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  1. Article ; Online: Beware of Superficial Thrombophlebitis Mimicking a Foreign Body.

    Georgiades, Fanourios / Najem, Mojahid

    European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

    2023  Volume 65, Issue 6, Page(s) 849

    MeSH term(s) Humans ; Thrombophlebitis/diagnostic imaging ; Foreign Bodies/diagnostic imaging ; Foreign Bodies/surgery
    Language English
    Publishing date 2023-03-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 1225869-6
    ISSN 1532-2165 ; 1078-5884
    ISSN (online) 1532-2165
    ISSN 1078-5884
    DOI 10.1016/j.ejvs.2023.03.031
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A Simple and Quick Solution to the Retained Traumatic Urethral Catheter.

    Georgiades, F / Bakewell, R / Tsiotras, A

    Urology

    2020  Volume 141, Page(s) e39–e40

    Abstract: A misplaced urinary catheter within the bulbar urethra in a medically complex patient could not be removed due to an undeflatable balloon. Simple bedside measures including flexible cystoscopy were unsuccessful in deflating this. Here we describe a ... ...

    Abstract A misplaced urinary catheter within the bulbar urethra in a medically complex patient could not be removed due to an undeflatable balloon. Simple bedside measures including flexible cystoscopy were unsuccessful in deflating this. Here we describe a simple and quick solution to this stressful situation using a transperineal ultrasound guided puncture. This method should be considered when the retained traumatic catheter lies distal to the prostate gland.
    MeSH term(s) Aged ; Device Removal/methods ; Foreign Bodies/complications ; Foreign Bodies/therapy ; Humans ; Male ; Time Factors ; Urethra/injuries ; Urinary Catheters/adverse effects
    Language English
    Publishing date 2020-04-17
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 192062-5
    ISSN 1527-9995 ; 0090-4295
    ISSN (online) 1527-9995
    ISSN 0090-4295
    DOI 10.1016/j.urology.2020.04.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Irreversible electroporation in renal tumours: A systematic review of safety and early oncological outcomes.

    Hilton, Aidan / Kourounis, Georgios / Georgiades, Fanourios

    Urologia

    2022  Volume 89, Issue 3, Page(s) 329–337

    Abstract: We review the safety and early oncological outcomes of irreversible electroporation (IRE), a novel non-thermal ablation technique, in small renal masses (SRMs). Following PROSPERO registration (CRD42020197943), a systematic search of MEDLINE, EMBASE and ... ...

    Abstract We review the safety and early oncological outcomes of irreversible electroporation (IRE), a novel non-thermal ablation technique, in small renal masses (SRMs). Following PROSPERO registration (CRD42020197943), a systematic search of MEDLINE, EMBASE and SCOPUS databases according to PRISMA guidelines was performed. Critical appraisal of the included studies was performed using the Newcastle-Ottawa Scale. Of 224 articles screened, 10 met the inclusion criteria. In total, 83 patients were identified. Except for one cohort study (
    MeSH term(s) Ablation Techniques/adverse effects ; Ablation Techniques/methods ; Cohort Studies ; Electroporation/methods ; Humans ; Kidney Neoplasms/etiology ; Kidney Neoplasms/surgery ; Treatment Outcome
    Language English
    Publishing date 2022-02-10
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ZDB-ID 204043-8
    ISSN 1724-6075 ; 0376-0057 ; 0391-5603
    ISSN (online) 1724-6075
    ISSN 0376-0057 ; 0391-5603
    DOI 10.1177/03915603221077590
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Trans-urethral bladder suture in female patients: Not a tour de force but a quick and realistic answer to complex situations.

    Georgiades, Fanourios / Kouriefs, Chryssanthos / Makanjuola, Jonathan / Grange, Philippe

    Urologia

    2021  Volume 89, Issue 2, Page(s) 231–234

    Abstract: Introduction: Trans-urethral bladder surgery has gained popularity in the fields of electro-resection and laser lithotripsy, with endoscopic suturing being overlooked. Bladder defect closure using a pure trans-urethral suturing technique can provide a ... ...

