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  1. Book ; Audio / Video ; Thesis: Der Einfluss traumatisierender Erlebnisse in der Kindheit auf Selbstwert, emotionales Erleben und Bindungseinstellungen bei selbstverletzenden Patienten

    Prieto Gil, Laura

    2010  

    Author's details vorgelegt von Laura Prieto Gil
    Language German
    Size 1 CD-ROM, 12 cm
    Publishing country Germany
    Document type Book ; Audio / Video ; Thesis
    Thesis / German Habilitation thesis Frankfurt (Main), Univ., Diss., 2012
    Accompanying material Beil. ([2] Bl.)
    HBZ-ID HT017245861
    Database Catalogue ZB MED Medicine, Health

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  2. Book ; Online ; Thesis: Der Einfluss traumatisierender Erlebnisse in der Kindheit auf Selbstwert, emotionales Erleben und Bindungseinstellungen bei selbstverletzenden Patienten

    Prieto Gil, Laura [Verfasser]

    2022  

    Author's details vorgelegt von Laura Prieto Gil
    Keywords Psychologie ; Psychology
    Subject code sg150
    Language German
    Publisher Leipzig ; Deutsche Nationalbibliothek
    Publishing place Frankfurt am Main
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

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  3. Article ; Online: Perils and possibilities of health exception laws: A narrative review.

    Shaw, Dorothy / Awoonor-Williams, Koku / Brauer, Annika / Gil, Laura / Morales, Juana Pérez / Chavkin, Wendy

    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics

    2024  Volume 164 Suppl 1, Page(s) 67–80

    Abstract: Forty-seven of the 203 countries with abortion laws detailed by the Center for Reproductive Rights have a health exception (HE) clause, inconsistent in both wording and implementation, even within countries. This narrative review sought to determine the ... ...

    Abstract Forty-seven of the 203 countries with abortion laws detailed by the Center for Reproductive Rights have a health exception (HE) clause, inconsistent in both wording and implementation, even within countries. This narrative review sought to determine the understanding and implementation of the legally permissible HE in different countries, or states, to provide clarification and guidance for strategies that will maximize permitted access to safe abortion within the law and avoid undue delays that harm the lives and health of women and their families. A multimethod approach was used. The literature search for countries with HE laws, including physical, mental, and social health, and exceptions for threat to life, rape, incest, and fetal anomaly, returned sparse results. The review of emblematic cases that had reached regional courts on the grounds of human rights violation for failure to obtain legal abortion under the country's HE clause included some examples qualifying on multiple grounds. We interviewed 15 physician advocates from 14 countries about use of the HE in their countries. Informants from Latin America interpreted the HE to refer to physical, psychological, and social health. HE laws are common but confusing, with significant opportunities to improve access through clarification and implementation. Where multiple grounds permit ending a pregnancy, the least onerous exception for the patient is the most ethical. Examples of progress in Colombia and Ghana demonstrate successful approaches to broader HE implementation.
    MeSH term(s) Pregnancy ; Female ; Humans ; Abortion, Induced ; Abortion, Legal ; Human Rights ; Latin America ; Rape
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Review ; Journal Article
    ZDB-ID 80149-5
    ISSN 1879-3479 ; 0020-7292
    ISSN (online) 1879-3479
    ISSN 0020-7292
    DOI 10.1002/ijgo.15337
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    In stock of ZB MED Cologne/Königswinter

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  4. Article ; Online: Urinary Electrophoretograms Performed by Capillary Electrophoresis: Comparison between Dogs and Cats.

    Gil, Laura / Wsol, Martyna / Fernández-Barredo, Salceda / Navarro, Paula Fátima

    Gels (Basel, Switzerland)

    2023  Volume 9, Issue 7

    Abstract: Electrophoresis of urine to evaluate different urinary proteins has been used in recent years in veterinary medicine, as it can be a useful laboratory tool in the early detection of kidney damage. However, urinary capillary electrophoresis (UCE) has not ... ...

    Abstract Electrophoresis of urine to evaluate different urinary proteins has been used in recent years in veterinary medicine, as it can be a useful laboratory tool in the early detection of kidney damage. However, urinary capillary electrophoresis (UCE) has not been reported in healthy cats. In healthy dogs, reference intervals have been established and can be compared with pathological samples as these provide an easily interpretable pattern. The electrophoretogram in this study is divided into five fractions (F1-F5) by serum (albumin; alpha
    Language English
    Publishing date 2023-07-04
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2813982-3
    ISSN 2310-2861 ; 2310-2861
    ISSN (online) 2310-2861
    ISSN 2310-2861
    DOI 10.3390/gels9070544
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  5. Article: Urinary phoretograms performed by capillary electrophoresis in dogs with chronic disease with or without

    Navarro, Paula Fátima / Fernández-Barredo, Salceda / Gil, Laura

    Frontiers in veterinary science

    2022  Volume 9, Page(s) 979669

    Abstract: Introduction: The study of early markers to detect kidney malfunction has increased in recent years since serum markers, such as creatinine increase when there is a 75% loss of renal mass. Urinary capillary electrophoresis (UCE) is an available ... ...

