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  1. AU="Geoffroy, Pierre A"
  2. AU="Chapuis, J"
  3. AU="Berta, László"
  4. AU="Barzilay, Regina"
  5. AU="Schmidt, Michael Rahbek"
  6. AU=Tack J
  7. AU="Oh, Hye Min"
  8. AU=Gaffen Sarah L AU=Gaffen Sarah L
  9. AU="Schmitt, Christine"
  10. AU="McKay, Jackie"
  11. AU="Bellissimo, Catherine A"
  12. AU="Desai, Urja"
  13. AU="Chini, Maria Giovanna"
  14. AU="Xiao, Difei"
  15. AU="Ryan, Chris"
  16. AU="Omar Bazighifan"
  17. AU="Corominas Galbany, Jordi"
  18. AU=Fox Norma E
  19. AU="Hamilton, Shelia M"
  20. AU="Nichols, J Wylie"
  21. AU="Pesce R."
  22. AU="Gambitta, P"
  23. AU="Imran, Aqeel"
  24. AU="Sharma, Yashoda"
  25. AU="Kosai, Jordyn"
  26. AU="Aroca Ferri, María"
  27. AU="Laba, Stephanie"
  28. AU="Kim, Ye-Sel"

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  1. Artikel ; Online: Dark skies before the storm: The Chronos syndrome.

    Geoffroy, Pierre A

    Bipolar disorders

    2023  Band 25, Heft 7, Seite(n) 608–609

    Mesh-Begriff(e) Humans ; Bipolar Disorder
    Sprache Englisch
    Erscheinungsdatum 2023-09-25
    Erscheinungsland Denmark
    Dokumenttyp Journal Article
    ZDB-ID 1472242-2
    ISSN 1399-5618 ; 1398-5647
    ISSN (online) 1399-5618
    ISSN 1398-5647
    DOI 10.1111/bdi.13380
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Insomnie et troubles psychiatriques.

    Maruani, Julia / Geoffroy, Pierre A

    La Revue du praticien

    2024  Band 74, Heft 3, Seite(n) 285–290

    Abstract: INSOMNIA AND PSYCHIATRIC DISORDERS. Insomnia is frequent in psychiatric disorders. In particular, insomnia can be a risk factor, as well as a comorbid condition, or a symptom and an early sign of psychiatric disorders. Insomnia may emerge during any ... ...

    Titelübersetzung Insomnia and psychiatric disorders.
    Abstract INSOMNIA AND PSYCHIATRIC DISORDERS. Insomnia is frequent in psychiatric disorders. In particular, insomnia can be a risk factor, as well as a comorbid condition, or a symptom and an early sign of psychiatric disorders. Insomnia may emerge during any stage of illness. It includes prodromal, first episode, acute, recurrence, and even remission stages, thereby being associated with a worse course of illness. Insomnia increased symptom severity, relapses or recurrences, and increased suicidal risk. Thus, insomnia is an important modifiable risk factor to prevent psychiatric disorders and/or achieve and maintain remission. Thereby insomnia evaluation and management should be a priority in psychiatric cares. Indeed, it has been demonstrated that targeting insomnia can not only improve insomnia itself but also have a positive impact on the trajectory of psychiatric disorders.
    Mesh-Begriff(e) Humans ; Sleep Initiation and Maintenance Disorders/diagnosis ; Sleep Initiation and Maintenance Disorders/epidemiology ; Sleep Initiation and Maintenance Disorders/therapy ; Mental Disorders/complications ; Mental Disorders/diagnosis ; Mental Disorders/epidemiology ; Psychotherapy ; Risk Factors
    Sprache Französisch
    Erscheinungsdatum 2024-03-29
    Erscheinungsland France
    Dokumenttyp English Abstract ; Journal Article
    ZDB-ID 205365-2
    ISSN 2101-017X ; 0035-2640
    ISSN (online) 2101-017X
    ISSN 0035-2640
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  3. Artikel ; Online: Eco-anxiety: Towards a medical model and the new framework of ecolalgia.

    Christodoulou, Nausicaa / Laaidi, Karine / Geoffroy, Pierre A

    Bipolar disorders

    2024  

    Abstract: Introduction: In the context of global warming, new terms emerged in the global media and in the psychology field to embody the negative feelings which come along with climate change such as 'eco-anxiety' or 'solastalgia'. The pathological character of ... ...

