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  1. Article: Oral Health of Patients Undergoing Percutaneous Coronary Intervention-A Possible Link between Periodontal Disease and In-Stent Restenosis.

    Nagy, Ferenc Tamás / Gheorghita, Dorottya / Dharmarajan, Lalli / Braunitzer, Gábor / Achim, Alexandru / Ruzsa, Zoltán / Antal, Márk Ádám

    Journal of personalized medicine

    2023  Volume 13, Issue 5

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2023-04-28
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662248-8
    ISSN 2075-4426
    ISSN 2075-4426
    DOI 10.3390/jpm13050760
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: A fogágybetegség mint az atheroscleroticus cardiovascularis betegség rizikófaktora.

    Gheorghita, Dorottya / Eördegh, Gabriella / Nagy, Ferenc / Antal, Márk

    Orvosi hetilap

    2019  Volume 160, Issue 11, Page(s) 419–425

    Abstract: Cardiovascular disease is recognized as the leading cause of death and disability in the world. The majority of these deaths can be attributed to atherosclerotic disease and thromboembolic events leading to ischemic heart disease and stroke. The role of ... ...

    Title translation Periodontal disease, a risk factor for atherosclerotic cardiovascular disease.
    Abstract Cardiovascular disease is recognized as the leading cause of death and disability in the world. The majority of these deaths can be attributed to atherosclerotic disease and thromboembolic events leading to ischemic heart disease and stroke. The role of inflammation is well recognized in the pathogenesis of atherosclerosis and atherothrombosis. Increasing number of studies support the hypothesis that periodontal disease, specifically periodontitis, is a potential risk factor for atherosclerosis and thus cardiovascular disease. Chronic infections of periodontal pockets act as reservoirs for pathogenic microorganisms, their toxins and degradation products, raising the overall systemic inflammatory burden. Entering the circulation and atherosclerotic lesions themselves, they lead to further local and systemic inflammatory response, in all contributing to atherosclerosis progression, potentially increasing cardiovascular risk. Along these lines, good oral health in general and the periodontal treatment in more severe cases may play a role in cardiovascular risk reduction, primary and secondary prevention. The present review summarizes the possible pathophysiological mechanisms linking periodontal and cardiovascular pathology, lists clinical evidence between periodontitis and specific forms of cardiovascular disease and looks forward at the potential role of periodontal treatment in cardiovascular disease prevention and treatment. Orv Hetil. 2019; 160(11): 419-425.
    MeSH term(s) Atherosclerosis ; Cardiovascular Diseases ; Humans ; Periodontal Diseases ; Periodontitis ; Risk Factors
    Language Hungarian
    Publishing date 2019-03-21
    Publishing country Hungary
    Document type Journal Article ; Review
    ZDB-ID 123879-6
    ISSN 1788-6120 ; 0030-6002
    ISSN (online) 1788-6120
    ISSN 0030-6002
    DOI 10.1556/650.2019.31301
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 301: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  3. Article ; Online: Aerosol Reduction of 2 Dental Extraoral Scavenger Devices In Vitro.

    Gheorghita, Dorottya / Kun Szabó, Fruzsina / Ajtai, Tibor / Hodovány, Szabolcs / Bozóki, Zoltán / Braunitzer, Gábor / Antal, Márk Ádám

    International dental journal

    2022  Volume 72, Issue 5, Page(s) 691–697

    Abstract: Objective: Since the outbreak of SARS-CoV-2, aerosol control in the operatory has become a key safety issue in dentistry. The utilisation of extraoral scavenger devices (EOSs) is one of the various approaches to in-treatment aerosol reduction in ... ...

    Abstract Objective: Since the outbreak of SARS-CoV-2, aerosol control in the operatory has become a key safety issue in dentistry. The utilisation of extraoral scavenger devices (EOSs) is one of the various approaches to in-treatment aerosol reduction in dentistry. The use and efficacy of EOSs in dental settings, however, are still a matter of debate in the literature and there are still open questions about their proper use. Thus, research into this area is essential to inform dental practice. The objective of this study was to examine the aerosol reduction efficacy of two different EOS in vitro.
    Methods: Two commercially available EOSs were tested during modeled dental treatment in a setup that previously proved to generate high aerosol load. Measurements were done in two particle size ranges: 5.6-560 nm (the full range of the spectrometer) and 60.4-392.4 nm (a range that is especially relevant to the spread of SARS-CoV-2 with aerosol).
    Results: Both devices managed to reduce the aerosol load to a statistically significant extent as compared to the scenario when only a high-volume evacuator and a saliva ejector (and no EOS) were used.
    Conclusions: Within the limitations of the study, the results support the assumption that EOSs for aerosol reduction increase in-treatment safety in the dental operatory.
    MeSH term(s) COVID-19/prevention & control ; Humans ; Respiratory Aerosols and Droplets ; SARS-CoV-2
    Language English
    Publishing date 2022-06-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 218262-2
    ISSN 1875-595X ; 0020-6539
    ISSN (online) 1875-595X
    ISSN 0020-6539
    DOI 10.1016/j.identj.2022.05.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 205: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Aerosol generation and control in the dental operatory: An in vitro spectrometric study of typical clinical setups.

