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  1. Article ; Online: Alien hand syndrome-like functional seizures in a patient with right temporo-parietal damage and neurocognitive disorder: a case report.

    Mammì, Anna / Bova, Valentina / Ferlazzo, Edoardo / Pascarella, Angelo / Gasparini, Sara

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2024  

    Language English
    Publishing date 2024-03-20
    Publishing country Italy
    Document type Letter
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-024-07473-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1877: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Favorable outcome of partial splenic embolization after thrombolysis-induced splenic rupture following ischemic stroke: a case report.

    Cianci, Vittoria / Ielo, Giuseppe / Gasparini, Sara / Mechelli, Alessandro / Ferlazzo, Edoardo

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2022  Volume 43, Issue 12, Page(s) 6967–6970

    MeSH term(s) Humans ; Ischemic Stroke ; Splenic Rupture/chemically induced ; Embolization, Therapeutic ; Thrombolytic Therapy/adverse effects ; Treatment Outcome
    Language English
    Publishing date 2022-08-17
    Publishing country Italy
    Document type Case Reports ; Letter ; Comment
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-022-06341-z
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    Zs.A 1877: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  3. Article ; Online: Rapid versus slow withdrawal of antiepileptic monotherapy in two-year seizure-free adults patients with epilepsy (RASLOW) study: a pragmatic multicenter, prospective, randomized, controlled study Reply to letter to the editor.

    Ferlazzo, Edoardo / Gasparini, Sara / Giussani, Giorgia / Bianchi, Elisa / Aguglia, Umberto

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2022  Volume 44, Issue 1, Page(s) 385–387

    MeSH term(s) Adult ; Humans ; Anticonvulsants/therapeutic use ; Epilepsy/drug therapy ; Epilepsy, Generalized/drug therapy ; Prospective Studies
    Chemical Substances Anticonvulsants
    Language English
    Publishing date 2022-09-14
    Publishing country Italy
    Document type Letter ; Multicenter Study ; Pragmatic Clinical Trial ; Comment
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-022-06405-0
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1877: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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  4. Article ; Online: Sample selection and gold standard testing for a proper group comparison.

    Gasparini, Sara / Ferlazzo, Edoardo / Branca, Damiano / Aguglia, Umberto

    European journal of neurology

    2021  Volume 28, Issue 11, Page(s) e86

    MeSH term(s) Humans ; Polyradiculoneuropathy, Chronic Inflammatory Demyelinating ; Research Design
    Language English
    Publishing date 2021-09-02
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 1280785-0
    ISSN 1468-1331 ; 1351-5101 ; 1471-0552
    ISSN (online) 1468-1331
    ISSN 1351-5101 ; 1471-0552
    DOI 10.1111/ene.15076
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    Zs.A 4738: Show issues Location:
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    Zs.MO 592: Show issues

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  5. Article ; Online: Sex Differences in Adverse Effects of Antiseizure Medications in Adults with Epilepsy: A Systematic Review.

    Giuliano, Loretta / Durante, Vania / Battaglia, Giulia / Gasparini, Sara / Zambrelli, Elena / Ermio, Caterina / La Neve, Angela / Mostacci, Barbara

    CNS drugs

    2024  Volume 38, Issue 6, Page(s) 409–423

    Abstract: Background: Sex differences in epilepsy have been described in prevalence, seizure propensity and response to treatment. Therefore, taking into account sex-based differences in epilepsy is important for both diagnostic purposes and therapeutic ... ...

    Abstract Background: Sex differences in epilepsy have been described in prevalence, seizure propensity and response to treatment. Therefore, taking into account sex-based differences in epilepsy is important for both diagnostic purposes and therapeutic considerations. However, little is known about sex differences in adverse effects of antiseizure medications (ASMs).
    Objectives: We performed a systematic review searching for sex differences in adverse effects of ASMs in adult persons with epilepsy (PWE) as part of a wider project aimed to assess sex-based differences in efficacy and adverse effects of ASMs in PWE.
    Methods: We conducted a comprehensive literature search in the PubMed database. The search was conducted with no restriction on publication date, and all results up to April 2020 were included. We included articles written in English, Italian, Spanish, or French that evaluated adverse effects of one or more ASMs in PWE, with specific mention of the two sexes. When appropriate, Newcastle-Ottawa or Jadad scales were used to assess study quality.
    Results: Of 5164 identified studies, only 167 considered sex in the analysis and were therefore included. Significant sex-related differences were found in 58 of those studies. We found a consistently higher frequency of cutaneous adverse effects in females; higher risk of developing general adverse effects on different ASMs in females; stronger risk of adverse effects on bone metabolism in females, mainly on treatment with enzyme-inducing ASMs; a concordant higher risk of visual field loss was noted in males on vigabatrin; an overall worse lipid profile in males; as well as higher leptin levels and higher body mass index in females treated with various ASMs.
    Conclusions: Our analysis has identified some important sex differences in the adverse effects of ASMs. Clinicians should be aware of these differences when informing patients about the risks associated with ASM treatment in PWE.
    MeSH term(s) Humans ; Epilepsy/drug therapy ; Anticonvulsants/adverse effects ; Anticonvulsants/administration & dosage ; Female ; Male ; Sex Characteristics ; Sex Factors ; Adult
    Language English
    Publishing date 2024-04-30
    Publishing country New Zealand
    Document type Systematic Review ; Journal Article
    ZDB-ID 1203800-3
    ISSN 1179-1934 ; 1172-7047
    ISSN (online) 1179-1934
    ISSN 1172-7047
    DOI 10.1007/s40263-024-01088-x
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4083: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
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  6. Article ; Online: SMART: stroke-like migraine attacks after radiation therapy or seizures with migraine-like attacks after radiation therapy? Terms do matter in clinical practice.

