LIVIVO - Search results -

Search results

Result 1 - 10 of total 45

Search options

Article ; Online: Does leucocyte- and platelet-rich fibrin enhance neurosensory recovery after genioplasty? A double-blind, split-mouth, randomised clinical trial.

Behnia, Parsa / Behnia, Hossein / Ghanbari, Amir Mohammad / Tabrizi, Reza

The British journal of oral & maxillofacial surgery

2023 Volume 61, Issue 8, Page(s) 534–539

Abstract: Neurosensory disturbances (NSD) are common after genioplasty. In this study we aimed to assess the recovery of NSDs with or without leukocyte- and platelet-rich fibrin (L-PRF) following genioplasty. In this double-blind, split-mouth, randomised clinical ... ...

Abstract	Neurosensory disturbances (NSD) are common after genioplasty. In this study we aimed to assess the recovery of NSDs with or without leukocyte- and platelet-rich fibrin (L-PRF) following genioplasty. In this double-blind, split-mouth, randomised clinical trial, L-PRF was applied around the mental nerve at the osteotomy site in genioplasty (treatment side). The contralateral side was considered the control side. Two-point discrimination (TPD) test, brush test, and self-reported NSDs (SR-NSD) were used to determine NSD at one, four, and 12 months after genioplasty. Twenty patients were studied. At one and four months after osteotomy, the mean scores of TPD and SR-NSDs were significantly different between the treatment and control sides (p = 0.04, p = 0.01, respectively). The mean of TPD and SR-NSDs was not statistically different on both sides 12 months after operation (p = 0.05, p = 0.71, respectively). The application of L-PRF may enhance the speed of NSD recovery four months after genioplasty.
Language	English
Publishing date	2023-07-13
Publishing country	Scotland
Document type	Journal Article
ZDB-ID	605685-4
ISSN	1532-1940 ; 0266-4356
ISSN (online)	1532-1940
ISSN	0266-4356
DOI	10.1016/j.bjoms.2023.07.003
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Uk I Zs.238: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Pregnenolone enhances the proliferation of mouse neural stem cells and promotes oligodendrogenesis, together with Sox10, and neurogenesis, along with Notch1 and Pax6.

Negintaji, Kourosh / Ghanbari, Amir / Frozanfar, Mohsen / Jafarinia, Mojtaba / Zibara, Kazem

Neurochemistry international

2023 Volume 163, Page(s) 105489

Abstract: Background: Pregnenolone is a precursor of various steroid hormones involved in osteoblast proliferation, microtubules polymerization and cell survival protection. Previous reports focused on the effects of pregnenolone metabolites on stem cell ... ...

Abstract	Background: Pregnenolone is a precursor of various steroid hormones involved in osteoblast proliferation, microtubules polymerization and cell survival protection. Previous reports focused on the effects of pregnenolone metabolites on stem cell proliferation and differentiation; however, the effects of pregnenolone itself has not been well explored. The present study aimed to investigate the role of pregnenolone on NSC proliferation and to determine the doses required for NSC differentiation as well as the various genes involved in its mechanism of action. Methods: NSCs were isolated from the embryonic cortex of E14 mice, incubated for 5 days, and then treated with pregnenolone doses of 2, 5, 10, 15 and 20 μM for another 5 days. The number of neurospheres and neurosphere derived cells were then counted. Flow cytometry was used to evaluate the differentiation of NSCs into oligodendrocytes, astrocytes, and neurons. The expression level of Notch1, Pax6 and Sox10 genes were also measured by Real Time PCR after 5 days of treatment. Results: Our data suggest that treatment with 10 μM pregnenolone is optimal for NSC proliferation. In fact, this concentration caused the highest increase in the number of neurospheres and neurosphere derived cells, compared to the control group. In addition, treatment with low doses of pregnenolone (5 and 10 μM) caused a significant increase in NSC differentiation towards immature (Olig2 Conclusion: Pregnenolone regulates NSCs proliferation in vitro. Treatment with low doses of pregnenolone caused an increase in the differentiation of NSCs into mature oligodendrocytes while higher doses increased the differentiation of NSCs into neurons. Oligodendrogenesis was accompanied by Sox10 while neurogenesis occurred together with Notch1 and Pax6 expression.
MeSH term(s)	Animals ; Mice ; Cell Differentiation/physiology ; Cell Proliferation ; Cells, Cultured ; Neural Stem Cells/metabolism ; Neurogenesis/physiology ; Neurons/metabolism ; PAX6 Transcription Factor/metabolism ; SOXE Transcription Factors/metabolism ; Tubulin/metabolism ; Pregnenolone/pharmacology ; Receptor, Notch1/metabolism
Chemical Substances	Pax6 protein, mouse ; PAX6 Transcription Factor ; Sox10 protein, mouse ; SOXE Transcription Factors ; Tubulin ; Pregnenolone (73R90F7MQ8) ; Notch1 protein, mouse ; Receptor, Notch1
Language	English
Publishing date	2023-01-16
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	283190-9
ISSN	1872-9754 ; 0197-0186
ISSN (online)	1872-9754
ISSN	0197-0186
DOI	10.1016/j.neuint.2023.105489
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1610: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Thymol-loaded liposomes effectively induced apoptosis and decreased EGFR expression in colorectal cancer cells.

