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  1. Book ; Online: Chapter La componente romanza del lessico ucraino

    Del Gaudio, Salvatore

    (Biblioteca di Studi Slavistici)

    2019  

    Series title Biblioteca di Studi Slavistici
    Keywords Sociology ; lexicology ; loan-words ; Ukrainian ; Romance languages ; East Slavic languages
    Language 0|i
    Size 1 electronic resource (10 pages)
    Publisher Firenze University Press
    Publishing place Florence
    Document type Book ; Online
    Note Italian ; Open Access
    HBZ-ID HT021616523
    ISBN 9788864539102 ; 8864539107
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Book ; Online: Chapter Between Three Languages, Dialects and Forms of Mixed Speech: Dialect and Language Contacts in Ukrainian-Belarusian Transitional Area

    DEL GAUDIO, Salvatore

    (Biblioteca di Studi Slavistici)

    2018  

    Series title Biblioteca di Studi Slavistici
    Keywords Ukrainian-Belarusian Transitional Dialects ; Dialect / Language Contact ; East Slavic Dialectology ; Sociolinguistics
    Language 0|e
    Size 1 electronic resource (15 pages)
    Publisher Firenze University Press
    Publishing place Florence
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT021614501
    ISBN 9788864537238 ; 8864537236
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  3. Article ; Online: Phonological working memory is adversely affected in adults with anorexia nervosa: a systematic literature review.

    Dahlén, Amelia D / Gaudio, Santino / Schiöth, Helgi B / Brooks, Samantha J

    Eating and weight disorders : EWD

    2022  Volume 27, Issue 6, Page(s) 1931–1952

    Abstract: Purpose: Cognitive restraint has potentiating and deleterious effects on working memory (WM) in anorexia nervosa (AN). Conflicting evidence may be due to heterogeneity of tasks examining different WM components (e.g., verbal/auditory versus visuospatial) ...

    Abstract Purpose: Cognitive restraint has potentiating and deleterious effects on working memory (WM) in anorexia nervosa (AN). Conflicting evidence may be due to heterogeneity of tasks examining different WM components (e.g., verbal/auditory versus visuospatial), and differences in adolescent versus adult AN. Additionally, differential cognitive profiles of restricting versus binge/purging subtypes, comorbid psychiatric disorders and psychotropic medication use may confound findings.
    Methods: To address these conflicts, 25 studies, published between 2016 and 2021, investigating WM in children, adolescents and adults with AN were systematically reviewed using PRISMA guidelines.
    Results: In 71% of WM tasks, no difference in performance between AN patients and age-matched controls was reported, while 29% of WM tasks showed worse performance. Adults with AN displayed deficits in 44% of the verbal/auditory tasks, while performance remained unaffected in 86% of visuospatial tasks.
    Conclusion: Examining age groups and WM subsystems separately revealed novel findings of differentially affected WM components in AN. Comorbidities and psychotropic medications were common among AN participants and should be regarded as critical confounding factors for WM measures. Future studies examining different components of WM, acknowledging these confounding factors, may reveal specific deficits in AN to aid treatment improvement strategies.
    Level of evidence: I, systematic review.
    MeSH term(s) Adolescent ; Adult ; Anorexia Nervosa/complications ; Child ; Comorbidity ; Feeding and Eating Disorders ; Humans ; Memory, Short-Term ; Neuropsychological Tests
    Language English
    Publishing date 2022-02-08
    Publishing country Germany
    Document type Journal Article ; Review ; Systematic Review
    ZDB-ID 2038625-4
    ISSN 1590-1262 ; 1124-4909
    ISSN (online) 1590-1262
    ISSN 1124-4909
    DOI 10.1007/s40519-022-01370-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression: A UK Biobank study.

