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Article ; Online: Genome Engineering as a Therapeutic Approach in Cancer Therapy: A Comprehensive Review.

Gemayel, Jack / Chebly, Alain / Kourie, Hampig / Hanna, Colette / Mheidly, Kayane / Mhanna, Melissa / Karam, Farah / Ghoussaini, Daniel / Najjar, Paula El / Khalil, Charbel

Advanced genetics (Hoboken, N.J.)

2024  Volume 5, Issue 1, Page(s) 2300201

Abstract: Cancer is one of the foremost causes of mortality. The human genome remains stable over time. However, human activities and environmental factors have the power to influence the prevalence of certain types of mutations. This goes to the excessive ... ...

Abstract Cancer is one of the foremost causes of mortality. The human genome remains stable over time. However, human activities and environmental factors have the power to influence the prevalence of certain types of mutations. This goes to the excessive progress of xenobiotics and industrial development that is expanding the territory for cancers to develop. The mechanisms involved in immune responses against cancer are widely studied. Genome editing has changed the genome-based immunotherapy process in the human body and has opened a new era for cancer treatment. In this review, recent cancer immunotherapies and the use of genome engineering technology are largely focused on.
Language English
Publishing date 2024-02-05
Publishing country United States
Document type Journal Article ; Review
ISSN 2641-6573
ISSN (online) 2641-6573
DOI 10.1002/ggn2.202300201
Database MEDical Literature Analysis and Retrieval System OnLINE

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