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  1. AU="Geno, Connie S"
  2. AU=Hussein Ahmed A.
  3. AU="Ringsten, Martin"

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  1. Article ; Online: In Regard to Soyfer et al.

    Ebner, Daniel K / Geno, Connie S / Ma, Daniel J

    International journal of radiation oncology, biology, physics

    2022  Volume 112, Issue 3, Page(s) 834–835

    Language English
    Publishing date 2022-01-31
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 197614-x
    ISSN 1879-355X ; 0360-3016
    ISSN (online) 1879-355X
    ISSN 0360-3016
    DOI 10.1016/j.ijrobp.2021.11.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1218: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Proton versus photon craniospinal irradiation for adult medulloblastoma: A dosimetric, toxicity, and exploratory cost analysis.

    Breen, William G / Geno, Connie S / Waddle, Mark R / Qian, Jing / Harmsen, William S / Burns, Terry C / Sener, Ugur T / Ruff, Michael W / Neth, Bryan J / Uhm, Joon H / Routman, David M / Yan, Elizabeth / Kruse, Jon J / Laack, Nadia N / Brown, Paul D / Mahajan, Anita

    Neuro-oncology advances

    2024  Volume 6, Issue 1, Page(s) vdae034

    Abstract: Background: This study aimed to determine whether proton craniospinal irradiation (CSI) decreased the dose to normal tissue and resulted in less toxicity than photon CSI for adult patients.: Methods: This single-institution retrospective analyzed ... ...

    Abstract Background: This study aimed to determine whether proton craniospinal irradiation (CSI) decreased the dose to normal tissue and resulted in less toxicity than photon CSI for adult patients.
    Methods: This single-institution retrospective analyzed differences in radiation doses, acute toxicity, and cost between proton and CSI for adult medulloblastoma patients.
    Results: Of 39 total patients, 20 were treated with photon CSI prior to 2015, and 19 were treated with proton CSI thereafter. Median age was 28 years (range 18-66). The molecular subtype was most commonly sonic hedgehog (68%). Patients most commonly received 36 Gy CSI in 20 fractions with a boost to 54-55.8 Gy (92%). Proton CSI delivered significantly lower mean doses to cochleae, lacrimal glands, lens, parotid glands, pharyngeal constrictors, esophagus, lungs, liver, and skin (all
    Conclusions: This study demonstrates dosimetric improvements with proton CSI, potentially leading to decreased acute toxicity including dysphagia and weight loss during treatment.
    Language English
    Publishing date 2024-03-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 3009682-0
    ISSN 2632-2498 ; 2632-2498
    ISSN (online) 2632-2498
    ISSN 2632-2498
    DOI 10.1093/noajnl/vdae034
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Does the dural resection bed need to be irradiated? Patterns of recurrence and implications for postoperative radiotherapy for temporal lobe gliomas.

    Teyateeti, Achiraya / Geno, Connie S / Stafford, Scott S / Mahajan, Anita / Yan, Elizabeth S / Merrell, Kenneth W / Laack, Nadia N / Parney, Ian F / Brown, Paul D / Jethwa, Krishan R

    Neuro-oncology practice

    2020  Volume 8, Issue 2, Page(s) 190–198

    Abstract: Background: Patterns of recurrence and survival with different surgical and radiotherapy (RT) techniques were evaluated to guide RT target volumes for patients with temporal lobe glioma.: Methods and materials: This retrospective cohort study ... ...

    Abstract Background: Patterns of recurrence and survival with different surgical and radiotherapy (RT) techniques were evaluated to guide RT target volumes for patients with temporal lobe glioma.
    Methods and materials: This retrospective cohort study included patients with World Health Organization grades II to IV temporal lobe glioma treated with either partial (PTL) or complete temporal lobectomy (CTL) followed by RT covering both the parenchymal and dural resection bed (whole-cavity radiotherapy [WCRT]) or the parenchymal resection bed only (partial-cavity radiotherapy [PCRT]). Patterns of recurrence, progression-free survival (PFS) and overall survival (OS) were evaluated.
    Results: Fifty-one patients were included and 84.3% of patients had high-grade glioma (HGG). CTL and PTL were performed for 11 (21.6%) and 40 (78.4%) patients, respectively. Median RT dose was 60 Gy (range, 40-76 Gy). There were 82.4% and 17.6% of patients who received WCRT and PCRT, respectively. Median follow-up time was 18.4 months (range, 4-161 months). Forty-six patients (90.2%) experienced disease recurrence, most commonly at the parenchymal resection bed (76.5%). No patients experienced an isolated dural recurrence. The median PFS and OS for the PCRT and WCRT cohorts were 8.6 vs 10.8 months (
    Conclusion: We identified no isolated dural recurrence and similar PFS and OS regardless of postoperative RT volume, whereas PCRT was associated with dose reduction to critical structures. Omission of dural RT may be considered a reasonable alternative approach. Further validation with larger comparative studies is warranted.
    Language English
    Publishing date 2020-11-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 2768945-1
    ISSN 2054-2585 ; 2054-2577
    ISSN (online) 2054-2585
    ISSN 2054-2577
    DOI 10.1093/nop/npaa073
    Database MEDical Literature Analysis and Retrieval System OnLINE

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