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  1. Book ; Online ; Thesis: Assoziationsuntersuchung von Polymorphismen des CTLA4- und PTPN22-Gens mit Morbus Menière

    Clement, Sarah [Verfasser] / Giegling, Ina [Akademischer Betreuer]

    2023  

    Author's details Sarah Clement ; Betreuer: Ina Giegling
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  2. Book ; Online ; Thesis: Genetischer Zusammenhang von Morbus Menière und Polymorphismen der Aquaporingene 3, 4 und 5

    Kalb, Elena [Verfasser] / Giegling, Ina [Akademischer Betreuer]

    2022  

    Author's details Elena Kalb ; Betreuer: Ina Giegling
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  3. Book ; Online ; Thesis: Eine Gen- und Gen-Set-basierte genomweite Assoziationsstudie zum Morbus Menière

    Bauernschmitt, Franz [Verfasser] / Giegling, Ina [Akademischer Betreuer]

    2022  

    Author's details Franz Bauernschmitt ; Betreuer: Ina Giegling
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  4. Book ; Online ; Thesis: Assoziationsstudie von migräneassoziierten Genvarianten mit Vestibulärer Migräne und peripher vestibulären Schwindelerkrankungen

    Strunz, Simon [Verfasser] / Giegling, Ina [Akademischer Betreuer]

    2022  

    Author's details Simon Strunz ; Betreuer: Ina Giegling
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  5. Article: Proton Magnetic Resonance Spectroscopy in Common Dementias-Current Status and Perspectives.

    Maul, Stephan / Giegling, Ina / Rujescu, Dan

    Frontiers in psychiatry

    2020  Volume 11, Page(s) 769

    Abstract: Dementia occurs mainly in the elderly and is associated with cognitive decline and impairment of activities of daily living. The most common forms of dementia are Alzheimer's disease (AD), vascular dementia (VD), dementia with Lewy bodies (DLB), and ... ...

    Abstract Dementia occurs mainly in the elderly and is associated with cognitive decline and impairment of activities of daily living. The most common forms of dementia are Alzheimer's disease (AD), vascular dementia (VD), dementia with Lewy bodies (DLB), and frontotemporal dementia (FTD). To date, there are no causal options for therapy, but drug and non-drug treatments can positively modulate the course of the disease. Valid biomarkers are needed for the earliest possible and reliable diagnosis, but so far, such biomarkers have only been established for AD and require invasive and expensive procedures. In this context, proton magnetic resonance spectroscopy (
    Language English
    Publishing date 2020-08-06
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2564218-2
    ISSN 1664-0640
    ISSN 1664-0640
    DOI 10.3389/fpsyt.2020.00769
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Book ; Online ; Thesis: Der Einfluss von Polymorphismen in den spannungsabhängigen Kaliumkanalgenen KCNE1 und KCNE3 auf Morbus Menière

    Schmude, Inga Ann-Cathrin [Verfasser] / Giegling, Ina [Akademischer Betreuer]

    2020  

    Author's details Inga Ann-Cathrin Schmude ; Betreuer: Ina Giegling
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  7. Book ; Online ; Thesis: HTR3A als Kandidatengen für phobischen Schwankschwindel durch die Assoziation von Polymorphismen mit der Neurotizismusausprägung

    Bucher, Katharina [Verfasser] / Giegling, Ina [Akademischer Betreuer]

    2020  

    Author's details Katharina Bucher ; Betreuer: Ina Giegling
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitätsbibliothek der Ludwig-Maximilians-Universität
    Publishing place München
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  8. Book ; Online ; Thesis: Traumatisierung und psychose-ähnliche Symptome bei Patienten mit paranoider Schizophrenie, emotional instabiler Persönlichkeitsstörung und Gesunden

    Haase, Elisa [Verfasser] / Watzke, Stefan [Gutachter] / Giegling, Ina [Gutachter] / Strauß, Bernhard [Gutachter]