    Abstract Introduction: The study of early markers to detect kidney malfunction has increased in recent years since serum markers, such as creatinine increase when there is a 75% loss of renal mass. Urinary capillary electrophoresis (UCE) is an available laboratory technique that provides an easily interpretable electrophoretic pattern. This pattern in our study has been divided into five fractions as it is done in serum: fraction 1 migrating in the albumin zone, fraction 2 in the alpha
    Material and methods: In this study, UCE was performed in dogs with azotemia and proteinuria due to chronic kidney disease (CKD) not related to
    Results: Fraction 2 was statistically augmented in dogs with CKD (G
    Discussion: The results of the present study suggest that UCE is a promising non-invasive technique that might be used as a part of the diagnostic and follow-up in dogs with kidney disease due to different pathologies.
    Language English
    Publishing date 2022-11-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2834243-4
    ISSN 2297-1769
    ISSN 2297-1769
    DOI 10.3389/fvets.2022.979669
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  6. Article ; Online: Evaluation of Urine Proteins by Capillary Electrophoresis.

    Navarro, Paula F / Gil, Laura / Fernández-Barredo, Salceda

    Bio-protocol

    2022  Volume 12, Issue 15

    Abstract: Capillary electrophoresis (CE) is a laboratory method usually used to separate proteins in body fluids such as serum, cerebrospinal fluid, or urine. Separation of proteins in urine can have clinical applications for evaluating samples from healthy dogs ... ...

    Abstract Capillary electrophoresis (CE) is a laboratory method usually used to separate proteins in body fluids such as serum, cerebrospinal fluid, or urine. Separation of proteins in urine can have clinical applications for evaluating samples from healthy dogs and dogs with proteinuria in a qualitative way, which would not be possible with gel electrophoresis. Other advantages of CE over gel electrophoresis in serum include the reduced separation time (2 min vs. 20 min in a gel), reduction of waste harmful to humans and the environment, and ability to obtain a curve without the need for additional staining. This protocol is divided into four steps. Firstly, urine needs to be prepared prior to dialysis. Secondly, urine needs to undergo dialysis to eliminate compounds that could interfere with separation, and to concentrate the urine. The third step is CE using specific equipment. The last step is to separate the fractions of the phoretograms obtained in the previous step. This method is mostly an automatized process, easily reproducible, and that can be performed in any laboratory, as a part of the diagnostic or follow-up of patients with renal disease. Graphical abstract.
    Language English
    Publishing date 2022-08-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2833269-6
    ISSN 2331-8325 ; 2331-8325
    ISSN (online) 2331-8325
    ISSN 2331-8325
    DOI 10.21769/BioProtoc.4466
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Applying global lessons to protect abortion access in the United States.

    McGovern, Terry / Favier, Mary / Gil, Laura / Kitaba-Gaviglio, Bonsitu / Bencomo, Clarisa / Memaj, Ira / Garbers, Samantha / Maier, Malia

    BMJ (Clinical research ed.)

    2024  Volume 384, Page(s) e073833

    MeSH term(s) Pregnancy ; Female ; United States ; Humans ; Abortion, Induced ; Abortion, Legal ; Abortion, Spontaneous ; Health Services Accessibility
    Language English
    Publishing date 2024-01-03
    Publishing country England
    Document type Journal Article
    ZDB-ID 1362901-3
    ISSN 1756-1833 ; 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    ISSN (online) 1756-1833
    ISSN 0959-8154 ; 0959-8146 ; 0959-8138 ; 0959-535X ; 1759-2151
    DOI 10.1136/bmj-2022-073833
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  8. Article ; Online: Print and digital reading habits and comprehension in children with and without special education needs.

    Vargas, Cristina / Altamura, Lidia / Blanco-Gandía, Mari Carmen / Gil, Laura / Mañá, Amelia / Montagud, Sandra / Salmerón, Ladislao

    Research in developmental disabilities

    2024  Volume 146, Page(s) 104675

    Abstract: Background: Text comprehension is a major obstacle for many Primary school students with special education needs (SEN). Reading episodes bring students opportunities to be exposed to new vocabulary and knowledge, potentially boosting their development ... ...

    Abstract Background: Text comprehension is a major obstacle for many Primary school students with special education needs (SEN). Reading episodes bring students opportunities to be exposed to new vocabulary and knowledge, potentially boosting their development of text comprehension skills.
    Aims: Our study seeks to understand how reading frequency (leisure and academic) and reading medium (print and digital) contribute to the development of text comprehension during Primary school in students with and without SEN.
    Methods and procedures: We tested 2289 Spanish students from fourth to sixth grade, from which 212 had an official decision of SEN. Students self-reported their reading frequency (as a measure of their reading habits) and completed a standardized text comprehension test. We employed multiple regression models with a robust maximum likelihood estimator to test associations between reading frequency and comprehension.
    Outcomes and results: Students' comprehension was positively associated with their leisure print reading habits, and negatively associated with their frequency of academic digital reading. Those associations were independent of SEN status.
    Conclusions and implications: Results highlight the importance of promoting leisure reading in print to all students, regardless of SEN status. In addition, caution is advised when encouraging Primary school children to use digital texts when the emphasis is on comprehending texts for acquiring knowledge.
    MeSH term(s) Child ; Humans ; Comprehension ; Reading ; Students ; Habits ; Education, Special
    Language English
    Publishing date 2024-01-23
    Publishing country United States
    Document type Journal Article
    ZDB-ID 639175-8
    ISSN 1873-3379 ; 0891-4222
    ISSN (online) 1873-3379
    ISSN 0891-4222
    DOI 10.1016/j.ridd.2024.104675
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    Zs.B 2592: Show issues Location:
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  9. Article ; Online: Phospho-Tau and Chromatin Landscapes in Early and Late Alzheimer's Disease.

