LIVIVO - Search results -

Search results

Result 1 - 10 of total 51

Search options

Article ; Online: Efficacy of Oral Mucoadhesive N-Acetylcysteine Tablets in Treatment of Recurrent Aphthous Stomatitis: A Randomized Double-Blind, Placebo-Controlled Clinical Trial.

Eslami, Gohar / Ghorbani, Anahita / Akbari, Jafar / Farmoudeh, Ali / Faghih, Fereshteh / Moghimi, Minoo

Frontiers in dentistry

2023 Volume 20, Page(s) 18

Abstract: Objectives: ...

Abstract	Objectives:
Language	English
Publishing date	2023-05-31
Publishing country	Iran
Document type	Journal Article
ISSN	2676-296X
ISSN (online)	2676-296X
DOI	10.18502/fid.v20i18.12824
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Modified Score of Toxic Epidermal Necrolysis to predict toxic epidermal necrolysis mortality.

Haghani Dogahe, Zahra / Ghorbani, Anahita / Hallaj, Shahin / Mobayen, Mohammadreza

Journal of the American Academy of Dermatology

2022 Volume 88, Issue 1, Page(s) 254–255

MeSH term(s)	Humans ; Stevens-Johnson Syndrome/diagnosis ; Hospital Mortality ; Retrospective Studies ; Severity of Illness Index
Language	English
Publishing date	2022-05-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	603641-7
ISSN	1097-6787 ; 0190-9622
ISSN (online)	1097-6787
ISSN	0190-9622
DOI	10.1016/j.jaad.2022.05.020
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1540: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Reply: Galectin-3: A Pathophysiological Background Index or an Emerging Prognostic Biomarker in Heart Failure?

Ghorbani, Anahita / Ho, Jennifer E

Journal of the American College of Cardiology

2019 Volume 73, Issue 14, Page(s) 1875–1876

MeSH term(s)	Biomarkers ; Cardiovascular System ; Galectin 3 ; Heart Failure ; Humans ; Prognosis
Chemical Substances	Biomarkers ; Galectin 3
Language	English
Publishing date	2019-04-11
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	605507-2
ISSN	1558-3597 ; 0735-1097
ISSN (online)	1558-3597
ISSN	0735-1097
DOI	10.1016/j.jacc.2019.02.016
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1846: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
Zs.MO 196: Show issues

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Endoscopic, laboratory, and clinical findings and outcomes of caustic ingestion in adults; a retrospective study.

Banagozar Mohammadi, Ali / Zaare Nahandi, Maryam / Ostadi, Ali / Ghorbani, Anahita / Hallaj, Shahin

Gastroenterology and hepatology from bed to bench

2022 Volume 15, Issue 1, Page(s) 59–65

Abstract: Aim: Compared to the prevalence and complications, there is still limited evidence in this regard.: Background: With an incidence rate of 200,000 cases annually and the induction of numerous complications, caustic ingestion imposes a significant ... ...

Abstract	Aim: Compared to the prevalence and complications, there is still limited evidence in this regard. Background: With an incidence rate of 200,000 cases annually and the induction of numerous complications, caustic ingestion imposes a significant burden on the healthcare system. Apart from being fatal in some cases, this injury affects its victims' quality of life as it is followed by many gastrointestinal problems. This injury mainly occurs accidentally among children, whereas in adults, it often occurs with suicidal intentions. Despite recent advances in internal medicine, gastroenterology, and toxicology, this type of injury remains a debilitating and, in some cases, fatal disorder for its victims. Methods: This study retrospectively evaluated the clinical, laboratory, and endoscopic findings of 150 patients admitted to a referral center of toxicology and forensic medicine and assessed factors associated with each type of injury. Results: The findings indicated a mortality rate as high as 7.3% in this population. Age, pH, and previous medical conditions were associated with more complications. Higher degrees of injury were also significantly associated with higher mortality. No significant difference was observed between types of corrosive substances. Conclusion: It seems that the most effective intervention for controlling caustic ingestion injuries would be psychiatric support, primary healthcare, and household education.
Language	English
Publishing date	2022-05-18
Publishing country	Iran
Document type	Journal Article
ZDB-ID	2569124-7
ISSN	2008-4234 ; 2008-2258
ISSN (online)	2008-4234
ISSN	2008-2258
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Amelanotisk malignt melanom på en finger.

