LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 34

Search options

  1. Article ; Online: Augusto Giacometti

    Giacometti, Marco

    Quaderni grigionitaliani ; 1168813-0 ; 1016-748X ; 91 ; 2022 ; 1 ; 5

    percorsi svizzeroitaliani

    2022  

    Publishing date 2022-03-01
    Publisher Pro Grigioni Italiano
    Publishing country ch
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article: Laparoscopic trans-cystic common bile duct exploration and treatment of choledocholithiasis in a patient with Roux-en-Y reconstruction after gastrectomy: report of an emergency case.

    Giacometti, Marco / Battafarano, Francesco / Geraci, Orazio / Zonta, Sandro

    Journal of surgical case reports

    2021  Volume 2021, Issue 4, Page(s) rjab144

    Abstract: We present the case of choledocholithiasis with purulent cholangitis treated with laparoscopic approach in a patient with Roux-en-Y reconstruction after total gastrectomy. After cholangiography, the common bile duct was explored with trans-cystic ... ...

    Abstract We present the case of choledocholithiasis with purulent cholangitis treated with laparoscopic approach in a patient with Roux-en-Y reconstruction after total gastrectomy. After cholangiography, the common bile duct was explored with trans-cystic choledochoscopy and the retained stone extracted under direct vision.
    Language English
    Publishing date 2021-04-27
    Publishing country England
    Document type Case Reports
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjab144
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Book ; Thesis: Zur Bewirtschaftung der Steinbockbestände (Capra i. ibex L.)

    Giacometti, Marco

    mit einem geschichtlichen Abriß der Steinbockkolonien im Kanton Graubünden

    1988  

    Author's details Marco Giacometti
    Language German
    Size 114 S. : Ill., graph. Darst.
    Publishing country Switzerland
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Zürich, Univ., Diss., 1988
    HBZ-ID HT004217308
    Database Catalogue ZB MED Nutrition, Environment, Agriculture

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Shelf markLoan statusLocation
    AY 12590 order for loan Geschlossenes Magazin (U2)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: On-Chip Selective Capture and Detection of Magnetic Fingerprints of Malaria.

    Milesi, Francesca / Giacometti, Marco / Coppadoro, Lorenzo Pietro / Ferrari, Giorgio / Fiore, Gianfranco Beniamino / Bertacco, Riccardo

    Sensors (Basel, Switzerland)

    2020  Volume 20, Issue 17

    Abstract: The development of innovative diagnostic tests is fundamental in the route towards malaria eradication. Here, we discuss the sorting capabilities of an innovative test for malaria which allows the quantitative and rapid detection of all malaria species. ... ...

    Abstract The development of innovative diagnostic tests is fundamental in the route towards malaria eradication. Here, we discuss the sorting capabilities of an innovative test for malaria which allows the quantitative and rapid detection of all malaria species. The physical concept of the test exploits the paramagnetic property of infected erythrocytes and hemozoin crystals, the magnetic fingerprints of malaria common to all species, which allows them to undergo a selective magnetophoretic separation driven by a magnetic field gradient in competition with gravity. Upon separation, corpuscles concentrate at the surface of a silicon microchip where interdigitated electrodes are placed in close proximity to magnetic concentrators. The impedance variation proportional to the amount of attracted particles is then measured. The capability of our test to perform the selective detection of infected erythrocytes and hemozoin crystals has been tested by means of capture experiments on treated bovine red blood cells, mimicking the behavior of malaria-infected ones, and suspensions of synthetic hemozoin crystals. Different configuration angles of the chip with respect to gravity force and different thicknesses of the microfluidic chamber containing the blood sample have been investigated experimentally and by multiphysics simulations. In the paper, we describe the optimum conditions leading to maximum sensitivity and specificity of the test.
    MeSH term(s) Animals ; Cattle ; Erythrocytes ; Hemeproteins ; Magnetic Phenomena ; Magnetics ; Malaria/diagnosis ; Physical Phenomena
    Chemical Substances Hemeproteins
    Language English
    Publishing date 2020-09-02
    Publishing country Switzerland
    Document type Letter
    ZDB-ID 2052857-7
    ISSN 1424-8220 ; 1424-8220
    ISSN (online) 1424-8220
    ISSN 1424-8220
    DOI 10.3390/s20174972
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article ; Online: Impedance-Based Rapid Diagnostic Tool for Single Malaria Parasite Detection.