    Abstract Introduction: In the context of global warming, new terms emerged in the global media and in the psychology field to embody the negative feelings which come along with climate change such as 'eco-anxiety' or 'solastalgia'. The pathological character of these emotions is denied although medical opinion is often required for helping people to handle them. Also, no proper medical framework in the field exists to study and care for these patients.
    Methods: In this narrative review, we aim to (1) analyse the concept of eco-anxiety by focusing on its history and developed concepts, (2) summarize the different scales built to assess eco-anxiety and (3) propose a new medical framework.
    Results: We came out with a framework based on the transformation of a physiological adaptative behaviour the 'eco-distress'. It is composed of three dimensions: eco-anger, eco-grief and eco-worry, it is not debilitating in daily life and promotes coping strategies such as management of negative emotions and pro-environmental behaviours (PEB). It can transform itself into a pathological state, the 'ecolalgia', composed of two core dimensions: eco-anxiety and eco-depression, leading to functional impairment and decrease in PEB. If ecolalgia maintains over 15 days, we propose to consider it as a full psychiatric disorder needing medical advice.
    Conclusion: This new framework enables a novel approach that is necessary for the improved management of mental health issues related to climate change.
    Sprache Englisch
    Erscheinungsdatum 2024-05-13
    Erscheinungsland Denmark
    Dokumenttyp Journal Article ; Review
    ZDB-ID 1472242-2
    ISSN 1399-5618 ; 1398-5647
    ISSN (online) 1399-5618
    ISSN 1398-5647
    DOI 10.1111/bdi.13446
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  4. Artikel: Multi-Level Processes and Retina-Brain Pathways of Photic Regulation of Mood.

    Maruani, Julia / Geoffroy, Pierre A

    Journal of clinical medicine

    2022  Band 11, Heft 2

    Abstract: Light exerts powerful biological effects on mood regulation. Whereas the source of photic information affecting mood is well established at least via intrinsically photosensitive retinal ganglion cells (ipRGCs) secreting the melanopsin photopigment, the ... ...

    Abstract Light exerts powerful biological effects on mood regulation. Whereas the source of photic information affecting mood is well established at least via intrinsically photosensitive retinal ganglion cells (ipRGCs) secreting the melanopsin photopigment, the precise circuits that mediate the impact of light on depressive behaviors are not well understood. This review proposes two distinct retina-brain pathways of light effects on mood: (i) a suprachiasmatic nucleus (SCN)-dependent pathway with light effect on mood via the synchronization of biological rhythms, and (ii) a SCN-independent pathway with light effects on mood through modulation of the homeostatic process of sleep, alertness and emotion regulation: (1) light directly inhibits brain areas promoting sleep such as the ventrolateral preoptic nucleus (VLPO), and activates numerous brain areas involved in alertness such as, monoaminergic areas, thalamic regions and hypothalamic regions including orexin areas; (2) moreover, light seems to modulate mood through orexin-, serotonin- and dopamine-dependent pathways; (3) in addition, light activates brain emotional processing areas including the amygdala, the nucleus accumbens, the perihabenular nucleus, the left hippocampus and pathways such as the retina-ventral lateral geniculate nucleus and intergeniculate leaflet-lateral habenula pathway. This work synthetizes new insights into the neural basis required for light influence mood.
    Sprache Englisch
    Erscheinungsdatum 2022-01-16
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm11020448
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel: Sleep Immune Cross Talk and Insomnia.

    Akkaoui, Marine Ambar / Palagini, Laura / Geoffroy, Pierre A

    Advances in experimental medicine and biology

    2023  Band 1411, Seite(n) 263–273

    Abstract: Sleep and immunity have bidirectional relationships. In this chapter, we review the links between sleep and immunity, focusing on immune changes occurring in the insomnia disorder. During physiological sleep, there is a decrease of pro-inflammatory ... ...