    Kun-Szabó, Fruzsina / Gheorghita, Dorottya / Ajtai, Tibor / Hodovány, Szabolcs / Bozóki, Zoltán / Braunitzer, Gábor / Antal, Márk Ádám

    PloS one

    2021  Volume 16, Issue 2, Page(s) e0246543

    Abstract: Dental turbines and scalers, used every day in dental operatories, feature built-in water spray that generates considerable amounts of water aerosol. The problem is that it is not exactly known how much. Since the outbreak of COVID-19, several aerosol ... ...

    Abstract Dental turbines and scalers, used every day in dental operatories, feature built-in water spray that generates considerable amounts of water aerosol. The problem is that it is not exactly known how much. Since the outbreak of COVID-19, several aerosol safety recommendations have been issued-based on little empirical evidence, as almost no data are available on the exact aerosol concentrations generated during dental treatment. Similarly, little is known about the differences in the efficacy of different commercially available aerosol control systems to reduce in-treatment aerosol load. In this in vitro study, we used spectrometry to explore these questions. The time-dependent effect of conventional airing on aerosol concentrations was also studied. Everyday patient treatment situations were modeled. The test setups were defined by the applied instrument and its spray direction (high-speed turbine with direct/indirect airspray or ultrasonic scaler with indirect airspray) and the applied aerosol control system (the conventional high-volume evacuator or a lately introduced aerosol exhaustor). Two parameters were analyzed: total number concentration in the entire measurement range of the spectrometer and total number concentration within the 60 to 384 nm range. The results suggest that instrument type and spray direction significantly influence the resulting aerosol concentrations. Aerosol generation by the ultrasonic scaler is easily controlled. As for the high-speed turbine, the efficiency of control might depend on how exactly the instrument is used during a treatment. The results suggest that scenarios where the airspray is frequently directed toward the air of the operatory are the most difficult to control. The tested control systems did not differ in their efficiency, but the study could not provide conclusive results in this respect. With conventional airing through windows with a standard fan, a safety airing period of at least 15 minutes between treatments is recommended.
    MeSH term(s) Aerosols/administration & dosage ; Aerosols/adverse effects ; Aerosols/analysis ; COVID-19/etiology ; Dental Instruments/virology ; Dentistry/methods ; Equipment Design ; Humans ; Particle Size ; SARS-CoV-2/isolation & purification
    Chemical Substances Aerosols
    Language English
    Publishing date 2021-02-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0246543
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Periodontal Disease in Diabetes Mellitus: A Case-Control Study in Smokers and Non-Smokers.

    Battancs, Emese / Gheorghita, Dorottya / Nyiraty, Szabolcs / Lengyel, Csaba / Eördegh, Gabriella / Baráth, Zoltán / Várkonyi, Tamás / Antal, Márk

    Diabetes therapy : research, treatment and education of diabetes and related disorders

    2020  Volume 11, Issue 11, Page(s) 2715–2728

    Abstract: Introduction: It is well established that periodontal disease (PD) and diabetes mellitus (DM) can have a detrimental effect on each other's disease course, and that cigarette smoking exacerbates both conditions. However, literature on the periodontal ... ...

    Abstract Introduction: It is well established that periodontal disease (PD) and diabetes mellitus (DM) can have a detrimental effect on each other's disease course, and that cigarette smoking exacerbates both conditions. However, literature on the periodontal status of smokers with DM is scarce, and the studies conducted to date did not use healthy controls or non-smokers with DM as controls. Consequently, the individual effects of smoking and DM on PD are difficult to untangle and estimate.
    Methods: A total of 128 participants were recruited to this study and their data analyzed. They were assigned to four groups: smoking patients with DM (SDM); non-smoking patients with DM (NSDM); smokers without DM (control group, SC) and (4) non-smokers without DM (control group, NSC). Each group consisted of 32 age-matched participants. The periodontal status of the participants was assessed by full oral examination. To express periodontal status, we used the four-stage classification introduced by Fernandes and colleagues (J Periodontol. 80(7):1062-1068, 2009). The control of DM was estimated by measuring hemoglobin A1c (HbA1c) levels in the peripheral blood.
    Results: A significant difference in the severity of PD was found between the SC and NSC groups (p = 0.027) and between the NSC and SDM groups (p = 0.000), while the difference between the NSDM and SDM groups approached significance (p = 0.052). No person in the smoker groups could be classified as having a healthy periodontal status. The four-stage classification followed a normal distribution in the healthy, non-smoking controls (NSC). Smoking caused a shift toward medium-severe PD, while a marked shift toward the most severe stage was observed when both smoking and DM were present (SDM). There was no significant association between the type of DM and periodontal status, nor between diabetes control and the severity of PD. Persons in the SDM group had significantly fewer teeth than those in the NSC group (mean ± standard deviation: 16.0 ± 7.9 vs. 20.7 ± 5.6; p = 0.02).
    Conclusion: Smoking damages the periodontium of even healthy individuals, but the damage is multiplied in a smoker who has DM, even though the effect of DM alone on periodontium health is relatively mild. Our results suggest a synergy between DM and smoking in terms of damage to the periodontal tissues, but the limited sample size of this study does not allow any hard conclusion to be drawn.
    Language English
    Publishing date 2020-09-25
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2566702-6
    ISSN 1869-6961 ; 1869-6953
    ISSN (online) 1869-6961
    ISSN 1869-6953
    DOI 10.1007/s13300-020-00933-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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