1.1)
    Language English
    Publishing date 2023-01-30
    Publishing country United States
    Document type Systematic Review ; Journal Article
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.15262
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  4. Article: Morphea: a practical review of its diagnosis, classification and treatment.

    Rodríguez-Salgado, Pamela / García-Romero, María Teresa

    Gaceta medica de Mexico

    2020  Volume 155, Issue 5, Page(s) 483–491

    Abstract: Morphea, or localized scleroderma, is a rare disease of the connective tissue that manifests itself with localized sclerosis of the skin and, in some cases, with extracutaneous manifestations. Its etiology is not fully understood, but it is believed that ...

    Abstract Morphea, or localized scleroderma, is a rare disease of the connective tissue that manifests itself with localized sclerosis of the skin and, in some cases, with extracutaneous manifestations. Its etiology is not fully understood, but it is believed that there is genetic predisposition, in addition to environmental triggering factors. Classification of the disease is not simple due to its multiple presentations; however, it is useful in order to define the treatment, which should be individualized and started early to avoid cosmetic and functional complications. In this review, we summarize the most important practical aspects of the classification, diagnostic methods and evaluation of morphea activity, as well as available therapeutic options, with an emphasis on existing clinical evidence regarding their efficacy and safety.
    MeSH term(s) Exercise Therapy ; Female ; Humans ; Immunosuppressive Agents ; Male ; Phototherapy/methods ; Prognosis ; Scleroderma, Localized/classification ; Scleroderma, Localized/diagnosis ; Scleroderma, Localized/etiology ; Scleroderma, Localized/therapy ; Severity of Illness Index ; Sex Factors
    Chemical Substances Immunosuppressive Agents
    Language English
    Publishing date 2020-02-24
    Publishing country Mexico
    Document type Journal Article ; Review
    ZDB-ID 425456-9
    ISSN 0016-3813
    ISSN 0016-3813
    DOI 10.24875/GMM.M20000336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Polypoid tumor of penis in an adolescent boy.

    Maza-Morales, Mariana / Corcuera-Delgado, Celso Tomás / Becerril-Cholula, Laura / García-Romero, María Teresa

    Pediatric dermatology

    2022  Volume 39, Issue 1, Page(s) e3–e4

    MeSH term(s) Adolescent ; Circumcision, Male ; Humans ; Male ; Neoplasms ; Penis
    Language English
    Publishing date 2022-02-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.14863
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  6. Article ; Online: Atypical purpura and other features associated with unfavorable outcomes of IgA vasculitis (Henoch-Schönlein purpura) in children: A retrospective study.

    Carmona-Cruz, Silvia Angélica / Durán-McKinster, Lourdes Carola / García-Romero, María Teresa

    Pediatric dermatology

    2022  Volume 39, Issue 3, Page(s) 369–371

    Abstract: The prognosis of IgA vasculitis (also known as Henoch-Schönlein purpura) is determined by renal or other organ involvement. We conducted a retrospective study to identify the initial features of 106 children with IgA vasculitis and their association with ...

    Abstract The prognosis of IgA vasculitis (also known as Henoch-Schönlein purpura) is determined by renal or other organ involvement. We conducted a retrospective study to identify the initial features of 106 children with IgA vasculitis and their association with unfavorable outcomes. Location of purpura above the waist and an altered urinalysis at diagnosis predicted a more aggressive course of disease.
    MeSH term(s) Child ; Humans ; IgA Vasculitis/complications ; IgA Vasculitis/diagnosis ; Kidney ; Prognosis ; Retrospective Studies
    Language English
    Publishing date 2022-02-17
    Publishing country United States
    Document type Journal Article
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.14927
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  7. Article ; Online: Covid-19 mortality in children and adolescents in Mexico.

    Stern, Dalia / Arias-de la Garza, Eduardo / García-Romero, María Teresa / Lajous, Martin

    Salud publica de Mexico

    2022  Volume 64, Issue 3, may-jun, Page(s) 328–332

    Abstract: Objective: To estimate Covid-19 and pre-pandemic low respiratory infection (LRI) mortality in children and adolescents in Mexico.: Materials and methods: We estimated the percentage of total mortality attributable to Covid-19 (95% confidence ... ...

    Abstract Objective: To estimate Covid-19 and pre-pandemic low respiratory infection (LRI) mortality in children and adolescents in Mexico.
    Materials and methods: We estimated the percentage of total mortality attributable to Covid-19 (95% confidence intervals; 95%CI) and made the corresponding estimates for pre-pandemic LRI mortality.
    Results: In 2019, LRIs represented 8.6% (95%CI 8.3, 8.9) of deaths in children aged 0-9 years, and 2.0% (95%CI 1.8, 2.3) in those aged 10-19 years. In 2020, the corresponding estimates for Covid-19 were 4.4% (95%CI 4.1, 4.6) and 3.7% (95%CI 3.4, 4.1).
    Conclusions: Relative to LRI, Covid-19 may be exerting a considerable mortality burden, particularly in older children and adolescents.
    MeSH term(s) Adolescent ; COVID-19 ; Child ; Humans ; Mexico/epidemiology ; Respiratory Tract Infections
    Language English
    Publishing date 2022-06-02
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 954220-6
    ISSN 1606-7916 ; 0036-3634
    ISSN (online) 1606-7916
    ISSN 0036-3634
    DOI 10.21149/13211
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Morfea: revisión práctica de su diagnóstico, clasificación y tratamiento.