    Abstract Sleep and immunity have bidirectional relationships. In this chapter, we review the links between sleep and immunity, focusing on immune changes occurring in the insomnia disorder. During physiological sleep, there is a decrease of pro-inflammatory cytokines (IL-1, IL-6 and TNF-α) and a decrease of anti-inflammatory cytokines (IL-4, IL-10). Examinations of ratios of pro-inflammatory and anti-inflammatory cytokines allow to identify rather a pro-inflammatory activity at the beginning of the night and confirm then anti-inflammatory during the second part of the night. Immune cells, as NK-cells, decrease in the blood, due to their migration to secondary lymphoid organs, but their activity increases. Inversely, a short sleep duration appears associated with increased inflammatory processes and increased risk of infection.Only few studies have investigated changes in immunity in patients with insomnia disorder. These studies suggest that insomnia disorder is related to deregulation of the immune system, with an increase in the level of pro-inflammatory cytokines and change in rate of secretion and a decrease in the level of lymphocyte. Insomnia treatments, particularly cognitive behavioral therapy (CBT-I), seems to have a restorative effect not only on sleep, but also on the associated inflammation. Melatonin also seems to reduce inflammation in patients suffering from insomnia disorder.More studies are necessary to better understand the pathophysiology of changes in immune system in patients suffering from insomnia disorders and their clinical implications.
    Mesh-Begriff(e) Humans ; Sleep Initiation and Maintenance Disorders/therapy ; Sleep/physiology ; Cytokines ; Cognitive Behavioral Therapy ; Inflammation
    Chemische Substanzen Cytokines
    Sprache Englisch
    Erscheinungsdatum 2023-03-22
    Erscheinungsland United States
    Dokumenttyp Review ; Journal Article
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-981-19-7376-5_12
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel ; Online: Clock Genes and Light Signaling Alterations in Bipolar Disorder: When the Biological Clock Is Off.

    Geoffroy, Pierre A

    Biological psychiatry

    2018  Band 84, Heft 11, Seite(n) 775–777

    Mesh-Begriff(e) ARNTL Transcription Factors ; Biological Clocks ; Bipolar Disorder ; CLOCK Proteins ; Humans ; Neuronal Plasticity
    Chemische Substanzen ARNTL Transcription Factors ; CLOCK Proteins (EC 2.3.1.48)
    Sprache Englisch
    Erscheinungsdatum 2018-11-09
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't ; Comment
    ZDB-ID 209434-4
    ISSN 1873-2402 ; 0006-3223
    ISSN (online) 1873-2402
    ISSN 0006-3223
    DOI 10.1016/j.biopsych.2018.09.006
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  7. Artikel: Redefining the relationship in digital care: A qualitative study of the Digital Therapeutic Alliance.

    Stern, Emilie / Breton, Zélia / Alexaline, Maïa / Geoffroy, Pierre A / Bungener, Catherine

    L'Encephale

    2024  

    Abstract: Digital therapeutic programs are emerging almost daily, offering the potential to reduce healthcare access inequalities by providing more flexible and accessible care options. However, as with traditional healthcare, the issue of patient engagement is ... ...

    Abstract Digital therapeutic programs are emerging almost daily, offering the potential to reduce healthcare access inequalities by providing more flexible and accessible care options. However, as with traditional healthcare, the issue of patient engagement is fundamental, and the latest research have reported that fewer than 30% of users complete these programs in their entirety. Hence, many authors emphasize the importance of studying the role of therapeutic alliances specifically adapted to digital care. The therapeutic alliance encompasses the collaborative aspects of the relationship between the therapist and the patient. In this context there is a need to reconceptualize the alliance within the context of digital healthcare as it can enhance engagement, adherence, and the effectiveness of such treatments. The objective of this qualitative study was to identify the components of the digital therapeutic alliance. A thematic analysis has identified three major themes that appear to constitute the digital therapeutic alliance among 44 users of an online program: trust in the program, perception of interactions, and feeling of consideration. These results prompted a discussion of the challenges of digital healthcare, including the terminology to use. The term "digital therapeutic adherence" is proposed, thereby opening up a field for research and clarification of this important concept distinct from traditional alliance.
    Sprache Englisch
    Erscheinungsdatum 2024-05-08
    Erscheinungsland France
    Dokumenttyp Journal Article
    ZDB-ID 214431-1
    ISSN 0013-7006
    ISSN 0013-7006
    DOI 10.1016/j.encep.2024.02.011
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Cognitive-behavioral therapies in the management of adolescents with cannabis use disorder (CUD): A systematic review.