    Giacometti, Marco / Pravettoni, Tommaso / Barsotti, Jonathan / Milesi, Francesca / Figares, Caina de Oliveira / Maspero, Federico / Coppadoro, Lorenzo Pietro / Benevento, Giovanni / Ciardo, Mariagrazia / Alano, Pietro / Fiore, Gianfranco Beniamino / Bertacco, Riccardo / Ferrari, Giorgio

    IEEE transactions on biomedical circuits and systems

    2023  Volume 16, Issue 6, Page(s) 1325–1336

    Abstract: This paper presents a custom, low-cost electronic system specifically designed for rapid and quantitative detection of the malaria parasite in a blood sample. The system exploits the paramagnetic properties of malaria-infected red blood cells (iRBCs) for ...

    Abstract This paper presents a custom, low-cost electronic system specifically designed for rapid and quantitative detection of the malaria parasite in a blood sample. The system exploits the paramagnetic properties of malaria-infected red blood cells (iRBCs) for their magnetophoretic capture on the surface of a silicon chip. A lattice of nickel magnetic micro-concentrators embedded in a silicon substrate concentrates the iRBCs above coplanar gold microelectrodes separated by 3 μm for their detection through an impedance measurement. The sensor is designed for a differential operation to remove the large contribution given by the blood sample. The electronic readout automatically balances the sensor before each experiment and reaches a resolution of 15 ppm in the impedance measurement at 1 MHz allowing a limit of detection of 40 parasite/μl with a capture time of 10 minutes. For better reliability of the results, four sensors are acquired during the same experiment. We demonstrate that the realized platform can also detect a single infected cell in real experimental conditions, measuring human blood infected by Plasmodium falciparum malaria specie.
    MeSH term(s) Animals ; Humans ; Plasmodium falciparum ; Parasites ; Electric Impedance ; Rapid Diagnostic Tests ; Reproducibility of Results ; Silicon ; Malaria/diagnosis ; Malaria/parasitology ; Erythrocytes
    Chemical Substances Silicon (Z4152N8IUI)
    Language English
    Publishing date 2023-02-14
    Publishing country United States
    Document type Journal Article
    ISSN 1940-9990
    ISSN (online) 1940-9990
    DOI 10.1109/TBCAS.2022.3215586
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  6. Article ; Conference proceedings: Sechste Tagung der europäischen Vereinigung für Wildtiererkrankungen in Schweden.

    Giacometti, Marco

    Schweizer Archiv fur Tierheilkunde

    2004  Volume 146, Issue 11, Page(s) 538–539

    Title translation Sixth Congress of the European Wildlife Disease Association in Sweden.
    MeSH term(s) Animal Diseases/epidemiology ; Animal Diseases/prevention & control ; Animals ; Animals, Wild ; Europe/epidemiology ; Veterinary Medicine/organization & administration
    Language German
    Publishing date 2004-11
    Publishing country Switzerland
    Document type Congresses
    ZDB-ID 391726-5
    ISSN 0036-7281
    ISSN 0036-7281
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 500: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  7. Article ; Online: On-chip magnetophoretic capture in a model of malaria-infected red blood cells.

    Giacometti, Marco / Monticelli, Marco / Piola, Marco / Milesi, Francesca / Coppadoro, Lorenzo P / Giuliani, Enrico / Jacchetti, Emanuela / Raimondi, Manuela T / Ferrari, Giorgio / Antinori, Spinello / Fiore, Gianfranco B / Bertacco, Riccardo

    Biotechnology and bioengineering

    2022  Volume 119, Issue 4, Page(s) 1129–1141

    Abstract: The search for new rapid diagnostic tests for malaria is a priority for developing an efficient strategy to fight this endemic disease, which affects more than 3 billion people worldwide. In this study, we characterize systematically an easy-to-operate ... ...