    Abstract Introduction: Trans-urethral bladder surgery has gained popularity in the fields of electro-resection and laser lithotripsy, with endoscopic suturing being overlooked. Bladder defect closure using a pure trans-urethral suturing technique can provide a quick and effective solution in situations where conventional management options are not feasible.
    Methods: Here we describe this innovative novel technique developed by our group that was used to treat two different cases with bladder perforation at two different institutions. We used a 5 mm laparoscopic port with gas insufflation and a laparoscopic needle holder trans-urethrally to achieve defect closure with a monofilament 2/0 monocryl mattress suture on a small 22 mm needle.
    Results: The defects were successfully closed without any intraoperative complications. Average operative time for the technique was 18 min with minimal blood loss. Bladder closure was sustained at a median follow-up of 2 years for one of these cases.
    Conclusions: We claim that transurethral bladder suturing is quick, safe in expert hands and provides an effective option where the clinical condition/situation of the patient warrants a minimally invasive surgery approach.
    MeSH term(s) Female ; Humans ; Laparoscopy/methods ; Male ; Suture Techniques ; Sutures ; Treatment Outcome ; Urinary Bladder/surgery ; Urinary Bladder Diseases/surgery ; Urologic Surgical Procedures
    Language English
    Publishing date 2021-03-16
    Publishing country United States
    Document type Journal Article
    ZDB-ID 204043-8
    ISSN 1724-6075 ; 0376-0057 ; 0391-5603
    ISSN (online) 1724-6075
    ISSN 0376-0057 ; 0391-5603
    DOI 10.1177/03915603211001168
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Systematic review and meta-analysis of early vs late interval laparoscopic cholecystectomy following percutaneous cholecystostomy.

    Kourounis, Georgios / Rooke, Zoë C / McGuigan, Mark / Georgiades, Fanourios

    HPB : the official journal of the International Hepato Pancreato Biliary Association

    2022  Volume 24, Issue 9, Page(s) 1405–1415

    Abstract: Background: High risk surgical patients with acute cholecystitis are commonly treated with percutaneous cholecystostomy (PTC) drainage. The optimal timing of subsequent interval laparoscopic cholecystectomy (LC) remains unclear.: Methods: Medline, ... ...

    Abstract Background: High risk surgical patients with acute cholecystitis are commonly treated with percutaneous cholecystostomy (PTC) drainage. The optimal timing of subsequent interval laparoscopic cholecystectomy (LC) remains unclear.
    Methods: Medline, EMBASE, and Scopus were searched to identify studies published between 01/01/2000 and 31/12/2020, reporting on interval LC outcomes in patients initially treated by PTC. Early and late interval LC were defined as <30 and ≥ 30 days respectively. The Methodological Index for Nonrandomized Studies was used for quality assessment. Meta-analysis of proportions was conducted using a random-effects model.
    Results: A total of 512 studies were screened, 41 met the inclusion criteria. There were 22 studies in both early and late interval LC groups, with 3 included studies reporting both early and late groups. Following quality assessment, 29 studies were included in the meta-analysis. There were no significant differences between early and late interval LC in terms of conversion rates (7.2% vs 8.3%, p = 0.854), 90-day morbidity (12.8% vs 15.9%, p = 0.496), and 90-day mortality (0.25% vs 0.32%, p = 0.704). Heterogeneity was significant (I
    Conclusion: Current evidence of interval LC within or beyond 30 days demonstrates no significant impact on outcomes. Patient factors, clinical experience, and hospital facilities may prove more important predictors.
    MeSH term(s) Cholecystectomy, Laparoscopic/adverse effects ; Cholecystitis, Acute/diagnosis ; Cholecystitis, Acute/surgery ; Cholecystostomy/adverse effects ; Humans ; Morbidity ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2022-04-06
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Review ; Systematic Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2131251-5
    ISSN 1477-2574 ; 1365-182X
    ISSN (online) 1477-2574
    ISSN 1365-182X
    DOI 10.1016/j.hpb.2022.03.016
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Robotic assisted laparoscopic radical prostatectomy following open trans-vesical adenomectomy: A single centre experience and review of the literature.