    Gil, Laura / Niño, Sandra A / Guerrero, Carmen / Jiménez-Capdeville, María E

    International journal of molecular sciences

    2021  Volume 22, Issue 19

    Abstract: Cellular identity is determined through complex patterns of gene expression. Chromatin, the dynamic structure containing genetic information, is regulated through epigenetic modulators, mainly by the histone code. One of the main challenges for the cell ... ...

    Abstract Cellular identity is determined through complex patterns of gene expression. Chromatin, the dynamic structure containing genetic information, is regulated through epigenetic modulators, mainly by the histone code. One of the main challenges for the cell is maintaining functionality and identity, despite the accumulation of DNA damage throughout the aging process. Replicative cells can remain in a senescent state or develop a malign cancer phenotype. In contrast, post-mitotic cells such as pyramidal neurons maintain extraordinary functionality despite advanced age, but they lose their identity. This review focuses on tau, a protein that protects DNA, organizes chromatin, and plays a crucial role in genomic stability. In contrast, tau cytosolic aggregates are considered hallmarks of Alzheimer´s disease (AD) and other neurodegenerative disorders called tauopathies. Here, we explain AD as a phenomenon of chromatin dysregulation directly involving the epigenetic histone code and a progressive destabilization of the tau-chromatin interaction, leading to the consequent dysregulation of gene expression. Although this destabilization could be lethal for post-mitotic neurons, tau protein mediates profound cellular transformations that allow for their temporal survival.
    MeSH term(s) Alzheimer Disease/etiology ; Alzheimer Disease/genetics ; Alzheimer Disease/metabolism ; Chromatin/genetics ; Chromatin/metabolism ; DNA/chemistry ; DNA/genetics ; DNA/metabolism ; DNA Damage ; Epigenesis, Genetic ; Genomic Instability ; Histone Code ; Humans ; Nucleosomes/metabolism ; Phosphorylation ; Time Factors ; tau Proteins/chemistry ; tau Proteins/genetics ; tau Proteins/metabolism
    Chemical Substances Chromatin ; MAPT protein, human ; Nucleosomes ; tau Proteins ; DNA (9007-49-2)
    Language English
    Publishing date 2021-09-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms221910283
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  10. Article ; Online: Reference intervals for electrophoretograms obtained by capillary electrophoresis of dialyzed urine from healthy dogs.

    Navarro, Paula F / Gil, Laura / Martín, Germán / Fernández-Barredo, Salceda

    Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc

    2021  Volume 33, Issue 4, Page(s) 632–639

    Abstract: Electrophoresis of urine to evaluate protein fractions in dogs with proteinuria to differentiate glomerular from tubular damage has increased in recent years; however, capillary electrophoresis (CE) of urine has not been reported in a study of > 40 ... ...

    Abstract Electrophoresis of urine to evaluate protein fractions in dogs with proteinuria to differentiate glomerular from tubular damage has increased in recent years; however, capillary electrophoresis (CE) of urine has not been reported in a study of > 40 healthy animals, to our knowledge. We aimed to establish reference intervals (RIs) for the urine protein fractions obtained by CE of urine from healthy dogs. We obtained urine samples from 123 clinically healthy dogs of both sexes between December 2016 and April 2019; urine was frozen until CE was performed. The electrophoretic patterns obtained were divided into 5 protein fractions, and RIs were established in percentages and absolute values using nonparametric methods. RIs were obtained for the fractions (F) as follows: 5.5 to 56.2% for F1, 3.2 to 16.5% for F2, 3.5 to 16.2% for F3, 17.8 to 69.8% for F4, and 5.1 to 23.9% for F5. These RIs obtained by CE might be useful clinically as a basis for comparison with pathologic samples. Age was a statistically significant factor for F2 (
    MeSH term(s) Animals ; Dogs/urine ; Electrophoresis, Capillary/standards ; Electrophoresis, Capillary/veterinary ; Female ; Male ; Reference Values ; Renal Dialysis/standards ; Renal Dialysis/veterinary
    Language English
    Publishing date 2021-06-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 287603-6
    ISSN 1943-4936 ; 1040-6387
    ISSN (online) 1943-4936
    ISSN 1040-6387
    DOI 10.1177/10406387211020117
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