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  1. Article: The coexistence of diabetic retinopathy and diabetic nephropathy is associated with worse kidney outcomes.

    Bermejo, Sheila / González, Ester / López-Revuelta, Katia / Ibernon, Meritxell / López, Diana / Martín-Gómez, Adoración / Garcia-Osuna, Rosa / Linares, Tania / Díaz, Montserrat / Martín, Nàdia / Barros, Xoana / Marco, Helena / Navarro, Maruja Isabel / Esparza, Noemí / Elias, Sandra / Coloma, Ana / Robles, Nicolás Roberto / Agraz, Irene / Poch, Esteban /
    Rodas, Lida / Lozano, Víctor / Fernández-Fernández, Beatriz / Hernández, Eduardo / Martínez, Maria Isabel / Stanescu, Ramona Ionela / Moirón, José Pelayo / García-Fernández, Núria / Goicoechea, Marian / Calero, Francesca / Bonet, Josep / Liaño, Fernando / Pascual, Julio / Bestard, Oriol / Praga, Manuel / Fulladosa, Xavier / Soler, María José

    Clinical kidney journal

    2023  Volume 16, Issue 10, Page(s) 1656–1663

    Abstract: Background: Up to 50-60% of patients with diabetes have non-diabetic kidney disease (NDKD) on kidney biopsy. Diabetic retinopathy (DR) is a microvascular complication of diabetes frequently associated with diabetic nephropathy (DN). The objective of the ...

    Abstract Background: Up to 50-60% of patients with diabetes have non-diabetic kidney disease (NDKD) on kidney biopsy. Diabetic retinopathy (DR) is a microvascular complication of diabetes frequently associated with diabetic nephropathy (DN). The objective of the current study was to investigate the kidney outcomes and survival in patients with biopsy diagnoses of DN and NDKD according to the presence of DR.
    Methods: We conducted an observational, multicentre and retrospective study of the pathological findings of renal biopsies from 832 consecutive patients with diabetes from 2002 to 2014 from 18 nephrology departments. The association of DR with kidney replacement therapy (KRT) or survival was assessed by Kaplan-Meier and Cox regression analyses.
    Results: Of 832 patients with diabetes and renal biopsy, 768 had a retinal examination and 221/768 (22.6%) had DR. During a follow-up of 10 years, 288/760 (37.9%) patients with follow-up data needed KRT and 157/760 (20.7%) died. The incidence of KRT was higher among patients with DN (alone or with NDKD) and DR [103/175 (58.9%)] than among patients without DR [88/216 (40.7%),
    Conclusions: DR is associated with a higher risk of progression to kidney failure in patients with histological DN and in patients with NDKD.
    Language English
    Publishing date 2023-07-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfad142
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6587: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Risk factors for non-diabetic renal disease in diabetic patients.

    Bermejo, Sheila / González, Ester / López-Revuelta, Katia / Ibernon, Meritxell / López, Diana / Martín-Gómez, Adoración / Garcia-Osuna, Rosa / Linares, Tania / Díaz, Montserrat / Martín, Nàdia / Barros, Xoana / Marco, Helena / Navarro, Maruja Isabel / Esparza, Noemí / Elias, Sandra / Coloma, Ana / Robles, Nicolás Roberto / Agraz, Irene / Poch, Esteban /
    Rodas, Lida / Lozano, Víctor / Fernández, Beatriz / Hernández, Eduardo / Martínez, Maria Isabel / Stanescu, Ramona Ionela / Moirón, José Pelayo / García, Núria / Goicoechea, Marian / Calero, Francesca / Bonet, Josep / Galceran, Josep M / Liaño, Fernando / Pascual, Julio / Praga, Manuel / Fulladosa, Xavier / Soler, María José

    Clinical kidney journal

    2020  Volume 13, Issue 3, Page(s) 380–388

    Abstract: Background: Diabetic patients with kidney disease have a high prevalence of non-diabetic renal disease (NDRD). Renal and patient survival regarding the diagnosis of diabetic nephropathy (DN) or NDRD have not been widely studied. The aim of our study is ... ...