    Georgiades, Fanourios / Konstantinou, Kostas / Kouriefs, Chryssanthos

    Urologia

    2020  Volume 88, Issue 2, Page(s) 135–139

    Abstract: Introduction: Robotic assisted laparoscopic radical prostatectomy (RALRP) following endoscopic resection of the prostate is known to be feasible with good outcomes. However, the literature evidence is limited on the feasibility and outcomes of RALRP ... ...

    Abstract Introduction: Robotic assisted laparoscopic radical prostatectomy (RALRP) following endoscopic resection of the prostate is known to be feasible with good outcomes. However, the literature evidence is limited on the feasibility and outcomes of RALRP following open prostatic surgery. In this study, our aim was to report our experience with RALRP in patients who had undergone trans-vesical adenomectomy of the prostate in the past.
    Patients and methods: We reviewed our prospectively maintained database of men treated with RALRP at our institution to identify patients with previous history of open suprapubic trans-vesical adenomectomy, between 2016 and 2020. Data were collected on demographic information, interventions, oncological outcomes and follow-up.
    Results: Out of 362 patients, four individuals were identified that had previous open suprapubic trans-vesical adenomectomy. The mean age was 71 years with a mean pre-operative prostate specific antigen (PSA) of 11.35 ng/ml, and an average of 10 years after their trans-vesical adenomectomy. The mean console time was 119 min with an average estimated blood loss of 137.5 ml and 75% underwent lymphadenectomy. Post-operatively, all patients were discharged after 1 day with their urinary catheters removed at 7 days post-op. For one of the patients, a urine leak was identified, and his pelvic drain was removed at 5 days instead of 1 day as for the other three patients. No other complications were noted within 30 days. The average prostate weight was 54.7 g with all specimens being T3a R0. At 6 weeks follow-up, PSA was undetectable, three patients reported full continence and 1 was using two pads/day.
    Conclusion: RALRP following previous open trans-vesical prostatectomy is feasible and safe with excellent oncological outcomes. They are, however, more challenging and cumbersome with increased console time.
    MeSH term(s) Aged ; Humans ; Laparoscopy ; Male ; Prospective Studies ; Prostatectomy/methods ; Prostatic Hyperplasia/surgery ; Robotic Surgical Procedures ; Urinary Bladder
    Language English
    Publishing date 2020-12-10
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 204043-8
    ISSN 1724-6075 ; 0376-0057 ; 0391-5603
    ISSN (online) 1724-6075
    ISSN 0376-0057 ; 0391-5603
    DOI 10.1177/0391560320979858
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Outpatient ureteric stent removal following kidney transplantation.

    Georgiades, F / Silva, A N S / Purohit, K / King, S / Torpey, N / Saeb-Parsy, K / Pettigrew, G J / Rouhani, F J

    The British journal of surgery

    2021  Volume 109, Issue 2, Page(s) 152–154

    MeSH term(s) Adolescent ; Adult ; Aged ; Ambulatory Surgical Procedures/adverse effects ; Ambulatory Surgical Procedures/economics ; Ambulatory Surgical Procedures/methods ; Cost-Benefit Analysis ; Cystoscopy/adverse effects ; Cystoscopy/economics ; Cystoscopy/methods ; Device Removal/adverse effects ; Device Removal/economics ; Device Removal/methods ; Feasibility Studies ; Female ; Hospital Costs ; Humans ; Kidney Transplantation ; Male ; Middle Aged ; Operating Rooms/economics ; Postoperative Care/adverse effects ; Postoperative Care/economics ; Postoperative Care/methods ; Postoperative Complications ; Retrospective Studies ; Stents ; Ureter ; Young Adult
    Language English
    Publishing date 2021-08-25
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2985-3
    ISSN 1365-2168 ; 0263-1202 ; 0007-1323 ; 1355-7688
    ISSN (online) 1365-2168
    ISSN 0263-1202 ; 0007-1323 ; 1355-7688
    DOI 10.1093/bjs/znab223
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: HoLEP for acute and non-neurogenic chronic urinary retention: how effective is it?

