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  1. Article ; Online: In Reply to "'Atypical' Anti-GBM Disease: Just Atypical, or Not Anti-GBM Disease at All?"

    Chauveau, Bertrand / Gibier, Jean-Baptiste / Rabant, Marion

    American journal of kidney diseases : the official journal of the National Kidney Foundation

    2024  

    Language English
    Publishing date 2024-04-09
    Publishing country United States
    Document type Letter
    ZDB-ID 604539-x
    ISSN 1523-6838 ; 0272-6386
    ISSN (online) 1523-6838
    ISSN 0272-6386
    DOI 10.1053/j.ajkd.2024.03.011
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Hydroxocobalamin-induced oxalate nephropathy after smoke inhalation.

    Hamdini, Loubna / Ydee, Amandine / Larsen, Samuel / Gibier, Jean-Baptiste / Azar, Raymond / Petit, Vivien

    Journal of nephrology

    2023  Volume 36, Issue 5, Page(s) 1443–1445

    MeSH term(s) Humans ; Hydroxocobalamin/adverse effects ; Smoke Inhalation Injury ; Renal Insufficiency ; Hyperoxaluria ; Smoke ; Oxalates/adverse effects
    Chemical Substances Hydroxocobalamin (Q40X8H422O) ; Smoke ; Oxalates
    Language English
    Publishing date 2023-02-28
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1093991-x
    ISSN 1724-6059 ; 1120-3625 ; 1121-8428
    ISSN (online) 1724-6059
    ISSN 1120-3625 ; 1121-8428
    DOI 10.1007/s40620-023-01592-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Un syndrome néphrotique chez un patient porteur d’une polyarthrite rhumatoïde : à propos d’un cas.

    Daniel, Adrien / Gibier, Jean-Baptiste / Azar, Raymond

    Nephrologie & therapeutique

    2019  Volume 15, Issue 6, Page(s) 461–464

    Abstract: A fifty-one years-old patient with a history of rheumatoid arthritis of recent diagnosis is hospitalized for exploration of a rapidly progressive anasarca state. First analysis discovered an impure nephrotic syndrome (acute renal failure, hematuria) and ... ...

    Title translation A patient with rheumatoid arthritis presenting a nephrotic syndrome: A case report.
    Abstract A fifty-one years-old patient with a history of rheumatoid arthritis of recent diagnosis is hospitalized for exploration of a rapidly progressive anasarca state. First analysis discovered an impure nephrotic syndrome (acute renal failure, hematuria) and massive glomerular proteinuria. Auto-medication by nonsteroidal anti-inflammatory drug was revealed. Renal biopsy showed minimal glomerular disease and acute tubular necrosis. Corticosteroid use permitted a normalization of proteinuria and renal recovery was obtained. Literature review showed renal impairment occurring in rheumatoid polyarthritis. Minimal glomerular disease is rare but can be associated with rheumatoid arthritis. This disease, associated with the use of nonsteroidal anti-inflammatory drug, may be responsible of the patient condition.
    MeSH term(s) Adrenal Cortex Hormones/therapeutic use ; Anti-Inflammatory Agents, Non-Steroidal/adverse effects ; Anti-Inflammatory Agents, Non-Steroidal/therapeutic use ; Anticoagulants/therapeutic use ; Arthritis, Rheumatoid/complications ; Arthritis, Rheumatoid/drug therapy ; Biopsy ; Comorbidity ; Diuretics/therapeutic use ; Drug Therapy, Combination ; Humans ; Male ; Middle Aged ; Nephrosis, Lipoid/diagnosis ; Nephrosis, Lipoid/etiology ; Nephrosis, Lipoid/pathology ; Nephrotic Syndrome/drug therapy ; Nephrotic Syndrome/etiology ; Proteinuria/drug therapy ; Proteinuria/etiology ; Remission Induction
    Chemical Substances Adrenal Cortex Hormones ; Anti-Inflammatory Agents, Non-Steroidal ; Anticoagulants ; Diuretics
    Language French
    Publishing date 2019-10-19
    Publishing country France
    Document type Case Reports ; Journal Article
    ZDB-ID 2229575-6
    ISSN 1872-9177 ; 1769-7255
    ISSN (online) 1872-9177
    ISSN 1769-7255
    DOI 10.1016/j.nephro.2019.04.004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Extracorporeal Photopheresis Reduces Fibrotic and Inflammatory Transcriptomic Biological Marker of Chronic Antibody-mediated Kidney Rejection.

