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  1. Article ; Online: Management of Posttraumatic Enophthalmos Including Complex Secondary Deficits.

    Gengler, Isabelle / Hsieh, Tsung-Yen

    Facial plastic surgery : FPS

    2022  Volume 38, Issue 4, Page(s) 364–374

    Abstract: Posttraumatic enophthalmos (PE) arises when the ocular globe is displaced posteriorly and inferiorly in the orbital cavity due to a mismatch in orbital volume and orbital content. This most commonly happens after orbital fractures. The resulting ... ...

    Abstract Posttraumatic enophthalmos (PE) arises when the ocular globe is displaced posteriorly and inferiorly in the orbital cavity due to a mismatch in orbital volume and orbital content. This most commonly happens after orbital fractures. The resulting disruptions to aesthetic form and ocular functions often necessitate surgical correction for reconstruction and restoration. The purpose of surgical management of PE is to reconstruct orbital shape and volume as well as to restore any herniated orbital content. This can be particularly challenging in cases involving large defects that require complex orbital reconstruction. Recent advancements in computer-aided surgery have introduced innovative and important tools to assist surgeons with these difficult cases. The ability to create customized, patient-specific implants can facilitate reconstruction involving complicated anatomy. Additionally, intraoperative imaging and intraoperative navigation can serve as useful guides for surgeons to more accurately place implants, especially in cases with limited visualization, in order to achieve optimal outcomes.
    MeSH term(s) Humans ; Enophthalmos/etiology ; Enophthalmos/surgery ; Reconstructive Surgical Procedures/methods ; Dental Implants ; Esthetics, Dental ; Orbital Fractures/complications ; Orbital Fractures/surgery ; Orbit/surgery
    Chemical Substances Dental Implants
    Language English
    Publishing date 2022-05-11
    Publishing country United States
    Document type Journal Article
    ZDB-ID 630090-x
    ISSN 1098-8793 ; 0736-6825
    ISSN (online) 1098-8793
    ISSN 0736-6825
    DOI 10.1055/a-1849-5491
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Management of Posttraumatic Enophthalmos Including Complex Secondary Deficits

    Gengler, Isabelle / Hsieh, Tsung-yen

    Facial Plastic Surgery

    (Functional Facial Plastic Surgery)

    2022  Volume 38, Issue 04, Page(s) 364–374

    Abstract: Posttraumatic enophthalmos (PE) arises when the ocular globe is displaced posteriorly and inferiorly in the orbital cavity due to a mismatch in orbital volume and orbital content. This most commonly happens after orbital fractures. The resulting ... ...

    Series title Functional Facial Plastic Surgery
    Abstract Posttraumatic enophthalmos (PE) arises when the ocular globe is displaced posteriorly and inferiorly in the orbital cavity due to a mismatch in orbital volume and orbital content. This most commonly happens after orbital fractures. The resulting disruptions to aesthetic form and ocular functions often necessitate surgical correction for reconstruction and restoration. The purpose of surgical management of PE is to reconstruct orbital shape and volume as well as to restore any herniated orbital content. This can be particularly challenging in cases involving large defects that require complex orbital reconstruction. Recent advancements in computer-aided surgery have introduced innovative and important tools to assist surgeons with these difficult cases. The ability to create customized, patient-specific implants can facilitate reconstruction involving complicated anatomy. Additionally, intraoperative imaging and intraoperative navigation can serve as useful guides for surgeons to more accurately place implants, especially in cases with limited visualization, in order to achieve optimal outcomes.
    Keywords enophthalmos ; computer-aided surgery ; intraoperative navigation ; intraoperative imaging ; orbital fractures
    Language English
    Publishing date 2022-05-11
    Publisher Thieme Medical Publishers, Inc.
    Publishing place Stuttgart ; New York
    Document type Article
    ZDB-ID 630090-x
    ISSN 1098-8793 ; 0736-6825
    ISSN (online) 1098-8793
    ISSN 0736-6825
    DOI 10.1055/a-1849-5491
    Database Thieme publisher's database

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  3. Article ; Online: Early-Stage Glottic Carcinoma in the United States: Demographics and Treatment Choice.

    Friedman, Aaron D / Gengler, Isabelle / Altaye, Mekibib / Tabangin, Meredith E

    The Laryngoscope

    2022  Volume 133, Issue 4, Page(s) 901–907

    Abstract: Objective: Limited investigation of factors potentially contributing to treatment choice in early-stage glottic carcinoma (EGC) has been performed with large-scale data. The National Cancer Database (NCDB) represents >72% of all new cancer cases in the ... ...

