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  1. Article: Incidence, mortality and survival in cutaneous melanoma.

    Giblin, A-V / Thomas, J M

    Journal of plastic, reconstructive & aesthetic surgery : JPRAS

    2007  Volume 60, Issue 1, Page(s) 32–40

    Abstract: Cutaneous melanoma remains a challenge despite increased levels of awareness, education and targeted health policies. Worldwide incidence rates for cutaneous melanoma have risen faster than those for any other malignancy in Caucasian populations over the ...

    Abstract Cutaneous melanoma remains a challenge despite increased levels of awareness, education and targeted health policies. Worldwide incidence rates for cutaneous melanoma have risen faster than those for any other malignancy in Caucasian populations over the last 30 years. Despite improving survival rates (defined as the ratio of those who survive the disease against incidence) over this period, mortality rates, generally, have continued to climb. Mortality from melanoma is greater than that caused by all other types of skin cancer, especially in men. In Britain the percentage of increase in the male age standardised mortality rate surpassed that of all other malignancies assessed (1993-2002) by Cancer Research UK. A literature-based study was conducted with review of publications identified through Medline and EMBase, 1980-December 2005, databases. We present a review of the current literature on incidence, mortality and survival rates of melanoma including a discussion on the aetiological factors, behaviour modification associated with public education campaigns and recent health policies and the effect these are having on melanoma figures. It is likely that any fall in mortality rates from melanoma in the near future will be secondary to early detection. Changes resulting from primary prevention are unlikely to be noticeable for several decades.
    MeSH term(s) Adolescent ; Adult ; Age Distribution ; Aged ; Aged, 80 and over ; Australasia ; Europe/epidemiology ; Female ; Health Education ; Humans ; Incidence ; Male ; Melanoma/epidemiology ; Melanoma/etiology ; Melanoma/mortality ; Middle Aged ; Sex Distribution ; Skin Neoplasms/epidemiology ; Skin Neoplasms/etiology ; Skin Neoplasms/mortality ; United States/epidemiology
    Language English
    Publishing date 2007
    Publishing country Netherlands
    Document type Journal Article ; Review
    ZDB-ID 2217750-4
    ISSN 1878-0539 ; 1748-6815 ; 0007-1226
    ISSN (online) 1878-0539
    ISSN 1748-6815 ; 0007-1226
    DOI 10.1016/j.bjps.2006.05.008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Dermatologists should exert a greater influence over sentinel lymph node biopsy for melanoma in the U.K.

    Thomas, J Meirion / Giblin, A V

    The British journal of dermatology

    2005  Volume 152, Issue 1, Page(s) 176–177

    MeSH term(s) Humans ; Lymphatic Metastasis ; Melanoma/secondary ; Randomized Controlled Trials as Topic ; Referral and Consultation ; Sentinel Lymph Node Biopsy ; Skin Neoplasms/pathology
    Language English
    Publishing date 2005-01
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 80076-4
    ISSN 1365-2133 ; 0007-0963
    ISSN (online) 1365-2133
    ISSN 0007-0963
    DOI 10.1111/j.1365-2133.2005.06405.x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The significance of melanoma micrometastases in the sentinel lymph node.

    Giblin, A-V / Hayes, A J / Thomas, J M

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2005  Volume 31, Issue 10, Page(s) 1103–1104

    MeSH term(s) Humans ; Lymph Nodes/pathology ; Lymphatic Metastasis ; Melanoma/mortality ; Melanoma/pathology ; Neoplasm Staging ; Prognosis ; Sentinel Lymph Node Biopsy ; Skin Neoplasms/mortality ; Skin Neoplasms/pathology ; Survival Analysis ; Tumor Burden
    Language English
    Publishing date 2005-12
    Publishing country England
    Document type Editorial
    ZDB-ID 632519-1
    ISSN 0748-7983
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2005.06.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Pyogenic granuloma - the quest for optimum treatment: audit of treatment of 408 cases.

