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  1. AU="Geßler, T"
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  1. Book ; Thesis: Aerosoltherapie der Pulmonalen Hypertonie

    Gessler, Tobias

    (Edition scientifique)

    2018  

    Author's details Tobias Gessler
    Series title Edition scientifique
    Keywords Aerosoltherapie ; Allergene ; Allergie ; Allergieimpfung ; Anwendung ; Asthma ; Atem ; Atemnot ; Cortison ; Ernährung ; Habilitation ; Hausstaub ; Heuschnupfen ; Hyposensibilisierung ; Immunität ; Impfung ; Inhalation ; Inhalator ; Luft ; Lunge ; Milben ; Nanopartikel ; Nitrite ; Polen ; Respirationstrakt ; Schwellung ; Therapie ; Tierallergie ; bronchial
    Subject code 610
    Language German ; English
    Size 224 Seiten, Illustrationen, Diagramme, 21 cm
    Edition 1. Auflage
    Publisher VVB Laufersweiler Verlag
    Publishing place Giessen
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Habilitationsschrift, Justus-Liebig-Universität Gießen, 2016
    Note Enthält Sonderabdrucke in englischer Sprache
    HBZ-ID HT020366924
    ISBN 978-3-8359-6449-5 ; 3-8359-6449-6
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2020 A 226 available for loan (reading room) Lesesaal EG

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  2. Book: Aerosoltherapie der Pulmonalen Hypertonie

    Gessler, Tobias

    (Edition Scientifique)

    2018  

    Abstract: Die Pulmonal Arterielle Hypertonie (PAH) ist eine seltene, aber schwerwiegende und lebensbedrohliche Erkrankung der distalen pulmonalen Arterien/Arteriolen, die durch einen Anstieg des Gefäßwiderstands und des Blutdrucks im Lungenkreislauf gekennzeichnet ...

    Series title Edition Scientifique
    Abstract Die Pulmonal Arterielle Hypertonie (PAH) ist eine seltene, aber schwerwiegende und lebensbedrohliche Erkrankung der distalen pulmonalen Arterien/Arteriolen, die durch einen Anstieg des Gefäßwiderstands und des Blutdrucks im Lungenkreislauf gekennzeichnet ist. Noch bis Ende des letzten Jahrhunderts waren bis auf das nebenwirkungsreiche intravenöse Prostazyklin keine spezifischen Medikamente verfügbar. Der pathophysiologische Hintergrund eines Ungleichgewichts zwischen Vasokonstriktion und Vas...
    Keywords Ernährung ; Nitrite ; Habilitation ; Hyposensibilisierung ; Allergene ; Nanopartikel ; Polen ; Cortison ; Allergie ; Hausstaub ; Impfung ; Tierallergie ; Allergieimpfung ; Respirationstrakt ; Lunge ; Luft ; Heuschnupfen ; Schwellung ; Therapie ; Immunität ; Aerosoltherapie ; Asthma ; Milben ; Atem ; Inhalator ; Atemnot ; bronchial ; Anwendung ; Inhalation
    Language German
    Size 232 p.
    Publisher VVB Laufersweiler Verlag
    Document type Book
    Note Hochschulschriften Medizin
    Format 146 x 210
    ISBN 9783835964495 ; 3835964496
    Database PDA

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  3. Book ; Thesis: Einfluss der Ventilation und Perfusion auf die pulmonale Stickstoffmonoxid-Bildung im Modell der isolierten Kaninchenlunge

    Gessler, Tobias

    2013  

    Author's details vorgelegt von Tobias Gessler
    Keywords Lungenkreislauf ; Stickstoffmonoxid ; Ventilation ; Perfusion ; Isoliert perfundiertes Organ ; Tiermodell
    Subject Perfusion ; Physiologische Beatmung ; Lungenventilation ; Lungenbelüftung ; Kleiner Kreislauf ; Pulmonalkreislauf
    Language German
    Size 111 S. : graph. Darst.
    Publisher VVB Laufersweiler Verlag
    Publishing place Gießen, Lahn
    Publishing country Germany
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Gießen, Univ., Diss., 2013
    HBZ-ID HT017631401
    ISBN 978-3-8359-6000-8 ; 3-8359-6000-8
    Database Catalogue ZB MED Medicine, Health

