Article ; Online: Histopathological findings in the advanced natural evolution of the SARS-CoV-2 infection.
Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
2020 Volume 61, Issue 1, Page(s) 209–218
Abstract: We are reporting a case of natural evolution and pathological data from a young person that was diagnosed with coronavirus disease 2019 (COVID-19). All data has been collected from the autopsy of a 30-year-old female, which was performed by the ... ...
| Abstract | We are reporting a case of natural evolution and pathological data from a young person that was diagnosed with coronavirus disease 2019 (COVID-19). All data has been collected from the autopsy of a 30-year-old female, which was performed by the Department of Forensic Medicine from Emergency County Hospital, Drobeta Turnu Severin, Mehedinţi County, Romania. The infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was confirmed by reverse transcription polymerase chain reaction (RT-PCR) on the lung tissue which was obtained during autopsy. This case provides the opportunity to study the natural evolution of COVID-19 pneumonia in a young person with clinical signs of pneumonia but without associated comorbidities. The patient had not received any treatment. The histopathological examination of the lung revealed a process of productive proliferation, proteinaceous and fibrin-macrophagic interalveolar spaces exudate, and lesions consistent with vasculitis. In the heart, we identified a cardiac thrombus. These changes are likely to suggest an advanced natural evolution of SARS-CoV-2 virus infection. |
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| MeSH term(s) | Adult ; Autopsy ; Betacoronavirus ; COVID-19 ; COVID-19 Testing ; Clinical Laboratory Techniques ; Coronavirus Infections/diagnosis ; Coronavirus Infections/physiopathology ; Coronavirus Infections/virology ; Female ; Humans ; Kidney/pathology ; Liver/pathology ; Lung/pathology ; Lung/virology ; Myocardium/pathology ; Pancreas/pathology ; Pandemics ; Pneumonia, Viral/physiopathology ; Pneumonia, Viral/virology ; Reverse Transcriptase Polymerase Chain Reaction ; Romania ; SARS-CoV-2 ; Thrombosis/pathology ; Thrombosis/virology |
| Keywords | covid19 |
| Language | English |
| Publishing date | 2020-10-19 |
| Publishing country | Romania |
| Document type | Case Reports ; Journal Article |
| ZDB-ID | 1062519-7 |
| ISSN | 2066-8279 ; 1220-0522 ; 0035-4007 |
| ISSN (online) | 2066-8279 |
| ISSN | 1220-0522 ; 0035-4007 |
| DOI | 10.47162/RJME.61.1.23 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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