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  1. Article ; Online: Human Ultraweak Photon Emission: Key Analytical Aspects, Results and Future Trends - A Review.

    Calcerrada, M / Garcia-Ruiz, C

    Critical reviews in analytical chemistry

    2018  Volume 49, Issue 4, Page(s) 368–381

    Abstract: Living systems emit what is called ultraweak photon emission (UPE). This visually undetectable phenomenon has only been studied in humans for the last 30 years, finding that UPE is a complex process depending on multitude factors. Considering previous ... ...

    Abstract Living systems emit what is called ultraweak photon emission (UPE). This visually undetectable phenomenon has only been studied in humans for the last 30 years, finding that UPE is a complex process depending on multitude factors. Considering previous literature, this review discusses the current trends in the analysis of in vivo UPE from human beings. To this aim, Analytical Approaches Employed for UPE Measurement section focuses on the analytical techniques employed (photomultipliers and charged coupled device cameras), summarizing analytical conditions and reporting figures of merit reached to date. Then, Human UPE Depending on External Factors and Human UPE Depending on Internal Factors sections address external and internal factors, which have proved to affect UPE, pointing out the important influence on oxidative processes outside and inside the body, and also highlighting some personal states of the individuals affecting UPE. Last section is devoted to give a general view on the goals and achieved up to date regarding UPE measurement, emphasizing some potential applications as well as recommendations which include: use of UPE spectra information together with UPE intensity, larger populations (≈50-100 subjects), further studies on internal states of individuals, and use of statistical tools.
    MeSH term(s) Human Body ; Humans ; Photons
    Language English
    Publishing date 2018-12-24
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2030019-0
    ISSN 1547-6510 ; 1040-8347
    ISSN (online) 1547-6510
    ISSN 1040-8347
    DOI 10.1080/10408347.2018.1534199
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: HILPDA, a new player in NASH-driven HCC, links hypoxia signaling with ceramide synthesis.

    Fernandez-Checa, Jose C / Torres, Sandra / Garcia-Ruiz, Carmen

    Journal of hepatology

    2023  Volume 79, Issue 2, Page(s) 269–272

    MeSH term(s) Humans ; Carcinoma, Hepatocellular/etiology ; Liver Neoplasms/etiology ; Non-alcoholic Fatty Liver Disease/complications ; Hypoxia ; Ceramides
    Chemical Substances Ceramides
    Language English
    Publishing date 2023-05-17
    Publishing country Netherlands
    Document type Editorial ; Comment
    ZDB-ID 605953-3
    ISSN 1600-0641 ; 0168-8278
    ISSN (online) 1600-0641
    ISSN 0168-8278
    DOI 10.1016/j.jhep.2023.05.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Chemical Classification of Explosives.

    Zapata, Félix / García-Ruiz, Carmen

    Critical reviews in analytical chemistry

    2020  Volume 51, Issue 7, Page(s) 656–673

    Abstract: This work comprehensively reviews some fundamental concepts about explosives and their two commonly used classifications based on either their velocity of detonation or their application. These classifications are highly useful in the military/legal ... ...

    Abstract This work comprehensively reviews some fundamental concepts about explosives and their two commonly used classifications based on either their velocity of detonation or their application. These classifications are highly useful in the military/legal field, but completely useless for the chemical determination of explosives. Because of this reason, a classification of explosives based on their chemical composition is comprehensively revised, discussed and updated. This classification seeks to merge those dispersed chemical classifications of explosives found in literature into a unique general classification, which might be useful for every researcher dealing with the analytical chemical identification of explosives. In the knowledge of the chemical composition of explosives, the most adequate analytical techniques to determine them are finally discussed.
    MeSH term(s) Explosions ; Explosive Agents
    Chemical Substances Explosive Agents
    Language English
    Publishing date 2020-05-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2030019-0
    ISSN 1547-6510 ; 1040-8347
    ISSN (online) 1547-6510
    ISSN 1040-8347
    DOI 10.1080/10408347.2020.1760783
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: First record of the cirripede Anelasma squalicola Darwin, 1852 (Pollicipedidae) in the Mediterranean Sea.

    Martín-Lázaro, Alba / Isbert, Wolf / Repullés-Albeda, Aigües / García-Ruiz, Cristina / Montero, Francisco E

    Zootaxa

    2023  Volume 5230, Issue 3, Page(s) 381–390

    Abstract: Anelasma squalicola Darwin 1852, is a barnacle that occurs on elasmobranchs from the Atlantic, Pacific, Arctic and Indian Ocean. It infects sharks of the families Etmopteridae and Pentanchidae. The barnacle attaches sub-dermally to its hosts, relying on ... ...

