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  1. Article ; Online: Isolated V-Shaped Sternal Cleft - A Rare Chest Wall Malformation.

    Gebremariam, Dawit Seyoum / Miruts, Asmamaw / Desta, Kibrom Gebreselassie

    Pediatric health, medicine and therapeutics

    2023  Volume 14, Page(s) 81–87

    Abstract: Sternal cleft is a rare chest wall anomaly resulting from a failure of the lateral mesodermal folds to migrate to the midline, causing a cleft in the early stage of embryological development. This can be a complete or partial defect. It can also occur as ...

    Abstract Sternal cleft is a rare chest wall anomaly resulting from a failure of the lateral mesodermal folds to migrate to the midline, causing a cleft in the early stage of embryological development. This can be a complete or partial defect. It can also occur as an isolated anomaly or in association with other syndromes. Fetal sonographic diagnosis of this defect is possible, but less practiced. After birth, this defect can be easily diagnosed clinically because of the presence of paradoxical chest wall movement. The flexibility of the thorax is maximal and compression of the underlying structures is minimal during the neonatal and early infancy period, and this period is the preferred time for surgical repair. We report a 39-day-old infant who presented with an isolated V-shaped inferior sternal cleft, its surgical primary closure, and postoperative course.
    Language English
    Publishing date 2023-03-04
    Publishing country New Zealand
    Document type Case Reports
    ZDB-ID 2616891-1
    ISSN 1179-9927 ; 1179-9927
    ISSN (online) 1179-9927
    ISSN 1179-9927
    DOI 10.2147/PHMT.S397462
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Neonatal Seizure Pattern, Outcome, and its Predictors Among Neonates Admitted to NICU of Ayder Comprehensive Specialized Hospital, Mekelle, Tigray, Ethiopia.

    Weldegerima, Kiros / Gebremariam, Dawit Seyoum / Haftu, Hansa / Berhe, Gebretsadik / Hadgu, Amanuel / Mohammedamin, Mohammed Mustefa

    International journal of general medicine

    2023  Volume 16, Page(s) 4343–4355

    Abstract: Background: Seizure is the most frequently observed symptom of neurological disorders and an important determinant of outcome during neonatal period. In clinical practice, it is prevalent and observed in neonates admitted to hospital in low-resources ... ...

    Abstract Background: Seizure is the most frequently observed symptom of neurological disorders and an important determinant of outcome during neonatal period. In clinical practice, it is prevalent and observed in neonates admitted to hospital in low-resources countries, but due to the paucity of studies in these regions, little is known about its pattern, clinical outcomes of hospitalization, and its predictors. Therefore, aims to evaluate seizure patterns, clinical outcomes, and its predictors among neonates admitted to the NICU of ACSH, Mekelle, and Tigray.
    Methods: A hospital-based cross-sectional study design was conducted among neonates with neonatal seizures admitted to NICU of Ayder Comprehensive Specialized Hospital. Data collection was done from record reviews. SPSS Version 25 was used. Descriptive statistics and bivariate logistic regressions where a p-value of <0.05 is considered statistically significant.
    Results: Out of 1622 NICU admissions, 155 (9.6%) were cases of neonatal seizure. The most frequently observed types of seizure in this study were subtle 70 (45.1%) and tonic 49 (31.6%) respectively. At the end of hospitalization 70.3% of neonates were discharged improved, 21.3% of neonates died and 8.4% of neonates had severe neurologic deficits. Poorly controlled seizures (AOR 4.8, 95% CI 2.6-9.2), prolonged duration of labor (AOR 4.3, 95% CI 2.2-8.8) and seizure onset <72 hours (AOR 3.7, 95% CI 1.6-8.5), respectively, were found to be independent predictors of poor neonatal outcome.
    Conclusion: Of all neonatal admissions, neonatal seizure was observed in close to 9.6%. The most frequently observed type of seizure was subtle. Of those admitted neonates, 30% had poor outcomes following the end of their hospitalization or when they leave against medical advice for lack of improvement). Poorly controlled seizures, prolonged duration of labor, and seizure onset <72 hours were independent predictors of poor neonatal outcomes.
    Language English
    Publishing date 2023-09-25
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2452220-X
    ISSN 1178-7074
    ISSN 1178-7074
    DOI 10.2147/IJGM.S414420
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Practice of Kangaroo Mother Care Among Low-Birth-Weight Infants Discharged from Health Facilities and Its Outcome in Mekelle City, Tigray, Northern Ethiopia.