    Aho, Tevita / Finch, William / Jefferson, Philippa / Suraparaju, Lokesh / Georgiades, Fanourios

    World journal of urology

    2021  Volume 39, Issue 7, Page(s) 2355–2361

    Abstract: Purpose: To determine catheter status within 3 months of holmium laser enucleation of the prostate (HoLEP) for acute and non-neurogenic chronic urinary retention (AUR and NNCUR), to compare short-term outcomes of HoLEP for urinary retention (UR) versus ... ...

    Abstract Purpose: To determine catheter status within 3 months of holmium laser enucleation of the prostate (HoLEP) for acute and non-neurogenic chronic urinary retention (AUR and NNCUR), to compare short-term outcomes of HoLEP for urinary retention (UR) versus lower urinary tract symptoms (LUTS), and to report long-term serum creatinine (SC) after HoLEP for high-pressure chronic urinary retention (HPCUR).
    Methods: A prospectively maintained database of the first 500 consecutive HoLEP cases performed under the care of a single surgeon was analysed retrospectively. Urodynamic studies (UDS) did not play a role in the decision making process for those with UR. NNCUR was defined as painless, with post-void residual volume (PVR) greater than 300 ml in men able to void and initial catheter drainage > 1000 ml in men unable to void.
    Results: 280/500 (56%) were in UR: AUR (195), and NNCUR (85) including 22 with HPCUR. The UR cohort were older with higher enucleated tissue weight [median (IQR); 72 years (66-79 year) and 56 g (29.8-86.3 g)], than the LUTS cohort [70 years (64-75 year) and 38 g (18-67 g)] (p < 0.001). 98.9% with AUR and 98.8% with NNCUR were catheter-free 3 months after HoLEP. There were no significant differences in transfusion rates, hospital stay, or time to first trial without catheter (TWOC) between the LUTS and UR cohorts, nor in international prostate symptom score and quality of life scores, maximum urinary flow rate, post void residual volume or urinary incontinence at 3 months. Patients with NNCUR were less likely to pass their first TWOC (58.8%) than those with AUR (84.6%) or LUTS (87.7%), p < 0.001. None with HPCUR had a clinically significant deterioration in SC at a median of 60 months (IQR 36-82 months).
    Conclusion: HoLEP has 3-month catheter-free rates in excess of 98.5% for AUR and NNCUR in patients not pre-selected by UDS. First TWOC is significantly more likely to fail after HoLEP for NNCUR than AUR or LUTS. HoLEP is a durable treatment for HPCUR and there is no need to monitor renal function to detect recurrence.
    MeSH term(s) Acute Disease ; Aged ; Chronic Disease ; Humans ; Lasers, Solid-State/therapeutic use ; Lower Urinary Tract Symptoms/surgery ; Male ; Middle Aged ; Retrospective Studies ; Time Factors ; Treatment Outcome ; Urinary Retention/surgery
    Language English
    Publishing date 2021-03-24
    Publishing country Germany
    Document type Comparative Study ; Journal Article
    ZDB-ID 380333-8
    ISSN 1433-8726 ; 0724-4983
    ISSN (online) 1433-8726
    ISSN 0724-4983
    DOI 10.1007/s00345-021-03657-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Percutaneous hook wire assistance during laparoscopic excision of an intrarenal mass.

    Kouriefs, C / Georgiades, F / Michaelides, M / Ioannides, K / Kouriefs, A / Grange, P

    Annals of the Royal College of Surgeons of England

    2019  Volume 101, Issue 6, Page(s) e136–e138

    Abstract: Completely endophytic renal tumours pose challenges in laparoscopic nephron-sparing tumour excisions, with the use of intraoperative imaging techniques (e.g. ultrasound) being crucial when managing such tumours. The use of a percutaneous hookwire for ... ...