    Giblin, A V / Clover, A J P / Athanassopoulos, A / Budny, P G

    Journal of plastic, reconstructive & aesthetic surgery : JPRAS

    2007  Volume 60, Issue 9, Page(s) 1030–1035

    Abstract: Pyogenic granuloma is a common, acquired, benign vascular lesion of skin and mucous membranes which may occasionally present intravascularly or subcutaneously. Pyogenic granuloma occur in all age groups and although they may eventually regress, removal ... ...

    Abstract Pyogenic granuloma is a common, acquired, benign vascular lesion of skin and mucous membranes which may occasionally present intravascularly or subcutaneously. Pyogenic granuloma occur in all age groups and although they may eventually regress, removal of unsightly, bleeding or uncomfortably positioned lesions is usually sought before this takes place. This is a retrospective study of 408 cases of pyogenic granuloma that were analysed by the Stoke Mandeville Histopathology laboratory between 1994 and 2004. This study was carried out to review the sex, age and anatomic distribution of the lesions and to assess the most successful form of treatment on the basis of recurrence risk and other measures such as aesthetic result, acceptability and appropriateness of the procedure with respect to the patient. There was a slight male preponderance especially among children. The exception to this was lesions on mucous membranes, which were more common in women. Head and neck was the most common anatomical location, in particular the cheek and intraoral locations. Fewest recurrences were noted following excision and direct closure although all techniques investigated showed an acceptably low recurrence rate. Whatever technique is used it must yield material for histopathological analysis to ensure the exclusion of differential diagnoses.
    MeSH term(s) Adolescent ; Adult ; Age Distribution ; Aged ; Aged, 80 and over ; Child ; Child, Preschool ; Facial Dermatoses/pathology ; Facial Dermatoses/surgery ; Female ; Granuloma, Pyogenic/pathology ; Granuloma, Pyogenic/surgery ; Humans ; Infant ; Lower Extremity/pathology ; Lower Extremity/surgery ; Male ; Medical Audit ; Middle Aged ; Recurrence ; Retrospective Studies ; Skin Diseases/pathology ; Skin Diseases/surgery ; Treatment Outcome ; Upper Extremity/pathology ; Upper Extremity/surgery
    Language English
    Publishing date 2007
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2217750-4
    ISSN 1878-0539 ; 1748-6815 ; 0007-1226
    ISSN (online) 1878-0539
    ISSN 1748-6815 ; 0007-1226
    DOI 10.1016/j.bjps.2006.10.018
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Mortality and pulmonary complications in patients undergoing surgery with perioperative SARS-CoV-2 infection