Keshavarz, Fatemeh / Soltanshahi, Mohsen / Khosravani, Fatemeh / Bakhshiyan, Farzaneh / Ghanbari, Amir / Hassanzadeh, Sajad / Amirpour, Mozhgan / Ghalamfarsa, Ghasem

Naunyn-Schmiedeberg's archives of pharmacology

2024

Abstract: Background: Colorectal cancer (CRC) is one of the most common and deadly cancers worldwide. Different factors, such as environmental and genetic factors and lifestyle, affect it. Owing to the presence of phenolic, alkaloid, antioxidant, and terpenoid ... ...

Abstract	Background: Colorectal cancer (CRC) is one of the most common and deadly cancers worldwide. Different factors, such as environmental and genetic factors and lifestyle, affect it. Owing to the presence of phenolic, alkaloid, antioxidant, and terpenoid compounds, herbal compounds can be effective in the treatment of various cancers. Thymol is a natural monoterpene phenol that is abundant in some plants and exerts several biological effects. The aim of this study was to investigate the apoptotic, anti-proliferative effect and EGFR gene expression under the influence of thymol-loaded nanoliposome in SW84 and SW111 cell lines derived from colorectal cancer. Materials and methods: The lipid thin-film hydration method was used to synthesize thymol-loaded liposomes, and their characterization was performed using TEM, DLS, and HPLC analyses. SW84 and SW1111 cells were treated with thymol- and thymol-loaded liposomes at different doses, the inhibition of cell proliferation was evaluated using an MTT assay, the rate of apoptosis induction was assessed using flow cytometry, and EGFR gene expression was measured using real-time PCR. Results: The nanoparticles produced were spherical, uniform, and 200 ± 10 nm in size. HPLC analysis showed that approximately 98% thymol was loaded into the nanoliposome. The results of the MTT assay showed that thymol and thymol-nanoliposomes decreased the proliferation of SW84 and SW1111 cells in a concentration-dependent manner. The IC50 of thymol and thymol-nanoliposomes were 18 and 14.2 µg/ml for the SW48 cell line (P = 0.04) and 10.5 and 6.4 µg/ml for the SW1116 cell line (P = 0.001). Thymol-nanoliposomes significantly inhibited the proliferation of cancer cells compared to free thymol. Flow cytometry showed an increase in the percentage of apoptotic cells, especially in the thymol-nanoliposome group in the treated cells. Real-time PCR results also showed that thymol and thymol-nanoliposome both caused a decrease in the expression of EGFR genes in both cell lines, but this effect of decreasing gene expression was significantly higher in the thymol-nanoliposome group. Conclusions: Our results showed that thymol-nanoliposomes reduced proliferation, increased apoptosis, and decreased EGFR expression in colorectal cancer-derived cell lines.
Language	English
Publishing date	2024-01-19
Publishing country	Germany
Document type	Journal Article
ZDB-ID	121471-8
ISSN	1432-1912 ; 0028-1298
ISSN (online)	1432-1912
ISSN	0028-1298
DOI	10.1007/s00210-024-02945-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Ud II Zs.5: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Risk analysis of gas leakage in gas pressure reduction station and its consequences: A case study for Zahedan.

Dadkani, Peiman / Noorzai, Esmatullah / Ghanbari, AmirHossein / Gharib, Ali

Heliyon

2021 Volume 7, Issue 5, Page(s) e06911

Abstract: Industrial accidents have increased the importance of dealing with the risks of toxic exposure, fire and explosion. Despite the measures taken in the chemical industry to prevent accidents, the accidents occur often due to human error or process faults ... ...

Abstract	Industrial accidents have increased the importance of dealing with the risks of toxic exposure, fire and explosion. Despite the measures taken in the chemical industry to prevent accidents, the accidents occur often due to human error or process faults during repairs. Although several studies have been conducted on the accidents in the process industry, no research has modeled the risks caused by the leakage of toxic substances in the gas pressure reduction station. The consequences of gas leak and fire in Zahedan's gas pressure reduction station were investigated in Iran. This research aims to determine the safe range of the station and observe the safety measures required for the gas pressure reduction station in Zahedan. For modelling gas leak and fire, the ALOHA software was used to display the threat zone. In this research, with respect to the environmental data, the desired scenario was modeled. The results, based on two scenarios of gas leak and fire in both hot and cold seasons, indicate that the gas leak scenario in hot seasons and the fire scenario in cold seasons influence a larger region.
Language	English
Publishing date	2021-05-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2021.e06911
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Predictors of rural driver self-reported passing behaviors when interacting with farm equipment on the roadway.

Ghanbari, Amir / Hamann, Cara / Jansson, Stephanie / Reyes, Michelle / Faust, Kayla / Cavanaugh, Joseph / Askelson, Natoshia / Peek-Asa, Corinne

Transportation research interdisciplinary perspectives

2023 Volume 22, Issue 100926

Abstract: Background: Crashes involving farm equipment (FE) are a major safety concern for farmers as well as all other users of the public road system in both rural and urban areas. These crashes often involve passenger vehicle drivers striking the farm ... ...

Abstract	Background: Crashes involving farm equipment (FE) are a major safety concern for farmers as well as all other users of the public road system in both rural and urban areas. These crashes often involve passenger vehicle drivers striking the farm equipment from behind or attempting to pass, but little is known about drivers' perceived norms and self-reported passing behaviors. The objective of this study is to examine factors influencing drivers' farm equipment passing frequencies and their perceptions about the passing behaviors of other drivers. Methods: Data were collected via intercept surveys with adult drivers at local gas stations in two small rural towns in Iowa. The survey asked drivers about their demographic information, frequency of passing farm equipment, and perceptions of other drivers' passing behavior in their community and state when approaching farm equipment (proximal and distal descriptive norms). A multinomial logistic regression model was used to estimate the relationship between descriptive norms and self-reported passing behavior. Results: Survey data from 201 adult drivers showed that only 10% of respondents considered farm equipment crashes to be a top road safety concern. Respondents who perceived others passing farm equipment frequently in their community were more likely to report that they also frequently pass farm equipment. The results also showed interactions between gender and experience operating farm equipment in terms of self-reported passing behavior. Conclusions/implications: Results from this study suggest local and state-level norms and perceptions of those norms may be important targets for intervention to improve individual driving behaviors around farm equipment.
Language	English
Publishing date	2023-09-27
Publishing country	Netherlands
Document type	Journal Article
ISSN	2590-1982
ISSN (online)	2590-1982
DOI	10.1016/j.trip.2023.100926
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article: Association between neutrophil/lymphocyte ratio and disease severity in scleroderma patients.

Nejatifar, Fatemeh / Mirbolouk, Neda / Masooleh, Irandokht Shenavar / Kazemnejad, Ehsan / Ghavidel-Parsa, Banafsheh / Ghanbari, Amir Mohammad / Zayeni, Habib

Heliyon

2023 Volume 9, Issue 10, Page(s) e20576

Abstract: Introduction: Systemic sclerosis is a chronic and progressive connective tissue disease with various manifestation. Inflammatory status is developed in early stages and is followed by major organs' dysfunction. Disease severity is evaluated mostly ... ...

Abstract	Introduction: Systemic sclerosis is a chronic and progressive connective tissue disease with various manifestation. Inflammatory status is developed in early stages and is followed by major organs' dysfunction. Disease severity is evaluated mostly through Medsger scale. There is not any single laboratory test to evaluate disease severity, although some hematologic can reflect disease severity. In this study, we evaluated the association between hematologic indices (specially Neutrophil/Lymphocyte ratio) and Medsger score of disease severity. Materials and methods: One hundred and twenty-three patients along with the same number of healthy controls were enrolled in this study. Demographic information and past medical records were gathered in first appointment. Hematologic indices were calculated based on the laboratory findings and the association between these indices and Medsger score of disease severity was evaluated. Results: One hundred and twenty-three patients with mean disease duration of 9.54 and mean Medsger score of 7.42 were investigated in this study. Neutrophil count, erythrocyte sedimentation rate, red cell distribution width and NLR were significantly higher and mean platelets volume was significantly lower in SSc patients in comparison to controls. NLR was significantly correlated with pulmonary and cardiac involvements and Monocyte/Lymphocyte ratio was significantly correlated with the involvement of joint and tendons. We showed that NLR is a predictive factor for the severity of systemic sclerosis. We also found a cut off Value of 1.9 for NLR as a predictor for disease severity in our patients. Conclusion: Our study shows that SSc and its severity is associated with some hematologic indices like NLR, MLR, platelets and hemoglobin. These indices can also specifically predict the involvement of some organs.
Language	English
Publishing date	2023-09-30
Publishing country	England
Document type	Journal Article
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2023.e20576
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Safflower seed oil, a rich source of linoleic acid, stimulates hypothalamic neurogenesis

Barmak, Mehrzad Jafari / Nouri, Ebrahim / Shahraki, Maryam Hashemi / Ghalamfarsa, Ghasem / Zibara, Kazem / Delaviz, Hamdallah / Ghanbari, Amir

Anatomy & cell biology

2023 Volume 56, Issue 2, Page(s) 219–227

Abstract: Adult neurogenesis has been reported in the hypothalamus, subventricular zone and subgranular zone in the hippocamp. Recent studies indicated that new cells in the hypothalamus are affected by diet. We previously showed beneficial effects of safflower ... ...

Abstract	Adult neurogenesis has been reported in the hypothalamus, subventricular zone and subgranular zone in the hippocamp. Recent studies indicated that new cells in the hypothalamus are affected by diet. We previously showed beneficial effects of safflower seed oil (SSO), a rich source of linoleic acid (LA; 74%), on proliferation and differentiation of neural stem cells (NSCs)
Language	English
Publishing date	2023-03-27
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2590173-4
ISSN	2093-3673 ; 2093-3665
ISSN (online)	2093-3673
ISSN	2093-3665
DOI	10.5115/acb.22.220
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Risk analysis of gas leakage in gas pressure reduction station and its consequences: A case study for Zahedan