    Gidey, Selamwit / Gebremariam, Dawit Seyoum / Hadush, Marta Yemane / Berhe, Amanuel / Abay, Tedros Hailu / Medhanyie, Araya Abrha / Beyene, Selemawit Asfaw / Abraha, Tadele Tesfean / Zelelow, Yibrah Berhe

    International journal of general medicine

    2023  Volume 16, Page(s) 757–768

    Abstract: Background: Kangaroo mother care is a proven intervention shown to be effective in reducing neonatal mortality among low-birth-weight infants. The paucity of evidence regarding the practice at home can be highlighted. This study aimed to assess the ... ...

    Abstract Background: Kangaroo mother care is a proven intervention shown to be effective in reducing neonatal mortality among low-birth-weight infants. The paucity of evidence regarding the practice at home can be highlighted. This study aimed to assess the practice and outcome of kangaroo mother care at home among mothers having low-birth-weight infants discharged from two hospitals in Mekelle, Tigray, Ethiopia.
    Methods: A prospective cohort study was conducted among 101 paired mothers and low-birth-weight neonates discharged from Ayder and Mekelle Hospitals. Non-probability purposive sampling was used to select 101 infants. Data were collected from patient charts in both hospitals using interviewer-administered structured questionnaire, anthropometric measurements and were then analyzed using SPSS version 20. Characteristics were analyzed using descriptive statistics. Bivariate analysis was used, and variables with p-value <0.25 were exported to multivariable logistic regression and statistical significance was set at a p-value <0.05.
    Results: Kangaroo mother care was continued at home in 99% of the infants. Three of the 101 infants died before the age of 4 months with a possible cause of death from respiratory failure. Exclusive breastfeeding was provided for 67% of the infants, and it was higher in infants who started kangaroo mother care within 24 hours of life (AOR 3.8, 95% CI 1.07-13.25). Malnutrition was higher in those with birth weight <1500 grams (AOR 7.3,95% CI 1.63-32.59); small for gestational age (AOR 4.8,95% CI 1.41-16.31) and those provided kangaroo mother care for <8 hours per day (AOR 4.5,95% CI 1.40-16.31).
    Conclusion: Early initiation and prolonged duration of kangaroo mother care were associated with increased exclusive breastfeeding practice and decreased incidence of malnutrition. Kangaroo mother care should be promoted at the community level.
    Language English
    Publishing date 2023-02-28
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2452220-X
    ISSN 1178-7074
    ISSN 1178-7074
    DOI 10.2147/IJGM.S396471
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Barriers and Enablers of KMC Implementation in Health Facility and Community of Tigray Region, Northern Ethiopia: Formative Research.

    Hadush, Marta Yemane / Gebremariam, Dawit Seyoum / Beyene, Selemawit Asfaw / Abay, Tedros Hailu / Berhe, Amanuel Hadgu / Zelelew, Yibrah Berhe / Asmelash, Tirhas / Ashebir, Fisseha / Amare, Samson Yohannes / Hadush, Znabu / Medhanyie, Araya Abrha

    Pediatric health, medicine and therapeutics

    2022  Volume 13, Page(s) 297–307

    Abstract: Background: Kangaroo mother care (KMC) is an evidence-based approach to reducing morbidity and mortality in low-birth-weight and preterm newborns. Barriers for KMC and its effective practice at a larger scale are highly affected by contextual factors. ... ...