    2020  

    Author's details Elisa Haase ; Gutachter: Stefan Watzke, Ina Giegling, Bernhard Strauß
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitäts- und Landesbibliothek Sachsen-Anhalt
    Publishing place Halle (Saale)
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  9. Book ; Online ; Thesis: Paranoides Denken

    Leonhardt, Anna [Verfasser] / Watzke, Stefan [Gutachter] / Giegling, Ina [Gutachter] / Bergemann, Niels [Gutachter]

    Assoziation mit kognitiven Leistungen bei Patienten mit Schizophrenie und gesunden Kontrollen

    2020  

    Author's details Anna Leonhardt ; Gutachter: Stefan Watzke, Ina Giegling, Niels Bergemann
    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universitäts- und Landesbibliothek Sachsen-Anhalt
    Publishing place Halle (Saale)
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  10. Article ; Online: Genetics of resilience: Implications from genome-wide association studies and candidate genes of the stress response system in posttraumatic stress disorder and depression.

    Maul, Stephan / Giegling, Ina / Fabbri, Chiara / Corponi, Filippo / Serretti, Alessandro / Rujescu, Dan

    American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics

    2019  Volume 183, Issue 2, Page(s) 77–94

    Abstract: Resilience is the ability to cope with critical situations through the use of personal and socially mediated resources. Since a lack of resilience increases the risk of developing stress-related psychiatric disorders such as posttraumatic stress disorder ...

    Abstract Resilience is the ability to cope with critical situations through the use of personal and socially mediated resources. Since a lack of resilience increases the risk of developing stress-related psychiatric disorders such as posttraumatic stress disorder (PTSD) and major depressive disorder (MDD), a better understanding of the biological background is of great value to provide better prevention and treatment options. Resilience is undeniably influenced by genetic factors, but very little is known about the exact underlying mechanisms. A recently published genome-wide association study (GWAS) on resilience has identified three new susceptibility loci, DCLK2, KLHL36, and SLC15A5. Further interesting results can be found in association analyses of gene variants of the stress response system, which is closely related to resilience, and PTSD and MDD. Several promising genes, such as the COMT (catechol-O-methyltransferase) gene, the serotonin transporter gene (SLC6A4), and neuropeptide Y (NPY) suggest gene × environment interaction between genetic variants, childhood adversity, and the occurrence of PTSD and MDD, indicating an impact of these genes on resilience. GWAS on PTSD and MDD provide another approach to identifying new disease-associated loci and, although the functional significance for disease development for most of these risk genes is still unknown, they are potential candidates due to the overlap of stress-related psychiatric disorders and resilience. In the future, it will be important for genetic studies to focus more on resilience than on pathological phenotypes, to develop reasonable concepts for measuring resilience, and to establish international cooperations to generate sufficiently large samples.
    MeSH term(s) Adaptation, Psychological/physiology ; Catechol O-Methyltransferase/genetics ; Depression/genetics ; Depressive Disorder, Major/genetics ; Gene-Environment Interaction ; Genetic Predisposition to Disease ; Genome-Wide Association Study/methods ; Humans ; Neuropeptide Y/genetics ; Resilience, Psychological/classification ; Serotonin Plasma Membrane Transport Proteins/genetics ; Stress Disorders, Post-Traumatic/genetics ; Stress, Psychological/genetics ; Stress, Psychological/physiopathology
    Chemical Substances Neuropeptide Y ; SLC6A4 protein, human ; Serotonin Plasma Membrane Transport Proteins ; COMT protein, human (EC 2.1.1.6) ; Catechol O-Methyltransferase (EC 2.1.1.6)
    Language English
    Publishing date 2019-10-04
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2108616-3
    ISSN 1552-485X ; 1552-4841 ; 0148-7299
    ISSN (online) 1552-485X
    ISSN 1552-4841 ; 0148-7299
    DOI 10.1002/ajmg.b.32763
    Database MEDical Literature Analysis and Retrieval System OnLINE

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