    Nepogodiev D. / Bhangu A. / Glasbey J.C. / Li E. / Omar O.M. / Simoes J.F. / Abbott T.E. / Alser O. / Arnaud A.P. / Bankhead-Kendall B.K. / Breen K.A. / Cunha M.F. / Davidson G.H. / Di Saverio S. / Gallo G. / Griffiths E.A. / Gujjuri R.R. / Hutchinson P.J. / Kaafarani H.M. /
    Lederhuber H. / Loffler M.W. / Mashbari H.N. / Minaya-Bravo A. / Morton D.G. / Moszkowicz D. / Pata F. / Tsoulfas G. / Venn M.L. / Cox D. / Roslani A.C. / Alakaloko F. / de Vries J.-P.P. / Aaraj M.A. / Abbott S.J. / Abdalla M.O. / Abdelaal A.S. / Ademuyiwa A.O. / Aherne T.M. / Ali O.M. / Alkadeeki G.Z. / Almeida A.C. / Alrahawy M.M. / Ambler G.K. / Alameer E. / Andreani S.M. / De Andres-Asenjo B. / Antonanzas L.L. / Aoun S.G. / Ashoush F.M. / Augestad K.M. / Avellana R.B. / Ayeni F.A. / Ayorinde J.O. / Babu B.H. / Baig M.M. / Bajomo O.M. / Baker O.J. / Baker M.P. / Baldwin A.J. / Ban V.S. / Baron R.D. / Barranquero A.G. / Barry C.P. / DI Bartolomeo A. / Bass G.A. / Bath M.F. / Batjer H.H. / Beamish A.J. / Belgaumkar A.P. / Bence M.N. / Benson R.A. / Bernal-Sprekelsen J.C. / Bhama A.R. / Bhavaraju A.V. / Biffl W.L. / Blundell C.M. / Boddy A.P. / Borgstein A.B. / Bosanquet D.C. / Bosch K.D. / Bouhuwaish A.E. / Bozkurt M.A. / Brathwaite C.E. / Brown B.C. / Brown O.D. / Brown A.K. / Buarque I.L. / Bueno-Canones A.D. / Bulugma M.R. / Burke J.R. / Byrne M.H. / Cagigal-Ortega E.P. / Callcut R.A. / DI Candido F. / Canova M.E. / Carlos W.J. / Caruana E.J. / Cato L.D. / Catton A.B. / Ceretti A.P. / Chase T.J. / Chiara F.D. / Chowdhury A.H. / Chung E.A. / Cicerchia P.M. / Clough E.C. / Coleman N.L. / Collins C.G. / Collins M.L. / Colonna E.T. / Comini L.V. / Coughlin P.A. / Cruzado L.F.-G. / Davidson B.R. / Davies R.J. / Davies E.J. / Davis N.F. / Dawson B.E. / Dean B.J. / Delgado M.G.-C. / Diaz J.J. / Dickson K.E. / Diez-Alonso M.M. / Dixon J.R. / Doe M.J. / Drake T.D. / Drake F.T. / Duffy J.P. / Dunne D.F. / Dunne N.J. / Duran-Munoz-Cruzado V.M. / Durst A.Z. / Eardley N.J. / Edwards J.G. / Elfallal A.H. / Elfiky M.M. / Elliott J.A. / Emile S.H. / Emslie K.M. / Endorf F.W. / Engel J.L. / Enjuto D.T. / Etchill E.W. / Evans J.P. / Fahey B.A. / Faria C.S. / Feo C.V. / Ferguson H.J. / Fernandez B.D. / Fernandez A.G. / Fernandez A.J. / Fernandez-Pacheco B.C. / Fitzgerald J.E. / Fonsi G.B. / Font R.F. / Fowler A.L. / Fretwell K.R. / Fructuoso L.S. / Fusai G.K. / Garcia M.H. / Garcia-Urena M.A. / Gill C.K. / Gisbertz S.S. / Del Giudice R. / Giuffrida M.C. / Di Giuseppe M. / Gomez M.F. / Guariglia C.A. / Hainsworth A.J. / Hall B.J. / Hall J.R. / Hammond J.S. / Haqqani M.H. / Harrison E.M. / Hazelton J.P. / van Heinsbergen M. / Hill A.D. / Hing C.B. / Hirji S.A. / Ho M.W. / Holbrook C.M. / Holme T.J. / Hopkins J.C. / Hopkinson D.N. / Hossain F.S. / Hudson V.E. / Hughes J.L. / Hwang E.S. / Ibrahim M.A. / Isolani S.M. / Jenkinson M.D. / Jenny H.E. / Jeyaretna D.S. / Jones R.P. / Jones A.P. / Jonker P.K. / Jonsson M.L. / Joyce D.P. / Kalkwarf K.J. / Kamarajah S.K. / El Kassas M. / Kavanagh D.O. / Keatley J.M. / Khalefa M.A. / Khan J.S. / Kirmani B.H. / Kisiel A.P. / Kouris S.M. / Kowal M.R. / Labib P.L. / Larkin J.O. / Lauscher J.C. / Leclercq W.K. / Ledesma F.S. / Leite-Moreira A.M. / Leung E.Y. / Lewis S.E. / Lima M.J. / Lin D.J. / Liu H.H. / Lowery A.J. / Lozano S.M. / Luney C.R. / Maia M.M. / Mariani N.M. / Marino M.V. / Marra A.A. / Marsh C.L. / Martin R.C. / McCluney S.J. / McIntyre R.C. / Mckay S.C. / McKevitt K.L. / Meagher A.D. / Mehdi M.Q. / Mehigan B.J. / Gonzalez-De Miguel M. / De Miguel-Ardevines M.