    Abstract Background: Kangaroo mother care (KMC) is an evidence-based approach to reducing morbidity and mortality in low-birth-weight and preterm newborns. Barriers for KMC and its effective practice at a larger scale are highly affected by contextual factors. The purpose of this study is to explore barriers and enablers in the community and health facilities for implementation and continuation of KMC.
    Methods: This formative study employed a qualitative exploratory approach using focus group discussions and in-depth interviews in five zones of Tigray region, Northern Ethiopia. A total of 16 focus group discussions and 46 in-depth interviews were conducted with health workers and community members. The whole process of data collection took an iterative approach. An inductive thematic analysis was done by going through the transcribed data using ATLAS.ti software.
    Results: The current study found that problems of infrastructure and equipment for KMC practice, shortage of staff, and absence of trained health workers as the most frequently mentioned barriers by health workers. Low level of awareness, lack of support, mother being responsible for the rest of the family, holding babies in the front being traditionally unacceptable, and preference of incubators for better care of small babies were among the barriers identified in the community. Presence of community health workers and the positive attitude of the community towards them, as well as antenatal and postnatal care were among the favorable conditions for the implementation of KMC at health facilities and continuation of KMC at home.
    Conclusion: Empowering health workers through training to identify preterm and low-birth-weight babies, to do follow-ups after discharge, and creating awareness in the community to change the perception of kangaroo mother care are necessary.
    Language English
    Publishing date 2022-09-08
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2616891-1
    ISSN 1179-9927 ; 1179-9927
    ISSN (online) 1179-9927
    ISSN 1179-9927
    DOI 10.2147/PHMT.S369858
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Achieving high coverage of Kangaroo mother care practice is possible: Lessons from implementation research for accelerating scale-up in Tigray Region, Ethiopia.

    Beyene, Selemawit Asfaw / Hadush, Marta Yemane / Gebregizabher, Fisseha Ashebir / Gebremariam, Dawit Seyoum / Asmelash, Tirhas / Zelelow, Yibrah Berhe / Amare, Samson Yohannes / Abay, Tedros Hailu / Medhanyie, Araya Abrha

    Acta paediatrica (Oslo, Norway : 1992)

    2022  Volume 112 Suppl 473, Page(s) 77–85

    Abstract: Aim: To evaluate coverage of effective Kangaroo mother care (KMC) by developing a model that would result in high coverage (≥80%) of KMC for newborn weighing less than 2000 g at birth in Tigray region, Ethiopia.: Methods: The study used formative ... ...

    Abstract Aim: To evaluate coverage of effective Kangaroo mother care (KMC) by developing a model that would result in high coverage (≥80%) of KMC for newborn weighing less than 2000 g at birth in Tigray region, Ethiopia.
    Methods: The study used formative research and continuous programme learning in iterative cycles of model development and modification conducted in close collaboration with the Tigray Regional Health Bureau. Quantitative methods were used to evaluate the various models. All study facilities were enrolled simultaneously, and hospitals and health centres were considered to become KMC-providers.
    Results: The final scalable model implemented in two rural districts and one special urban zone of Tigray region attained the desired objective, with coverage of effective KMC of 82.3% at discharge.
    Conclusion: Achieving high coverage of KMC is possible through the design of context-specific implementation strategies. The key factors for success were the commitment and strong leadership from the regional health bureau, strong linkages within the health system and between different departments within health facilities, improved health worker knowledge, skills and attitudes, hospitals and health centres that supported KMC performance, and systematic generation and use of data for continuous quality improvement.
    MeSH term(s) Humans ; Infant, Newborn ; Child ; Infant, Low Birth Weight ; Kangaroo-Mother Care Method ; Ethiopia ; Hospitals ; Education, Continuing
    Language English
    Publishing date 2022-06-01
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 203487-6
    ISSN 1651-2227 ; 0365-1436 ; 0803-5253
    ISSN (online) 1651-2227
    ISSN 0365-1436 ; 0803-5253
    DOI 10.1111/apa.16374
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Scaling up Kangaroo Mother Care in Ethiopia and India: a multi-site implementation research study.

