Article ; Online: Anti-inflammatory mechanisms and pharmacological actions of phycocyanobilin in a mouse model of experimental autoimmune encephalomyelitis: A therapeutic promise for multiple sclerosis.
2022 Volume 13, Page(s) 1036200
Abstract: Cytokines, demyelination and neuroaxonal degeneration in the central nervous system are pivotal elements implicated in the pathogenesis of multiple sclerosis (MS) and its nonclinical model of experimental autoimmune encephalomyelitis (EAE). ... ...
| Abstract | Cytokines, demyelination and neuroaxonal degeneration in the central nervous system are pivotal elements implicated in the pathogenesis of multiple sclerosis (MS) and its nonclinical model of experimental autoimmune encephalomyelitis (EAE). Phycocyanobilin (PCB), a chromophore of the biliprotein C-Phycocyanin (C-PC) from |
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| MeSH term(s) | Female ; Animals ; Mice ; Encephalomyelitis, Autoimmune, Experimental ; Phycocyanin/adverse effects ; Multiple Sclerosis/drug therapy ; Mice, Inbred C57BL ; Anti-Inflammatory Agents/adverse effects ; Disease Models, Animal ; Cytokines/therapeutic use ; Interferon-beta/therapeutic use |
| Chemical Substances | phycocyanobilin (36NUT04V2K) ; Phycocyanin (11016-15-2) ; Anti-Inflammatory Agents ; Cytokines ; Interferon-beta (77238-31-4) |
| Language | English |
| Publishing date | 2022-11-03 |
| Publishing country | Switzerland |
| Document type | Journal Article ; Research Support, Non-U.S. Gov't |
| ZDB-ID | 2606827-8 |
| ISSN | 1664-3224 ; 1664-3224 |
| ISSN (online) | 1664-3224 |
| ISSN | 1664-3224 |
| DOI | 10.3389/fimmu.2022.1036200 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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