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  1. Article ; Online: Personalization of Complementary Feeding in Children With Acute Food Protein-Induced Enterocolitis Syndrome.

    Miceli Sopo, Stefano / Mastellone, Francesco / Bersani, Giulia / Gelsomino, Mariannita

    The journal of allergy and clinical immunology. In practice

    2023  Volume 12, Issue 3, Page(s) 620–623

    Abstract: Food protein-induced enterocolitis syndrome (FPIES) is a food allergy that results in repetitive vomiting, lethargy, and pallor within 1 to 4 hours of food ingestion. One of the issues in its management is the introduction of new foods. Over the past 25 ... ...

    Abstract Food protein-induced enterocolitis syndrome (FPIES) is a food allergy that results in repetitive vomiting, lethargy, and pallor within 1 to 4 hours of food ingestion. One of the issues in its management is the introduction of new foods. Over the past 25 years, suggestions have been made mainly based on the likelihood that a given food family could induce an episode of acute FPIES. Thus, foods have been categorized into low, moderate, and high risk. The suggestion was always to postpone the introduction of moderate- or high-risk foods, leaving the decision whether to introduce them at home or in hospital to the doctor. These suggestions were designed for all children with acute FPIES, regardless of their geographical area. However, it is true that these suggestions are the result of expert opinion. In recent years, studies have been published that have shown that the risk category of foods varies according to geographical area and so does the prevalence of single FPIES versus multiple FPIES. For this reason, we believe that the introduction of new foods in the child with acute FPIES can and should be tailored according to the geographical area.
    MeSH term(s) Child ; Humans ; Infant ; Syndrome ; Food Hypersensitivity/epidemiology ; Food Hypersensitivity/therapy ; Vomiting ; Enterocolitis/epidemiology ; Enterocolitis/therapy ; Allergens ; Infant Nutritional Physiological Phenomena ; Dietary Proteins/adverse effects
    Chemical Substances Allergens ; Dietary Proteins
    Language English
    Publishing date 2023-09-29
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2843237-X
    ISSN 2213-2201 ; 2213-2198
    ISSN (online) 2213-2201
    ISSN 2213-2198
    DOI 10.1016/j.jaip.2023.09.022
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    Zs.A 7086: Show issues Location:
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  2. Article ; Online: Biopsy-sparing celiac disease diagnosis in children.

    Miceli Sopo, Stefano / Mastellone, Francesco / Bersani, Giulia / Di Noi, Silvia / Gelsomino, Mariannita

    Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver

    2023  Volume 55, Issue 8, Page(s) 1153–1155

    MeSH term(s) Humans ; Child ; Celiac Disease/diagnosis ; Biopsy ; Transglutaminases ; Autoantibodies
    Chemical Substances Transglutaminases (EC 2.3.2.13) ; Autoantibodies
    Language English
    Publishing date 2023-06-10
    Publishing country Netherlands
    Document type Letter ; Comment
    ZDB-ID 1459373-7
    ISSN 1878-3562 ; 1125-8055
    ISSN (online) 1878-3562
    ISSN 1125-8055
    DOI 10.1016/j.dld.2023.05.019
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    Zs.A 1134: Show issues Location:
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  3. Article ; Online: Non-allergic benign infantile proctocolitis: a neglected nosographic entity.

    Gelsomino, Mariannita / Sinatti, Dario / Miceli Sopo, Stefano

    BMJ case reports

    2021  Volume 14, Issue 10

    Abstract: The presence of rectal bleeding in the first months of life is very often diagnosed as food protein-induced allergic proctocolitis (FPIAP). The symptoms typically start in infancy, and most cases resolve by age 12 months. Infants with FPIAP usually ... ...

    Abstract The presence of rectal bleeding in the first months of life is very often diagnosed as food protein-induced allergic proctocolitis (FPIAP). The symptoms typically start in infancy, and most cases resolve by age 12 months. Infants with FPIAP usually present bloody stools mixed with mucus, with or without reduced stool consistency. Most affected infants are generally healthy-appearing. We used the story of an infant with rectal bleeding as a reminder that there is also the possibility of a form of benign non-allergic proctocolitis that is not usually included in the differential diagnosis. In the absence of warning signs and in case of infant well-being, it should be the first clinical entity to suspect. Therefore, we suggest we should wait at least 2 months before starting to eliminate cow milk or other foods from the diet.
    MeSH term(s) Allergens ; Animals ; Cattle ; Diet ; Female ; Food Hypersensitivity/complications ; Food Hypersensitivity/diagnosis ; Humans ; Infant ; Milk ; Milk Hypersensitivity/complications ; Milk Hypersensitivity/diagnosis ; Proctocolitis/diagnosis
    Chemical Substances Allergens
    Language English
    Publishing date 2021-10-19
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2021-244918
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: About the recommendation of the GINA strategy report on asthma step 1.