    Mony, Prem K / Tadele, Henok / Gobezayehu, Abebe Gebremariam / Chan, Grace J / Kumar, Aarti / Mazumder, Sarmila / Beyene, Selemawit Asfaw / Jayanna, Krishnamurthy / Kassa, Dejene Hailu / Mohammed, Hajira Amin / Estifanos, Abiy Seifu / Kumar, Pankaj / Jadaun, Arun Singh / Hailu Abay, Tedros / Washington, Maryann / W/Gebriel, Fitsum / Alamineh, Lamesgin / Fikre, Addisalem / Kumar, Alok /
    Trikha, Sonia / Ashebir Gebregizabher, Fisseha / Kar, Arin / Bilal, Selamawit Mengesha / Belew, Mulusew Lijalem / Debere, Mesfin Kote / Krishna, Raghav / Dalpath, Suresh Kumar / Amare, Samson Yohannes / Mohan, H L / Brune, Thomas / Sibley, Lynn M / Tariku, Abraham / Sahu, Arti / Kumar, Tarun / Hadush, Marta Yemane / Gowda, Prabhu Deva / Aziz, Khalid / Duguma, Dereje / Singh, Pramod Kumar / Darmstadt, Gary L / Agarwal, Ramesh / Gebremariam, Dawit Seyoum / Martines, Jose / Portela, Anayda / Jaiswal, Harsh Vardhan / Bahl, Rajiv / Rao Pn, Suman / Tadesse, Birkneh Tilahun / Cranmer, John N / Hailemariam, Damen / Kumar, Vishwajeet / Bhandari, Nita / Medhanyie, Araya Abrha

    BMJ global health

    2021  Volume 6, Issue 9

    Abstract: Objectives: Kangaroo Mother Care (KMC), prolonged skin-to-skin care of the low birth weight baby with the mother plus exclusive breastfeeding reduces neonatal mortality. Global KMC coverage is low. This study was conducted to develop and evaluate ... ...

    Abstract Objectives: Kangaroo Mother Care (KMC), prolonged skin-to-skin care of the low birth weight baby with the mother plus exclusive breastfeeding reduces neonatal mortality. Global KMC coverage is low. This study was conducted to develop and evaluate context-adapted implementation models to achieve improved coverage.
    Design: This study used mixed-methods applying implementation science to develop an adaptable strategy to improve implementation. Formative research informed the initial model which was refined in three iterative cycles. The models included three components: (1) maximising access to KMC-implementing facilities, (2) ensuring KMC initiation and maintenance in facilities and (3) supporting continuation at home postdischarge.
    Participants: 3804 infants of birth weight under 2000 g who survived the first 3 days, were available in the study area and whose mother resided in the study area.
    Main outcome measures: The primary outcomes were coverage of KMC during the 24 hours prior to discharge and at 7 days postdischarge.
    Results: Key barriers and solutions were identified for scaling up KMC. The resulting implementation model achieved high population-based coverage. KMC initiation reached 68%-86% of infants in Ethiopian sites and 87% in Indian sites. At discharge, KMC was provided to 68% of infants in Ethiopia and 55% in India. At 7 days postdischarge, KMC was provided to 53%-65% of infants in all sites, except Oromia (38%) and Karnataka (36%).
    Conclusions: This study shows how high coverage of KMC can be achieved using context-adapted models based on implementation science. They were supported by government leadership, health workers' conviction that KMC is the standard of care, women's and families' acceptance of KMC, and changes in infrastructure, policy, skills and practice.
    Trial registration numbers: ISRCTN12286667; CTRI/2017/07/008988; NCT03098069; NCT03419416; NCT03506698.
    MeSH term(s) Aftercare ; Ethiopia ; Female ; Humans ; India ; Infant, Newborn ; Kangaroo-Mother Care Method ; Patient Discharge
    Language English
    Publishing date 2021-08-09
    Publishing country England
    Document type Journal Article ; Observational Study ; Research Support, Non-U.S. Gov't
    ISSN 2059-7908
    ISSN 2059-7908
    DOI 10.1136/bmjgh-2021-005905
    Database MEDical Literature Analysis and Retrieval System OnLINE

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