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Article ; Online: Beware of Superficial Thrombophlebitis Mimicking a Foreign Body.

Georgiades, Fanourios / Najem, Mojahid

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery

2023 Volume 65, Issue 6, Page(s) 849

MeSH term(s)	Humans ; Thrombophlebitis/diagnostic imaging ; Foreign Bodies/diagnostic imaging ; Foreign Bodies/surgery
Language	English
Publishing date	2023-03-21
Publishing country	England
Document type	Journal Article
ZDB-ID	1225869-6
ISSN	1532-2165 ; 1078-5884
ISSN (online)	1532-2165
ISSN	1078-5884
DOI	10.1016/j.ejvs.2023.03.031
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Zs.A 2283: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (2.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Irreversible electroporation in renal tumours: A systematic review of safety and early oncological outcomes.

Hilton, Aidan / Kourounis, Georgios / Georgiades, Fanourios

Urologia

2022 Volume 89, Issue 3, Page(s) 329–337

Abstract: We review the safety and early oncological outcomes of irreversible electroporation (IRE), a novel non-thermal ablation technique, in small renal masses (SRMs). Following PROSPERO registration (CRD42020197943), a systematic search of MEDLINE, EMBASE and ... ...

Abstract	We review the safety and early oncological outcomes of irreversible electroporation (IRE), a novel non-thermal ablation technique, in small renal masses (SRMs). Following PROSPERO registration (CRD42020197943), a systematic search of MEDLINE, EMBASE and SCOPUS databases according to PRISMA guidelines was performed. Critical appraisal of the included studies was performed using the Newcastle-Ottawa Scale. Of 224 articles screened, 10 met the inclusion criteria. In total, 83 patients were identified. Except for one cohort study (
MeSH term(s)	Ablation Techniques/adverse effects ; Ablation Techniques/methods ; Cohort Studies ; Electroporation/methods ; Humans ; Kidney Neoplasms/etiology ; Kidney Neoplasms/surgery ; Treatment Outcome
Language	English
Publishing date	2022-02-10
Publishing country	United States
Document type	Journal Article ; Systematic Review
ZDB-ID	204043-8
ISSN	1724-6075 ; 0376-0057 ; 0391-5603
ISSN (online)	1724-6075
ISSN	0376-0057 ; 0391-5603
DOI	10.1177/03915603221077590
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Zs.B 891: Show issues

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Article ; Online: Trans-urethral bladder suture in female patients: Not a tour de force but a quick and realistic answer to complex situations.

Georgiades, Fanourios / Kouriefs, Chryssanthos / Makanjuola, Jonathan / Grange, Philippe

Urologia

2021 Volume 89, Issue 2, Page(s) 231–234

Abstract: Introduction: Trans-urethral bladder surgery has gained popularity in the fields of electro-resection and laser lithotripsy, with endoscopic suturing being overlooked. Bladder defect closure using a pure trans-urethral suturing technique can provide a ... ...

Abstract	Introduction: Trans-urethral bladder surgery has gained popularity in the fields of electro-resection and laser lithotripsy, with endoscopic suturing being overlooked. Bladder defect closure using a pure trans-urethral suturing technique can provide a quick and effective solution in situations where conventional management options are not feasible. Methods: Here we describe this innovative novel technique developed by our group that was used to treat two different cases with bladder perforation at two different institutions. We used a 5 mm laparoscopic port with gas insufflation and a laparoscopic needle holder trans-urethrally to achieve defect closure with a monofilament 2/0 monocryl mattress suture on a small 22 mm needle. Results: The defects were successfully closed without any intraoperative complications. Average operative time for the technique was 18 min with minimal blood loss. Bladder closure was sustained at a median follow-up of 2 years for one of these cases. Conclusions: We claim that transurethral bladder suturing is quick, safe in expert hands and provides an effective option where the clinical condition/situation of the patient warrants a minimally invasive surgery approach.
MeSH term(s)	Female ; Humans ; Laparoscopy/methods ; Male ; Suture Techniques ; Sutures ; Treatment Outcome ; Urinary Bladder/surgery ; Urinary Bladder Diseases/surgery ; Urologic Surgical Procedures
Language	English
Publishing date	2021-03-16
Publishing country	United States
Document type	Journal Article
ZDB-ID	204043-8
ISSN	1724-6075 ; 0376-0057 ; 0391-5603
ISSN (online)	1724-6075
ISSN	0376-0057 ; 0391-5603
DOI	10.1177/03915603211001168
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Article ; Online: Systematic review and meta-analysis of early vs late interval laparoscopic cholecystectomy following percutaneous cholecystostomy.