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    In stock of ZB MED Cologne/Königswinter

    Shelf markLoan statusLocation
    2013 A 831 available for loan (reading room) Lesesaal EG

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  4. Article ; Online: lloprost delivered via the BREELIB

    Gessler, Tobias

    Therapeutic advances in respiratory disease

    2019  Volume 13, Page(s) 1753466619835497

    Abstract: Inhaled iloprost is a well-established medication to treat pulmonary arterial hypertension (PAH), a serious and potentially fatal disease of the pulmonary resistance vessels. The therapeutic administration of iloprost requires six to nine inhalations per ...

    Abstract Inhaled iloprost is a well-established medication to treat pulmonary arterial hypertension (PAH), a serious and potentially fatal disease of the pulmonary resistance vessels. The therapeutic administration of iloprost requires six to nine inhalations per day, due to the short biological half-life of this prostacyclin analogue. The I-Neb
    MeSH term(s) Administration, Inhalation ; Drug Administration Schedule ; Half-Life ; Humans ; Hypertension, Pulmonary/drug therapy ; Hypertension, Pulmonary/physiopathology ; Iloprost/administration & dosage ; Iloprost/adverse effects ; Iloprost/pharmacokinetics ; Nebulizers and Vaporizers ; Time Factors ; Vascular Resistance ; Vasodilator Agents/administration & dosage ; Vasodilator Agents/adverse effects ; Vasodilator Agents/pharmacokinetics
    Chemical Substances Vasodilator Agents ; Iloprost (JED5K35YGL)
    Language English
    Publishing date 2019-02-28
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2476459-0
    ISSN 1753-4666 ; 1753-4658
    ISSN (online) 1753-4666
    ISSN 1753-4658
    DOI 10.1177/1753466619835497
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6753: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Inhalation of repurposed drugs to treat pulmonary hypertension.

    Gessler, Tobias

    Advanced drug delivery reviews

    2018  Volume 133, Page(s) 34–44

    Abstract: Pulmonary arterial hypertension (PAH) is a rare, but severe and life-threatening disease characterized by vasoconstriction and remodeling of the pulmonary arterioles, leading to progressive increase in pulmonary vascular resistance and ultimately to ... ...

    Abstract Pulmonary arterial hypertension (PAH) is a rare, but severe and life-threatening disease characterized by vasoconstriction and remodeling of the pulmonary arterioles, leading to progressive increase in pulmonary vascular resistance and ultimately to right-heart failure. In the last two decades, significant progress in treatment of PAH has been made, with currently 12 drugs approved for targeted therapy. Among these, the stable prostacyclin analogues iloprost and treprostinil have been repurposed for inhalation. The paper highlights the development of the two drugs emphasizing the rationale and advantages of the inhalative approach. Despite substantial advances in the specific, mainly vasodilatory PAH therapy, disease progression is mostly inevitable and mortality remains unacceptably high. Thus, introduction of new drugs targeting the cancer-like remodeling of the diseased pulmonary arteries is urgently needed. Inhalation offers pulmonary selectivity and will hopefully pioneer the repurposing of novel highly potent drugs for effective aerosol therapy of PAH.
    MeSH term(s) Administration, Inhalation ; Antihypertensive Agents/administration & dosage ; Antihypertensive Agents/therapeutic use ; Drug Repositioning ; Epoprostenol/administration & dosage ; Epoprostenol/analogs & derivatives ; Epoprostenol/therapeutic use ; Humans ; Hypertension, Pulmonary/drug therapy ; Iloprost/administration & dosage ; Iloprost/therapeutic use
    Chemical Substances Antihypertensive Agents ; Epoprostenol (DCR9Z582X0) ; Iloprost (JED5K35YGL) ; treprostinil (RUM6K67ESG)
    Language English
    Publishing date 2018-06-08
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 639113-8
    ISSN 1872-8294 ; 0169-409X
    ISSN (online) 1872-8294
    ISSN 0169-409X
    DOI 10.1016/j.addr.2018.06.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2241: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  6. Article ; Online: Inhalative Pharmakotherapie in der Zukunft--Nanocarrier für die pulmonale Applikation von Arzneistoffen.

