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Article ; Online: Influence of Covid 19 pandemic on intercultural communication and dialogue

Gaurav Sharma

E3S Web of Conferences, Vol 371, p

2023 Volume 05060

Abstract: Researchers researching the theme of intercultural communication and dialogue must re-examine a lot of objectives for the re-enlightenment of intercultural relations due to the impact of Covid 19 pandemic, which has distressed human interaction and ... ...

Abstract	Researchers researching the theme of intercultural communication and dialogue must re-examine a lot of objectives for the re-enlightenment of intercultural relations due to the impact of Covid 19 pandemic, which has distressed human interaction and social cultural contexts. This research focuses on the concept of intercultural communication and dialogue and its connectivity to humans internationally. This Paper reveals the complication of physical contact, impact of the pandemic, human suffering, hybrid education, social disruption, and social inequality. This Paper also brings SWOT analysis which unfolds weaknesses and threats to work on, with the help of strengths and opportunities. This paper also addresses the impact of intercultural communication and dialogues in the area of values, beliefs, conflict, stereotypes, languages, verbal and non-verbal communication, spoken and written language, relationships and interactions between people and society. This paper also highlights the influence of digitalization on society globally during the Covid-19 pandemic. All areas are specifically addressed to overcome all challenges mentioned in this paper for understanding the dimensions of cross-cultural cooperation and communication.
Keywords	Environmental sciences ; GE1-350
Subject code	306
Language	English
Publishing date	2023-01-01T00:00:00Z
Publisher	EDP Sciences
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Case Report

Sachin Gautam / Gaurav Sharma / Sumeet Singla / Sandeep Garg

Frontiers in Medicine, Vol

Secondary Hemophagocytic Lymphohistiocytosis (sHLH) and Candida auris Fungemia in Post-acute COVID-19 Syndrome: A Clinical Challenge

2022 Volume 9

Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes a disease (COVID-19) with multisystem involvement. The world is now entering a phase of post-COVID-19 manifestations in this pandemic. Secondary hemophagocytic ... ...

Abstract	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes a disease (COVID-19) with multisystem involvement. The world is now entering a phase of post-COVID-19 manifestations in this pandemic. Secondary hemophagocytic lymphohistiocytosis (sHLH) is a life-threatening hyperinflammatory event triggered by viral infections, including SARS-CoV-2. Both Multisystem Inflammatory Syndrome-Adults (MIS-A) and Cytokine Storm Syndrome (CSS) are considered close differentials of sHLH and add to the spectrum of Post-acute COVID-19 syndrome (PACS). In this report, we presented the case of a middle-aged Asian man who was initially discharged upon recovery from severe COVID-19 infection after 17 days of hospitalization to a private institute and later came to our hospital 13 days post-discharge. Here, he was diagnosed with sHLH, occurring as an extension of CSS, with delayed presentation falling within the spectrum of PACS. The diagnosis of sHLH was made holistically with the HLH-2004 criteria. Our patient initially responded to intravenous immunoglobulin (IVIG) and dexamethasone, later complicated by disseminated Candida auris infection and had a fatal outcome. Though many cases of HLH during active COVID-19 and a few cases post COVID-19 recovery have been reported, based on H-score, which has limitations as a diagnostic tool. We report the first case report of post-COVID-19 sHLH using the HLH-2004 criteria, complicated by disseminated Candidemia, emphasizing that the care of patients with COVID-19 does not conclude at the time of hospital discharge. We highlight the importance of surveillance in the post-COVID phase for early detection of sHLH which may predispose to fatal opportunistic infections (OIs).
Keywords	post acute covid-19 syndrome (PACS) ; secondary hemophagocytic lymphohistiocytosis ; Candida auris ; macrophage activation syndrome (MAS) ; intravenous immunoglobulin ; cytokine storm syndrome (CSS) ; Medicine (General) ; R5-920
Subject code	610
Language	English
Publishing date	2022-06-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Are Countries Becoming Better at SARS-CoV-2 Genomic Surveillance?

Utkarsha Mahanta / Gayatri Saberwal / Gaurav Sharma

Frontiers in Public Health, Vol

2022 Volume 10

Keywords	genome surveillance ; SARS-CoV-2 ; public health ; genome sequencing ; GISAID ; Public aspects of medicine ; RA1-1270
Language	English
Publishing date	2022-04-01T00:00:00Z
Publisher	Frontiers Media S.A.
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Performability evaluation, validation and optimization for the steam generation system of a coal-fired thermal power plant

Subhash Malik / Shubham Verma / Arun Gupta / Gaurav Sharma / Shakuntla Singla

MethodsX, Vol 9, Iss , Pp 101852- (2022)

2022

Abstract: The present paper talks over performability evaluation for a steam generation system of a Coal Fired Thermal Power Plant (CFTPP) using the concept of the Markov method. A steam generation system provides a suitable amount of steam for the sound ... ...

