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  1. Article: Life support system using water electrolysis.

    Adamovich, B A / Gavrilov, B A / Grishaenkov, B G / Nefedov, Y G

    Acta astronautica

    2001  Volume 1, Issue 11-12, Page(s) 1331–1336

    Abstract: The purpose of the integrated physiologico-hygienic and biotechnological laboratory experiment was to evaluate the effect of life support subsytems placed inside a sealed cabin on the cabin environment and, consequently, on the human performance and ... ...

    Abstract The purpose of the integrated physiologico-hygienic and biotechnological laboratory experiment was to evaluate the effect of life support subsytems placed inside a sealed cabin on the cabin environment and, consequently, on the human performance and activity, and also to assess the operability of subsystems by the crewmen and disclose any resulting difficulties.
    MeSH term(s) Air Conditioning/methods ; Air Pollutants/analysis ; Air Pollution, Indoor ; Carbon Dioxide/analysis ; Ecological Systems, Closed ; Electrolysis/methods ; Environmental Microbiology ; Evaluation Studies as Topic ; Humans ; Life Support Systems/instrumentation ; Oxygen/analysis ; Space Flight/instrumentation ; Space Simulation ; Water/chemistry ; Weightlessness
    Chemical Substances Air Pollutants ; Water (059QF0KO0R) ; Carbon Dioxide (142M471B3J) ; Oxygen (S88TT14065)
    Language English
    Publishing date 2001-05-02
    Publishing country England
    Document type Journal Article
    ISSN 0094-5765
    ISSN 0094-5765
    DOI 10.1016/0094-5765(74)90079-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Detection of phosphorylated histone H2AX in differentiated cells after X-ray irradiation.

    Gavrilov, B A / Firsanov, D V / Vezhenkova, I V / Solov'eva, L V / Mikhailov, V M / Tomilin, N B

    Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections

    2007  Volume 414, Page(s) 239–241

    MeSH term(s) Animals ; Cell Differentiation/radiation effects ; Cell Nucleus/metabolism ; Heart/radiation effects ; Histones/metabolism ; Humans ; Kidney/cytology ; Kidney/metabolism ; Kidney/radiation effects ; Mice ; Myocardium/cytology ; Myocardium/metabolism ; Phosphorylation/radiation effects ; X-Rays
    Chemical Substances Histones ; gamma-H2AX protein, mouse
    Language English
    Publishing date 2007-07-13
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 204604-0
    ISSN 0012-4966
    ISSN 0012-4966
    DOI 10.1134/s0012496607030209
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 753: Show issues Location:
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  3. Article: Strukturnye preobrazovaniia interfaznykh IaOR v opukholevykh kletkakh rabdomiosarkomy PA-23, indutsirovannye okalaikovoĭ kislotoĭ.

    Proshin, S N / Kaminskaia, E V / Kuzovatov, S N / Vakhtin, Iu B / Gavrilov, B A / Kosiakova, G P / Iakovlev, A F

    Tsitologiia

    2001  Volume 43, Issue 8, Page(s) 738–741

    Abstract: It has been recently shown that okadaic acid (OA), an inhibitor of dephosphorilation, is capable of inducing changes in the nucleolar organizer regions (AgNORs) of some mammalian cells. Our work was focused on studying the structural changes in AgNORs of ...

    Title translation Structural changes of the nucleolar organizing regions in rhabdomyosarcoma RA-23 tumor cells induced by okadaic acid.
    Abstract It has been recently shown that okadaic acid (OA), an inhibitor of dephosphorilation, is capable of inducing changes in the nucleolar organizer regions (AgNORs) of some mammalian cells. Our work was focused on studying the structural changes in AgNORs of tumour cells of rat rhabdomyosarcoma RA-23 by their exposure to 100 nM OA. A standard silver staining procedure of interphase AgNORs in tumour cells was used. We measured no less than 100 tumour cells in each clone. In the examined tumour cell populations, the index of interphase AgNORs varied from 1.54 to 4.35. A clear structure and form of AgNORs was not observed in 30% okadaic acid-treated tumour cells, as opposed to 10% of the control ones. AgNORs in these cells looked like a mixture of thin threads encompassing some dark dots lying, mostly, separately. Additional procedures of tumour cell staining with Giemsa and fluorescent dye Hoechst 33,258, respectively, revealed that such structures were not chromosomes. Meanwhile, the frequency of cells at the stage of prophase exceeded 3%, as opposed to the control, where the frequency of cells at this stage was less than 0.5%. Thus, we can conclude that we have detected specific changes in AgNORs and chromatin structure of okadaic acid-treated tumour cells.
    MeSH term(s) Animals ; Azure Stains ; Bisbenzimidazole ; Enzyme Inhibitors/pharmacology ; Interphase ; Nucleolus Organizer Region/drug effects ; Nucleolus Organizer Region/ultrastructure ; Okadaic Acid/pharmacology ; Phosphorylation ; Rats ; Rhabdomyosarcoma/ultrastructure ; Tumor Cells, Cultured
    Chemical Substances Azure Stains ; Enzyme Inhibitors ; Okadaic Acid (1W21G5Q4N2) ; Bisbenzimidazole (LHQ7J5KV9B)
    Language Russian
    Publishing date 2001
    Publishing country Russia (Federation)
    Document type English Abstract ; Journal Article
    ZDB-ID 280565-0
    ISSN 0041-3771
    ISSN 0041-3771
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 1134: Show issues Location:
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