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  1. Article ; Online: Innovative Surgical Workshops Targeting Undergraduate, Premedical, and Medical Students.

    Gilman, Alex / Kraszpulska, Barbara

    Medical science educator

    2022  Volume 32, Issue 4, Page(s) 771–772

    Abstract: Knowledge of anatomy and comprehensive body navigation is essential for operating specialties and the practice of medicine. Focused surgical anatomical training exposure at undergraduate and medical student levels aims to increase functional ... ...

    Abstract Knowledge of anatomy and comprehensive body navigation is essential for operating specialties and the practice of medicine. Focused surgical anatomical training exposure at undergraduate and medical student levels aims to increase functional understanding of medical anatomy and draws an early exposure to surgical career fields while enhancing surgical confidence.
    Language English
    Publishing date 2022-07-16
    Publishing country United States
    Document type Journal Article
    ISSN 2156-8650
    ISSN (online) 2156-8650
    DOI 10.1007/s40670-022-01590-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Efficacy of Antidopaminergic Pharmacotherapy in Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections (PANDAS): A Case Report.

    Hefelfinger, Donald / Kaufman, Hannah / Gilman, Alex / Gebhart, Rick

    Cureus

    2023  Volume 15, Issue 8, Page(s) e44164

    Abstract: PANDAS, or pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections, is a neuropsychiatric disease seen in children that presents with prevailing symptoms of obsessive-compulsive disorder (OCD), tic disorder, or both. ... ...

    Abstract PANDAS, or pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections, is a neuropsychiatric disease seen in children that presents with prevailing symptoms of obsessive-compulsive disorder (OCD), tic disorder, or both. These symptoms appear suddenly following a streptococcal infection, such as strep throat or scarlet fever. The antibodies formed to eradicate the streptococcal infection have been shown to alter central dopamine signaling. In spite of being acknowledged in the medical community for the last two to three decades, PANDAS is a disorder that goes unnoticed by many healthcare professionals. Unfortunately, even with correct diagnosis and utilization of commonly prescribed pharmacotherapy and psychotherapy, medical management can often be ineffective at treating the neuropsychiatric symptoms. Here, we describe a case of a 15-year-old male who presented to the primary care office with complaints of episodic behavioral changes that would occur multiple times daily. The general symptoms were centered around body dysmorphia where the patient became obsessed with fixed portions of food and became highly focused on only specific food types. The symptoms would exacerbate and progress with a dire need to burn calories, leading the patient to damage carpeted areas in the home due to regular and fanatical pacing. The patient underwent trials with serotonergic pharmacotherapy with little to no relief of the psychiatric symptoms. After discussion with his primary care physician, the patient underwent trial management with antidopaminergic therapy that resulted in significant neurological and psychiatric improvement. The use of antidopaminergic pharmacotherapy to target the induction of D1 and D2 dopamine receptors was efficacious in this patient; however, it warrants additional research with a larger sample to determine its effectiveness in the treatment of this psychiatric condition.
    Language English
    Publishing date 2023-08-26
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.44164
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Incidental Scleral Icterus in an Adolescent Male With Nausea: Clinical Diagnosis of Gilbert Syndrome in the Pediatric Outpatient Setting.

    Gilman, Alex / Hatcher, Vishaka R / Hefelfinger, Donald

    Cureus

    2023  Volume 15, Issue 8, Page(s) e43298

    Abstract: Gilbert syndrome is a condition of non-hemolytic hyperbilirubinemia without further sequelae or primary laboratory abnormalities. Gilbert syndrome represents the most common hereditary disorder of bilirubin metabolism and is frequently identified as the ... ...

    Abstract Gilbert syndrome is a condition of non-hemolytic hyperbilirubinemia without further sequelae or primary laboratory abnormalities. Gilbert syndrome represents the most common hereditary disorder of bilirubin metabolism and is frequently identified as the etiology of familial jaundice in clinical medicine. This disorder typically manifests as mild unconjugated hyperbilirubinemia of benign nature. The diagnosis of Gilbert syndrome entails clinical assessment corroborated by the laboratory findings above in the absence of hemolysis or other organic liver diseases. We report a case of a 17-year-old boy who presented to a pediatric clinic with dyspepsia for the management of digestive symptoms, with clinical findings of mild scleral icterus and laboratory findings of isolated indirect hyperbilirubinemia. This case is unique in its subtlety of presentation. It highlights to trainees and experienced physicians the importance of the physical examination and targeted laboratory workup to arrive at the diagnosis of Gilbert syndrome.
    Language English
    Publishing date 2023-08-10
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.43298
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: The pharmacology of drugs used in allergic conditions.

