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  1. Article ; Online: Allergic bronchopulmonary aspergillosis causing total lung collapse.

    Ghosh, Kris / Sanders, Bethany Eve

    BMJ case reports

    2012  Volume 2012

    Abstract: Allergic bronchopulmonary aspergillosis (ABPA) is commonly associated with underlying respiratory disease. The authors present the case of a 68-year-old non-smoker, admitted with a possible acute coronary syndrome, who deteriorated in hospital secondary ... ...

    Abstract Allergic bronchopulmonary aspergillosis (ABPA) is commonly associated with underlying respiratory disease. The authors present the case of a 68-year-old non-smoker, admitted with a possible acute coronary syndrome, who deteriorated in hospital secondary to total left lung collapse as demonstrated on chest radiograph. There was no significant history of respiratory disease. Histology from bronchoscopy and lavage indicated lung carcinoma; however biopsy and CT staging demonstrated APBA. This is the first report of lung collapse secondary to ABPA in which initial bronchoscopy suggested underlying carcinoma.
    MeSH term(s) Aged ; Aspergillosis, Allergic Bronchopulmonary/complications ; Aspergillosis, Allergic Bronchopulmonary/diagnosis ; Biopsy ; Bronchoalveolar Lavage ; Bronchoscopy ; Female ; Humans ; Pulmonary Atelectasis/diagnosis ; Pulmonary Atelectasis/etiology ; Radiography, Thoracic ; Tomography, X-Ray Computed
    Language English
    Publishing date 2012-03-08
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr.12.2011.5349
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: An aromatic mystery.

    Reid, James / Balcombe, Nick / Ghosh, Kris

    BMJ case reports

    2010  Volume 2010

    Abstract: A case of antiepileptic hypersensitivity syndrome presenting as an acute septic illness is reported. A 67-year-old man, with a history of essential hypertension (treated with amlodipine) and recently diagnosed nocturnal epilepsy (treated with phenytoin), ...

    Abstract A case of antiepileptic hypersensitivity syndrome presenting as an acute septic illness is reported. A 67-year-old man, with a history of essential hypertension (treated with amlodipine) and recently diagnosed nocturnal epilepsy (treated with phenytoin), presented initially with an acute pneumonic illness with periorbital oedema. This was treated successfully with antibiotics and his phenytoin was changed to carbamazepine due to concerns regarding the periorbital oedema. He was re-admitted the following month with a history of weight loss, rigors, night sweats and high temperatures. Investigations revealed very high inflammatory markers. Despite extensive tests, no source of infection, autoimmune disease or malignancy was identified. The carbamazepine was then stopped and over the next 5 days the patient's symptoms gradually resolved. The patient's haematological and biochemical abnormalities returned to normal and he was discharged home. Since discharge he has been very well with no further sequelae.
    Language English
    Publishing date 2010-02-08
    Publishing country England
    Document type Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr.09.2009.2261
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Diabetes in older people.

    Ghosh, Kris / Sinclair, Alan J

    The Practitioner

    2005  Volume 249, Issue 1675, Page(s) 702–707

    MeSH term(s) Aged ; Aged, 80 and over ; Diabetes Mellitus, Type 2/diagnosis ; Diabetes Mellitus, Type 2/psychology ; Diabetes Mellitus, Type 2/therapy ; Female ; Humans ; Male ; Risk Factors
    Language English
    Publishing date 2005-10
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 124095-x
    ISSN 0032-6518
    ISSN 0032-6518
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Reducing hospital bed use by frail older people: results from a systematic review of the literature.

    Philp, Ian / Mills, Karen A / Thanvi, Bhomraj / Ghosh, Kris / Long, Judith F

    International journal of integrated care

    2013  Volume 13, Page(s) e048

    Abstract: Introduction: Numerous studies have been conducted in developed countries to evaluate the impact of interventions designed to reduce hospital admissions or length of stay (LOS) amongst frail older people. In this study, we have undertaken a systematic ... ...

    Abstract Introduction: Numerous studies have been conducted in developed countries to evaluate the impact of interventions designed to reduce hospital admissions or length of stay (LOS) amongst frail older people. In this study, we have undertaken a systematic review of the recent international literature (2007-present) to help improve our understanding about the impact of these interventions.
    Methods: WE SYSTEMATICALLY SEARCHED THE FOLLOWING DATABASES: PubMed/Medline, PsycINFO, CINAHL, BioMed Central and Kings Fund library. Studies were limited to publications from the period 2007-present and a total of 514 studies were identified.
    Results: A total of 48 studies were included for full review consisting of 11 meta-analyses, 9 systematic reviews, 5 structured literature reviews, 8 randomised controlled trials and 15 other studies. We classified interventions into those which aimed to prevent admission, interventions in hospital, and those which aimed to support early discharge.
    Conclusions: Reducing unnecessary use of acute hospital beds by older people requires an integrated approach across hospital and community settings. A stronger evidence base has emerged in recent years about a broad range of interventions which may be effective. Local agencies need to work together to implement these interventions to create a sustainable health care system for older people.
    Language English
    Publishing date 2013-12-05
    Publishing country England
    Document type Journal Article
    ISSN 1568-4156
    ISSN 1568-4156
    DOI 10.5334/ijic.1148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Stage IV carcinoma of the Bartholin gland managed with primary chemoradiation.

    Downs, Levi S / Ghosh, Kris / Dusenbery, Kathryn E / Cosin, Jonathan A

    Gynecologic oncology

    2002  Volume 87, Issue 2, Page(s) 210–212

    Abstract: Background: Optimal management of carcinoma of the Bartholin gland is not yet defined. Patients with locally advanced disease have historically been managed by radical and, occasionally, exenterative surgery. Although the management of advanced vulvar ... ...

    Abstract Background: Optimal management of carcinoma of the Bartholin gland is not yet defined. Patients with locally advanced disease have historically been managed by radical and, occasionally, exenterative surgery. Although the management of advanced vulvar cancer has shifted toward conservative management with primary chemoradiation, there is limited information on the similar approach to the management of advanced Bartholin's gland carcinoma.
    Case: We present a woman with stage IVA basaloid squamous carcinoma of the Bartholin gland. She was managed with primary chemoradiation in an attempt to spare her the morbidity associated with exenterative surgery. We discuss a rationale for the use of chemoradiation in advanced Bartholin's gland carcinoma.
    Conclusion: Conservative management of advanced carcinoma of the Bartholin gland with primary chemoradiation may be appropriate while sparing patients the sequelae of exenterative surgery.
    MeSH term(s) Adult ; Bartholin's Glands/pathology ; Carcinoma, Squamous Cell/drug therapy ; Carcinoma, Squamous Cell/pathology ; Carcinoma, Squamous Cell/radiotherapy ; Carcinoma, Squamous Cell/surgery ; Combined Modality Therapy ; Female ; Humans ; Neoplasm Staging ; Vulvar Neoplasms/drug therapy ; Vulvar Neoplasms/pathology ; Vulvar Neoplasms/radiotherapy ; Vulvar Neoplasms/surgery
    Language English
    Publishing date 2002-11-21
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 801461-9
    ISSN 1095-6859 ; 0090-8258
    ISSN (online) 1095-6859
    ISSN 0090-8258
    DOI 10.1006/gyno.2002.6787
    Database MEDical Literature Analysis and Retrieval System OnLINE

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