Ghorbani, Anahita / Jungersted, Jakob Mutanu

Ugeskrift for laeger

2017 Volume 179, Issue 16

Title translation	Amelanotic malignant melanoma on a finger.
MeSH term(s)	Aged ; Humans ; Male ; Melanoma, Amelanotic/pathology ; Melanoma, Amelanotic/surgery ; Nails/pathology ; Nails/surgery
Language	Danish
Publishing date	2017-04-17
Publishing country	Denmark
Document type	Case Reports
ZDB-ID	124102-3
ISSN	1603-6824 ; 0041-5782
ISSN (online)	1603-6824
ISSN	0041-5782
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.B 302: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)
Ua VI Zs.6/30: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Evaluation of zinc sulfate mucoadhesive formulation on recurrent aphthous stomatitis: a randomized double-blind, placebo-controlled clinical trial.

Ghorbani, Anahita / Akbari, Jafar / Boorboor, Maryam / Nekoukar, Zahra / Eslami, Gohar

BMC oral health

2020 Volume 20, Issue 1, Page(s) 212

Abstract: Background: Recurrent aphthous stomatitis (RAS) is a common lesion that affects the oral mucosa. There are several methods to treat RAS, including systemic and topical formulations. This study was conducted to evaluate the anti-inflammatory effect of ... ...

Abstract	Background: Recurrent aphthous stomatitis (RAS) is a common lesion that affects the oral mucosa. There are several methods to treat RAS, including systemic and topical formulations. This study was conducted to evaluate the anti-inflammatory effect of topical zinc sulfate and its efficacy in the treatment of RAS. Methods: A double-blind randomized clinical trial was conducted on 46 patients with RAS. They were randomly assigned into two groups to receive a zinc sulfate mucoadhesive tablet or placebo for 7 days. The pain severity was measured at baseline and daily while the diameter of the lesion was measured at baseline and on days 3, 5, and 7. The obtained data were analyzed in SPSS V.16. Results: There was no significant difference in the mean diameter of lesions and pain at baseline between the two groups (P = 0.643 and P = 0.842, respectively). However, on the third, fifth, and seventh days of the study, the diameter of the lesion significantly reduced in the intervention group (P = 0.001) and the pain intensity became significantly different between groups from the fourth day of the study (P = 0.001). Conclusion: Zinc sulfate mucoadhesive tablet was effective in recovery and reducing the pain and diameter of the aphthous lesion and could be considered for the treatment of RAS. Trial registration: Evaluation of the effectiveness of zinc sulfate mucoadhesive tablet in the improvement of recurrent aphthous stomatitis (RAS), IRCT20151109024975N9. Registered August 1, 2018, https://en.irct.ir/trial/32423 . This project was registered by the Iranian Registry of Clinical Trials ( http://www.irct.ir ). The IRCT ID was IRCT20151109024975N9.
MeSH term(s)	Double-Blind Method ; Humans ; Iran ; Stomatitis, Aphthous/drug therapy ; Treatment Outcome ; Zinc Sulfate/therapeutic use
Chemical Substances	Zinc Sulfate (7733-02-0)
Language	English
Publishing date	2020-07-28
Publishing country	England
Document type	Journal Article ; Randomized Controlled Trial ; Research Support, Non-U.S. Gov't
ZDB-ID	2091511-1
ISSN	1472-6831 ; 1472-6831
ISSN (online)	1472-6831
ISSN	1472-6831
DOI	10.1186/s12903-020-01194-4
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Adenosine: The common target between cancer immunotherapy and glaucoma in the eye

Hallaj, Shahin / Mirza-Aghazadeh-Attari, Mohammad / Arasteh, Amin / Ghorbani, Anahita / Lee, Daniel / Jadidi-Niaragh, Farhad

Life sciences. 2021 Oct. 01, v. 282

2021

Abstract: Adenosine, an endogenous purine nucleoside, is a well-known actor of the immune system and the inflammatory response both in physiologic and pathologic conditions. By acting upon particular, G-protein coupled adenosine receptors, i.e., A1, A2- a & b, and ...