    Ascoli, Michele / Ferlazzo, Edoardo / Cianci, Vittoria / Aguglia, Umberto / Gasparini, Sara

    Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology

    2021  Volume 42, Issue 8, Page(s) 3447–3448

    MeSH term(s) Humans ; Migraine Disorders/etiology ; Seizures/etiology ; Stroke
    Language English
    Publishing date 2021-04-22
    Publishing country Italy
    Document type Letter
    ZDB-ID 2016546-8
    ISSN 1590-3478 ; 1590-1874
    ISSN (online) 1590-3478
    ISSN 1590-1874
    DOI 10.1007/s10072-021-05228-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1877: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  7. Article ; Online: Testing rimegepant for migraine-time to revise the trial design?

    Gasparini, Sara / Torino, Claudia / Branca, Damiano / Ferlazzo, Edoardo / Aguglia, Umberto

    Lancet (London, England)

    2020  Volume 395, Issue 10241, Page(s) 1901

    MeSH term(s) Calcitonin Gene-Related Peptide Receptor Antagonists ; Double-Blind Method ; Humans ; Migraine Disorders ; Piperidines ; Pyridines ; Tablets
    Chemical Substances Calcitonin Gene-Related Peptide Receptor Antagonists ; Piperidines ; Pyridines ; Tablets ; rimegepant sulfate (1383NM3Q0H)
    Language English
    Publishing date 2020-06-17
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 3306-6
    ISSN 1474-547X ; 0023-7507 ; 0140-6736
    ISSN (online) 1474-547X
    ISSN 0023-7507 ; 0140-6736
    DOI 10.1016/S0140-6736(20)30241-5
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  8. Article ; Online: Cryptogenic cerebral venous thrombosis in a multiple-sclerosis-patient treated with Alemtuzumab.

    Gasparini, Sara / Russo, Margherita / Dattola, Vincenzo / Ferlazzo, Edoardo / Aguglia, Umberto

    Multiple sclerosis and related disorders

    2020  Volume 44, Page(s) 102246

    Abstract: Alemtuzumab is a highly effective treatment for relapsing-remitting multiple sclerosis (MS). Its molecular target is CD 52, a GPI-anchored protein. Herein, we describe the case of a 40-year-old man with MS treated with alemtuzumab, who developed cerebral ...

    Abstract Alemtuzumab is a highly effective treatment for relapsing-remitting multiple sclerosis (MS). Its molecular target is CD 52, a GPI-anchored protein. Herein, we describe the case of a 40-year-old man with MS treated with alemtuzumab, who developed cerebral sinus thrombosis. In the literature, alemtuzumab was associated with venous thrombosis, attributed to a paroxysmal nocturnal hemoglobinuria (PNH)-like mechanism. In our case, no PNH clones were detected. Other common causes of cerebral venous thrombosis, like infections and thrombophilia, were excluded, thus the pathogenic mechanism remains obscure.
    MeSH term(s) Adult ; Alemtuzumab/adverse effects ; Hemoglobinuria, Paroxysmal ; Humans ; Male ; Sclerosis ; Venous Thrombosis/diagnostic imaging
    Chemical Substances Alemtuzumab (3A189DH42V)
    Language English
    Publishing date 2020-05-30
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 2645330-7
    ISSN 2211-0356 ; 2211-0348
    ISSN (online) 2211-0356
    ISSN 2211-0348
    DOI 10.1016/j.msard.2020.102246
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  9. Article: Epidemiology and Outcomes of Status Epilepticus.

    Ascoli, Michele / Ferlazzo, Edoardo / Gasparini, Sara / Mastroianni, Giovanni / Citraro, Rita / Roberti, Roberta / Russo, Emilio

    International journal of general medicine

    2021  Volume 14, Page(s) 2965–2973

    Abstract: Status epilepticus (SE) is a neurological and medical emergency, defined as a condition resulting either from the failure of the mechanisms responsible of seizure self-limitation or from the initiation of mechanisms which lead to atypically prolonged ... ...

    Abstract Status epilepticus (SE) is a neurological and medical emergency, defined as a condition resulting either from the failure of the mechanisms responsible of seizure self-limitation or from the initiation of mechanisms which lead to atypically prolonged seizures. Further than death, SE can have long-term consequences, including neuronal injury, depending on the type, cause and duration of seizures with severe associated disabilities. In Europe, SE shows an incidence rate ranging about 9 to 40/100,000/y. In adults, mortality of patients with SE is ~30%, and even higher (up to 40%) in refractory status epilepticus. To date, etiology, duration, presence of comorbidity, level of consciousness, semiology and age are the main clinical predictors of SE outcome.
    Language English
    Publishing date 2021-06-28
    Publishing country New Zealand
    Document type Journal Article ; Review
    ZDB-ID 2452220-X
    ISSN 1178-7074
    ISSN 1178-7074
    DOI 10.2147/IJGM.S295855
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: De novo myoclonic status epilepticus in Alzheimer disease.

    Pascarella, Angelo / Cianci, Vittoria / Manzo, Lucia / Neri, Sabrina / Gasparini, Sara / Santangelo, Domenico / Ferlazzo, Edoardo / Aguglia, Umberto

    Seizure

    2022  Volume 97, Page(s) 35–36

    MeSH term(s) Alzheimer Disease/complications ; Electroencephalography ; Epilepsies, Myoclonic ; Humans ; Status Epilepticus/complications
    Language English
    Publishing date 2022-03-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 1137610-7
    ISSN 1532-2688 ; 1059-1311
    ISSN (online) 1532-2688
    ISSN 1059-1311
    DOI 10.1016/j.seizure.2022.03.005
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    Zs.A 3573: Show issues Location:
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