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  1. Article ; Online: La Valentine disease: An outbreak of exanthematic typhus in Marseille, France, in 1810.

    Gautret, Philippe

    The journal of the Royal College of Physicians of Edinburgh

    2023  Volume 53, Issue 4, Page(s) 290–294

    Abstract: Background: Exanthematic typhus was highly frequent in the early 19th century among military troops and prisoners and at hospitals.: Methods: Based on old reports, we describe an outbreak in a village, in Southern France, in 1810.: Results: Twenty- ...

    Abstract Background: Exanthematic typhus was highly frequent in the early 19th century among military troops and prisoners and at hospitals.
    Methods: Based on old reports, we describe an outbreak in a village, in Southern France, in 1810.
    Results: Twenty-eight cases were identified, over a period of 10 days following the death of the index case, in a soldier. Symptoms included notably persistent constant fever, myalgia and headaches, gastro-intestinal symptoms, prostration and stupor. Three patients suffered delirium and nine died (31.0%). Overall, symptoms persisted for 13-14 days. A total of 16 cases were secondary to contacts with the index case, and 10 cases were in house-hold contacts of secondary cases. Five familial clusters were described.
    Conclusion: This data suggest that exanthematic typhus outbreaks among civilian populations also occurred outside the context of hospitals, in link with introduction of the disease by prisoners or soldiers.
    MeSH term(s) Humans ; Typhus, Epidemic Louse-Borne/epidemiology ; Typhus, Epidemic Louse-Borne/history ; Disease Outbreaks ; Military Personnel ; Headache/epidemiology ; France/epidemiology
    Language English
    Publishing date 2023-11-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2866363-9
    ISSN 2042-8189 ; 0953-0932
    ISSN (online) 2042-8189
    ISSN 0953-0932
    DOI 10.1177/14782715231210333
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Decline in rabies cases in international travelers during the COVID-19 pandemic.

    Gautret, Philippe

    Travel medicine and infectious disease

    2023  Volume 54, Page(s) 102592

    MeSH term(s) Humans ; Rabies/epidemiology ; Rabies/prevention & control ; Pandemics ; COVID-19 ; Risk Assessment ; Travel ; Rabies Vaccines
    Chemical Substances Rabies Vaccines
    Language English
    Publishing date 2023-05-26
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2023.102592
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  3. Article ; Online: Influenza risk at Muslim pilgrimages in Iraq and Saudi Arabia.

    Gautret, Philippe

    Travel medicine and infectious disease

    2017  

    Language English
    Publishing date 2017-10-26
    Publishing country Netherlands
    Document type Editorial
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2017.10.016
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  4. Article ; Online: Travel-related respiratory symptoms and infections in travellers (2000-22): a systematic review and meta-analysis.

    Lovey, Thibault / Hasler, Robin / Gautret, Philippe / Schlagenhauf, Patricia

    Journal of travel medicine

    2023  Volume 30, Issue 5

    Abstract: Background: Respiratory tract infections (RTIs) are common in travellers due to the year-round or seasonal presence of respiratory pathogen and exposure to crowded environments during the itinerary. No study has systematically examined the burden of RTI ...

    Abstract Background: Respiratory tract infections (RTIs) are common in travellers due to the year-round or seasonal presence of respiratory pathogen and exposure to crowded environments during the itinerary. No study has systematically examined the burden of RTI infections among travellers. The aim of this systematic review and meta-analysis is to evaluate the prevalence of RTIs and symptoms suggestive of RTIs among travellers according to risk groups and/or geographic region, and to describe the spectrum of RTIs.
    Methods: The systematic review and meta-analysis was registered in PROSPERO (CRD42022311261). We searched Medline, Embase, Scopus, Cochrane Central, Web of Science, Science Direct and preprint servers MedRxiv, BioRxiv, SSRN and IEEE Xplore on 1 February 2022. Studies reporting RTIs or symptoms suggestive of RTIs in international travellers after 1 January 2000 were eligible. Data appraisal and extraction were performed by two authors, and proportional meta-analyses were used to obtain estimates of the prevalence of respiratory symptoms and RTIs in travellers and predefined risk groups.
    Findings: A total of 429 articles on travellers' illness were included. Included studies reported 86 841 symptoms suggestive of RTIs and 807 632 confirmed RTIs. Seventy-eight percent of reported respiratory symptoms and 60% of RTIs with available location data were acquired at mass gatherings events. Cough was the most common symptom suggestive of respiratory infections, and the upper respiratory tract was the most common site for RTIs in travellers. The prevalence of RTIs and respiratory symptoms suggestive of RTIs were 10% [8%; 14%] and 37% [27%; 48%], respectively, among travellers. Reporting of RTIs in travellers denoted by publication output was found to correlate with global waves of new respiratory infections.
    Interpretation: This study demonstrates a high burden of RTIs among travellers and indicates that travellers' RTIs reflect respiratory infection outbreaks. These findings have important implications for understanding and managing RTIs among travellers.
    MeSH term(s) Humans ; Travel ; Travel-Related Illness ; Respiratory Tract Infections/epidemiology ; Risk Factors ; Prevalence
    Language English
    Publishing date 2023-06-11
    Publishing country England
    Document type Meta-Analysis ; Systematic Review ; Journal Article
    ZDB-ID 1212504-0
    ISSN 1708-8305 ; 1195-1982
    ISSN (online) 1708-8305
    ISSN 1195-1982
    DOI 10.1093/jtm/taad081
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  5. Article ; Online: Multiple itchy lesions after recent travel.