    Abstract Background: Diabetic patients with kidney disease have a high prevalence of non-diabetic renal disease (NDRD). Renal and patient survival regarding the diagnosis of diabetic nephropathy (DN) or NDRD have not been widely studied. The aim of our study is to evaluate the prevalence of NDRD in patients with diabetes and to determine the capacity of clinical and analytical data in the prediction of NDRD. In addition, we will study renal and patient prognosis according to the renal biopsy findings in patients with diabetes.
    Methods: Retrospective multicentre observational study of renal biopsies performed in patients with diabetes from 2002 to 2014.
    Results: In total, 832 patients were included: 621 men (74.6%), mean age of 61.7 ± 12.8 years, creatinine was 2.8 ± 2.2 mg/dL and proteinuria 2.7 (interquartile range: 1.2-5.4) g/24 h. About 39.5% (
    Conclusions: The most frequent cause of NDRD is NAS. Elderly patients with microhaematuria and the absence of DR are the ones at risk for NDRD. Patients with DN presented worse renal prognosis and higher mortality than those with NDRD. These results suggest that in some patients with diabetes, kidney biopsy may be useful for an accurate renal diagnosis and subsequently treatment and prognosis.
    Language English
    Publishing date 2020-01-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfz177
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6587: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: IgA Nephropathy in Elderly Patients.

    Sevillano, Angel M / Diaz, Monserrat / Caravaca-Fontán, Fernando / Barrios, Clara / Bernis, Carmen / Cabrera, Jimena / Calviño, Jesus / Castillo, Lorena / Cobelo, Carmen / Delgado-Mallén, Patricia / Espinosa, Mario / Fernandez-Juarez, Gema / Fernandez-Reyes, Maria Jose / Garcia-Osuna, Rosa / Garcia, Patricia / Goicoechea, Marian / Gonzalez-Cabrera, Fayna / Guzmán, Diomaris A / Heras, Manuel /
    Martín-Reyes, Guillermo / Martinez, Alberto / Olea, Teresa / Peña, Jessy Korina / Quintana, Luis F / Rabasco, Cristina / López Revuelta, Katia / Rodas, Lida / Rodriguez-Mendiola, Nuria / Rodriguez, Eva / San Miguel, Luz / Sanchez de la Nieta, Maria Dolores / Shabaka, Amir / Sierra, Milagros / Valera, Alfonso / Velo, Mercedes / Verde, Eduardo / Ballarin, Jose / Noboa, Oscar / Moreno, Juan Antonio / Gutiérrez, Eduardo / Praga, Manuel

    Clinical journal of the American Society of Nephrology : CJASN

    2019  Volume 14, Issue 8, Page(s) 1183–1192

    Abstract: Background and objectives: Some studies suggest that the incidence of IgA nephropathy is increasing in older adults, but there is a lack of information about the epidemiology and behavior of the disease in that age group.: Design, setting, ... ...

    Abstract Background and objectives: Some studies suggest that the incidence of IgA nephropathy is increasing in older adults, but there is a lack of information about the epidemiology and behavior of the disease in that age group.
    Design, setting, participants, & measurements: In this retrospective multicentric study, we analyzed the incidence, forms of presentation, clinical and histologic characteristics, treatments received, and outcomes in a cohort of 151 patients ≥65 years old with biopsy-proven IgA nephropathy diagnosed between 1990 and 2015. The main outcome was a composite end point of kidney replacement therapy or death before kidney replacement therapy.
    Results: We found a significant increase in the diagnosis of IgA nephropathy over time from six patients in 1990-1995 to 62 in 2011-2015 (
    Conclusions: The diagnosis of IgA nephropathy among older adults in Spain has progressively increased in recent years, and anticoagulant therapy may be partially responsible for this trend. Prognosis was poor.
    Podcast: This article contains a podcast at https://www.asn-online.org/media/podcast/CJASN/2019_07_16_CJASNPodcast_19_08_.mp3.
    MeSH term(s) Adult ; Aged ; Female ; Glomerulonephritis, IGA/diagnosis ; Glomerulonephritis, IGA/epidemiology ; Glomerulonephritis, IGA/therapy ; Humans ; Incidence ; Male ; Middle Aged ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2019-07-16
    Publishing country United States
    Document type Journal Article ; Multicenter Study ; Research Support, Non-U.S. Gov't
    ZDB-ID 2226665-3
    ISSN 1555-905X ; 1555-9041
    ISSN (online) 1555-905X
    ISSN 1555-9041
    DOI 10.2215/CJN.13251118
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6584: Show issues Location:
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