    Gaudio, Santino / Rukh, Gull / Di Ciommo, Vincenzo / Berkins, Samuel / Wiemerslage, Lyle / Schiöth, Helgi B

    NeuroImage

    2023  Volume 283, Page(s) 120438

    Abstract: The benefits of consuming fruits and vegetables are widely accepted. While previous studies suggest a protective role of fruits and vegetables against a variety of diseases such as dementia and depression, the biological mechanisms/effects remain unclear. ...

    Abstract The benefits of consuming fruits and vegetables are widely accepted. While previous studies suggest a protective role of fruits and vegetables against a variety of diseases such as dementia and depression, the biological mechanisms/effects remain unclear. Here we investigated the effect of fruit and vegetable consumption on brain structure. Particularly on grey matter (GM) and white matter (WM) volumes, regional GM volumes and subcortical volumes. Cross-sectional imaging data from UK Biobank cohort was used. A total of 9925 participants (Mean age 62.4 ± 7.5 years, 51.1 % men) were included in the present analysis. Measures included fruit and vegetable intake, other dietary patterns and a number of selected lifestyle factors and clinical data. Brain volumes were derived from structural brain magnetic resonance imaging. General linear model was used to study the associations between brain volumes and fruit/vegetable intakes. After adjusting for selected confounding factors, salad/raw vegetable intake showed a positive association with total white matter volume, fresh fruit intake showed a negative association with total grey matter (GM) volume. Regional GM analyses showed that higher fresh fruit intake was associated with larger GM volume in the left hippocampus, right temporal occipital fusiform cortex, left postcentral gyrus, right precentral gyrus, and right juxtapositional lobule cortex. We conclude that fruit and vegetable consumption seems to specifically modulate brain volumes. In particular, fresh fruit intake may have a protective role in specific cortical areas such as the hippocampus, areas robustly involved in the pathophysiology of dementia and depression.
    MeSH term(s) Male ; Humans ; Middle Aged ; Aged ; Female ; Gray Matter/diagnostic imaging ; Gray Matter/pathology ; Fruit ; Depression/diagnostic imaging ; Biological Specimen Banks ; White Matter/diagnostic imaging ; White Matter/pathology ; Magnetic Resonance Imaging/methods ; United Kingdom ; Dementia/diagnostic imaging ; Dementia/pathology
    Language English
    Publishing date 2023-10-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1147767-2
    ISSN 1095-9572 ; 1053-8119
    ISSN (online) 1095-9572
    ISSN 1053-8119
    DOI 10.1016/j.neuroimage.2023.120438
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Personality and eating and weight disorders: an open research challenge.

    Gaudio, Santino / Dakanalis, Antonios

    Eating and weight disorders : EWD

    2017  Volume 23, Issue 2, Page(s) 143–147

    MeSH term(s) Eating/psychology ; Feeding Behavior/psychology ; Feeding and Eating Disorders/complications ; Feeding and Eating Disorders/psychology ; Humans ; Personality ; Personality Disorders/complications ; Personality Disorders/psychology
    Language English
    Publishing date 2017-11-24
    Publishing country Germany
    Document type Editorial
    ZDB-ID 2038625-4
    ISSN 1590-1262 ; 1124-4909
    ISSN (online) 1590-1262
    ISSN 1124-4909
    DOI 10.1007/s40519-017-0463-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Locked to a wrong body: Eating disorders as the outcome of a primary disturbance in multisensory body integration.

    Riva, Giuseppe / Gaudio, Santino

    Consciousness and cognition

    2017  Volume 59, Page(s) 57–59

    Abstract: In his recent paper "Distorted body representations in anorexia nervosa" Gadsby (2017) discussed empirical evidence regarding anorexic patients' distorted body representations. In particular, he interpreted them using the O'Shaughnessy's long-term body ... ...