    Abstract The search for new rapid diagnostic tests for malaria is a priority for developing an efficient strategy to fight this endemic disease, which affects more than 3 billion people worldwide. In this study, we characterize systematically an easy-to-operate lab-on-chip, designed for the magnetophoretic capture of malaria-infected red blood cells (RBCs). The method relies on the positive magnetic susceptibility of infected RBCs with respect to blood plasma. A matrix of nickel posts fabricated in a silicon chip placed face down is aimed at attracting infected cells, while healthy cells sediment on a glass slide under the action of gravity. Using a model of infected RBCs, that is, erythrocytes with methemoglobin, we obtained a capture efficiency of about 70% after 10 min in static conditions. By proper agitation, the capture efficiency reached 85% after just 5 min. Sample preparation requires only a 1:10 volume dilution of whole blood, previously treated with heparin, in a phosphate-buffered solution. Nonspecific attraction of untreated RBCs was not observed in the same time interval.
    MeSH term(s) Erythrocytes ; Humans ; Magnetics ; Malaria/diagnosis
    Language English
    Publishing date 2022-01-25
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 280318-5
    ISSN 1097-0290 ; 0006-3592
    ISSN (online) 1097-0290
    ISSN 0006-3592
    DOI 10.1002/bit.28030
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 960: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: The emerging role of neutrophil to lymphocyte ratio in determining colorectal cancer treatment outcomes: a systematic review and meta-analysis.

    Malietzis, George / Giacometti, Marco / Kennedy, Robin H / Athanasiou, Thanos / Aziz, Omer / Jenkins, John T

    Annals of surgical oncology

    2014  Volume 21, Issue 12, Page(s) 3938–3946

    Abstract: Background: There is growing evidence suggesting that the neutrophil to lymphocyte ratio (NLR) can act as an independent predictor of long-term outcomes in patients undergoing treatment for colorectal cancer (CRC). This study aims to systematically ... ...

    Abstract Background: There is growing evidence suggesting that the neutrophil to lymphocyte ratio (NLR) can act as an independent predictor of long-term outcomes in patients undergoing treatment for colorectal cancer (CRC). This study aims to systematically review the role of NLR in predicting survival for patients with CRC undergoing treatments, and to evaluate its utility within a CRC surveillance program.
    Methods: This meta-analysis was performed according to PRISMA guidelines. Outcomes of interest included disease-free survival (DFS) for patients undergoing treatment with curative intent and progression-free survival (PFS) in patients undergoing treatments with palliative intent.
    Results: Thirteen observational cohort studies published from 2007 to 2013 evaluated the role of NLR as a predictor of outcome following treatment for CRC. These included (i) patients undergoing surgery to resect the primary cancer (seven studies); (ii) those undergoing palliative chemotherapy (three studies); and (iii) patients undergoing potentially curative treatments for CRC liver metastases (three studies). When all studies were considered, a high pretreatment NLR independently predicted survival (HR 2.08; 95 % CI 1.64-2.64). A high NLR also predicted significantly poorer survival in each of the three groups. Finally, over a 3-year follow-up period, high NLR became a significant predictor of poor outcome at year 2 (HR 2.76; 95 % CI 2.06-3.69; p < 0.00001) and 3 (HR 2.03; 95 % CI 1.48-2.78; p < 0.0001), but not in the first year of follow-up (HR 1.47; 95 % CI 0.89-2.41; p = 0.13).
    Conclusions: Elevated preoperative NLR is associated with poorer survival in CRC patients undergoing treatment and may have a role in CRC surveillance programs as a means of delivering more personalized cancer care.
    MeSH term(s) Colorectal Neoplasms/pathology ; Colorectal Neoplasms/therapy ; Combined Modality Therapy ; Humans ; Lymphocytes/pathology ; Neutrophils/pathology ; Prognosis
    Language English
    Publishing date 2014-11
    Publishing country United States
    Document type Journal Article ; Meta-Analysis ; Review
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-014-3815-2
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 4042: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article ; Online: A new handheld electromagnetic cortical stimulator for brain mapping during open skull neurosurgery: a feasibility study.