Abstract	Adenosine, an endogenous purine nucleoside, is a well-known actor of the immune system and the inflammatory response both in physiologic and pathologic conditions. By acting upon particular, G-protein coupled adenosine receptors, i.e., A1, A2- a & b, and A3 receptors mediate a variety of intracellular and immunomodulatory actions. Several studies have elucidated Adenosine's effect and its up-and downstream molecules and enzymes on the anti-tumor response against several types of cancers. We have also targeted a couple of molecules to manipulate this pathway and get the immune system's desired response in our previous experiences. Besides, the outgrowth of the studies on ocular Adenosine in recent years has significantly enhanced the knowledge about Adenosine and its role in ocular immunology and the inflammatory response of the eye. Glaucoma is the second leading cause of blindness globally, and the recent application of Adenosine and its derivatives has shown the critical role of the adenosine pathway in its pathophysiology. However, despite a very promising background, the phase III clinical trial of Trabodenoson failed to achieve the non-inferiority goals of the study. In this review, we discuss different aspects of the abovementioned pathway in ophthalmology and ocular immunology; following a brief evaluation of the current immunotherapeutic strategies, we try to elucidate the links between cancer immunotherapy and glaucoma in order to introduce novel therapeutic targets for glaucoma.
Keywords	G-proteins ; adenosine ; blindness ; clinical trials ; eyes ; glaucoma ; immune system ; immunotherapy ; inflammation ; ophthalmology ; pathophysiology
Language	English
Dates of publication	2021-1001
Publishing place	Elsevier Inc.
Document type	Article
ZDB-ID	3378-9
ISSN	1879-0631 ; 0024-3205
ISSN (online)	1879-0631
ISSN	0024-3205
DOI	10.1016/j.lfs.2021.119796
Database	NAL-Catalogue (AGRICOLA)

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Bonn / Germany

Z 73/732: Show issues

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Anti-inflammatory and tissue repair effect of cinnamaldehyde and nano cinnamaldehyde on gingival fibroblasts and macrophages.

Ghardashpour, Mostafa / Saeedi, Majid / Negarandeh, Reza / Enderami, Seyed Ehsan / Ghorbani, Anahita / Lotfizadeh, Anahita / Jafari, Ali / Arezoumandi, Alireza / Hassannia, Hadi / Molania, Tahereh

BMC oral health

2023 Volume 23, Issue 1, Page(s) 1014

Abstract: Background: Recurrent aphthous stomatitis has a complex and inflammatory origin. Among the great variety of medications it is increasingly common to use herbal medicines due to the adverse side effects of chemical medications. Considering the anti- ... ...

