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  1. Article ; Online: Persistencia de manifestaciones clínicas tras la infección COVID-19: importancia del seguimiento.

    Rosales-Castillo, Antonio / García de Los Ríos, Carlos / Mediavilla García, Juan Diego

    Medicina clinica

    2020  Volume 156, Issue 1, Page(s) 35–36

    Title translation Persistent symptoms after acute COVID-19 infection: importance of follow-up.
    MeSH term(s) Adult ; Aftercare/methods ; Aged ; Aged, 80 and over ; COVID-19/complications ; COVID-19/diagnosis ; COVID-19/therapy ; COVID-19 Testing ; Female ; Follow-Up Studies ; Hospitalization ; Humans ; Male ; Middle Aged ; Retrospective Studies
    Keywords covid19
    Language Spanish
    Publishing date 2020-09-25
    Publishing country Spain
    Document type Letter
    ZDB-ID 411607-0
    ISSN 1578-8989 ; 0025-7753
    ISSN (online) 1578-8989
    ISSN 0025-7753
    DOI 10.1016/j.medcli.2020.08.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ua VI Zs.279: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Persistent symptoms after acute COVID-19 infection: importance of follow-up.

    Rosales-Castillo, Antonio / García de Los Ríos, Carlos / Mediavilla García, Juan Diego

    Medicina clinica (English ed.)

    2020  Volume 156, Issue 1, Page(s) 35–36

    Language English
    Publishing date 2020-12-13
    Publishing country Spain
    Document type Case Reports
    ISSN 2387-0206
    ISSN (online) 2387-0206
    DOI 10.1016/j.medcle.2020.08.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Sclerostin as a biomarker of cardiovascular risk in women with systemic lupus erythematosus.

    Garcia-de Los Ríos, Carlos / Medina-Casado, Marta / Díaz-Chamorro, Antonio / Sierras-Jiménez, María / Lardelli-Claret, Pablo / Cáliz-Cáliz, Rafael / Sabio, José Mario

    Scientific reports

    2022  Volume 12, Issue 1, Page(s) 21621

    Abstract: Cardiovascular disease is one of the main causes of death in patients with systemic lupus erythematosus (SLE). On the other hand, sclerostin is a reliable and early biomarker of vascular calcification. This study aimed to estimate the association between ...

    Abstract Cardiovascular disease is one of the main causes of death in patients with systemic lupus erythematosus (SLE). On the other hand, sclerostin is a reliable and early biomarker of vascular calcification. This study aimed to estimate the association between sclerostin and two markers of cardiovascular risk, carotid atherosclerotic plaque (CP) and carotid-femoral pulse wave velocity (PWV), in women with SLE. The presence of CP (determined by carotid artery ultrasound) and PWV were measured in 68 women with SLE and preserved renal function. None of the participants had a history of cardiovascular disease. Serum levels of sclerostin were determined using the ELISA method. Other factors associated with increased cardiovascular risk were also measured. The association between sclerostin, CP and PWV was assessed using Receiver Operating Characteristic (ROC) curves and multivariate regression models. The area under the ROC curve was 0.785 (95% confidence interval [CI] 0.662-0.871) for CP and 0.834 (95% CI 0.729-0.916) for dichotomized PWV. After adjusting for other cardiovascular risk factors, it was found that a 10-units increase in sclerostin values was associated with a 44% increase in the odds of CP (95% CI 1-105), but no adjusted association was observed between sclerostin and PWV. Predictive models included age (for both outcomes), hypertension, Framingham risk score and C-reactive protein (for PWV), but not sclerostin. Sclerostin is associated with the presence of CP in women with SLE. Further research should confirm its possible role as a biomarker of cardiovascular risk in these patients.
    MeSH term(s) Humans ; Female ; Cardiovascular Diseases/etiology ; Cardiovascular Diseases/complications ; Pulse Wave Analysis ; Risk Factors ; Cross-Sectional Studies ; Lupus Erythematosus, Systemic/complications ; Biomarkers ; Heart Disease Risk Factors
    Chemical Substances Biomarkers
    Language English
    Publishing date 2022-12-14
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-022-25651-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: High-sensitivity cardiac troponin I is a biomarker for increased arterial stiffness in systemic lupus erythematous women with normal kidney function.

    Sabio, J M / Garcia-de Los Ríos, Carlos / Medina-Casado, Marta / Del Mar Del Águila-García, María / Cáliz-Cáliz, Rafael / Díaz-Chamorro, Antonio

    Rheumatology international

    2022  Volume 43, Issue 2, Page(s) 253–263

    Abstract: Cardiovascular disease (CVD) is a main cause of death in patients with systemic lupus erythematous (SLE). Algorithms for cardiovascular risk stratification in general population underestimate the risk for CVD in SLE. Our study aimed to determine whether ... ...