    Abstract Anelasma squalicola Darwin 1852, is a barnacle that occurs on elasmobranchs from the Atlantic, Pacific, Arctic and Indian Ocean. It infects sharks of the families Etmopteridae and Pentanchidae. The barnacle attaches sub-dermally to its hosts, relying on its interstitial fluid for its nourishment. Herein we present the first record of this species in the Mediterranean Sea, from Etmopterus spinax (Linnaeus, 1758) caught during a bottom-trawl survey in the Alboran Sea (western Mediterranean) in 2017. The overall prevalence of infection was very low (0.22%). The calculated HSI index for the parasitized individual was lower compared to overall means of other individuals and could indicate a potential physiological alteration in the host.
    MeSH term(s) Animals ; Thoracica/physiology ; Mediterranean Sea ; Sharks/physiology
    Language English
    Publishing date 2023-01-23
    Publishing country New Zealand
    Document type Journal Article
    ISSN 1175-5334
    ISSN (online) 1175-5334
    DOI 10.11646/zootaxa.5230.3.7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Differentiation of blood and environmental interfering stains on substrates by Chemometrics-Assisted ATR FTIR spectroscopy.

    Cano-Trujillo, Cristina / García-Ruiz, Carmen / Ortega-Ojeda, Fernando E / Montalvo, Gemma

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2023  Volume 292, Page(s) 122409

    Abstract: Blood is the most common and relevant bodily fluid that can be found in crime scenes. It is critical to correctly identify it, and to be able to differentiate it from other substances that may also appear at the crime scene. In this work, several stains ... ...

    Abstract Blood is the most common and relevant bodily fluid that can be found in crime scenes. It is critical to correctly identify it, and to be able to differentiate it from other substances that may also appear at the crime scene. In this work, several stains of blood, chocolate, ketchup, and tomato sauce on five different substrates (plywood, metal, gauze, denim, and glass) were analysed by ATR FTIR spectroscopy assisted with orthogonal partial least square-discriminant analysis (OPLS-DA) models. It was possible to differentiate blood from the environmental interfering substances independently of the substrate they were on, and to differentiate bloodstains according to the substrate they were deposited on. These results represent a proof-of-concept that open new horizons to differentiate bloodstains from other interfering substances on common substrates present in crime scenes.
    MeSH term(s) Coloring Agents ; Spectroscopy, Fourier Transform Infrared/methods ; Chemometrics ; Discriminant Analysis ; Least-Squares Analysis
    Chemical Substances Coloring Agents
    Language English
    Publishing date 2023-01-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2023.122409
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Identification of new psychoactive substances and their metabolites using non-targeted detection with high-resolution mass spectrometry through diagnosing fragment ions/neutral loss analysis.

    Matey, José Manuel / Zapata, Félix / Menéndez-Quintanal, Luis Manuel / Montalvo, Gemma / García-Ruiz, Carmen

    Talanta

    2023  Volume 265, Page(s) 124816

    MeSH term(s) Tandem Mass Spectrometry/methods ; Ions ; Psychotropic Drugs/analysis ; Substance Abuse Detection/methods
    Chemical Substances Ions ; Psychotropic Drugs
    Language English
    Publishing date 2023-06-28
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1500969-5
    ISSN 1873-3573 ; 0039-9140
    ISSN (online) 1873-3573
    ISSN 0039-9140
    DOI 10.1016/j.talanta.2023.124816
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Forensic analysis of biological fluid stains on substrates by spectroscopic approaches and chemometrics: A review.

    Cano-Trujillo, Cristina / García-Ruiz, Carmen / Ortega-Ojeda, Fernando E / Romolo, Francesco / Montalvo, Gemma

    Analytica chimica acta

    2023  Volume 1282, Page(s) 341841

    Abstract: Background: Bodily fluid stains are one of the most relevant evidence that can be found at the crime scene as it provides a wealth of information to the investigators. They help to report on the individuals involved in the crime, to check alibis, or to ... ...