    Eldin, Carole / Gautret, Philippe

    BMJ (Clinical research ed.)

    2021  Volume 372, Page(s) n231

    MeSH term(s) Adolescent ; Anthelmintics/therapeutic use ; Brazil ; Female ; France ; Humans ; Larva Migrans/diagnosis ; Larva Migrans/etiology ; Larva Migrans/therapy ; Pruritus/diagnosis ; Pruritus/etiology ; Pruritus/therapy ; Travel
    Chemical Substances Anthelmintics
    Language English
    Publishing date 2021-02-24
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj.n231
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  6. Article ; Online: Corrigendum to "Respiratory and gastrointestinal infections at the 2017 Grand Magal de Touba, Senegal: A prospective cohort survey" [Trav. Med. Infect. Dis. 32, November-December 2019, 101410].

    Hoang, Van Thuan / Gautret, Philippe

    Travel medicine and infectious disease

    2021  Volume 47, Page(s) 102100

    Language English
    Publishing date 2021-06-08
    Publishing country Netherlands
    Document type Published Erratum
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2021.102100
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  7. Article ; Online: Reply to Alizazgar J. Dangers of the use of hydroxychloroquine and azithromycin combination in COVID-19 patients.

    Honoré, Stéphane / Gautret, Philippe

    Travel medicine and infectious disease

    2021  Volume 40, Page(s) 101984

    MeSH term(s) Azithromycin/adverse effects ; COVID-19/drug therapy ; Drug Therapy, Combination ; Humans ; Hydroxychloroquine/adverse effects ; SARS-CoV-2
    Chemical Substances Hydroxychloroquine (4QWG6N8QKH) ; Azithromycin (83905-01-5)
    Language English
    Publishing date 2021-02-05
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2021.101984
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  8. Article ; Online: High Prevalence of Non-typeable Haemophilus influenzae and Haemophilus haemolyticus Among Vaccinated Children with Community-Acquired Pneumonia in Vietnam.

    Tran, Xuan Duong / Hoang, Van Thuan / Dao, Thi Loi / Marty, Pierre / Gautret, Philippe

    Journal of epidemiology and global health

    2024  

    Abstract: Among 467 children under five hospitalized with community-acquired pneumonia, the prevalence of Haemophilus influenzae or Haemophilus haemolyticus was 60.8%, all cases were non-typable H. influenzae (NTHi) or H. haemolyticus. NTHi/H. haemolyticus PCR ... ...

    Abstract Among 467 children under five hospitalized with community-acquired pneumonia, the prevalence of Haemophilus influenzae or Haemophilus haemolyticus was 60.8%, all cases were non-typable H. influenzae (NTHi) or H. haemolyticus. NTHi/H. haemolyticus PCR detection was associated with about twice the risk for severe disease. The results highlight the need for increased awareness and research efforts to investigate the role of NTHi/H. haemolyticus in severe CAP among children.
    Language English
    Publishing date 2024-02-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2645324-1
    ISSN 2210-6014 ; 2210-6014
    ISSN (online) 2210-6014
    ISSN 2210-6014
    DOI 10.1007/s44197-024-00195-8
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  9. Article ; Online: Occupational exposure to Coxiella burnetii during cardiac surgery: A case report and review of the literature.

    Diwunga, Patient / Million, Matthieu / Ravaux, Isabelle / Fournier, Pierre Edouard / Gautret, Philippe

    Acta microbiologica et immunologica Hungarica

    2024  Volume 71, Issue 1, Page(s) 76–81

    Abstract: We report a case of exposure to Coxiella burnetii in a surgical nurse who underwent an injury of her finger with a scalpel blade during a native aortic valve replacement with a bio-prosthetic cardiac valve conducted on a patient suffering from C. ... ...