Abstract	The present paper talks over performability evaluation for a steam generation system of a Coal Fired Thermal Power Plant (CFTPP) using the concept of the Markov method. A steam generation system provides a suitable amount of steam for the sound functioning of the plant. The system comprises five subsystems, i.e., High-Pressure Heater, Economizer, Boiler Drum, Water Tubes, and Super Heater. First, the transition diagram of the concerned system is designed based on the state probabilities of various subsystems. The differential equations are derived based on the mnemonic rule. After that, the performability model is developed by using the normalizing condition. The performability levels for various subsystems are obtained by placing the appropriate value of failure and repair rates in the developed model. The performability of each subsystem is evaluated based on performability matrices. It is observed that the economizer subsystem is most critical in which the availability increased from 0.7640 to 0.8827, i.e. (11.87 %). In contrast, boiler drum is the least crucial subsystem with availability enhanced from 0.8627 to 0.8657 (i.e., 0.3 %). The results show that the economizer subsystem must be given top priority, and the boiler drum be given the least priority from the maintenance outlook. The performability levels obtained through the Markov method are compared with those obtained through the Artificial Neural Network to validate. Moreover, machine learning (artificial neural network) and optimization technique (particle swarm optimization) is also employed to check the adequacy of the results and optimized process parameters. • The aim of the present study is evaluate the performance of steam generation system of a coal fired thermal power plant. • The probabilistic approach (i.e. Makov Method) is used to formulate the transition diagram of the steam generation system. Then, the first-order differential equations are obtained using the mnemonic rule and further solved recursively. • The results show that the ...
Keywords	Markov method ; Mnemonic rule ; Normalizing condition ; Performability model ; Artificial neural network ; Particle swarm optimization ; Science ; Q
Subject code	620
Language	English
Publishing date	2022-01-01T00:00:00Z
Publisher	Elsevier
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Rare Earth Doped ZnO Nanoparticles as Spintronics and Photo Catalyst for Degradation of Pollutants

Pooja Dhiman / Garima Rana / Amit Kumar / Elmuez A. Dawi / Gaurav Sharma

Molecules, Vol 28, Iss 2838, p

2023 Volume 2838

Abstract: Antibiotic water contamination is a growing environmental problem in the present day. As a result, water treatment is required for its reduction and elimination. Due to their important role in resolving this issue, photocatalysts have drawn a great deal ... ...

Abstract	Antibiotic water contamination is a growing environmental problem in the present day. As a result, water treatment is required for its reduction and elimination. Due to their important role in resolving this issue, photocatalysts have drawn a great deal of interest over the past few decades. When non-biodegradable organic matter is present in polluted water, the photo catalytic process, which is both environmentally friendly and an improved oxidation method, can be an effective means of remediation. In this regard, we report the successful synthesis of pure phased rare earth doped ZnO nanoparticles for tetracycline degradation. The prepared catalysts were systematically characterized for structural, optical, and magnetic properties. The optical band gap was tailored by rare earth doping, with redshift for Sm and Dy doped nanoparticles and blueshift for Nd doped ZnO nanoparticles. The analysis of photoluminescence spectra revealed information about the defect chemistry of all synthesised nanoparticles. Magnetic studies revealed that all synthesized diluted magnetic semiconductors exhibit room temperature ferromagnetism and can be employed for spintronic applications. Moreover, Dy doped ZnO nanoparticles were found to exhibit a maximum degradation efficiency of 74.19% for tetracycline (TCN) removal. The synthesized catalysts were also employed for the degradation of Malachite green (MG), and Crystal violet (CV) dyes. The maximum degradation efficiency achieved was 97.18% for MG and 98% for CV for Dy doped ZnO nanoparticles. The degradation mechanism involved has been discussed in view of the reactive species determined from scavenging experiments.
Keywords	ZnO ; photocatalysis ; tetracycline ; chemical water pollutants ; nanomaterials ; Organic chemistry ; QD241-441
Subject code	620
Language	English
Publishing date	2023-03-01T00:00:00Z
Publisher	MDPI AG
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Opportunities and challenges for developing closed-loop bioelectronic medicines

Patrick D Ganzer / Gaurav Sharma

Neural Regeneration Research, Vol 14, Iss 1, Pp 46-

2019 Volume 50

Abstract: The peripheral nervous system plays a major role in the maintenance of our physiology. Several peripheral nerves intimately regulate the state of the brain, spinal cord, and visceral systems. A new class of therapeutics, called bioelectronic medicines, ... ...