    Abstract In his recent paper "Distorted body representations in anorexia nervosa" Gadsby (2017) discussed empirical evidence regarding anorexic patients' distorted body representations. In particular, he interpreted them using the O'Shaughnessy's long-term body image (LTB) hypothesis (O'Shaughnessy, 1998): individuals with anorexia nervosa (AN) have a distorted LTB that tracks changes in the spatial content of the body and supplies this distorted content to other body representations. Even if we agree on the involvement of body memory in the distorted body representation, an open issue not fully addressed in the paper is: why AN patients do not update their LTBs to reflect their true dimensions? Our correspondence tries to answer to this question using a new neuropsychological and neurobiological theory: the Allocentric Lock Theory - ALT.
    MeSH term(s) Adult ; Attention/physiology ; Awareness/physiology ; Consciousness/physiology ; Female ; Humans ; Male ; Psychomotor Performance/physiology ; Unconscious (Psychology) ; Visual Perception/physiology ; Young Adult
    Language English
    Publishing date 2017-08-31
    Publishing country United States
    Document type Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 1106647-7
    ISSN 1090-2376 ; 1053-8100
    ISSN (online) 1090-2376
    ISSN 1053-8100
    DOI 10.1016/j.concog.2017.08.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: What about the assessment of personality disturbance in adolescents with eating disorders?

    Gaudio, Santino / Dakanalis, Antonios

    Eating and weight disorders : EWD

    2017  Volume 22, Issue 3, Page(s) 551–552

    MeSH term(s) Adolescent ; Comorbidity ; Feeding and Eating Disorders ; Humans ; Personality ; Personality Disorders/epidemiology
    Language English
    Publishing date 2017-02-20
    Publishing country Germany
    Document type Letter ; Comment
    ZDB-ID 2038625-4
    ISSN 1590-1262 ; 1124-4909
    ISSN (online) 1590-1262
    ISSN 1124-4909
    DOI 10.1007/s40519-017-0368-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Perspectives of data science in preclinical safety assessment.

    Steger-Hartmann, Thomas / Kreuchwig, Annika / Wang, Ken / Birzele, Fabian / Draganov, Dragomir / Gaudio, Stefano / Rothfuss, Andreas

    Drug discovery today

    2023  Volume 28, Issue 8, Page(s) 103642

    Abstract: The data landscape in preclinical safety assessment is fundamentally changing because of not only emerging new data types, such as human systems biology, or real-world data (RWD) from clinical trials, but also technological advancements in data- ... ...

    Abstract The data landscape in preclinical safety assessment is fundamentally changing because of not only emerging new data types, such as human systems biology, or real-world data (RWD) from clinical trials, but also technological advancements in data-processing software and analytical tools based on deep learning approaches. The recent developments of data science are illustrated with use cases for the three factors: predictive safety (new in silico tools), insight generation (new data for outstanding questions); and reverse translation (extrapolating from clinical experience to resolve preclinical questions). Further advances in this field can be expected if companies focus on overcoming identified challenges related to a lack of platforms and data silos and assuring appropriate training of data scientists within the preclinical safety teams.
    MeSH term(s) Humans ; Data Science ; Software ; Systems Biology
    Language English
    Publishing date 2023-05-26
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 1324988-5
    ISSN 1878-5832 ; 1359-6446
    ISSN (online) 1878-5832
    ISSN 1359-6446
    DOI 10.1016/j.drudis.2023.103642
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Brain and Cognitive Development in Adolescents with Anorexia Nervosa: A Systematic Review of fMRI Studies.

    Olivo, Gaia / Gaudio, Santino / Schiöth, Helgi B

    Nutrients

    2019  Volume 11, Issue 8

    Abstract: Anorexia nervosa (AN) is an eating disorder often occurring in adolescence. AN has one of the highest mortality rates amongst psychiatric illnesses and is associated with medical complications and high risk for psychiatric comorbidities, persisting after ...