    Ferretti, Serena / Gelsomino, Mariannita / Miceli Sopo, Stefano

    The European respiratory journal

    2021  Volume 57, Issue 2

    MeSH term(s) Anti-Asthmatic Agents/therapeutic use ; Asthma/drug therapy ; Humans
    Chemical Substances Anti-Asthmatic Agents
    Language English
    Publishing date 2021-02-04
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 639359-7
    ISSN 1399-3003 ; 0903-1936
    ISSN (online) 1399-3003
    ISSN 0903-1936
    DOI 10.1183/13993003.03324-2020
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    Zs.A 2322: Show issues Location:
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    Zs.MO 292: Show issues

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  5. Article ; Online: Proposal of a Questionnaire for Acute Food Protein-induced Enterocolitis Syndrome Diagnosis.

    Sopo, Stefano Miceli / Mastellone, Francesco / Sinatti, Dario / Gelsomino, Mariannita

    Journal of pediatric gastroenterology and nutrition

    2022  Volume 74, Issue 6, Page(s) e160

    MeSH term(s) Dietary Proteins/adverse effects ; Enterocolitis/diagnosis ; Enterocolitis/etiology ; Food Hypersensitivity/complications ; Food Hypersensitivity/diagnosis ; Humans ; Infant ; Surveys and Questionnaires
    Chemical Substances Dietary Proteins
    Language English
    Publishing date 2022-02-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603201-1
    ISSN 1536-4801 ; 0277-2116
    ISSN (online) 1536-4801
    ISSN 0277-2116
    DOI 10.1097/MPG.0000000000003435
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    Zs.A 1728: Show issues Location:
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  6. Article ; Online: Reply to Barni et al.

    Miceli Sopo, Stefano / Sinatti, Dario / Gelsomino, Mariannita

    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

    2021  Volume 32, Issue 7, Page(s) 1590

    Language English
    Publishing date 2021-06-18
    Publishing country England
    Document type Letter
    ZDB-ID 1057059-7
    ISSN 1399-3038 ; 0905-6157 ; 0906-5784
    ISSN (online) 1399-3038
    ISSN 0905-6157 ; 0906-5784
    DOI 10.1111/pai.13566
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    Zs.A 3096: Show issues Location:
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  7. Article ; Online: Retrospective analysis of 222 oral food challenges with a single dose in acute food protein-induced enterocolitis syndrome.

    Miceli Sopo, Stefano / Sinatti, Dario / Gelsomino, Mariannita

    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology

    2021  Volume 32, Issue 5, Page(s) 1066–1072

    Abstract: Background: The method of performing oral food challenge (OFC) in acute food protein-induced enterocolitis syndrome (FPIES) has not been systematically studied. Therefore, there is a certain variability in the choice of the various centers.: Methods: ...

    Abstract Background: The method of performing oral food challenge (OFC) in acute food protein-induced enterocolitis syndrome (FPIES) has not been systematically studied. Therefore, there is a certain variability in the choice of the various centers.
    Methods: Since 2011, we have been performing OFC for acute FPIES with a single dose of culprit food, a full serving size for age. In case of atypical FPIES (skin prick test, SPT, positive), we applied this protocol only if the description of previous adverse reactions was compatible with that of a classic acute FPIES, if other IgE-mediated food allergies were absent, and if the mean diameter of the wheal evoked by the SPT with the challenged food was ≤5 mm. We have retrospectively analyzed 222 OFCs from 2011 to 2020. The grading of reactions was carried out according to the International Consensus Guidelines on FPIES of 2017.
    Results: Forty-eight of 222 OFC (21.6%) failed. The mild reactions were 22 of 48 (45.8%), the moderate ones 22 of 48 (45.8%), and the severe ones 4 of 48 (8.4%) failed OFCs. The tested food processing (in the case of cow milk and chicken egg) did affect neither probability nor severity of the reaction. Patients with positive SPT for the tested food presented four times more severe reactions (2 of 9 failed OFC, 22.2%) than patients with negative SPT (2 of 39 failed OFC, 5.1%) (P = .316).
    Conclusions: The administration of a single dose in a full serving size for age appears to be a sufficiently safe method for OFC for acute FPIES, with the benefit of saving time. In patients with positive SPT for the tested food, it may be prudent to start with a smaller dose carrying on, in the absence of adverse reactions, with the administration of the full dose after a 4-hour observation.
    MeSH term(s) Allergens ; Animals ; Cattle ; Dietary Proteins ; Enterocolitis/diagnosis ; Enterocolitis/etiology ; Female ; Food Hypersensitivity/diagnosis ; Humans ; Infant ; Retrospective Studies ; Skin Tests
    Chemical Substances Allergens ; Dietary Proteins
    Language English
    Publishing date 2021-03-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 1057059-7
    ISSN 1399-3038 ; 0905-6157 ; 0906-5784
    ISSN (online) 1399-3038
    ISSN 0905-6157 ; 0906-5784
    DOI 10.1111/pai.13489
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    Zs.A 3096: Show issues Location:
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  8. Article ; Online: Functional constipation related to cow's milk allergy in children: A management proposal.

