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  1. Article ; Online: Burden of Influenza and Respiratory Syncytial Viruses in Suspected COVID-19 Patients: A Cross-Sectional and Meta-Analysis Study.

    Costa, Vivaldo Gomes da / Gomes, Ana Júlia Chaves / Bittar, Cíntia / Geraldini, Dayla Bott / Previdelli da Conceição, Pâmela Jóyce / Cabral, Ágata Silva / Carvalho, Tamara / Biselli, Joice Matos / Provazzi, Paola Jocelan Scarin / Campos, Guilherme Rodrigues Fernandes / Sanches, Paulo Ricardo da Silva / Costa, Paulo Inácio / Nogueira, Maurício Lacerda / Araujo, João Pessoa / Spilki, Fernando Rosado / Calmon, Marília Freitas / Rahal, Paula

    Viruses

    2023  Volume 15, Issue 3

    Abstract: Non-SARS-CoV-2 respiratory viral infections, such as influenza virus (FluV) and human respiratory syncytial virus (RSV), have contributed considerably to the burden of infectious diseases in the non-COVID-19 era. While the rates of co-infection in SARS- ... ...

    Abstract Non-SARS-CoV-2 respiratory viral infections, such as influenza virus (FluV) and human respiratory syncytial virus (RSV), have contributed considerably to the burden of infectious diseases in the non-COVID-19 era. While the rates of co-infection in SARS-CoV-2-positive group (SCPG) patients have been determined, the burden of other respiratory viruses in the SARS-CoV-2-negative group (SCNG) remains unclear. Here, we conducted a cross-sectional study (São José do Rio Preto county, Brazil), and we collected our data using a meta-analysis to evaluate the pooled prevalence of FluV and RSV among SCNG patients. Out of the 901 patients suspected of COVID-19, our molecular results showed positivity of FluV and RSV in the SCNG was 2% (15/733) and 0.27% (2/733), respectively. Co-infection with SARS-CoV-2 and FluV, or RSV, was identified in 1.7% of the patients (3/168). Following our meta-analysis, 28 studies were selected (
    MeSH term(s) Humans ; Coinfection/epidemiology ; COVID-19/epidemiology ; Cross-Sectional Studies ; Influenza, Human/epidemiology ; Pandemics ; Respiratory Syncytial Virus Infections/epidemiology ; Respiratory Syncytial Virus, Human ; SARS-CoV-2
    Language English
    Publishing date 2023-03-01
    Publishing country Switzerland
    Document type Meta-Analysis ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2516098-9
    ISSN 1999-4915 ; 1999-4915
    ISSN (online) 1999-4915
    ISSN 1999-4915
    DOI 10.3390/v15030665
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The Emergence of the New P.4 Lineage of SARS-CoV-2 With Spike L452R Mutation in Brazil.

    Bittar, Cíntia / Possebon, Fábio Sossai / Ullmann, Leila Sabrina / Geraldini, Dayla Bott / da Costa, Vivaldo G / de Almeida, Luiz G P / da S Sanches, Paulo Ricardo / Nascimento-Júnior, Nailton M / Cilli, Eduardo M / Artico Banho, Cecília / Campos, Guilherme R F / Ferreira, Helena Lage / Sacchetto, Lívia / da Silva, Gislaine C D / Parra, Maisa C P / Moraes, Marília M / da Costa, Paulo Inácio / Vasconcelos, Ana Tereza R / Spilki, Fernando Rosado /
    Nogueira, Maurício L / Rahal, Paula / Araujo, João Pessoa

    Frontiers in public health

    2021  Volume 9, Page(s) 745310

    Abstract: The emergence of several SARS-CoV-2 lineages presenting adaptive mutations is a matter of concern worldwide due to their potential ability to increase transmission and/or evade the immune response. While performing epidemiological and genomic ... ...

    Abstract The emergence of several SARS-CoV-2 lineages presenting adaptive mutations is a matter of concern worldwide due to their potential ability to increase transmission and/or evade the immune response. While performing epidemiological and genomic surveillance of SARS-CoV-2 in samples from Porto Ferreira-São Paulo-Brazil, we identified sequences classified by pangolin as B.1.1.28 harboring Spike L452R mutation, in the RBD region. Phylogenetic analysis revealed that these sequences grouped into a monophyletic branch, with others from Brazil, mainly from the state of São Paulo. The sequences had a set of 15 clade defining amino acid mutations, of which six were in the Spike protein. A new lineage was proposed to Pango and it was accepted and designated P.4. In samples from the city of Porto Ferreira, P.4 lineage has been increasing in frequency since it was first detected in March 2021, corresponding to 34.7% of the samples sequenced in June, the second in prevalence after P.1. Also, it is circulating in 30 cities from the state of São Paulo, and it was also detected in one sample from the state of Sergipe and two from the state of Rio de Janeiro. Further studies are needed to understand whether P.4 should be considered a new threat.
    MeSH term(s) Brazil ; COVID-19 ; Humans ; Mutation ; Phylogeny ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus/genetics
    Chemical Substances Spike Glycoprotein, Coronavirus
    Language English
    Publishing date 2021-10-01
    Publishing country Switzerland
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 2711781-9
    ISSN 2296-2565 ; 2296-2565
    ISSN (online) 2296-2565
    ISSN 2296-2565
    DOI 10.3389/fpubh.2021.745310
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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