Abstract	The peripheral nervous system plays a major role in the maintenance of our physiology. Several peripheral nerves intimately regulate the state of the brain, spinal cord, and visceral systems. A new class of therapeutics, called bioelectronic medicines, are being developed to precisely regulate physiology and treat dysfunction using peripheral nerve stimulation. In this review, we first discuss new work using closed-loop bioelectronic medicine to treat upper limb paralysis. In contrast to open-loop bioelectronic medicines, closed-loop approaches trigger ‘on demand’ peripheral nerve stimulation due to a change in function (e.g., during an upper limb movement or a change in cardiopulmonary state). We also outline our perspective on timing rules for closed-loop bioelectronic stimulation, interface features for non-invasively stimulating peripheral nerves, and machine learning algorithms to recognize disease events for closed-loop stimulation control. Although there will be several challenges for this emerging field, we look forward to future bioelectronic medicines that can autonomously sense changes in the body, to provide closed-loop peripheral nerve stimulation and treat disease.
Keywords	spinal cord injury ; stroke ; plasticity ; closed-loop ; bioelectronic medicine ; machine learning ; nerve stimulation ; vagus nerve ; Neurology. Diseases of the nervous system ; RC346-429
Subject code	629
Language	English
Publishing date	2019-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Mycobacterium lepromatosis Lepromatous Leprosy in US Citizen Who Traveled to Disease-Endemic Areas

Gaurav Sharma / Vishnu Dutt Sharma

Emerging Infectious Diseases, Vol 25, Iss 2, Pp 389-

2019 Volume 390

Keywords	Mycobacterium lepromatosis ; leprosy ; travel-related hazard ; host susceptibility ; United States ; bacteria ; Medicine ; R ; Infectious and parasitic diseases ; RC109-216
Language	English
Publishing date	2019-02-01T00:00:00Z
Publisher	Centers for Disease Control and Prevention
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Comparison of contrasts in rainfall and drought characteristics in the Chambal basin in Madhya Pradesh and Rajasthan

Gaurav Sharma / T. Thomas / R. M. Singh

Journal of Water and Climate Change, Vol 12, Iss 8, Pp 3932-

2021 Volume 3957

Abstract: The availability of water resources is under stress due to its unsustainable exploitation. The Chambal basin is located in the water-scarce region in India with average annual rainfall varying between 687.1 mm in the Rajasthan (RJ) region and 938.2 mm in ...

Abstract	The availability of water resources is under stress due to its unsustainable exploitation. The Chambal basin is located in the water-scarce region in India with average annual rainfall varying between 687.1 mm in the Rajasthan (RJ) region and 938.2 mm in the Madhya Pradesh (MP) region. On average, there are 48 rainy days in the MP region and 39 rainy days in the RJ region of the Chambal basin. Fourteen drought years have been identified during the period spanning 34 years (1985–2018). 44% of basin area located in the MP region and 54% of basin area located in the RJ are found to be drought-prone. The Standardized Precipitation Index-based evaluation of drought characteristics indicated higher drought frequency in the RJ region varying between 1 in 3 years and 1 in 4 years and between 1 in 3 years and 1 in 5 years in the MP region, which has also been substantiated by the Relative Departure Index (RDI), namely average RDI for RJ (0.69) and MP (0.58). The understanding of the contrasts in rainfall and drought characteristics in upper reaches (MP region) and lower reaches (RJ region) of the Chambal basin will help in holistic management and sharing of water resources based on these contrasts and constraints. HIGHLIGHTS Drought indicator-based investigation of drought characteristics in a major tributary of the Ganga river system.; Evaluation of the contrasts in the two different regions (Madhya Pradesh and Rajasthan) of the Chambal basin.; Standardized Precipitation Index-based evaluation of meteorological droughts.; Prioritization of drought-prone districts for effecting mitigation activities during periods of drought.;
Keywords	chambal ; drought ; mann–kendall test ; relative departure index ; sen's slope ; standardized precipitation index ; Environmental technology. Sanitary engineering ; TD1-1066 ; Environmental sciences ; GE1-350
Subject code	910
Language	English
Publishing date	2021-12-01T00:00:00Z
Publisher	IWA Publishing
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Evaluation of polyherbal formulation for antihypertensive activity in albino rats

Pratibha / Gaurav Sharma / Sudipta Kumar Rath

Journal of Ayurveda, Vol 15, Iss 3, Pp 155-

2021 Volume 162

Abstract: Background: Hypertension (HTN) is a multifactorial clinical condition and therefore can be managed in multiple pathways. Long time period use of modern antihypertensive drugs is associated with a spectrum of toxic and side effects. Modern ... ...