    Abstract Background: Bodily fluid stains are one of the most relevant evidence that can be found at the crime scene as it provides a wealth of information to the investigators. They help to report on the individuals involved in the crime, to check alibis, or to determine the type of crime that has been committed. They appear as stains in different types of substrates, some of them porous, which can interfere in the analysis. The spectroscopy techniques combined with chemometrics are showing increasing potential for their use in the analysis of such samples due to them being fast, sensitive, and non-destructive.
    Findings: This is a comprehensive review of the studies that used different spectroscopic techniques followed by chemometrics for analysing biological fluid stains on several surfaces, and under various conditions. It focuses on the bodily fluid stains and the most suitable spectroscopic techniques to study forensic scientific problems such as the substrate's characteristics, the influence of ambient conditions, the aging process of the bodily fluids, the presence of animal bodily fluids and non-biological fluids (interfering substances), and the bodily fluid mixtures. The most widely used techniques were Raman spectroscopy and attenuated total reflection Fourier transform infrared spectroscopy (ATR FTIR). Nonetheless, other non-destructive techniques have been also used, like near infrared hyperspectral imaging (HSI-NIR) or surface enhanced Raman spectroscopy (SERS), among others. This work provides the criteria for the selection of the most promising non-destructive techniques for the effective in situ detection of biological fluid stains at crime scene investigations.
    Significance and novelty: The use of the proper spectroscopic and chemometric approaches on the crime scene is expected to improve the support of forensic sciences to criminal investigations. Evidence may be analysed in a non-destructive manner and kept intact for further analysis. They will also speed up forensic investigations by allowing the selection of relevant samples from occupational ones.
    MeSH term(s) Humans ; Coloring Agents ; Chemometrics ; Forensic Medicine/methods ; Forensic Sciences/methods ; Spectroscopy, Fourier Transform Infrared/methods
    Chemical Substances Coloring Agents
    Language English
    Publishing date 2023-09-26
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 1483436-4
    ISSN 1873-4324 ; 0003-2670
    ISSN (online) 1873-4324
    ISSN 0003-2670
    DOI 10.1016/j.aca.2023.341841
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: C-Reactive Protein, a Promising Approach for Acetaminophen Hepatotoxicity.

    Garcia-Ruiz, Carmen / Fernandez-Checa, Jose C

    Cellular and molecular gastroenterology and hepatology

    2021  Volume 13, Issue 1, Page(s) 341–342

    MeSH term(s) Acetaminophen ; C-Reactive Protein ; Chemical and Drug Induced Liver Injury ; Humans
    Chemical Substances Acetaminophen (362O9ITL9D) ; C-Reactive Protein (9007-41-4)
    Language English
    Publishing date 2021-10-31
    Publishing country United States
    Document type Editorial ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 2819778-1
    ISSN 2352-345X ; 2352-345X
    ISSN (online) 2352-345X
    ISSN 2352-345X
    DOI 10.1016/j.jcmgh.2021.10.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: In response to the letter "scopolamine: useful medicine or dangerous drug?".

    García-Ruiz, C / Sáiz, J

    Science & justice : journal of the Forensic Science Society

    2014  Volume 54, Issue 4, Page(s) 323

    MeSH term(s) Adjuvants, Anesthesia/chemistry ; Electric Conductivity ; Electrophoresis, Capillary/methods ; Humans ; Scopolamine Hydrobromide/chemistry ; Substance Abuse Detection/methods
    Chemical Substances Adjuvants, Anesthesia ; Scopolamine Hydrobromide (451IFR0GXB)
    Language English
    Publishing date 2014-07
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 1230910-2
    ISSN 1876-4452 ; 1355-0306
    ISSN (online) 1876-4452
    ISSN 1355-0306
    DOI 10.1016/j.scijus.2014.05.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The discrimination of 72 nitrate, chlorate and perchlorate salts using IR and Raman spectroscopy.

    Zapata, Félix / García-Ruiz, Carmen

    Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

    2018  Volume 189, Page(s) 535–542

    Abstract: Inorganic oxidizing energetic salts including nitrates, chlorates and perchlorates are widely used in the manufacture of not only licit pyrotechnic compositions, but also illicit homemade explosive mixtures. Their identification in forensic laboratories ... ...

    Abstract Inorganic oxidizing energetic salts including nitrates, chlorates and perchlorates are widely used in the manufacture of not only licit pyrotechnic compositions, but also illicit homemade explosive mixtures. Their identification in forensic laboratories is usually accomplished by either capillary electrophoresis or ion chromatography, with the disadvantage of dissociating the salt into its ions. On the contrary, vibrational spectroscopy, including IR and Raman, enables the non-invasive identification of the salt, i.e. avoiding its dissociation. This study focuses on the discrimination of all nitrate, chlorate and perchlorate salts that are commercially available, using both Raman and IR spectroscopy, with the aim of testing whether every salt can be unequivocally identified. Besides the visual spectra comparison by assigning every band with the corresponding molecular vibrational mode, a statistical analysis based on Pearson correlation was performed to ensure an objective identification, either using Raman, IR or both. Positively, 25 salts (out of 72) were unequivocally identified using Raman, 30 salts when using IR and 44 when combining both techniques. Negatively, some salts were undistinguishable even using both techniques demonstrating there are some salts that provide very similar Raman and IR spectra.
    Language English
    Publishing date 2018-01-15
    Publishing country England
    Document type Journal Article
    ZDB-ID 210413-1
    ISSN 1873-3557 ; 0370-8322 ; 0584-8539 ; 1386-1425
    ISSN (online) 1873-3557
    ISSN 0370-8322 ; 0584-8539 ; 1386-1425
    DOI 10.1016/j.saa.2017.08.058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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