Kourounis, Georgios / Rooke, Zoë C / McGuigan, Mark / Georgiades, Fanourios

HPB : the official journal of the International Hepato Pancreato Biliary Association

2022 Volume 24, Issue 9, Page(s) 1405–1415

Abstract: Background: High risk surgical patients with acute cholecystitis are commonly treated with percutaneous cholecystostomy (PTC) drainage. The optimal timing of subsequent interval laparoscopic cholecystectomy (LC) remains unclear.: Methods: Medline, ... ...

Abstract	Background: High risk surgical patients with acute cholecystitis are commonly treated with percutaneous cholecystostomy (PTC) drainage. The optimal timing of subsequent interval laparoscopic cholecystectomy (LC) remains unclear. Methods: Medline, EMBASE, and Scopus were searched to identify studies published between 01/01/2000 and 31/12/2020, reporting on interval LC outcomes in patients initially treated by PTC. Early and late interval LC were defined as <30 and ≥ 30 days respectively. The Methodological Index for Nonrandomized Studies was used for quality assessment. Meta-analysis of proportions was conducted using a random-effects model. Results: A total of 512 studies were screened, 41 met the inclusion criteria. There were 22 studies in both early and late interval LC groups, with 3 included studies reporting both early and late groups. Following quality assessment, 29 studies were included in the meta-analysis. There were no significant differences between early and late interval LC in terms of conversion rates (7.2% vs 8.3%, p = 0.854), 90-day morbidity (12.8% vs 15.9%, p = 0.496), and 90-day mortality (0.25% vs 0.32%, p = 0.704). Heterogeneity was significant (I Conclusion: Current evidence of interval LC within or beyond 30 days demonstrates no significant impact on outcomes. Patient factors, clinical experience, and hospital facilities may prove more important predictors.
MeSH term(s)	Cholecystectomy, Laparoscopic/adverse effects ; Cholecystitis, Acute/diagnosis ; Cholecystitis, Acute/surgery ; Cholecystostomy/adverse effects ; Humans ; Morbidity ; Retrospective Studies ; Treatment Outcome
Language	English
Publishing date	2022-04-06
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Review ; Systematic Review ; Research Support, Non-U.S. Gov't
ZDB-ID	2131251-5
ISSN	1477-2574 ; 1365-182X
ISSN (online)	1477-2574
ISSN	1365-182X
DOI	10.1016/j.hpb.2022.03.016
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Zs.A 6326: Show issues

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Article ; Online: Robotic assisted laparoscopic radical prostatectomy following open trans-vesical adenomectomy: A single centre experience and review of the literature.

Georgiades, Fanourios / Konstantinou, Kostas / Kouriefs, Chryssanthos

Urologia

2020 Volume 88, Issue 2, Page(s) 135–139

Abstract: Introduction: Robotic assisted laparoscopic radical prostatectomy (RALRP) following endoscopic resection of the prostate is known to be feasible with good outcomes. However, the literature evidence is limited on the feasibility and outcomes of RALRP ... ...

