Article ; Online: Maternal characteristics and pregnancy outcomes of hospitalized pregnant women with SARS-CoV-2 infection in South Africa: An International Network of Obstetric Survey Systems-based cohort study.
2021 Volume 155, Issue 3, Page(s) 455–465
Abstract: Objective: To describe risk factors and outcomes of pregnant women infected with SARS-CoV-2 admitted to South African healthcare facilities.: Methods: A population-based cohort study was conducted utilizing an amended International Obstetric ... ...
| Abstract | Objective: To describe risk factors and outcomes of pregnant women infected with SARS-CoV-2 admitted to South African healthcare facilities. Methods: A population-based cohort study was conducted utilizing an amended International Obstetric Surveillance System protocol. Data on pregnant women with SARS-CoV-2 infection, hospitalized between April 14, 2020, and November 24, 2020, were analyzed. Results: A total of 36 hospitals submitted data on 673 infected hospitalized pregnant women; 217 (32.2%) were admitted for COVID-19 illness and 456 for other indications. There were 39 deaths with a case fatality rate of 6.3%: 32 (14.7%) deaths occurred in women admitted for COVID-19 illness compared to 7 (1.8%) in women admitted for other indications. Of the women, 106 (15.9%) required critical care. Maternal tuberculosis, but not HIV co-infection or other co-morbidities, was associated with admission for COVID-19 illness. Rates of cesarean delivery did not differ significantly between women admitted for COVID-19 and those admitted for other indications. There were 179 (35.4%) preterm births, 25 (4.7%) stillbirths, 12 (2.3%) neonatal deaths, and 162 (30.8%) neonatal admissions. Neonatal outcomes did not differ significantly from those of infected women admitted for other indications. Conclusion: The maternal mortality rate was high among women admitted with SARS-CoV-2 infection and higher in women admitted primarily for COVID-19 illness with tuberculosis being the only co-morbidity associated with admission. |
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| MeSH term(s) | COVID-19 ; Cohort Studies ; Female ; Humans ; Infant, Newborn ; Infectious Disease Transmission, Vertical ; Pregnancy ; Pregnancy Complications, Infectious/epidemiology ; Pregnancy Outcome/epidemiology ; Pregnant Women ; Premature Birth ; SARS-CoV-2 ; South Africa/epidemiology | ||||||||||
| Language | English | ||||||||||
| Publishing date | 2021-09-16 | ||||||||||
| Publishing country | United States | ||||||||||
| Document type | Journal Article | ||||||||||
| ZDB-ID | 80149-5 | ||||||||||
| ISSN | 1879-3479 ; 0020-7292 | ||||||||||
| ISSN (online) | 1879-3479 | ||||||||||
| ISSN | 0020-7292 | ||||||||||
| DOI | 10.1002/ijgo.13917 | ||||||||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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