    Abstract Objective: Limited investigation of factors potentially contributing to treatment choice in early-stage glottic carcinoma (EGC) has been performed with large-scale data. The National Cancer Database (NCDB) represents >72% of all new cancer cases in the United States. We hypothesized that NCDB variables may lend insight into treatment decisions between surgery and radiation for EGC.
    Methods: The NCDB was queried for all cases of T
    Results: 34,991 EGC patients received treatment: 6,687 (19%) surgery; 20,289 (58%) RT; and 8,015 (23%) surgery and RT. OR for receiving RT (vs. surgery alone) were >2 for: more advanced T stage cancers (OR 2.5 [95%CI: 2.3, 2.7]), treatment at non-academic facilities (OR 2.8, [95%CI: 2.6, 3.0]), and shorter travel distances to treatment centers (OR 2.2, [95%CI: 2.0, 2.4]). Surgery was more likely with treatment in the western US, higher income, private insurance, living in a metropolitan (vs. non-metropolitan) area, female gender, older age, and low facility volume. Hispanic ethnicity, education level, and race were not associated with treatment type in the multivariable model.
    Conclusion: Most patients in the NCDB receive first-line treatment with radiation for EGC, and this decision is associated with various tumor, patient, and treatment facility characteristics.
    Level of evidence: 4 Laryngoscope, 133:901-907, 2023.
    MeSH term(s) Humans ; Female ; United States ; Laryngeal Neoplasms/epidemiology ; Laryngeal Neoplasms/therapy ; Laryngeal Neoplasms/pathology ; Combined Modality Therapy ; Demography ; Carcinoma
    Language English
    Publishing date 2022-07-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80180-x
    ISSN 1531-4995 ; 0023-852X
    ISSN (online) 1531-4995
    ISSN 0023-852X
    DOI 10.1002/lary.30305
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  4. Article ; Online: The Impact of the Post-Traumatic Facial Reconstruction on Postoperative Weight Loss.

    Gengler, Isabelle / Min, Susie / Jiang, Megan / Zhang, Grace / Altaye, Mekibib / Radulesco, Thomas / Lechien, Jerome R / Hsieh, Tsung-Yen

    Ear, nose, & throat journal

    2024  , Page(s) 1455613241241114

    Abstract: Objectives: ...

    Abstract Objectives:
    Language English
    Publishing date 2024-03-20
    Publishing country United States
    Document type Journal Article
    ZDB-ID 750153-5
    ISSN 1942-7522 ; 0145-5613
    ISSN (online) 1942-7522
    ISSN 0145-5613
    DOI 10.1177/01455613241241114
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  5. Article ; Online: Acute or persistent mechanisms of dysphonia in COVID-19 patients.

    Lechien, Jerome R / Maniaci, Antonino / Gengler, Isabelle M / Barillari, Maria Rosaria / Vaira, Luigi A / Mayo-Yanez, Miguel

    American journal of otolaryngology

    2024  Volume 45, Issue 3, Page(s) 104223

    MeSH term(s) Humans ; COVID-19/complications ; Dysphonia/etiology ; Acute Disease ; Male ; Female ; Middle Aged ; SARS-CoV-2
    Language English
    Publishing date 2024-01-16
    Publishing country United States
    Document type Journal Article ; Letter
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2024.104223
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  6. Article ; Online: Prevalence of chemosensitive disorders with Omicron infections and the possible impacts of vaccination.

    Vaira, Luigi Angelo / De Riu, Giacomo / Mayo-Yáñez, Miguel / Gengler, Isabelle M / Lechien, Jerome R

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2023  Volume 129, Page(s) 205–206

    MeSH term(s) Humans ; Prevalence ; COVID-19 ; SARS-CoV-2 ; Vaccination
    Language English
    Publishing date 2023-02-15
    Publishing country Canada
    Document type Letter ; Comment
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2023.02.007
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  7. Article ; Online: Dysphagia after supraglottic laryngeal cancer surgery.

    Lechien, Jerome R / Chiesa-Estomba, Carlos M / Maniaci, Antonino / Vaira, Luigi A / Gengler, Isabelle M

    American journal of otolaryngology

    2023  Volume 44, Issue 4, Page(s) 103925

    MeSH term(s) Humans ; Laryngeal Neoplasms/surgery ; Laryngeal Neoplasms/pathology ; Deglutition Disorders/diagnosis ; Deglutition Disorders/etiology ; Deglutition Disorders/surgery ; Squamous Cell Carcinoma of Head and Neck/surgery ; Carcinoma, Squamous Cell/surgery ; Carcinoma, Squamous Cell/pathology ; Head and Neck Neoplasms/surgery ; Laryngectomy/adverse effects ; Retrospective Studies ; Neoplasm Staging
    Language English
    Publishing date 2023-05-05
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2023.103925
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  8. Article ; Online: Asthma, chronic rhinosinusitis and laryngopharyngeal reflux.