Abstract	Background: Recurrent aphthous stomatitis has a complex and inflammatory origin. Among the great variety of medications it is increasingly common to use herbal medicines due to the adverse side effects of chemical medications. Considering the anti-inflammatory properties of cinnamaldehyde and the lack of studies related to the effectiveness of its nano form; This study investigates the effect of cinnamaldehyde and nano cinnamaldehyde on the healing rate of recurrent aphthous stomatitis lesions. Methods: In a laboratory experiment, cinnamaldehyde was converted into niosomal nanoparticles. The niosome vesicles diameter and polydispersity index were measured at 25°C using a dynamic light scattering (DLS) Mastersizer 2000 (Malvern Panalytical technologies: UK) and Zetasizer Nano ZS system (Malvern Instruments Worcestershire: UK). After characterizing these particles, the (2,3-Bis-(2-Methoxy-4-Nitro-5-Sulfophenyl)-2H-Tetrazolium-5-Carboxanilide) [XTT] assay was used to assess the toxicity of cinnamaldehyde and nano cinnamaldehyde on gingival fibroblast (HGF) and macrophage (THP-1) cells. By determining the release of TNF-α, IL-6, and TGF-β cytokines using ELISA kits, the level of tissue repair and anti-inflammatory capabilities of these two substances were evaluated. Results: The size and loading rate of the cinnamaldehyde nanoparticles were established after its creation. The optimized nanovesicle exhibited the following characteristics: particle size of 228.75 ± 2.38 nm, PDI of 0.244 ± 0.01, the zeta potential of -10.87 ± 1.09 mV and the drug encapsulation percentage of 66.72 ± 3.93%. PDIs range was between 0.242-0.274. The zeta potential values at 25°C were from -2.67 to -12.9 mV. The results of the XTT test demonstrated that nano cinnamaldehyde exhibited dose-dependent toxicity effects. Moreover, nano cinnamaldehyde released more TGF-β and had better reparative effects when taken at lower concentrations than cinnamaldehyde. Conclusion: Nano cinnamaldehyde and cinnamaldehyde are effective in repairing tissue when used in non-toxic amounts. After confirmation in animal models, it is envisaged that these substances can be utilized to treat recurrent aphthous stomatitis.
MeSH term(s)	Animals ; Stomatitis, Aphthous ; Macrophages ; Anti-Inflammatory Agents/pharmacology ; Fibroblasts ; Transforming Growth Factor beta/pharmacology
Chemical Substances	cinnamaldehyde (SR60A3XG0F) ; Anti-Inflammatory Agents ; Transforming Growth Factor beta
Language	English
Publishing date	2023-12-19
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2091511-1
ISSN	1472-6831 ; 1472-6831
ISSN (online)	1472-6831
ISSN	1472-6831
DOI	10.1186/s12903-023-03682-9
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Brain-derived extracellular vesicles as serologic markers of brain injury following cardiac arrest: A pilot feasibility study.

Shen, Hanfei / Zaitseva, Daria / Yang, Zijian / Forsythe, Liam / Joergensen, Sarah / Zone, Alea I / Shehu, Joana / Maghraoui, Sarah / Ghorbani, Anahita / Davila, Antonio / Issadore, David / Abella, Benjamin S

Resuscitation

2023 Volume 191, Page(s) 109937

Abstract: Aim: Assessment of neurologic injury within the immediate hours following out-of-hospital cardiac arrest (OHCA) resuscitation remains a major clinical challenge. Extracellular vesicles (EVs), small bodies derived from cytosolic contents during injury, ... ...

Abstract	Aim: Assessment of neurologic injury within the immediate hours following out-of-hospital cardiac arrest (OHCA) resuscitation remains a major clinical challenge. Extracellular vesicles (EVs), small bodies derived from cytosolic contents during injury, may provide the opportunity for "liquid biopsy" within hours following resuscitation, as they contain proteins and RNA linked to cell type of origin. We evaluated whether micro-RNA (miRNA) from serologic EVs were associated with post-arrest neurologic outcome. Methods: We obtained serial blood samples in an OHCA cohort. Using novel microfluidic techniques to isolate EVs based on EV surface marker GluR2 (present on excitatory neuronal dendrites enriched in hippocampal tissue), we employed reverse transcription quantitative polymerase chain reaction (RT-qPCR) methods to measure a panel of miRNAs and tested association with dichotomized modified Rankin Score (mRS) at discharge. Results: EVs were assessed in 27 post-arrest patients between 7/3/2019 and 7/21/2022; 9 patients experienced good outcomes. Several miRNA species including miR-124 were statistically associated with mRS at discharge when measured within 6 hours of resuscitation (AUC = 0.84 for miR-124, p < 0.05). In a Kendall ranked correlation analysis, miRNA associations with outcome were not strongly correlated with standard serologic marker measurements, or amongst themselves, suggesting that miRNA provide distinct information from common protein biomarkers. Conclusions: This study explores the associations between miRNAs from neuron-derived EVs (NDEs) and circulating protein biomarkers within 6 hours with neurologic outcome, suggesting a panel of very early biomarker may be useful during clinical care. Future work will be required to test larger cohorts with a broader panel of miRNA species.
MeSH term(s)	Humans ; Feasibility Studies ; MicroRNAs/genetics ; MicroRNAs/metabolism ; Brain ; Biomarkers ; Extracellular Vesicles/genetics ; Extracellular Vesicles/metabolism ; Out-of-Hospital Cardiac Arrest/therapy ; Out-of-Hospital Cardiac Arrest/metabolism ; Brain Injuries
Chemical Substances	MicroRNAs ; Biomarkers
Language	English
Publishing date	2023-08-15
Publishing country	Ireland
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S. ; Research Support, N.I.H., Extramural
ZDB-ID	189901-6
ISSN	1873-1570 ; 0300-9572
ISSN (online)	1873-1570
ISSN	0300-9572
DOI	10.1016/j.resuscitation.2023.109937
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1048: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Improvement in use of best practice in the care of patients with oral mucositis in a comprehensive cancer center in Iran: a best practice implementation case study.