Abstract	Introduction: Robotic assisted laparoscopic radical prostatectomy (RALRP) following endoscopic resection of the prostate is known to be feasible with good outcomes. However, the literature evidence is limited on the feasibility and outcomes of RALRP following open prostatic surgery. In this study, our aim was to report our experience with RALRP in patients who had undergone trans-vesical adenomectomy of the prostate in the past. Patients and methods: We reviewed our prospectively maintained database of men treated with RALRP at our institution to identify patients with previous history of open suprapubic trans-vesical adenomectomy, between 2016 and 2020. Data were collected on demographic information, interventions, oncological outcomes and follow-up. Results: Out of 362 patients, four individuals were identified that had previous open suprapubic trans-vesical adenomectomy. The mean age was 71 years with a mean pre-operative prostate specific antigen (PSA) of 11.35 ng/ml, and an average of 10 years after their trans-vesical adenomectomy. The mean console time was 119 min with an average estimated blood loss of 137.5 ml and 75% underwent lymphadenectomy. Post-operatively, all patients were discharged after 1 day with their urinary catheters removed at 7 days post-op. For one of the patients, a urine leak was identified, and his pelvic drain was removed at 5 days instead of 1 day as for the other three patients. No other complications were noted within 30 days. The average prostate weight was 54.7 g with all specimens being T3a R0. At 6 weeks follow-up, PSA was undetectable, three patients reported full continence and 1 was using two pads/day. Conclusion: RALRP following previous open trans-vesical prostatectomy is feasible and safe with excellent oncological outcomes. They are, however, more challenging and cumbersome with increased console time.
MeSH term(s)	Aged ; Humans ; Laparoscopy ; Male ; Prospective Studies ; Prostatectomy/methods ; Prostatic Hyperplasia/surgery ; Robotic Surgical Procedures ; Urinary Bladder
Language	English
Publishing date	2020-12-10
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	204043-8
ISSN	1724-6075 ; 0376-0057 ; 0391-5603
ISSN (online)	1724-6075
ISSN	0376-0057 ; 0391-5603
DOI	10.1177/0391560320979858
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Zs.B 891: Show issues

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Article ; Online: HoLEP for acute and non-neurogenic chronic urinary retention: how effective is it?

Aho, Tevita / Finch, William / Jefferson, Philippa / Suraparaju, Lokesh / Georgiades, Fanourios

World journal of urology

2021 Volume 39, Issue 7, Page(s) 2355–2361

Abstract: Purpose: To determine catheter status within 3 months of holmium laser enucleation of the prostate (HoLEP) for acute and non-neurogenic chronic urinary retention (AUR and NNCUR), to compare short-term outcomes of HoLEP for urinary retention (UR) versus ... ...

Abstract	Purpose: To determine catheter status within 3 months of holmium laser enucleation of the prostate (HoLEP) for acute and non-neurogenic chronic urinary retention (AUR and NNCUR), to compare short-term outcomes of HoLEP for urinary retention (UR) versus lower urinary tract symptoms (LUTS), and to report long-term serum creatinine (SC) after HoLEP for high-pressure chronic urinary retention (HPCUR). Methods: A prospectively maintained database of the first 500 consecutive HoLEP cases performed under the care of a single surgeon was analysed retrospectively. Urodynamic studies (UDS) did not play a role in the decision making process for those with UR. NNCUR was defined as painless, with post-void residual volume (PVR) greater than 300 ml in men able to void and initial catheter drainage > 1000 ml in men unable to void. Results: 280/500 (56%) were in UR: AUR (195), and NNCUR (85) including 22 with HPCUR. The UR cohort were older with higher enucleated tissue weight [median (IQR); 72 years (66-79 year) and 56 g (29.8-86.3 g)], than the LUTS cohort [70 years (64-75 year) and 38 g (18-67 g)] (p < 0.001). 98.9% with AUR and 98.8% with NNCUR were catheter-free 3 months after HoLEP. There were no significant differences in transfusion rates, hospital stay, or time to first trial without catheter (TWOC) between the LUTS and UR cohorts, nor in international prostate symptom score and quality of life scores, maximum urinary flow rate, post void residual volume or urinary incontinence at 3 months. Patients with NNCUR were less likely to pass their first TWOC (58.8%) than those with AUR (84.6%) or LUTS (87.7%), p < 0.001. None with HPCUR had a clinically significant deterioration in SC at a median of 60 months (IQR 36-82 months). Conclusion: HoLEP has 3-month catheter-free rates in excess of 98.5% for AUR and NNCUR in patients not pre-selected by UDS. First TWOC is significantly more likely to fail after HoLEP for NNCUR than AUR or LUTS. HoLEP is a durable treatment for HPCUR and there is no need to monitor renal function to detect recurrence.
MeSH term(s)	Acute Disease ; Aged ; Chronic Disease ; Humans ; Lasers, Solid-State/therapeutic use ; Lower Urinary Tract Symptoms/surgery ; Male ; Middle Aged ; Retrospective Studies ; Time Factors ; Treatment Outcome ; Urinary Retention/surgery
Language	English
Publishing date	2021-03-24
Publishing country	Germany
Document type	Comparative Study ; Journal Article
ZDB-ID	380333-8
ISSN	1433-8726 ; 0724-4983
ISSN (online)	1433-8726
ISSN	0724-4983
DOI	10.1007/s00345-021-03657-x
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Zs.A 1832: Show issues

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Article ; Online: A call for HoLEP: AEEP for mega-prostates (≥ 200 cc).