-C. / Mills S.J. / Mohan H.M. / Moir J.A. / Monson J.R. / Monteiro J.M. / Montella M.T. / Montesinos C.S. / Morgom M.M. / Moura F.S. / Muguerza J.M. / Murphy S.H. / De Nardi P. / Naumann D.N. / Neary P.C. / Neely D.T. / Ng-Kamstra J.S. / Ngu A.W. / Nguyen T.A. / Nita G.E. / Nunes Q.M. / Nygaard R.M. / O'Meara L.B. / O'Neill J.R. / Okafor B.U. / Olson S.A. / Oo A.Y. / Ormazabal P.C. / Osorio A.L. / Pachl M.J. / Parry J.T. / Patel P.K. / Perez-Sanchez L.E. / Pevidal A.N. / Pezzuto A.P. / Philp M.M. / Pinkney T.D. / Pollok J.M. / Povey M.G. / Poza A.A. / Rajgor A.D. / Rao J.N. / Raptis D.A. / Rice H.E. / Ridgway P.F. / Rivas A.M. / Rodriguez-Sanjuan J.C. / Rogers L.J. / Da Roit A. / Rollett R.A. / Romera J.L. / Rooney S.M. / Roxo V.I. / Le Roy B. / Rubio E.E. / Ruiz C.C. / Ruiz M.L. / Ryan E.J. / Saad A.R. / Saeed S.A. / Salama H.A. / Salamah A.A. / Sampietro G.M. / Sarma D.R. / Schaffer K.B. / Schnitzbauer A.A. / Scurrah R.J. / Serevina O.L. / Serralheiro P.A. / Sewards J.M. / Shackcloth M.J. / Shaw A.V. / Sheel A.R. / Sica G.S. / De Simone V. / Singh A.A. / Singh R.P. / Skelly B.L. / Smith H.G. / Sohail A.H. / Spalding D.R. / Springford L.R. / Ssentongo A.E. / Steinkamp P.J. / Stevens K.A. / Stewart G.D. / Stylianides N.A. / Sullivan T.B. / Taher A.S. / Tamimy M.S. / Tang A.M. / Tebala G.D. / Tejero-Pintor F.J. / Thaha M.A. / Thomas A.J. / De Toma G. / La Torre F. / Torres A.J. / Townshend D.N. / Trout I.M. / Tucker S.C. / Ubhi H.K. / Vega V.A. / Velmahos G.C. / Velopulos C.G. / Viswanath Y.K. / Vivas A.A. / Wade R.G. / Wadley M.S. / Wall J.J. / Walters A.M. / Warren O.J. / Weerasinghe C.K. / Wilkin R.J. / Williams K.J. / Winter S.C. / Wormald J.C. / Wright F.L. / Xyda S.E. / Young A.L. / Youssef M.M. / Yousuf F.B. / El Youzouri H. / Zappa M.A. / Abate E. / Abdalaziz H. / Abdelkarim M. / Abdou H. / Aboelkassem-Ibrahim A. / Abuown A. / Acebes-Garcia F. / Acharya M. / Adamina M. / Addae-Boateng E. / Aftab R. / Agarwal A. / Aguilar J. / Ahmed Y. / Aitken E. / Al-Azzawi M. / Al-Embideen S. / Al-Masri M. / Al-Najjar H. / Al-Sukaini A. / Alam R. / Alderson D. / Aliyeva Z. / Aljanadi F. / Almasri M. / Alonso-Ortuno P. / Altintoprak F. / Amira G. / Amjad R. / Anania G. / Andabaka T. / Angelou D. / Annamalai S. / Annessi V. / Anthoney J. / Anwar S. / Anwer M. / Aragon-Chamizo J. / Ardito A. / Arigoni M. / Armao T. / Arminio A. / Armstrong L. / Arnaud A. / Asaad P. / Ashcroft J. / Ashmore C. / Asqalan A. / Asti E. / Aubry E. / Aytac E. / Ayuso-Herrera E. / Baeza M. / Bailon-Cuadrado M. / Bakmaz B. / Baldi C. / Baldini E. / Baldo S. / Ballabio M. / Baloyiannis I. / Baltazar G. / Bambina F. / Bandiera A. / Barlow E. / Barmasse R. / Barmpagianni C. / Baronio G. / Barra F. / Bartsch A.