Alizadeh, Mahasti / Moradi, Siavash / Zaboli, Ehsan / Emadian, Seyedeh Fatemeh / Ghorbani, Anahita / Hedayatizadeh Omran, Akbar / Alizadeh Navaei, Reza

JBI evidence implementation

2021 Volume 20, Issue 1, Page(s) 101–110

Abstract: Introduction: Oral mucositis is a common debilitating complication of cancer treatments, particularly chemotherapy and radiation.: Objectives: The purpose of this study was to improve oral mucositis prevention and control among cancer patients ... ...

Abstract	Introduction: Oral mucositis is a common debilitating complication of cancer treatments, particularly chemotherapy and radiation. Objectives: The purpose of this study was to improve oral mucositis prevention and control among cancer patients through the implementation of best practice guidelines in a tertiary referral center in Northern Iran. Methods: A clinical audit design was utilized in this implementation project. A preimplementation audit was conducted against nine best practice criteria for the prevention and treatment of oral mucositis among new cases of cancer patients in November and December 2019. Fifty cancer patients and 20 nurses participated in this phase of the clinical audit. The next step included a facilitated multidisciplinary focus group identifying targeted strategies and implementing them, completed in late December 2019. A postimplementation audit was then conducted on another 50 cancer patients and the same 20 nurses in January and early February 2020. The project utilized the Joanna Briggs Institute Practical Application of Clinical Evidence System and Getting Research into Practice software. Results: The preimplementation audit revealed gaps between the current practice and best practice across eight of the nine criteria. After implementing the targeted strategies, the outcomes improved across most of the criteria in the follow-up audit: 80% increase was observed in compliance of staff education, 100% increase in providing standard oral hygiene protocol in place, 64% increase in carrying out a dental examination and conducting initial oral cavity examination, and also 34% increase in conducting of ongoing oral cavity examination by a dentist, and finally 100% increase in providing preventive and therapeutic oral care regimens in place and oral pain assessment using a validated tool. Conclusion: The results of this project indicate that clinical auditing is an effective approach to the assessment of evidence-based care practices for oral mucositis among new cancer patients. Evidence-based oral mucositis management among cancer patients can be achieved by educating the patients and nursing staff using the newest guidelines and dentists' comprehensive dental and oral hygiene examinations.
MeSH term(s)	Evidence-Based Practice ; Humans ; Iran ; Neoplasms/drug therapy ; Pain Measurement ; Stomatitis/prevention & control ; Tertiary Care Centers
Language	English
Publishing date	2021-08-25
Publishing country	United States
Document type	Journal Article
ISSN	2691-3321
ISSN (online)	2691-3321
DOI	10.1097/XEB.0000000000000292
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

Order via subito

Inter-library loan at ZB MED

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Bonn / Germany

Order via subito

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED