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  1. Article ; Online: Is it possible to predict post-adenotonsillectomy hemorrhage in children with preoperative blood tests? Single-center retrospective study.

    Epure, Veronica / Gheorghe, Dan Cristian

    Science progress

    2023  Volume 106, Issue 4, Page(s) 368504231215591

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Humans ; Child ; Adenoidectomy ; Tonsillectomy/adverse effects ; Retrospective Studies ; Lymphocytosis ; Hemorrhage ; Hematologic Tests
    Language English
    Publishing date 2023-12-06
    Publishing country England
    Document type Observational Study ; Journal Article
    ZDB-ID 128412-5
    ISSN 2047-7163 ; 0036-8504 ; 0302-1785
    ISSN (online) 2047-7163
    ISSN 0036-8504 ; 0302-1785
    DOI 10.1177/00368504231215591
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 731: Show issues Location:
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  2. Article ; Online: Efficacy of Continuous Suctioning in Adenoidectomy Haemostasis-Clinical Study.

    Epure, Veronica / Hainarosie, Razvan / Gheorghe, Dan Cristian

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 9

    Abstract: ... ...

    Abstract Introduction
    MeSH term(s) Humans ; Child ; Adenoidectomy/adverse effects ; Blood Loss, Surgical/prevention & control ; Prospective Studies ; Postoperative Hemorrhage/etiology ; Hemostatics/therapeutic use ; Hemostasis
    Chemical Substances Hemostatics
    Language English
    Publishing date 2023-08-24
    Publishing country Switzerland
    Document type Randomized Controlled Trial ; Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59091534
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6270: Show issues Location:
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  3. Article: Good outcome of tracheostomy in a COVID-19 child with Joubert syndrome-Case report.

    Epure, Veronica / Oprea, Doru / Gheorghe, Dan Cristian

    Clinical case reports

    2023  Volume 11, Issue 2, Page(s) e6973

    Abstract: Pediatric tracheostomy in COVID-19 patients is a rarity. Joubert syndrome is a rare genetic disease, involving a lack of muscle control. We report the case of a child with Joubert syndrome and a severe form of COVID-19 infection, in whom we performed ... ...

    Abstract Pediatric tracheostomy in COVID-19 patients is a rarity. Joubert syndrome is a rare genetic disease, involving a lack of muscle control. We report the case of a child with Joubert syndrome and a severe form of COVID-19 infection, in whom we performed tracheostomy in order to replace prolonged intubation and mechanical ventilation; successful decannulation was performed after 12 months. Successful decannulation is still possible in a child with severe comorbidities (Joubert syndrome) even if it might take much longer than in patients without comorbidities.
    Language English
    Publishing date 2023-02-15
    Publishing country England
    Document type Case Reports
    ZDB-ID 2740234-4
    ISSN 2050-0904
    ISSN 2050-0904
    DOI 10.1002/ccr3.6973
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Use and Abuse of Electrocautery in Adenoidectomy Hemostasis.

    Epure, Veronica / Hainarosie, Razvan / Voiosu, Catalina / Gheorghe, Dan Cristian

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 4

    Abstract: Background and objectives: ...

    Abstract Background and objectives:
    MeSH term(s) Child ; Humans ; Adenoidectomy/adverse effects ; Adenoidectomy/methods ; Halitosis/etiology ; Nasal Obstruction/complications ; Velopharyngeal Insufficiency/complications ; Neck Pain/complications ; Pain, Postoperative/etiology ; Pain, Postoperative/epidemiology ; Electrocoagulation/adverse effects ; Electrocoagulation/methods ; Hemostasis
    Language English
    Publishing date 2023-04-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59040739
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Cardiovascular Effects of Cumulative Doses of Radioiodine in Differentiated Thyroid Cancer Patients with Type 2 Diabetes Mellitus.

    Stanciu, Adina Elena / Stanciu, Marcel Marian / Zamfirescu, Anca / Gheorghe, Dan Cristian

    Cancers

    2022  Volume 14, Issue 10

    Abstract: Radioiodine (131I) therapy for differentiated thyroid cancer (DTC) involves exposure of the whole body, including the heart, to ionizing radiation. This exposure to the subsequent risk of heart disease is uncertain, especially in patients with DTC ... ...

    Abstract Radioiodine (131I) therapy for differentiated thyroid cancer (DTC) involves exposure of the whole body, including the heart, to ionizing radiation. This exposure to the subsequent risk of heart disease is uncertain, especially in patients with DTC associated with type 2 diabetes mellitus (DTC/+T2DM). The current study aimed to assess the relationship between left ventricular ejection fraction (LVEF), high cumulative 131I dose, and peripheral blood parameters in patients with DTC/−T2DM and DTC/+T2DM. The study enrolled 72 female patients with DTC/−T2DM and 24 with DTC/+T2DM who received cumulative 131I doses above 150 mCi (5.55 GBq). LVEF was lower in patients with concomitant T2DM than those without (p < 0.001). The cumulative 131I dosage was inversely correlated with LVEF only in DTC/−T2DM patients (r = −0.57, p < 0.001). In the DTC/+T2DM group, LVEF was negatively associated with absolute platelet count (r = −0.67, p < 0.001) and platelet-to-lymphocyte ratio (r = −0.76, p < 0.001). Our results demonstrate that exposure to high cumulative 131I doses has different cardiovascular effects in DTC/−T2DM and DTC/+T2DM.
    Language English
    Publishing date 2022-05-10
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2527080-1
    ISSN 2072-6694
    ISSN 2072-6694
    DOI 10.3390/cancers14102359
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Persistent Stapedial Artery, Oval Window Atresia and Congenital Stapes Agenesis-Case Report.

    Gheorghe, Dan Cristian / Epure, Veronica / Oprea, Doru / Zamfir-Chiru-Anton, Adina

    Medicina (Kaunas, Lithuania)

    2023  Volume 59, Issue 3

    Abstract: ... ...

    Abstract Background
    MeSH term(s) Male ; Child ; Humans ; Stapes/abnormalities ; Stapes/blood supply ; Ossicular Prosthesis ; Hearing Loss, Conductive/etiology ; Hearing Loss, Conductive/surgery ; Ear, Middle/abnormalities ; Ear, Middle/surgery ; Arteries/abnormalities
    Language English
    Publishing date 2023-02-25
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina59030461
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  7. Article ; Online: Eustachian Tube Teratoma: A Rare Entity.

    Gheorghe, Dan Cristian / Enculescu, Augustina / Stanciu, Adina Elena / Epure, Veronica / Zamfir-Chiru-Anton, Adina

    Clinical pathology (Thousand Oaks, Ventura County, Calif.)

    2023  Volume 16, Page(s) 2632010X231195231

    Abstract: Introduction: Teratomas, tumors derived from all 3 fetal germ cell layers, are rarely located in the head and neck region and extremely rare in the Eustachian tube area.: Case report: The authors present the case of a 2 years old child with chronic ... ...

    Abstract Introduction: Teratomas, tumors derived from all 3 fetal germ cell layers, are rarely located in the head and neck region and extremely rare in the Eustachian tube area.
    Case report: The authors present the case of a 2 years old child with chronic ear discharge. Referral diagnosis was tumor or cyst of the temporal bone. Intraoperatively, a solid, hairy tumor located inside the Eustachain tube, with extension into the middle ear space was discovered and removed. Histology revealed a mature teratoma. Review of the literature showed reports of rare similar cases of Eustachian tube teratomas, differentiating themfrom hairy polyps of the rhynopharynx. The imaging of our patient, the surgical techique for removal of the tumor and long term follow-up are detailed.
    Conclusions: Teratomas located inside the Eustachian tube are exceptional. Their removal should be carefully planned in view of their long term anatomical sequelae and in order to avoid long term postoperative morbidity.
    Language English
    Publishing date 2023-08-17
    Publishing country United States
    Document type Case Reports
    ISSN 2632-010X
    ISSN (online) 2632-010X
    DOI 10.1177/2632010X231195231
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: MMP-2 and MMP-9 gene polymorphisms and risk of head and neck carcinomas

    Schipor Sorina / Zamfir Adina / Gheorghe Dan Cristian / Picu Catalina / Manda Dana

    Romanian Journal of Laboratory Medicine, Vol 30, Iss 2, Pp 163-

    2022  Volume 171

    Abstract: Background: Head and neck carcinomas (HNC) account for a majority of ear, nose and throat tumours. They account for 6.3% of all incident malignancies and 6.2 % of all deaths from cancer in Romania in 2020, the fifth most common cancer in this Eastern ... ...

    Abstract Background: Head and neck carcinomas (HNC) account for a majority of ear, nose and throat tumours. They account for 6.3% of all incident malignancies and 6.2 % of all deaths from cancer in Romania in 2020, the fifth most common cancer in this Eastern Europe country. Aim of the study: The aim of our study was to investigate the association between two MMP-2 and MMP-9 promoter gene polymorphisms and head and neck cancer.
    Keywords risk ; polymorphism ; mmp-9 ; mmp-2 ; head and neck squamous cell carcinomas ; Medicine ; R
    Language English
    Publishing date 2022-04-01T00:00:00Z
    Publisher Sciendo
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  9. Article: Biomaterials for the Prevention of Oral Candidiasis Development.

    Gheorghe, Dan Cristian / Niculescu, Adelina-Gabriela / Bîrcă, Alexandra Cătălina / Grumezescu, Alexandru Mihai

    Pharmaceutics

    2021  Volume 13, Issue 6

    Abstract: Thousands of microorganisms coexist within the human microbiota. However, certain conditions can predispose the organism to the overgrowth of specific pathogens that further lead to opportunistic infections. One of the most common such imbalances in the ... ...

    Abstract Thousands of microorganisms coexist within the human microbiota. However, certain conditions can predispose the organism to the overgrowth of specific pathogens that further lead to opportunistic infections. One of the most common such imbalances in the normal oral flora is the excessive growth of
    Language English
    Publishing date 2021-05-27
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2527217-2
    ISSN 1999-4923
    ISSN 1999-4923
    DOI 10.3390/pharmaceutics13060803
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  10. Article: Nanoparticles for the Treatment of Inner Ear Infections.

    Gheorghe, Dan Cristian / Niculescu, Adelina-Gabriela / Bîrcă, Alexandra Cătălina / Grumezescu, Alexandru Mihai

    Nanomaterials (Basel, Switzerland)

    2021  Volume 11, Issue 5

    Abstract: The inner ear is sensitive to various infections of viral, bacterial, or fungal origin, which, if left untreated, may lead to hearing loss or progress through the temporal bone and cause intracranial infectious complications. Due to its isolated location, ...

    Abstract The inner ear is sensitive to various infections of viral, bacterial, or fungal origin, which, if left untreated, may lead to hearing loss or progress through the temporal bone and cause intracranial infectious complications. Due to its isolated location, the inner ear is difficult to treat, imposing an acute need for improving current therapeutic approaches. A solution for enhancing antimicrobial treatment performance is the use of nanoparticles. Different inorganic, lipidic, and polymeric-based such particles have been designed, tested, and proven successful in the controlled delivery of medication, improving drug internalization by the targeted cells while reducing the systemic side effects. This paper makes a general presentation of common inner ear infections and therapeutics administration routes, further focusing on newly developed nanoparticle-mediated treatments.
    Language English
    Publishing date 2021-05-17
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano11051311
    Database MEDical Literature Analysis and Retrieval System OnLINE

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