    Gessler, T

    Pneumologie (Stuttgart, Germany)

    2009  Volume 63 Suppl 2, Page(s) S113–6

    Abstract: Nanotechnological approaches promise considerable potential for the treatment of pneumological diseases, especially asthma and COPD (Chronic Obstructive Pulmonary Disease). At present numerous nanotechnological approaches are under examination, which ... ...

    Title translation Inhalative pharmacotherapy in the future--nanocarriers for pulmonary drug delivery.
    Abstract Nanotechnological approaches promise considerable potential for the treatment of pneumological diseases, especially asthma and COPD (Chronic Obstructive Pulmonary Disease). At present numerous nanotechnological approaches are under examination, which allow a controlled release of encapsulated drugs or diagnostics. These include nanocarriers composed of polymers or anorganic materials, liposomes, micelles, quantum dots, dendrimeres, polymer conjugates and other systems. Polymeric nanocarriers give the opportunity to control the temporal as well as the spatial distribution of drugs within the lung. By varying the composition, structure and dimension nanoparticles could offer a controlled and prolonged duration of effect of the encapsulated drugs as well as a regional and cell-specific drug targeting within the lung.
    MeSH term(s) Administration, Inhalation ; Asthma/drug therapy ; Drug Carriers/administration & dosage ; Drug Carriers/chemistry ; Forecasting ; Humans ; Nanomedicine/trends ; Nanostructures/administration & dosage ; Nanostructures/chemistry ; Nanostructures/ultrastructure ; Pulmonary Disease, Chronic Obstructive/drug therapy
    Chemical Substances Drug Carriers
    Language German
    Publishing date 2009-12
    Publishing country Germany
    Document type English Abstract ; Journal Article ; Review
    ZDB-ID 607630-0
    ISSN 1438-8790 ; 0934-8387
    ISSN (online) 1438-8790
    ISSN 0934-8387
    DOI 10.1055/s-0029-1214768
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh II Zs.142: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 54: Show issues

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  7. Article ; Online: Conceptualizing, Measuring, and Mapping Contentiousness

    Gessler, Theresa / Hutter, Swen

    2021  

    Abstract: Portugal and Spain were among the countries hardest hit by the global financial crisis that led to the eurozone’s near collapse after the revelation of Greek public debt in late 2009. Both countries experienced a massive economic shock, as revealed by ... ...

    Abstract Portugal and Spain were among the countries hardest hit by the global financial crisis that led to the eurozone’s near collapse after the revelation of Greek public debt in late 2009. Both countries experienced a massive economic shock, as revealed by objective and subjective indicators (Chapter 3). Faced with a dire economic situation and increasing European pressure, the mainstream left in government – PS in Portugal and PSOE in Spain – announced severe austerity measures throughout 2009 and 2010 (Bremer and Vidal 2018). Consequently, the two countries saw union-organized protests against the measures early in the crisis (Accornero and Ramos Pinto 2015; Della Porta et al. 2017a; Kriesi et al. 2020; Portos 2019). Both countries experienced a turning point in 2011 when further noninstitutional actors entered the scene: Geração à Rasca [Screwed generation] in March 2011 in Portugal and 15M (named after the first large-scale protests on May 15, 2011) in Spain. According to some estimates, almost 5 percent of the Portuguese population took to the streets on March 12, 2011 (Carvalho 2018: 98). 15M and the battle cry of the central organizing network Democracia Real, Ya! [Real democracy now] led, after the first demonstration with about 20,000 participants on Puertas del Sol, to weeks of mass protests across the country.
    Keywords ddc:320
    Subject code 940
    Language English
    Publisher Cambridge: Cambridge University Press
    Publishing country de
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  8. Article ; Online: Social Media and Policy Responses to the COVID-19 Pandemic in Switzerland.