    GILMAN, A

    The Journal of allergy

    2008  Volume 19, Issue 5, Page(s) 281–287

    MeSH term(s) Anaphylaxis ; Drug Hypersensitivity ; Humans ; Hypersensitivity ; Immune System Diseases ; Pharmaceutical Preparations
    Chemical Substances Pharmaceutical Preparations
    Language English
    Publishing date 2008-09-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 121010-5
    ISSN 0021-8707
    ISSN 0021-8707
    DOI 10.1016/0021-8707(48)90107-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  5. Article: Auditory and Visual Hallucinations Associated With Nitrofurantoin Use in an Inpatient Setting: A Case Report.

    Gilman, Alex / Von Der Vellen, Daniel / Stuart, Ryan / Harvey, Russell S

    Cureus

    2023  Volume 15, Issue 3, Page(s) e36094

    Abstract: Nitrofurantoin has been utilized for the prevention and treatment of urinary tract infections (UTIs) since the 1950s, and it has been prescribed with increasing frequency since being recommended as a first-line therapy. The adverse neurological and ... ...

    Abstract Nitrofurantoin has been utilized for the prevention and treatment of urinary tract infections (UTIs) since the 1950s, and it has been prescribed with increasing frequency since being recommended as a first-line therapy. The adverse neurological and psychiatric effects of antibiotic medications have been well-established. There is evidence to suggest a direct association between acute psychosis and antibiotic exposures. Nitrofurantoin-induced adverse effects have been reported recurrently; however, to the best of our knowledge, a combination of auditory and visual hallucinations with normal baseline mentation and cognition in an immunocompetent geriatric patient, without previously reported hallucinations, have not been reported in the literature so far. We present a case of an 86-year-old Caucasian female who was admitted with audio and visual hallucinations on the fifth day of starting nitrofurantoin therapy for UTI. During her stay, after ruling out all other probable etiologies, it was determined that the likely pathogenesis of the patient's neuropsychiatric effects was the use of nitrofurantoin.
    Language English
    Publishing date 2023-03-13
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.36094
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: An uncommon presentation of a multifocal spinal osseous sarcoidosis: A case report on the diagnosis and exclusion with literature review.

    Gilman, Alex / Burke, Amanda / Nolan, Kailey / Beckmeyer, Lauren / Hefelfinger, Donald / Peters, Austin / Nelson, Steve

    Radiology case reports

    2023  Volume 19, Issue 2, Page(s) 711–715

    Abstract: Sarcoidosis is a granulomatous disease of indeterminate etiology. Women are more commonly affected than men at nearly twice the incidence with black women most commonly afflicted in the United States. Osseous spinal sarcoidosis (SS) is thought to be ... ...

    Abstract Sarcoidosis is a granulomatous disease of indeterminate etiology. Women are more commonly affected than men at nearly twice the incidence with black women most commonly afflicted in the United States. Osseous spinal sarcoidosis (SS) is thought to be uncommon. Such lesions are often mistaken for metastatic disease, multiple myeloma, or disseminated fungal/granulomatous infection complicating the diagnosis, clinical course, and treatment. Patients presenting with clinical and imaging features of sarcoidosis may have normal serum laboratory values further complicating diagnosis. We present the case of a 61-year-old African American female with a diagnosis of osseous spinal sarcoidosis and normal calcium and ACE levels. Her initial presentation began with an incidentally discovered pulmonary nodule and was subsequently discovered to have multiple enlarging pulmonary nodules and widespread sclerotic lesions throughout her spine. This imaging presentation occurred before development of hilar adenopathy and cutaneous manifestations of sarcoidosis. Here, we describe her clinical course, exclusion of metastatic disease, and other confounders to arrive at the correct diagnosis.
    Language English
    Publishing date 2023-11-29
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2023.11.021
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Mechanistic Elucidations of Highly Dispersed Metalloporphyrin Metal-Organic Framework Catalysts for CO

    Smith, Michael R / Martin, Clare B / Arumuganainar, Sonia / Gilman, Ari / Koel, Bruce E / Sarazen, Michele L

    Angewandte Chemie (International ed. in English)

    2023  Volume 62, Issue 8, Page(s) e202218208

    Abstract: Immobilization of porphyrin complexes into crystalline metal-organic frameworks (MOFs) enables high exposure of porphyrin active sites for ... ...