    Gelsomino, Mariannita / Vescovo, Ester Del / Bersani, Giulia / Sopo, Stefano Miceli

    Allergologia et immunopathologia

    2021  Volume 49, Issue 3, Page(s) 17–20

    Abstract: Functional constipation (FC) is one of the most common disorders in childhood and has a negative impact on the quality of life of children. Scientific evidence regarding a causal relationship between FC and cow's milk allergy is controversial, as it is ... ...

    Abstract Functional constipation (FC) is one of the most common disorders in childhood and has a negative impact on the quality of life of children. Scientific evidence regarding a causal relationship between FC and cow's milk allergy is controversial, as it is also reported by the latest European Society for Paediatric Gastroenterology, Hepatology and Nutrition-North American Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN-NASPGHAN) recommendations. In the case of FC, routine allergometric tests are not recommended and the cows' milk-free diet is only proposed in the case of laxative-resistant constipation and only following the advice of an expert. Instead, after a careful review of the literature and in view of the many clinical cases encountered in our clinical practice, we believe that it is useful to propose cows' milk-free diet as first line for the treatment of FC at least in pre-school children and in children with a personal or family history of atopy or with a previous diagnosis of cow's milk protein allergy.
    MeSH term(s) Animals ; Child ; Child, Preschool ; Constipation/diet therapy ; Constipation/etiology ; Drug Resistance ; Female ; Guidelines as Topic ; Humans ; Laxatives/therapeutic use ; Male ; Milk/adverse effects ; Milk Hypersensitivity/complications ; Milk Proteins/administration & dosage ; Milk Proteins/adverse effects ; Quality of Life
    Chemical Substances Laxatives ; Milk Proteins
    Language English
    Publishing date 2021-05-01
    Publishing country Singapore
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 193144-1
    ISSN 1578-1267 ; 0301-0546
    ISSN (online) 1578-1267
    ISSN 0301-0546
    DOI 10.15586/aei.v49i3.72
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    Zs.A 1165: Show issues Location:
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  9. Article ; Online: Laparoscopic partial splenectomy using the harmonic scalpel for parenchymal transection: two case reports and review of the literature.

    Di Mauro, Davide / Fasano, Angelica / Gelsomino, Mariannita / Manzelli, Antonio

    Acta bio-medica : Atenei Parmensis

    2021  Volume 92, Issue S1, Page(s) e2021137

    Abstract: Laparoscopic splenectomy is nowadays widely performed for the treatment of benign and malignant diseases of the spleen. However, removing the spleen increases the risk of postoperative infections, therefore patients need long-life antibiotics. ... ...

    Abstract Laparoscopic splenectomy is nowadays widely performed for the treatment of benign and malignant diseases of the spleen. However, removing the spleen increases the risk of postoperative infections, therefore patients need long-life antibiotics. Advancement in surgical technique and instrumentation have led to the development of partial splenectomy, which is mainly indicated to treat localized lesions of the spleen. The main advantage is the preservation of the immune function, so that long-life prescription of antibiotics is no longer needed. The introduction of the laparoscopic approach to laparoscopic splenectomy seems to add further benefits, namely a faster recovery. We report two cases of benign splenic cysts, which were treated by laparoscopic partial splenectomy. Technical aspects on the parenchymal transection and data from the most recent literature are discussed as well.
    MeSH term(s) Humans ; Laparoscopy ; Splenectomy ; Splenic Diseases/surgery
    Language English
    Publishing date 2021-04-30
    Publishing country Italy
    Document type Case Reports ; Journal Article ; Review
    ZDB-ID 2114240-3
    ISSN 2531-6745 ; 0392-4203
    ISSN (online) 2531-6745
    ISSN 0392-4203
    DOI 10.23750/abm.v92iS1.10186
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    Zs.B 925: Show issues Location:
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  10. Article ; Online: Using the physical activity rating questionnaire improved the diagnostic accuracy of the asthma control test.

    Miceli Sopo, Stefano / Del Vescovo, Ester / Gelsomino, Mariannita / Greco, Giuseppe

    Acta paediatrica (Oslo, Norway : 1992)

    2021  Volume 111, Issue 1, Page(s) 165–166

    MeSH term(s) Asthma/diagnosis ; Exercise ; Exercise Test ; Humans ; Surveys and Questionnaires
    Language English
    Publishing date 2021-09-20
    Publishing country Norway
    Document type Journal Article
    ZDB-ID 203487-6
    ISSN 1651-2227 ; 0365-1436 ; 0803-5253
    ISSN (online) 1651-2227
    ISSN 0365-1436 ; 0803-5253
    DOI 10.1111/apa.16108
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