    Rodríguez-Salgado, Pamela / García-Romero, María Teresa

    Gaceta medica de Mexico

    2019  Volume 155, Issue 5, Page(s) 522–531

    Abstract: Morphea, or localized scleroderma, is a rare disease of the connective tissue that manifests itself with localized sclerosis of the skin and, in some cases, with extracutaneous manifestations. Its etiology is not fully understood, but it is believed that ...

    Abstract Morphea, or localized scleroderma, is a rare disease of the connective tissue that manifests itself with localized sclerosis of the skin and, in some cases, with extracutaneous manifestations. Its etiology is not fully understood, but it is believed that there is genetic predisposition, in addition to environmental triggering factors. Classification of the disease is not simple due to its multiple presentations; however, it is useful in order to define the treatment, which should be individualized and started early to avoid cosmetic and functional complications. In this review, we summarize the most important practical aspects of the classification, diagnostic methods and evaluation of morphea activity, as well as available therapeutic options, with an emphasis on existing clinical evidence regarding their efficacy and safety.
    MeSH term(s) Gene-Environment Interaction ; Genetic Predisposition to Disease ; Humans ; Rare Diseases/classification ; Rare Diseases/diagnosis ; Rare Diseases/pathology ; Rare Diseases/therapy ; Scleroderma, Localized/classification ; Scleroderma, Localized/diagnosis ; Scleroderma, Localized/pathology ; Scleroderma, Localized/therapy
    Language English
    Publishing date 2019-11-06
    Publishing country Mexico
    Document type Journal Article ; Review
    ZDB-ID 425456-9
    ISSN 0016-3813
    ISSN 0016-3813
    DOI 10.24875/GMM.18004288
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Peristomal umbilicated papules in a child.

    Morán-Villaseñor, Edna / García-Romero, María Teresa

    Pediatric dermatology

    2019  Volume 36, Issue 5, Page(s) 713–715

    MeSH term(s) Child ; Cystostomy/adverse effects ; Dermatologic Agents/therapeutic use ; Female ; Humans ; Skin Diseases, Vesiculobullous/drug therapy ; Skin Diseases, Vesiculobullous/pathology ; Zinc Oxide/therapeutic use
    Chemical Substances Dermatologic Agents ; Zinc Oxide (SOI2LOH54Z)
    Language English
    Publishing date 2019-09-18
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 605539-4
    ISSN 1525-1470 ; 0736-8046
    ISSN (online) 1525-1470
    ISSN 0736-8046
    DOI 10.1111/pde.13901
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  10. Article ; Online: Onychomycosis in children. A review.

    Solís-Arias, Martha Patricia / García-Romero, Maria Teresa

    International journal of dermatology

    2017  Volume 56, Issue 2, Page(s) 123–130

    Abstract: Onychomycosis is considered an age-related infection with increasing prevalence in the older age groups. It is rare in the pediatric population, except in children with Down syndrome and with immunodeficiencies, who are more likely to have fungal nail ... ...

    Abstract Onychomycosis is considered an age-related infection with increasing prevalence in the older age groups. It is rare in the pediatric population, except in children with Down syndrome and with immunodeficiencies, who are more likely to have fungal nail infections. The number of reports about onychomycosis in children is relatively small, and the epidemiologic data vary, but a rise in prevalence has been demonstrated. In this article, we review the most up-to-date literature and summarize the epidemiology, etiology, clinical presentation, diagnosis, and treatment of onychomycosis in children, as well as the differences with the disease presenting in adults. Dermatologists must consider onychomycosis in the differential diagnosis of nail alterations in children and always perform a mycological study to confirm the diagnosis.
    MeSH term(s) Administration, Oral ; Administration, Topical ; Adolescent ; Antifungal Agents/administration & dosage ; Antifungal Agents/adverse effects ; Antifungal Agents/therapeutic use ; Child ; Child, Preschool ; Fluconazole/therapeutic use ; Humans ; Infant ; Itraconazole/therapeutic use ; Naphthalenes/therapeutic use ; Onychomycosis/diagnosis ; Onychomycosis/drug therapy ; Onychomycosis/epidemiology ; Onychomycosis/microbiology
    Chemical Substances Antifungal Agents ; Naphthalenes ; Itraconazole (304NUG5GF4) ; Fluconazole (8VZV102JFY) ; terbinafine (G7RIW8S0XP)
    Language English
    Publishing date 2017-02
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 412254-9
    ISSN 1365-4632 ; 0011-9059 ; 1461-1244
    ISSN (online) 1365-4632
    ISSN 0011-9059 ; 1461-1244
    DOI 10.1111/ijd.13392
    Database MEDical Literature Analysis and Retrieval System OnLINE

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