    Mauries, Sibylle / Dufayet, Geoffrey / Lengereau, Ariane / Lejoyeux, Michel / Geoffroy, Pierre A / Dupong, Irène

    Drug and alcohol dependence

    2024  Band 260, Seite(n) 111321

    Abstract: Introduction: Cannabis currently stands as the most prevalent illicit substance used by adolescents in France. Its use is associated with an elevated risk of developing psychiatric disorder, affecting neuro-cognitive development, or leading to psycho- ... ...

    Abstract Introduction: Cannabis currently stands as the most prevalent illicit substance used by adolescents in France. Its use is associated with an elevated risk of developing psychiatric disorder, affecting neuro-cognitive development, or leading to psycho-social challenges in the long run. Cognitive-behavioral therapies (CBT) have emerged as a preferred approach for treating cannabis use disorders (CUD) in adults.
    Methods: This review is grounded in a systematic search of the PubMed scientific database for randomized controlled trials focusing on CBT treatment for adolescents (12-18 years old) with CUD.
    Results: Nine studies met the inclusion criteria. Currently, several variants of CBT-based treatments are available for adolescents, differing in duration based on the intended objectives (ranging from 3 to 24 weeks). These CBT therapies are often complemented by motivational interviewing or family therapy. Only two studies draw comparisons between CBT and alternative therapeutic approaches.
    Discussion: The current scientific literature in this field is limited, and the study designs display heterogeneity. However, abbreviated treatment courses appear to have value, especially within the adolescent population. These courses offer treatment advantages and may enhance treatment adherence among these young patients, who may face challenges in maintaining consistent follow-up. Additionally, involving parents in psychotherapeutic care seems to have a positive impact.
    Conclusion: CBT in adolescents with CUD appears to be a promising approach to assist with maintaining abstinence and managing emotions. However, given the diverse study designs found in the literature, conducting research with standardized treatments on larger patient cohorts would be valuable.
    Sprache Englisch
    Erscheinungsdatum 2024-05-04
    Erscheinungsland Ireland
    Dokumenttyp Journal Article ; Review
    ZDB-ID 519918-9
    ISSN 1879-0046 ; 0376-8716
    ISSN (online) 1879-0046
    ISSN 0376-8716
    DOI 10.1016/j.drugalcdep.2024.111321
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  9. Artikel ; Online: Dual Orexin Receptor Antagonists and Suicide Risk: Findings From the WHO Spontaneous Reporting Database.

    Salvo, Francesco / Micoulaud-Franchi, Jean-Arthur / Palagini, Laura / Geoffroy, Pierre A

    The Journal of clinical psychiatry

    2023  Band 84, Heft 6

    Mesh-Begriff(e) Humans ; Orexin Receptor Antagonists ; Disease Susceptibility ; Violence ; Suicide ; World Health Organization ; Orexins
    Chemische Substanzen Orexin Receptor Antagonists ; Orexins
    Sprache Englisch
    Erscheinungsdatum 2023-09-27
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 716287-x
    ISSN 1555-2101 ; 0160-6689
    ISSN (online) 1555-2101
    ISSN 0160-6689
    DOI 10.4088/JCP.23br14923
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  10. Artikel ; Online: Activity, cognition, and emotion: Three dimensional pillars of the natural presentations of mood disorders enriched by the "sleep" fourth dimension (ACES).

    Geoffroy, Pierre A / Gottlieb, John

    Bipolar disorders

    2020  Band 22, Heft 6, Seite(n) 631–632

    Mesh-Begriff(e) Bipolar Disorder ; Cognition ; Emotions ; Humans ; Mood Disorders/diagnosis ; Mood Disorders/etiology ; Sleep ; Taurine/analogs & derivatives
    Chemische Substanzen Taurine (1EQV5MLY3D) ; N-(2-acetamido)-2-aminoethanesulfonic acid (7365-82-4)
    Sprache Englisch
    Erscheinungsdatum 2020-06-28
    Erscheinungsland Denmark
    Dokumenttyp Journal Article ; Comment
    ZDB-ID 1472242-2
    ISSN 1399-5618 ; 1398-5647
    ISSN (online) 1399-5618
    ISSN 1398-5647
    DOI 10.1111/bdi.12957
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