    Abstract Completely endophytic renal tumours pose challenges in laparoscopic nephron-sparing tumour excisions, with the use of intraoperative imaging techniques (e.g. ultrasound) being crucial when managing such tumours. The use of a percutaneous hookwire for tumour localisations are in use in several other surgical fields, such as breast surgery. An asymptomatic 52-year-old man presented with an incidental small right sided solid 33-mm interpolar renal mass identified on computed tomography. A guided insertion of a percutaneous localisation wire was carried out prior to a laparoscopic partial nephrectomy to assist in intraoperative tumour landmark/margins identification. Operative time was 210 minutes with zero ischaemia time, with an estimated blood loss of 200 ml. No perioperative complications were observed and the patient was discharged two days postoperatively. Histology revealed the mass to be a Fuhrman grade 2 clear-cell carcinoma with a 2-mm clear surgical margin. The patient remained free of recurrence at 16 months of follow-up. We have reported our first experience of wire localisation prior to laparoscopic partial nephrectomy for an intrarenal mass, which to our knowledge could be the first of its kind in renal surgery. Percutaneous wire localisation of endophytic renal tumours is potentially safe and effective and can allow nephron-sparing surgery where laparoscopic ultrasound is not available. Longer-term and further evidence should be encouraged.
    MeSH term(s) Carcinoma, Renal Cell/diagnostic imaging ; Carcinoma, Renal Cell/surgery ; Humans ; Kidney Neoplasms/diagnostic imaging ; Kidney Neoplasms/surgery ; Laparoscopy/instrumentation ; Laparoscopy/methods ; Male ; Middle Aged ; Nephrectomy/instrumentation ; Nephrectomy/methods ; Radiography, Interventional/instrumentation ; Radiography, Interventional/methods ; Surgical Instruments ; Tomography, X-Ray Computed
    Language English
    Publishing date 2019-06-03
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 80044-2
    ISSN 1478-7083 ; 0035-8843
    ISSN (online) 1478-7083
    ISSN 0035-8843
    DOI 10.1308/rcsann.2019.0056
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: A call for HoLEP: AEEP for mega-prostates (≥ 200 cc).

    Boxall, Nicholas E / Georgiades, Fanourios / Miah, Saiful / Dragos, Laurian / Armitage, James / Aho, Tevita F

    World journal of urology

    2021  Volume 39, Issue 7, Page(s) 2347–2353

    Abstract: Purpose: To evaluate the efficiency and efficacy of HoLEP, and methods of tissue retrieval, in patients with prostate volume (PV) ≥ 200 cc (Group 1) and to compare these to patients with PV 80-199 cc (Group 2).: Methods: A database of all cases ... ...

    Abstract Purpose: To evaluate the efficiency and efficacy of HoLEP, and methods of tissue retrieval, in patients with prostate volume (PV) ≥ 200 cc (Group 1) and to compare these to patients with PV 80-199 cc (Group 2).
    Methods: A database of all cases performed under the care of two surgeons at a tertiary HoLEP centre was reviewed.
    Results: 157 patients with PV ≥ 200 cc were compared to 157 of the most recent consecutive cases with PV 80-199 cc. Median (IQR) enucleation efficiency was greater in Group 1 [2.8 g/min (2.2-3.5)] than Group 2 [2.1 g/min (1.6-2.5), p < 0.001]. Morcellation efficiency did not differ significantly. Cystotomy was required for tissue retrieval in Group 1 only (5.7%). Decrease in serum haemoglobin (Hb) was greater in Group 1 (19 g/l (30-8) vs 12 (18-3.5), p < 0.001) with a transfusion rate of 4.5% vs 1.3%, respectively (p = 0.104). Length of stay was longer in Group 1 than Group 2 (1 day (1-2) vs 1 (1-1), p < 0.001). There were no significant differences between groups in: time to and success of first trial without catheter, pre- and post-operative IPSS, Qmax and PVR, and 3 month catheter-free and urinary incontinence rates.
    Conclusion: HoLEP outcomes are largely PV-independent even when PV is ≥ 200 cc, although length of stay and reduction in Hb are greater in this group. Alternatives to pure morcellation, such as cystotomy and resection of nodules, are more likely to be necessary with PV ≥ 200 cc.
    MeSH term(s) Aged ; Humans ; Lasers, Solid-State/therapeutic use ; Male ; Organ Size ; Prostate/pathology ; Prostatectomy/methods ; Prostatic Hyperplasia/pathology ; Prostatic Hyperplasia/surgery ; Retrospective Studies
    Language English
    Publishing date 2021-05-12
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 380333-8
    ISSN 1433-8726 ; 0724-4983
    ISSN (online) 1433-8726
    ISSN 0724-4983
    DOI 10.1007/s00345-021-03708-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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