    Lionet, Arnaud / Van Triempon, Marine / Figeac, Martin / Fages, Victor / Gibier, Jean-Baptiste / Provot, François / Maanaoui, Mehdi / Pottier, Nicolas / Cauffiez, Christelle / Glowacki, François

    Transplantation direct

    2024  Volume 10, Issue 3, Page(s) e1587

    Abstract: Background: The benefit of extracorporeal photopheresis on the course of kidney transplant rejection is unknown. The aim of our study was to investigate the variations in transcriptomics on graft biopsies when extracorporeal photopheresis was used to ... ...

    Abstract Background: The benefit of extracorporeal photopheresis on the course of kidney transplant rejection is unknown. The aim of our study was to investigate the variations in transcriptomics on graft biopsies when extracorporeal photopheresis was used to treat chronic humoral rejection after kidney transplantation.
    Methods: We retrospectively analyzed the mRNA expression of 770 genes of interest in graft biopsies performed before and after treatment. Eight patients received an average of 23 extracorporeal photopheresis sessions over 4 mo between the 2 biopsies.
    Results: Transcriptomic analysis of the graft biopsies identified a significant (adjusted
    Conclusions: In patients treated with extracorporeal photopheresis for chronic humoral rejection after renal transplantation, omic analysis of repeated biopsies shows a reduction in fibrotic and inflammatory transcriptomic biologicals markers.
    Language English
    Publishing date 2024-02-16
    Publishing country United States
    Document type Journal Article
    ISSN 2373-8731
    ISSN 2373-8731
    DOI 10.1097/TXD.0000000000001587
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Description of a New Simple and Cost-Effective Molecular Testing That Could Simplify

    Fages, Victor / Bourre, Florentin / Larrue, Romain / Wenzel, Andrea / Gibier, Jean-Baptiste / Bonte, Fabrice / Dhaenens, Claire-Marie / Kidd, Kendrah / Kmoch, Stanislav / Bleyer, Anthony / Glowacki, François / Grunewald, Olivier

    Kidney international reports

    2024  Volume 9, Issue 5, Page(s) 1451–1457

    Abstract: Introduction: Patients with autosomal dominant tubulointerstitial kidney disease (ADTKD) usually present with nonspecific progressive chronic kidney disease (CKD) with mild to negative proteinuria and a family history. ADTKD-: Methods: We developed a ...

    Abstract Introduction: Patients with autosomal dominant tubulointerstitial kidney disease (ADTKD) usually present with nonspecific progressive chronic kidney disease (CKD) with mild to negative proteinuria and a family history. ADTKD-
    Methods: We developed a bioinformatic counting script that can detect specific genetic sequences and count the number of occurrences. We used DNA samples from 27 patients for validation, 11 of them were patients from the Lille University Hospital in France and 16 were from the Wake Forest Hospital, NC. All patients from Lille were tested with an NGS gene panel with our script and all patients from Wake Forest Hospital were tested with the snapshot reference technique. Between January 2018 and February 2023, we collected data on all patients diagnosed with
    Results: A total of 27 samples were tested anonymously by the BROAD Institute reference technique for confirmation and we were able to get a 100% concordance for MUC1 diagnosis. Clinico-biologic characteristics in our cohort were similar to those previously described in ADTKD-
    Conclusion: We describe a new simple and cost-effective method for molecular testing of ADTKD-
    Language English
    Publishing date 2024-02-03
    Publishing country United States
    Document type Journal Article
    ISSN 2468-0249
    ISSN (online) 2468-0249
    DOI 10.1016/j.ekir.2024.01.058
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Correction to: COVID-19-related collapsing glomerulopathy revealing a rare risk variant of APOL1: lessons for the clinical nephrologist.

    Laboux, Timothée / Gibier, Jean-Baptiste / Pottier, Nicolas / Glowacki, François / Hamroun, Aghilès

    Journal of nephrology

    2021  Volume 34, Issue 2, Page(s) 379

    Language English
    Publishing date 2021-04-03
    Publishing country Italy
    Document type Published Erratum
    ZDB-ID 1093991-x
    ISSN 1724-6059 ; 1120-3625 ; 1121-8428
    ISSN (online) 1724-6059
    ISSN 1120-3625 ; 1121-8428
    DOI 10.1007/s40620-021-01037-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Nephrology picture: intraglomerular metastases, an exceptional cause of glomerulonephritis.

    Hamroun, Aghilès / Lenain, Rémi / Gibier, Jean-Baptiste / Maanaoui, Mehdi / Lionet, Arnaud

    Journal of nephrology

    2021  Volume 35, Issue 1, Page(s) 361–362

    MeSH term(s) Glomerulonephritis/etiology ; Glomerulonephritis/pathology ; Humans ; Kidney Glomerulus/pathology ; Nephrology
    Language English
    Publishing date 2021-03-09
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1093991-x
    ISSN 1724-6059 ; 1120-3625 ; 1121-8428
    ISSN (online) 1724-6059
    ISSN 1120-3625 ; 1121-8428
    DOI 10.1007/s40620-021-00999-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: COVID-19-related collapsing glomerulopathy revealing a rare risk variant of APOL1: lessons for the clinical nephrologist.

