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Article: [Effects of bu yang huan wu decoction on astrocytes after cerebral ischemia and reperfusion].

Lai, Zhen / Wang, Sha-yan / Geng, Xiao-yin / Deng, Chang-qing / Zhang, Ruan-zhang

Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica

2002  Volume 27, Issue 10, Page(s) 763–765

Abstract: Objective: To study the effects of Bu Yang Huan Wu Decoction on astrocytes after cerebral ischemia and reperfusion.: Method: Cerebral ischemia model in gerbils was produced by ligating bilateral common carotid artery. The dynamic expressin of GFAP ... ...

Abstract Objective: To study the effects of Bu Yang Huan Wu Decoction on astrocytes after cerebral ischemia and reperfusion.
Method: Cerebral ischemia model in gerbils was produced by ligating bilateral common carotid artery. The dynamic expressin of GFAP were determined by immunochemistry after cerebyal ischemia for 15 min followed by reperfusion for 24 hours and 48 hours.
Result: GFAP positive reactions reached a peak after cerebral ischemia for 15 min followed by reperfusion for 24 hours. Bu Yang Huan Wu Decoction decreased the expression. GFAP positive reactions decreased after cerebral ischemia for 15 min followed by reperfusion for 48 hours, Bu Yang Huan Wu Decoction increased the expression.
Conclusion: The regulation of Bu Yang Huan Wu Decoction on astrocytes after cerebral ischemia and reperfusion may be related to repairing process after cerebral ischemia.
MeSH term(s) Animals ; Astrocytes/drug effects ; Brain Ischemia/complications ; Drugs, Chinese Herbal/isolation & purification ; Drugs, Chinese Herbal/pharmacology ; Female ; Glial Fibrillary Acidic Protein/metabolism ; Hippocampus/metabolism ; Male ; Plants, Medicinal/chemistry ; Reperfusion Injury/etiology ; Reperfusion Injury/metabolism ; Reperfusion Injury/pathology
Chemical Substances Drugs, Chinese Herbal ; Glial Fibrillary Acidic Protein ; buyang huanwu
Language Chinese
Publishing date 2002-10
Publishing country China
Document type English Abstract ; Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID 1004649-5
ISSN 1001-5302 ; 0254-0029
ISSN 1001-5302 ; 0254-0029
Shelf mark
Zs.A 3056: Show issues Location:
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