    Abstract Cardiovascular disease (CVD) is a main cause of death in patients with systemic lupus erythematous (SLE). Algorithms for cardiovascular risk stratification in general population underestimate the risk for CVD in SLE. Our study aimed to determine whether serum high-sensitivity cardiac troponin I (hs-cTnI) might help to identify SLE patients with subclinical atherosclerosis. Arterial stiffness was assessed measuring the carotid-femoral pulse wave velocity (PWV) in 68 SLE women with a normal or almost normal kidney function and in 71 controls of similar characteristics. None of the participants had a history of an overt CVD. Serum hs-cTnI level was measured using the chemiluminescence method. Factors associated with an increased PWV (iPWV) were identified and multivariate analysis was performed. When detectable, patients tended to have had higher hs-cTnI levels than controls [2.9 (2.3-4.0) vs 2.4 (2.2-4.1); p = 0.098] and were more likely to have detectable hs-cTnI [50% vs 28%, odds ratio (OR) 7.0; 95% confidence interval (CI) 0.008-0.013]. Also, patients with iPWV were more likely to have detectable hs-cTnI than those with normal PWV (OR 6.4; 95% CI 0.019-0.026). In the multivariate analysis, the age at SLE diagnosis (OR 1.24; 95% CI 1.04-1.48), systolic blood pressure (OR 1.28; 95% CI 1.10-1.48) and detectable hs-cTnI level (OR 2.04; 95% CI 1.18-3.50) were independently associated with an iPWV. The negative predictive value of having an iPWV with undetectable hs-cTnI levels was 88%. Hs-cTnI may be a useful biomarker for the identification of SLE patients with iPWV as a surrogated marker of subclinical atherosclerosis. Specifically targeted prospective studies are needed to confirm this hypothesis.
    MeSH term(s) Humans ; Female ; Troponin I ; Lupus Erythematosus, Systemic/complications ; Lupus Erythematosus, Systemic/diagnosis ; Vascular Stiffness/physiology ; Pulse Wave Analysis ; Biomarkers ; Atherosclerosis/diagnosis ; Atherosclerosis/complications ; Cardiovascular Diseases/etiology ; Kidney
    Chemical Substances Troponin I ; Biomarkers
    Language English
    Publishing date 2022-09-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 8286-7
    ISSN 1437-160X ; 0172-8172
    ISSN (online) 1437-160X
    ISSN 0172-8172
    DOI 10.1007/s00296-022-05204-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1639: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: Persistencia de manifestaciones clínicas tras la infección COVID-19: importancia del seguimiento./ Persistencia de manifestaciones clínicas tras la infección COVID-19: importancia del seguimiento./ Persistent symptoms after acute COVID-19 infection: importance of follow-up

    Rosales-Castillo, Antonio / García de Los Ríos, Carlos / Mediavilla García, Juan Diego

    Med. clin (Ed. impr.)

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #795685
    Database COVID19

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  6. Article ; Online: Persistencia de manifestaciones clínicas tras la infección COVID-19

    Rosales-Castillo, Antonio / García de los Ríos, Carlos / Mediavilla García, Juan Diego

    Medicina Clínica ; ISSN 0025-7753

    importancia del seguimiento

    2020  

    Keywords General Medicine ; covid19
    Language Spanish
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    DOI 10.1016/j.medcli.2020.08.001
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Progressive cardiovascular disease in a patient under treatment with nilotinib.

    Roa-Chamorro, Ricardo / Torres-Quintero, Lucía / García de Los Ríos, Carlos / Puerta-Puerta, José Manuel / González-Bustos, Pablo / Mediavilla-García, Juan Diego

    Clinica e investigacion en arteriosclerosis : publicacion oficial de la Sociedad Espanola de Arteriosclerosis

    2019  Volume 32, Issue 2, Page(s) 66–69

    Abstract: The development of cardiovascular disease appears in subjects with several cardiovascular risk factors. However, other agents could be related to the appearance of cardiovascular disease, like chemotherapy drugs. We present a 63 years-old man with very ... ...

    Title translation Enfermedad cardiovascular progresiva en paciente bajo tratamiento con nilotinib.
    Abstract The development of cardiovascular disease appears in subjects with several cardiovascular risk factors. However, other agents could be related to the appearance of cardiovascular disease, like chemotherapy drugs. We present a 63 years-old man with very high cardiovascular risk and chronic myeloid leukemia under treatment with nilotinib. Despite a good control of cardiovascular risk factors, he development a severe and accelerated peripheral arterial disease. Peripheral arterial disease occurs in 5-20% patients under treatment with nilotinib and it is more frequently in subjects with several cardiovascular risk factors.
    MeSH term(s) Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/adverse effects ; Cardiovascular Diseases/chemically induced ; Disease Progression ; Humans ; Leukemia, Myelogenous, Chronic, BCR-ABL Positive/drug therapy ; Male ; Middle Aged ; Peripheral Arterial Disease/chemically induced ; Peripheral Arterial Disease/physiopathology ; Pyrimidines/administration & dosage ; Pyrimidines/adverse effects ; Severity of Illness Index
    Chemical Substances Antineoplastic Agents ; Pyrimidines ; nilotinib (F41401512X)
    Language Spanish
    Publishing date 2019-07-04
    Publishing country Spain
    Document type Case Reports ; Journal Article
    ISSN 1578-1879
    ISSN (online) 1578-1879
    DOI 10.1016/j.arteri.2019.05.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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