    Abstract Anorexia nervosa (AN) is an eating disorder often occurring in adolescence. AN has one of the highest mortality rates amongst psychiatric illnesses and is associated with medical complications and high risk for psychiatric comorbidities, persisting after treatment. Remission rates range from 23% to 33%. Moreover, weight recovery does not necessarily reflect cognitive recovery. This issue is of particular interest in adolescence, characterized by progressive changes in brain structure and functional circuitries, and fast cognitive development. We reviewed existing literature on fMRI studies in adolescents diagnosed with AN, following PRISMA guidelines. Eligible studies had to: (1) be written in English; (2) include only adolescent participants; and (3) use block-design fMRI. We propose a pathogenic model based on normal and AN-related neural and cognitive maturation during adolescence. We propose that underweight and delayed puberty-caused by genetic, environmental, and neurobehavioral factors-can affect brain and cognitive development and lead to impaired cognitive flexibility, which in turn sustains the perpetuation of aberrant behaviors in a vicious cycle. Moreover, greater punishment sensitivity causes a shift toward punishment-based learning, leading to greater anxiety and ultimately to excessive reappraisal over emotions. Treatments combining physiological and neurobehavioral rationales must be adopted to improve outcomes and prevent relapses.
    MeSH term(s) Adolescent ; Adolescent Behavior ; Adolescent Development ; Age Factors ; Anorexia Nervosa/diagnostic imaging ; Anorexia Nervosa/physiopathology ; Anorexia Nervosa/psychology ; Anorexia Nervosa/therapy ; Brain/diagnostic imaging ; Brain/growth & development ; Cognition ; Cognition Disorders/diagnostic imaging ; Cognition Disorders/physiopathology ; Cognition Disorders/psychology ; Feeding Behavior ; Female ; Humans ; Magnetic Resonance Imaging ; Mental Health ; Puberty, Delayed/physiopathology ; Puberty, Delayed/psychology ; Recovery of Function ; Risk Factors ; Sex Factors ; Treatment Outcome
    Language English
    Publishing date 2019-08-15
    Publishing country Switzerland
    Document type Journal Article ; Systematic Review
    ZDB-ID 2518386-2
    ISSN 2072-6643 ; 2072-6643
    ISSN (online) 2072-6643
    ISSN 2072-6643
    DOI 10.3390/nu11081907
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Relation Between Near‐Fault Ground Motion Impulsive Signals and Source Parameters

    Scala, A. / Festa, G. / Del Gaudio, S.

    Journal of geophysical research. 2018 Sept., v. 123, no. 9

    2018  

    Abstract: Near‐fault ground motion records often present impulsive signals, characterized by a large amplitude in the velocity wavefield and by the energy concentrated in a short time window as compared to the total earthquake duration. This pulse‐like behavior is ...

    Abstract Near‐fault ground motion records often present impulsive signals, characterized by a large amplitude in the velocity wavefield and by the energy concentrated in a short time window as compared to the total earthquake duration. This pulse‐like behavior is ascribed to the directivity of the seismic rupture, and it requires a stronger demand to the buildings not predicted by the classical design spectra. In this work we investigate the pulse occurrence and duration in near‐fault synthetic seismograms generated from an ensemble of k⁻² source models. We exploited the fault geometry of the Mw = 6.3, 2009 L'Aquila earthquake, which represents a typical example of normal‐fault earthquake for which several records in the fault vicinity are available for comparison with synthetics. We show that impulsive records are sensitive to the rupture velocity, to the hypocenter depth, and to the station location, whether it is on the hanging wall or on the footwall. The pulse duration was also shown to be proportional to the risetime, and it scales with the source‐receiver distance and inversely with the rupture velocity. We model these results as an effect of the coupled along‐strike and updip directivity.
    Keywords earthquakes ; energy ; geometry ; geophysics ; research ; synthetic products
    Language English
    Dates of publication 2018-09
    Size p. 7707-7721.
    Publishing place John Wiley & Sons, Ltd
    Document type Article
    Note JOURNAL ARTICLE
    ISSN 2169-9313
    DOI 10.1029/2018JB015635
    Database NAL-Catalogue (AGRICOLA)

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