-M. / Basgaran A. / Basha A. / Bashkirova V. / Bastazza M. / Baumber R. / Belcher E. / Belvedere A. / Benitez-Linero I. / Bergeat D. / Bernasconi M. / Bhalla A. / Bhutiani N. / Bianco F. / Bisagni P. / Blake I. / Blanco-Colino R. / Blazquez-Martin A. / Boal M. / Bonavina L. / Bonavina G. / Bond-Smith G. / Booth K. / Borges F. / Borghi F. / Bouchagier K. / Bourke G. / Boyle E. / Brachini G. / Brain J. / Brar A. / Breckles L. / Bretagnol F. / Brixton G. / Bruzzaniti P. / Bueser T. / Burnside N. / Caballero A. / Calcerrada-Alises E. / Callahan M. / Camarero E. / Campagnaro T. / Campanelli M. / Candiani M. / Cantalejo-Diaz M. / Cao H. / Capelli P. / Capizzi V. / Carcano G. / Carissimi F. / Carlini M. / Carlucci M. / Carmichael H. / Carrasco M. / Carrillo M. / Carvello M. / Casati M. / Castoro C. / Catalan V. / Cavaleiro S. / Cellerino P. / Centinaio G. / Cernei C. / Cerro C. / Cervellera M. / Chakrabortee S. / Chamberlain S. / Chan J. / Chang G. / Chaudhry D. / Chebaro A. / Chen D. / Chetty G. / Chia Z. / Chiappini A. / Chiarugi M. / Chidambaram S. / Chiozza M. / Cholewa H. / Chong C. / Choolani-Bhojwani E. / Christoforidis D. / Chui K. / Chung C. / Cirillo B. / Citterio D. / Clermidi P. / Coccolini F. / Colletti G. / Compagnoni B. / Concepcion-Martin V. / Confalonieri M. / Connolly H. / Conso C. / Conti L. / Cooper Z. / Cordera F. / Corral J. / Costa M. / Costanzi A. / Cotsoglou C. / Cozza V. / Cuming T. / Curtis M. / Cuschieri J. / D'Agruma M. / D'Andrea G. / Daliya P. / Dare O. / Darko E. / Day A. / Dehal A. / Dehart D. / Delgado-Oliver E. / Denning M. / Desai A. / Desender L. / Dester S. / Diaz-Garcia A. / Diaz-Pena P. / Dousset B. / Doussot A. / Duchateau N. / Duff S. / Dunning J. / Duque-Mallen V. / Dziakova J. / Egan B. / Egan R. / El-Ali A. / Elfeki H. / Elhadi M. / Eljareh M. / Elkady R. / Elkhafeefi F. / Elmore U. / Elmoslemany T. / Emmerson O. / Enemosah I. / English C. / English W. / Escartin J. / Estaire-Gomez M. / Evans L. / Evans J. / Exley R. / Fabbri N. / Falco G. / Familiari P. / Fancellu A. / Farik S. / Farrell T. / Fehervari M. / Fell A. / Fernandez-Camunas A. / Fernandez-Marin R. / Fernandez-Martinez M. / Ferrara F. / Ferrari G. / Ferrero S. / Findlay L. / Fiore M. / Fiori E. / Flatman M. / Flindall I. / Flor B. / Fontana T. / Ford S. / Ford D. / Forlani S. / Francone E. / Frattaruolo C. / Frio F. / Gagliano A. / Gagliardi F. / Gahunia S. / Gaino F. / Gala T. / Galfrascoli E. / Galimberti L. / Gallagher P. / Galleano R. / Galvan-Perez A. / Gammeri E. / Ganau M. / Garces-Garcia R. / Garulli G. / Gascon-Ferrer I. / Gattolin A. / Gaujoux S. / Gentilli S. / Georgiades F. / Ghanbari A. / Ghosh D. / Giacometti M. / Giblin A.-V. / Gilbert C. / Gimenez C. / Giorgakis E. / Gipponi M. / Glen P. / Goatly G. / Gobatti D. / Godbole C. / Gohil K. / Gomez M. / Gomez-Rosado J.-C. / Gonullu E. / Gonzalez-Gonzalez E. / Gordini L. / Gracia I. / Gracia-Roche C. / Granieri S. / Green S. / Grivon M. / Grove T. / Guaglio M. / Guaitoli E. / Guglielmi A. / Guha S. / 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G.S. / Mateo-Sierra O. / Martinez-Perez C. / Serrano Gonzalez J. / Hernandez Bartolome M.A. / Diaz Perez D. / Gutierrez Samaniego M. / Galindo Jara P. / Sharma N. / Smart N.J. / Keller D.S.