Abstract	Background: Hypertension (HTN) is a multifactorial clinical condition and therefore can be managed in multiple pathways. Long time period use of modern antihypertensive drugs is associated with a spectrum of toxic and side effects. Modern antihypertensive drugs are not ideally effective owing to dependence, side effects, and cost. However, therapeutic interventions using herbal drugs for HTN have gained widespread attention worldwide. Aim: The aim of the study is to evaluate the antihypertensive activity of polyherbal formulation (NIA/DG/2015/01) as an adjuvant with modern antihypertensive drug or as a stand-alone drug in cadmium chloride (CdCl2)-induced hypertensive albino rat model. Methods: The polyherbal formulation (NIA/DG/2015/01) comprises the bark of Terminalia arjuna (Roxb.) W and A, the root of Withania somnifera (Linn.), the rhizome of Nardostachys jatamansi DC., the root of Boerhaavia diffusa (Linn.), and whole plant of Convolvulus pluricaulis Choisy. All the herbs were separately extracted in aqueous medium. Polyherbal formulation (90 mg/kg., p.o.), was evaluated using the CdCl2-induced hypertensive rat model using the Verapamil as a standard reference drug. HTN was induced in albino rats by intraperitoneal administration of CdCl2 (0.1% CdCl2 solution) 1 mg/kg/day for 15 days. After 15 days, intervention was started for 28 days, and blood pressure (B.P.) was measured in every 7th day. Results: Polyherbal formulation significantly reduced (P < 0.001, one-way analysis of variance followed by Tukey's multiple comparison test and Dunnett's multiple comparison test) systolic and diastolic B.P. in CdCl2-induced HTN model when compared with Verapamil. Conclusion: Polyherbal formulation (NIA/DG/2015/01) possesses significant antihypertensive activity.
Keywords	antihypertensive ; boerhaavia diffusa ; cadmium chloride ; convolvulus pluricaulis ; hypertension ; polyherbal ; terminalia arjuna ; withania somnifera ; Other systems of medicine ; RZ201-999
Subject code	630
Language	English
Publishing date	2021-01-01T00:00:00Z
Publisher	Wolters Kluwer Medknow Publications
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Immunohistochemical Characterisation of Cell of Origin in Diffuse Large B-cell Lymphoma and its Association with the Double Expressor Phenotype

Prachi / Hemamalini Aiyer / Gaurav Sharma / Suparno Chakrabarti / Sarita Rani Jaiswal

Journal of Clinical and Diagnostic Research, Vol 16, Iss 5, Pp EC15-EC

A Retrospective Study

2022 Volume 18

Abstract: Introduction: Diffuse Large B-cell Lymphoma (DLBCL) is the most common type of Non-Hodgkin Lymphoma (NHL) and is categorised into the Germinal Centre B-cell (GCB) and Activated B-cell (ABC/Non GCB) subtypes as per the Cell Of Origin (COO) model with the ... ...

Abstract	Introduction: Diffuse Large B-cell Lymphoma (DLBCL) is the most common type of Non-Hodgkin Lymphoma (NHL) and is categorised into the Germinal Centre B-cell (GCB) and Activated B-cell (ABC/Non GCB) subtypes as per the Cell Of Origin (COO) model with the help of gene expression profiling/immunohistochemistry. The non GCB subtype has been found to associate with the Double Expressor (DE) phenotype (i.e., co-expression of BCL-2 and c-myc by IHC and this association was substantiated and proven to be statistically significant in the present study. Aim: To categorise all DLBCL cases into GCB and Non GCB and further into DE and Non-DE by using Hans and Choi IHC alogrithm. Materials and Methods: A retrospective study of 50 patients was carried out with the help of archival material filed in the Department of Anatomic Pathology at Dharamshila Narayana Superspeciality Hospital, New Delhi, India from 1st January 2019 to 30th June 2020. The study was approved by Instituitional Ethics Committee (IEC). The study cohort was divided into two groups- group A with nodal presentation and group B with extranodal presentation. By using the Hans and Choi IHC algorithms, the cases were categorised into the GCB and non GCB subtypes in both the groups. Chi-square test and Yates correction were used for statistical analysis. Results: The median age at presentation was 49 years (20-81 years) with a male to female ratio of 2.3:1 (35 males and 15 females). Group A with nodal disease included 28 patients and group B with extranodal disease included 22 patients. The DE phenotype was determined in each case by the co-expression of c-myc (>40%) and BCL-2 (>50%) by IHC. By using the statistical chi-square test analysis and Yates correction, the association of DE was found to be statistically significant with non GCB type lymphomas and non DE with GCB lymphomas with p-value being 0.0005 and 0.00168, respectively. Conclusion: Due to the heterogeneity inherent in DLBCL, prediction of the DE phenotype and the COO by IHC is a sensitive tool ...
Keywords	cell of origin model ; hans and choi algorithm ; immunohistochemistry ; Medicine ; R
Subject code	610
Language	English
Publishing date	2022-05-01T00:00:00Z
Publisher	JCDR Research and Publications Private Limited
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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