    Gilardi, Fabrizio / Gessler, Theresa / Kubli, Maël / Müller, Stefan

    Schweizerische Zeitschrift fur Politikwissenschaft = Revue suisse de science politique = Swiss political science review

    2021  Volume 27, Issue 2, Page(s) 243–256

    Abstract: We study the role of social media in debates regarding two policy responses to COVID-19 in Switzerland: face-mask rules and contact-tracing apps. We use a dictionary classifier to categorize 612'177 tweets by parties, politicians, and the public as well ... ...

    Abstract We study the role of social media in debates regarding two policy responses to COVID-19 in Switzerland: face-mask rules and contact-tracing apps. We use a dictionary classifier to categorize 612'177 tweets by parties, politicians, and the public as well as 441'458 articles published in 76 newspapers between February and August 2020. We distinguish between "problem" (COVID-19) and "solutions" (face masks and contact-tracing apps) and, using a vector autoregression approach, we analyze the relationship between their salience on social and traditional media, as well as among different groups on social media. We find that overall attention to COVID-19 was not driven by endogenous dynamics between the different actors. By contrast, the debate on face masks was led by the attentive public and by politicians, whereas parties and newspapers followed. The results illustrate how social media challenge the capacity of party and media elites to craft a consensus regarding the appropriateness of different measures as responses to a major crisis.
    Language English
    Publishing date 2021-05-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2085219-8
    ISSN 1662-6370 ; 1424-7755 ; 1420-3529
    ISSN (online) 1662-6370
    ISSN 1424-7755 ; 1420-3529
    DOI 10.1111/spsr.12458
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: No Country for Asylum Seekers? How Short-Term Exposure to Refugees Influences Attitudes and Voting Behavior in Hungary.

    Gessler, Theresa / Tóth, Gergő / Wachs, Johannes

    Political behavior

    2021  Volume 44, Issue 4, Page(s) 1813–1841

    Abstract: How does exposure to refugees influence political behavior? We present evidence from Hungary, a country with widespread anti-immigration attitudes, that short term exposure during the 2015 refugee crisis predicts anti-refugee voting and sentiment. We ... ...

    Abstract How does exposure to refugees influence political behavior? We present evidence from Hungary, a country with widespread anti-immigration attitudes, that short term exposure during the 2015 refugee crisis predicts anti-refugee voting and sentiment. We code exposure to refugees at the settlement level using reports from state media, an independent online news site, and an online social media aggregator. Settlements through which refugees traveled showed significantly higher anti-refugee voting in a national referendum in 2016. The effect decreases sharply with distance. Using a difference-in-differences model, we find that the far-right opposition gained, while the governing right-wing party lost votes in these settlements in subsequent parliamentary elections. This suggests incumbents are punished by voters skeptical of immigration regardless of their policy position. Survey data supports this finding of a competition among right-wing parties, as individuals in exposed settlements are more fearful of immigrants and support restrictive policies only if they identify as right-wing.
    Language English
    Publishing date 2021-02-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2018635-6
    ISSN 1573-6687 ; 0190-9320
    ISSN (online) 1573-6687
    ISSN 0190-9320
    DOI 10.1007/s11109-021-09682-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Book ; Online ; Thesis: Development of FPGA-based algorithms for the data acquisition of the Belle II pixel detector

    Geßler, Thomas

    2015  

    Title variant Entwicklung von FPGA-basierten Algorithmen für die Datenaufnahme des Belle II Pixeldetektors
    Author's details Thomas Geßler
    Language English
    Size Online-Ressource
    Publisher Universitätsbibliothek
    Publishing place Gießen
    Document type Book ; Online ; Thesis
    Thesis / German Habilitation thesis Gießen, Justus-Liebig-Universität, Diss., 2015
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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