    an international cohort study

    2020  

    Abstract: Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and ... ...

    Abstract Background: The impact of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) on postoperative recovery needs to be understood to inform clinical decision making during and after the COVID-19 pandemic. This study reports 30-day mortality and pulmonary complication rates in patients with perioperative SARS-CoV-2 infection. Methods: This international, multicentre, cohort study at 235 hospitals in 24 countries included all patients undergoing surgery who had SARS-CoV-2 infection confirmed within 7 days before or 30 days after surgery. The primary outcome measure was 30-day postoperative mortality and was assessed in all enrolled patients. The main secondary outcome measure was pulmonary complications, defined as pneumonia, acute respiratory distress syndrome, or unexpected postoperative ventilation. Findings: This analysis includes 1128 patients who had surgery between Jan 1 and March 31, 2020, of whom 835 (74·0%) had emergency surgery and 280 (24·8%) had elective surgery. SARS-CoV-2 infection was confirmed preoperatively in 294 (26·1%) patients. 30-day mortality was 23·8% (268 of 1128). Pulmonary complications occurred in 577 (51·2%) of 1128 patients; 30-day mortality in these patients was 38·0% (219 of 577), accounting for 81·7% (219 of 268) of all deaths. In adjusted analyses, 30-day mortality was associated with male sex (odds ratio 1·75 [95% CI 1·28–2·40], p<0·0001), age 70 years or older versus younger than 70 years (2·30 [1·65–3·22], p<0·0001), American Society of Anesthesiologists grades 3–5 versus grades 1–2 (2·35 [1·57–3·53], p<0·0001), malignant versus benign or obstetric diagnosis (1·55 [1·01–2·39], p=0·046), emergency versus elective surgery (1·67 [1·06–2·63], p=0·026), and major versus minor surgery (1·52 [1·01–2·31], p=0·047). Interpretation: Postoperative pulmonary complications occur in half of patients with perioperative SARS-CoV-2 infection and are associated with high mortality. Thresholds for surgery during the COVID-19 pandemic should be higher than during normal practice, particularly in men aged 70 years and older. Consideration should be given for postponing non-urgent procedures and promoting non-operative treatment to delay or avoid the need for surgery. Funding: National Institute for Health Research (NIHR), Association of Coloproctology of Great Britain and Ireland, Bowel and Cancer Research, Bowel Disease Research Foundation, Association of Upper Gastrointestinal Surgeons, British Association of Surgical Oncology, British Gynaecological Cancer Society, European Society of Coloproctology, NIHR Academy, Sarcoma UK, Vascular Society for Great Britain and Ireland, and Yorkshire Cancer Research.
    Keywords Adult ; Aged ; Betacoronavirus ; Coronavirus Infections ; Elective Surgical Procedures ; Emergency Medical Services ; Female ; Hospital Mortality ; Humans ; Male ; Middle Aged ; Pandemics ; Pneumonia ; Viral ; Postoperative Complications ; Respiratory Tract Diseases ; Retrospective Studies ; Surgical Procedures ; Operative ; Young Adult ; covid19
    Subject code 610 ; 616
    Language English
    Publishing country it
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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