    Abstract We report a case of exposure to Coxiella burnetii in a surgical nurse who underwent an injury of her finger with a scalpel blade during a native aortic valve replacement with a bio-prosthetic cardiac valve conducted on a patient suffering from C. burnetii aortic endocarditis. Given the positivity of C. burnetii culture and PCR from the patient's aortic valve, she was prescribed prophylactic doxycycline 100 mg twice a day for 10 days. Q fever is an occupational zoonosis resulting usually of exposure to infected animals by inhalation of infected aerosols or consumption of contaminated raw milk. Apart from materno-foetal transmission, about 180 cases of human-to-human C. burnetii transmission have been published from 1949 to today, including transmission by blood transfusion, sexual relations, transmission in the healthcare setting to staff, patient attendants and other patients that were likely infected from inhalation of aerosol from respiratory or placental products, transmission to staff during autopsies of patients with Q fever and transmission in familial settings. As C. burnetii is a highly infectious bacterium, that may cause infection with a low inoculum, it should be added to the list of organisms which may be of concern following blood exposure among healthcare professionals.
    MeSH term(s) Humans ; Animals ; Female ; Pregnancy ; Coxiella burnetii/genetics ; Q Fever/microbiology ; Placenta ; Cardiac Surgical Procedures ; Occupational Exposure
    Language English
    Publishing date 2024-03-11
    Publishing country Hungary
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 918256-1
    ISSN 1588-2640 ; 1217-8950
    ISSN (online) 1588-2640
    ISSN 1217-8950
    DOI 10.1556/030.2024.02240
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Pericarditis related to post-acute COVID infection: A case report and review of the literature.

    Nguyen, Nhu Ngoc / Dudouet, Pierre / Dhiver, Catherine / Gautret, Philippe

    Acta microbiologica et immunologica Hungarica

    2023  Volume 70, Issue 2, Page(s) 100–110

    Abstract: Cardiovascular involvement has been described in acute and recovered COVID-19 patients. Here, we present a case of symptomatic pericarditis with persistent symptoms for at least six months after the acute infection and report 66 published cases of ... ...

    Abstract Cardiovascular involvement has been described in acute and recovered COVID-19 patients. Here, we present a case of symptomatic pericarditis with persistent symptoms for at least six months after the acute infection and report 66 published cases of pericarditis in discharged COVID patients. Patient mean age ± SD was 49.7 ± 13.3 years, ranging from 15 to 75 years and 57.6% were female. A proportion of 89.4% patients reported at least one comorbidity, with autoimmune and allergic disorders, hypertension and dyslipidaemia, as the most frequent. Only 8.3% of patients experienced severe symptoms of acute COVID-19. The time between acute COVID and pericarditis symptoms varied from 14 to 255 days. Chest pain (90.9%), tachycardia (60.0%) and dyspnoea (38.2%) were the most frequent symptoms in post-acute pericarditis. A proportion of 45.5% and 87% of patients had an abnormal electrocardiogram and abnormal transthoracic ultrasound, respectively. Colchicine combined with non-steroidal anti-inflammatory drug (NSAID) or acetylsalicylic acid (aspirin) were prescribed to 39/54 (72%) patients. Of them, 12 were switched to corticosteroid therapy due to non-response to the first-line treatment. Only 6 patients had persisting symptoms and were considered as non-respondent to therapy.Our report highlights that pericarditis should be suspected in COVID-19 patients with persistent chest pain and dyspnoea when pulmonary function is normal. Treatment with non-steroidal anti-inflammatory and colchicine is usually effective but corticosteroids are sometimes required.
    MeSH term(s) Humans ; Female ; Male ; COVID-19/complications ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Pericarditis/diagnosis ; Pericarditis/drug therapy ; Pericarditis/etiology ; Aspirin/therapeutic use ; Colchicine/therapeutic use ; Chest Pain/complications ; Chest Pain/drug therapy
    Chemical Substances Anti-Inflammatory Agents, Non-Steroidal ; Aspirin (R16CO5Y76E) ; Colchicine (SML2Y3J35T)
    Language English
    Publishing date 2023-06-02
    Publishing country Hungary
    Document type Review ; Case Reports ; Journal Article
    ZDB-ID 918256-1
    ISSN 1588-2640 ; 1217-8950
    ISSN (online) 1588-2640
    ISSN 1217-8950
    DOI 10.1556/030.2023.02055
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