    Laboux, Timothée / Gibier, Jean-Baptiste / Pottier, Nicolas / Glowacki, François / Hamroun, Aghilès

    Journal of nephrology

    2021  Volume 34, Issue 2, Page(s) 373–378

    MeSH term(s) Apolipoprotein L1/metabolism ; Biomarkers/metabolism ; COVID-19/complications ; COVID-19/epidemiology ; Glomerulosclerosis, Focal Segmental/diagnosis ; Glomerulosclerosis, Focal Segmental/etiology ; Glomerulosclerosis, Focal Segmental/metabolism ; Humans ; Kidney Glomerulus/pathology ; Male ; Middle Aged ; Nephrologists ; Pandemics ; Risk Factors ; SARS-CoV-2
    Chemical Substances APOL1 protein, human ; Apolipoprotein L1 ; Biomarkers
    Language English
    Publishing date 2021-02-06
    Publishing country Italy
    Document type Case Reports ; Letter
    ZDB-ID 1093991-x
    ISSN 1724-6059 ; 1120-3625 ; 1121-8428
    ISSN (online) 1724-6059
    ISSN 1120-3625 ; 1121-8428
    DOI 10.1007/s40620-020-00935-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Recognition of intraglomerular histological features with deep learning in protocol transplant biopsies and their association with kidney function and prognosis.

    Farhat, Imane / Maréchal, Elise / Calmo, Doris / Ansart, Manon / Paindavoine, Michel / Bard, Patrick / Tarris, Georges / Ducloux, Didier / Felix, Sophie Adrian / Martin, Laurent / Tinel, Claire / Gibier, Jean-Baptiste / Funes de la Vega, Mathilde / Rebibou, Jean-Michel / Bamoulid, Jamal / Legendre, Mathieu

    Clinical kidney journal

    2024  Volume 17, Issue 2, Page(s) sfae019

    Abstract: Background: The Banff Classification may not adequately address protocol transplant biopsies categorized as normal in patients experiencing unexplained graft function deterioration. This study seeks to employ convolutional neural networks to automate ... ...

    Abstract Background: The Banff Classification may not adequately address protocol transplant biopsies categorized as normal in patients experiencing unexplained graft function deterioration. This study seeks to employ convolutional neural networks to automate the segmentation of glomerular cells and capillaries and assess their correlation with transplant function.
    Methods: A total of 215 patients were categorized into three groups. In the Training cohort, glomerular cells and capillaries from 37 patients were manually annotated to train the networks. The Test cohort (24 patients) compared manual annotations vs automated predictions, while the Application cohort (154 protocol transplant biopsies) examined predicted factors in relation to kidney function and prognosis.
    Results: In the Test cohort, the networks recognized histological structures with Precision, Recall, F-score and Intersection Over Union exceeding 0.92, 0.85, 0.89 and 0.74, respectively. Univariate analysis revealed associations between the estimated glomerular filtration rate (eGFR) at biopsy and relative endothelial area (r = 0.19,
    Conclusion: This study automated the measurement of intraglomerular cells and capillaries. Our results suggest that the precise segmentation of endothelial and epithelial cells may serve as a potential future marker for the risk of graft loss.
    Language English
    Publishing date 2024-02-02
    Publishing country England
    Document type Journal Article
    ZDB-ID 2655800-2
    ISSN 2048-8513 ; 2048-8505
    ISSN (online) 2048-8513
    ISSN 2048-8505
    DOI 10.1093/ckj/sfae019
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Automatic quantification method of eosinophilic degranulation in tissues: Application for the study of eosinophilic disorders.

    Dezoteux, Frédéric / Bongiovanni, Antonino / Tardivel, Meryem / Dendooven, Arnaud / Gibier, Jean-Baptiste / Mortuaire, Geoffrey / Audry, Solène / Gevaert, Marie-Hélène / Van Poucke, Nicolas / Anglo, Emilie / Lefèvre, Guillaume / Staumont-Sallé, Delphine

    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology

    2023  Volume 53, Issue 8, Page(s) 862–865

    MeSH term(s) Humans ; Eosinophils ; Cell Degranulation
    Language English
    Publishing date 2023-04-18
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 645204-8
    ISSN 1365-2222 ; 0954-7894 ; 0960-2178
    ISSN (online) 1365-2222
    ISSN 0954-7894 ; 0960-2178
    DOI 10.1111/cea.14323
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