    Lechien, Jerome R / Maniaci, Antonino / Gengler, Isabelle M / Mayo-Yanez, Miguel / Vaira, Luigi A

    American journal of otolaryngology

    2023  Volume 44, Issue 5, Page(s) 103953

    MeSH term(s) Humans ; Laryngopharyngeal Reflux/complications ; Laryngopharyngeal Reflux/diagnosis ; Sinusitis/complications ; Sinusitis/diagnosis ; Sinusitis/therapy ; Chronic Disease ; Asthma/complications ; Asthma/diagnosis
    Language English
    Publishing date 2023-06-09
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2023.103953
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  9. Article ; Online: Laryngopharyngeal reflux in otitis media with effusion.

    Lechien, Jerome R / Maniaci, Antonino / Gengler, Isabelle M / Al Barajraji, Mejdeddine / Mayo-Yanez, Miguel

    American journal of otolaryngology

    2023  Volume 45, Issue 2, Page(s) 104152

    MeSH term(s) Humans ; Laryngopharyngeal Reflux/complications ; Laryngopharyngeal Reflux/diagnosis ; Otitis Media with Effusion/diagnosis ; Otitis Media with Effusion/etiology ; Otitis Media
    Language English
    Publishing date 2023-12-12
    Publishing country United States
    Document type Letter
    ZDB-ID 604541-8
    ISSN 1532-818X ; 0196-0709
    ISSN (online) 1532-818X
    ISSN 0196-0709
    DOI 10.1016/j.amjoto.2023.104152
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  10. Article ; Online: Olfactory Dysfunction: A Highly Prevalent Symptom of COVID-19 With Public Health Significance.

    Sedaghat, Ahmad R / Gengler, Isabelle / Speth, Marlene M

    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery

    2020  Volume 163, Issue 1, Page(s) 12–15

    Abstract: Objective: Coronavirus disease 2019 (COVID-19) is a global pandemic affecting millions of individuals, killing hundreds of thousands. Although typically described with characteristic symptoms of fever, cough, and shortness of breath, greater ... ...

    Abstract Objective: Coronavirus disease 2019 (COVID-19) is a global pandemic affecting millions of individuals, killing hundreds of thousands. Although typically described with characteristic symptoms of fever, cough, and shortness of breath, greater understanding of COVID-19 has revealed myriad clinical manifestations. Olfactory dysfunction (OD)-hyposmia and anosmia-has recently been recognized as an important symptom of COVID-19 and increasingly gained traction as a public health tool for identifying COVID-19 patients, in particular otherwise asymptomatic carriers who, unawares, may be major drivers of disease spread. The objective of this study is to review the scientific evidence about anosmia in COVID-19.
    Data sources: PubMed, Google Scholar, and Web of Science.
    Review methods: Comprehensive literature search of primary studies pertinent to the objectives of this review using the chosen data sources.
    Conclusions: Current evidence shows that OD is highly prevalent in COVID-19, with up to 80% of patients reporting subjective OD and objective olfactory testing potentially showing even higher prevalence. OD is frequently accompanied by taste dysfunction. Up to 25% of COVID-19 patients may experience sudden-onset OD as the first symptom. A large proportion of COVID-19 OD cases may resolve over the period of a few weeks.
    Implications for practice: Sudden anosmia should be considered a symptom of COVID-19. Assessing for sudden-onset anosmia may increase sensitivity of COVID-19 screening strategies, in particular for identifying patients at the earliest stages of disease. Since many cases of OD due to COVID-19 may resolve in the short term, conservative management, including observation, is reasonable, while advanced imaging is unnecessary.
    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Global Health ; Humans ; Olfaction Disorders/epidemiology ; Olfaction Disorders/etiology ; Olfaction Disorders/physiopathology ; Pandemics ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; Prevalence ; Public Health ; SARS-CoV-2 ; Smell
    Keywords covid19
    Language English
    Publishing date 2020-05-05
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 392085-9
    ISSN 1097-6817 ; 0161-6439 ; 0194-5998
    ISSN (online) 1097-6817
    ISSN 0161-6439 ; 0194-5998
    DOI 10.1177/0194599820926464
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