Boxall, Nicholas E / Georgiades, Fanourios / Miah, Saiful / Dragos, Laurian / Armitage, James / Aho, Tevita F

World journal of urology

2021 Volume 39, Issue 7, Page(s) 2347–2353

Abstract: Purpose: To evaluate the efficiency and efficacy of HoLEP, and methods of tissue retrieval, in patients with prostate volume (PV) ≥ 200 cc (Group 1) and to compare these to patients with PV 80-199 cc (Group 2).: Methods: A database of all cases ... ...

Abstract	Purpose: To evaluate the efficiency and efficacy of HoLEP, and methods of tissue retrieval, in patients with prostate volume (PV) ≥ 200 cc (Group 1) and to compare these to patients with PV 80-199 cc (Group 2). Methods: A database of all cases performed under the care of two surgeons at a tertiary HoLEP centre was reviewed. Results: 157 patients with PV ≥ 200 cc were compared to 157 of the most recent consecutive cases with PV 80-199 cc. Median (IQR) enucleation efficiency was greater in Group 1 [2.8 g/min (2.2-3.5)] than Group 2 [2.1 g/min (1.6-2.5), p < 0.001]. Morcellation efficiency did not differ significantly. Cystotomy was required for tissue retrieval in Group 1 only (5.7%). Decrease in serum haemoglobin (Hb) was greater in Group 1 (19 g/l (30-8) vs 12 (18-3.5), p < 0.001) with a transfusion rate of 4.5% vs 1.3%, respectively (p = 0.104). Length of stay was longer in Group 1 than Group 2 (1 day (1-2) vs 1 (1-1), p < 0.001). There were no significant differences between groups in: time to and success of first trial without catheter, pre- and post-operative IPSS, Qmax and PVR, and 3 month catheter-free and urinary incontinence rates. Conclusion: HoLEP outcomes are largely PV-independent even when PV is ≥ 200 cc, although length of stay and reduction in Hb are greater in this group. Alternatives to pure morcellation, such as cystotomy and resection of nodules, are more likely to be necessary with PV ≥ 200 cc.
MeSH term(s)	Aged ; Humans ; Lasers, Solid-State/therapeutic use ; Male ; Organ Size ; Prostate/pathology ; Prostatectomy/methods ; Prostatic Hyperplasia/pathology ; Prostatic Hyperplasia/surgery ; Retrospective Studies
Language	English
Publishing date	2021-05-12
Publishing country	Germany
Document type	Journal Article
ZDB-ID	380333-8
ISSN	1433-8726 ; 0724-4983
ISSN (online)	1433-8726
ISSN	0724-4983
DOI	10.1007/s00345-021-03708-3
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Article ; Online: Optical diagnosis of colorectal polyps using convolutional neural networks.

Kader, Rawen / Hadjinicolaou, Andreas V / Georgiades, Fanourios / Stoyanov, Danail / Lovat, Laurence B

World journal of gastroenterology

2021 Volume 27, Issue 35, Page(s) 5908–5918

Abstract: Colonoscopy remains the gold standard investigation for colorectal cancer screening as it offers the opportunity to both detect and resect pre-malignant and neoplastic polyps. Although technologies for image-enhanced endoscopy are widely available, ... ...