Dadkani, Peiman / Noorzai, Esmatullah / Ghanbari, AmirHossein / Gharib, Ali

Heliyon. 2021 May, v. 7, no. 5

2021

Abstract	Industrial accidents have increased the importance of dealing with the risks of toxic exposure, fire and explosion. Despite the measures taken in the chemical industry to prevent accidents, the accidents occur often due to human error or process faults during repairs. Although several studies have been conducted on the accidents in the process industry, no research has modeled the risks caused by the leakage of toxic substances in the gas pressure reduction station. The consequences of gas leak and fire in Zahedan's gas pressure reduction station were investigated in Iran. This research aims to determine the safe range of the station and observe the safety measures required for the gas pressure reduction station in Zahedan. For modelling gas leak and fire, the ALOHA software was used to display the threat zone. In this research, with respect to the environmental data, the desired scenario was modeled. The results, based on two scenarios of gas leak and fire in both hot and cold seasons, indicate that the gas leak scenario in hot seasons and the fire scenario in cold seasons influence a larger region.
Keywords	case studies ; chemical industry ; cold ; computer software ; risk analysis ; toxicity ; Iran
Language	English
Dates of publication	2021-05
Publishing place	Elsevier Ltd
Document type	Article
Note	NAL-AP-2-clean
ZDB-ID	2835763-2
ISSN	2405-8440
ISSN	2405-8440
DOI	10.1016/j.heliyon.2021.e06911
Database	NAL-Catalogue (AGRICOLA)

Order via subito

Article: Hormones in experimental autoimmune encephalomyelitis (EAE) animal models.

Ghareghani, Majid / Ghanbari, Amir / Eid, Ali / Shaito, Abdullah / Mohamed, Wael / Mondello, Stefania / Zibara, Kazem

Translational neuroscience

2021 Volume 12, Issue 1, Page(s) 164–189

Abstract: Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) in which activated immune cells attack the CNS and cause inflammation and demyelination. While the etiology of MS is still largely unknown, the ... ...

Abstract	Multiple sclerosis (MS) is an inflammatory demyelinating disease of the central nervous system (CNS) in which activated immune cells attack the CNS and cause inflammation and demyelination. While the etiology of MS is still largely unknown, the interaction between hormones and the immune system plays a role in disease progression, but the mechanisms by which this occurs are incompletely understood. Several
Language	English
Publishing date	2021-05-06
Publishing country	Germany
Document type	Journal Article ; Review
ZDB-ID	2581219-1
ISSN	2081-6936 ; 2081-3856
ISSN (online)	2081-6936
ISSN	2081-3856
DOI	10.1515/tnsci-2020-0169
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Evaluation of the Biodistribution of Arginine, glycine, aspartic acid peptide-modified Nanoliposomes Containing Curcumin in Rats.

Salehi Najafabadi, Parisa / Delaviz, Hamdollah / Asfaram, Arash / Jafari Barmak, Mehrzad / Ghanbari, Amir / Alipour, Mohsen / Rad, Parastou / Bardania, Hassan

Iranian journal of biotechnology

2022 Volume 20, Issue 2, Page(s) e2990

Abstract: Background: Liposomes, as a biological membrane, is successfully used for drug delivery, reduces toxicity in normal cells and improves bio-accessibility of the drug to the target cells. Curcumin, as a bioactive substance with pleiotropic biological ... ...

Abstract	Background: Liposomes, as a biological membrane, is successfully used for drug delivery, reduces toxicity in normal cells and improves bio-accessibility of the drug to the target cells. Curcumin, as a bioactive substance with pleiotropic biological activities, is an anti-inflammatory compound and has several anticancer effects in different cancers such as pancreatic and breast cancer. Objectives: This study was conducted to determine the bio-distribution of arginine-glycine-aspartic acid (RGD)-modified nanoliposomes containing curcumin in different tissues of rats. Materials and methods: The amount of curcumin in each tissue was examined by HPLC analysis. The distribution of liposomal Hoechst in the rats was evaluated by using fluorescence spectrophotometry, live animal imaging analyses and histological methods. Results: HPLC analysis showed the mean of curcumin in the blood significantly increased in the liposomal curcumin modified with RGD compared to free curcumin. These results were confirmed by fluorescence measurement for RGD modified liposome containing Hoechst dye. There was negligible fluorescent intensity in the blood rats, which received Hoechst alone. Live animal imaging analysis showed the presence of fluorescent color in heart tissue for all groups. It was also detected in kidney tissue for liposomal Hoechst modified with RGD group. Conclusions: The present study demonstrated that RGD-modified nano-liposomes can significantly improve drug retention time in the blood of rats.
Language	English
Publishing date	2022-04-01
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2223669-7
ISSN	2322-2921 ; 1728-3043
ISSN (online)	2322-2921
ISSN	1728-3043
DOI	10.30498/ijb.2021.272168.2990
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

Order via subito