    Buzzi, Jacopo / De Momi, Elena / Baratelli, Francesco Maria / Giacometti, Marco / Fiocchi, Serena / Parazzini, Marta / Ravazzani, Paolo / Ferrigno, Giancarlo

    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference

    2016  Volume 2015, Page(s) 3387–3390

    Abstract: Transcranial magnetic stimulations have provided invaluable tools for investigating nervous system functions in a preoperative context; in this paper we propose an innovative tool to extend the magnetic stimulation to an open skull context as a promising ...

    Abstract Transcranial magnetic stimulations have provided invaluable tools for investigating nervous system functions in a preoperative context; in this paper we propose an innovative tool to extend the magnetic stimulation to an open skull context as a promising approach to map the brain cortex. The present gold standard for intraoperative functional mapping of the brain cortex, the direct brain stimulation, has a low spatial resolution and limited penetration and focusing capabilities. The magnetic stimulatory device that we present, is designed to overcome these limitations, while working with low currents and voltages. In the present work we propose an early study of feasibility, in which the possibility of exploiting a train of fast changing magnetic fields to reach the neuron's current thresholds is investigated. Measurements of electric field intensity at different distances from the coil, showed that the magnetic stimulator realized is capable of delivering an electric field on a loop of wire theoretically sufficient to evoke neuron's action potential, thus showing the approach' feasibility.
    MeSH term(s) Brain/surgery ; Brain Mapping/instrumentation ; Equipment Design ; Feasibility Studies ; Humans ; Models, Theoretical ; Neurons/metabolism ; Neurosurgical Procedures/methods ; Skull ; Transcranial Magnetic Stimulation/instrumentation ; Transcranial Magnetic Stimulation/methods
    Language English
    Publishing date 2016-01-12
    Publishing country United States
    Document type Journal Article
    ISSN 2694-0604
    ISSN (online) 2694-0604
    DOI 10.1109/EMBC.2015.7319119
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article ; Online: A Lab-On-chip Tool for Rapid, Quantitative, and Stage-selective Diagnosis of Malaria.

    Giacometti, Marco / Milesi, Francesca / Coppadoro, Pietro Lorenzo / Rizzo, Alberto / Fagiani, Federico / Rinaldi, Christian / Cantoni, Matteo / Petti, Daniela / Albisetti, Edoardo / Sampietro, Marco / Ciardo, Mariagrazia / Siciliano, Giulia / Alano, Pietro / Lemen, Brigitte / Bombe, Joel / Nwaha Toukam, Marie Thérèse / Tina, Paul Fernand / Gismondo, Maria Rita / Corbellino, Mario /
    Grande, Romualdo / Fiore, Gianfranco Beniamino / Ferrari, Giorgio / Antinori, Spinello / Bertacco, Riccardo

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2021  Volume 8, Issue 14, Page(s) 2004101

    Abstract: Malaria remains the most important mosquito-borne infectious disease worldwide, with 229 million new cases and 409.000 deaths in 2019. The infection is caused by a protozoan parasite which attacks red blood cells by feeding on hemoglobin and transforming ...

    Abstract Malaria remains the most important mosquito-borne infectious disease worldwide, with 229 million new cases and 409.000 deaths in 2019. The infection is caused by a protozoan parasite which attacks red blood cells by feeding on hemoglobin and transforming it into hemozoin. Despite the WHO recommendation of prompt malaria diagnosis, the quality of microscopy-based diagnosis is frequently inadequate while rapid diagnostic tests based on antigens are not quantitative and still affected by non-negligible false negative/positive results. PCR-based methods are highly performant but still not widely used in endemic areas. Here, a diagnostic tool (TMek), based on the paramagnetic properties of hemozoin nanocrystals in infected red blood cells (i-RBCs), is reported on. Exploiting the competition between gravity and magnetic forces, i-RBCs in a whole blood specimen are sorted and electrically detected in a microchip. The amplitude and time evolution of the electrical signal allow for the quantification of i-RBCs (in the range 10-10
    MeSH term(s) Erythrocytes/parasitology ; Evaluation Studies as Topic ; Humans ; Lab-On-A-Chip Devices ; Malaria/diagnosis ; Reproducibility of Results ; Sensitivity and Specificity
    Language English
    Publishing date 2021-05-13
    Publishing country Germany
    Document type Evaluation Study ; Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202004101
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top