Abstract	Colonoscopy remains the gold standard investigation for colorectal cancer screening as it offers the opportunity to both detect and resect pre-malignant and neoplastic polyps. Although technologies for image-enhanced endoscopy are widely available, optical diagnosis has not been incorporated into routine clinical practice, mainly due to significant inter-operator variability. In recent years, there has been a growing number of studies demonstrating the potential of convolutional neural networks (CNN) to enhance optical diagnosis of polyps. Data suggest that the use of CNNs might mitigate the inter-operator variability amongst endoscopists, potentially enabling a "resect and discard" or "leave in" strategy to be adopted in real-time. This would have significant financial benefits for healthcare systems, avoid unnecessary polypectomies of non-neoplastic polyps and improve the efficiency of colonoscopy. Here, we review advances in CNN for the optical diagnosis of colorectal polyps, current limitations and future directions.
MeSH term(s)	Colonic Polyps/diagnostic imaging ; Colonic Polyps/surgery ; Colonoscopy ; Colorectal Neoplasms/diagnostic imaging ; Early Detection of Cancer ; Humans ; Neural Networks, Computer
Language	English
Publishing date	2021-09-12
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	2185929-2
ISSN	2219-2840 ; 1007-9327
ISSN (online)	2219-2840
ISSN	1007-9327
DOI	10.3748/wjg.v27.i35.5908
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Zs.A 6039: Show issues

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Article ; Online: Use of ex vivo normothermic machine perfusion after normothermic regional perfusion to salvage a poorly perfused DCD kidney.

Georgiades, Fanourios / Hosgood, Sarah A / Butler, Andrew J / Nicholson, Michael L

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

2019 Volume 19, Issue 12, Page(s) 3415–3419

Abstract: Normothermic regional perfusion (NRP) and normothermic machine perfusion (NMP) have both been used in the procurement and conditioning of abdominal organs from donation after circulatory death donors with reported improved outcomes for the recipients. ... ...

Abstract	Normothermic regional perfusion (NRP) and normothermic machine perfusion (NMP) have both been used in the procurement and conditioning of abdominal organs from donation after circulatory death donors with reported improved outcomes for the recipients. Here, we describe an unusual case of a kidney that underwent NMP after NRP. After 2 hours of abdominal NRP, the intra-abdominal organs were cold flushed in situ. The liver and right kidney were well flushed, but the left kidney was poorly flushed. Further attempts to clear the left kidney by flushing on the backtable were unsuccessful, and the kidney was thought to be unsuitable for transplant. The left kidney then underwent a 1-hour period of NMP using a red cell-based perfusate. During NMP, the kidney met previously described quality assurance criteria for transplant with good global perfusion and adequate renal blood flow and urine production. The kidney was transplanted into a suitable recipient who had slow early graft function but did not require dialysis posttransplant. The recipient was discharged 6 days posttransplant, and the serum creatinine level was 160 μmol/L (1.8 mg/dL) at 2 months posttransplant.
MeSH term(s)	Aged ; Death ; Extracorporeal Circulation/methods ; Humans ; Kidney/blood supply ; Male ; Organ Preservation/methods ; Organ Preservation/standards ; Perfusion/methods ; Tissue Donors/supply & distribution ; Tissue Survival ; Tissue and Organ Procurement/methods
Language	English
Publishing date	2019-08-23
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2060594-8
ISSN	1600-6143 ; 1600-6135
ISSN (online)	1600-6143
ISSN	1600-6135
DOI	10.1111/ajt.15547
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Article ; Online: Preventing conversion to open surgery during laparoscopic donor nephrectomy complicated by bleeding from the aorta.

Georgiades, Fanourios / Kosmoliaptsis, Vasilis / Nicholson, Michael L / Russell, Neil K

Clinical transplantation

2019 Volume 33, Issue 10, Page(s) e13653

MeSH term(s)	Adult ; Aorta/physiopathology ; Conversion to Open Surgery/statistics & numerical data ; Female ; Hemorrhage/prevention & control ; Humans ; Intraoperative Complications/prevention & control ; Kidney Transplantation ; Laparoscopy/methods ; Living Donors/supply & distribution ; Nephrectomy/methods ; Prognosis ; Tissue and Organ Harvesting/methods
Language	English
Publishing date	2019-07-22
Publishing country	Denmark
Document type	Case Reports ; Letter
ZDB-ID	639001-8
ISSN	1399-0012 ; 0902-0063
ISSN (online)	1399-0012
ISSN	0902-0063
DOI	10.1111/ctr.13653
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