    Abstract Immobilization of porphyrin complexes into crystalline metal-organic frameworks (MOFs) enables high exposure of porphyrin active sites for CO
    Language English
    Publishing date 2023-01-18
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202218208
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Examining the viability of dorsal fin pigmentation for individual identification of poorly-marked delphinids.

    Pawley, M D M / Hupman, K E / Stockin, K A / Gilman, A

    Scientific reports

    2018  Volume 8, Issue 1, Page(s) 12593

    Abstract: Dolphin photo-identification has traditionally relied only on distinctive markings on the dorsal fin-this is problematic for delphinids whose populations exhibit a low mark ratio. We used common dolphins (genus Delphinus) as a model species to assess the ...

    Abstract Dolphin photo-identification has traditionally relied only on distinctive markings on the dorsal fin-this is problematic for delphinids whose populations exhibit a low mark ratio. We used common dolphins (genus Delphinus) as a model species to assess the viability of using pigmentation for photo-identification. Using a photo-identification catalogue of 169 adult individuals collected between 2002 and 2013, we extracted features that quantified pigmentation in a manner that was robust to lighting artefacts and dorsal fin orientation. We determined the proportion of individuals which exhibited pigmentation and examined temporal stability by (i) visually examining individuals and (ii) testing for seriation. We found 88-91% of images could be manually matched to the correct individual in the catalogue based on pigmentation patterns alone. A linear discriminant analysis classifier correctly identified the correct individual 77% of the time. We found 95% common dolphins exhibited distinctive pigmentation-all of which were temporarily stable. Our work challenges the current thinking that pigmentation is an unreliable feature for delphinid photo-identification and suggests that this feature could be applied to common dolphins and other poorly-marked delphinids.
    MeSH term(s) Animal Fins/anatomy & histology ; Animal Identification Systems/methods ; Animals ; Dolphins/anatomy & histology ; Dolphins/classification ; Pigmentation ; Skin Pigmentation/physiology
    Language English
    Publishing date 2018-08-22
    Publishing country England
    Document type Journal Article
    ZDB-ID 2615211-3
    ISSN 2045-2322 ; 2045-2322
    ISSN (online) 2045-2322
    ISSN 2045-2322
    DOI 10.1038/s41598-018-30842-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Book ; Online: Land-use and Prehistory in South-East Spain

    Gilman, A / Thornes, J. B

    (Routledge Library Editions: Archaeology)

    2014  

    Abstract: Based on a major research programme, and originally published in 1985, this book looked to provide an economic foundation for reinterpreting the Neolithic-Bronze Age sequence of South-east Spain in terms of emergent social complexity. The cultural ... ...

    Series title Routledge Library Editions: Archaeology
    Abstract Based on a major research programme, and originally published in 1985, this book looked to provide an economic foundation for reinterpreting the Neolithic-Bronze Age sequence of South-east Spain in terms of emergent social complexity. The cultural evolution of the area had already been considered in terms of influence from the eastern Mediterranean but this book uses site catchment analysis to give an economic baseline for all thirty-five of the better-known prehistoric settlements of the region.Site catchment analysis assumes that people minimised transport costs in production and that ancien
    Language English
    Size Online-Ressource (232 p)
    Publisher Taylor and Francis
    Publishing place Hoboken
    Document type Book ; Online
    Note Description based upon print version of record
    ISBN 9781138813502 ; 1138813508
    Database Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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  10. Article ; Online: Newsmaker interview. Texas transplant Alfred Gilman guides $3 billion cancer project. Interview by Jocelyn Kaiser.

    Gilman, Alfred

    Science (New York, N.Y.)

    2009  Volume 324, Issue 5929, Page(s) 868

    MeSH term(s) Academies and Institutes/economics ; Academies and Institutes/organization & administration ; Biomedical Research/economics ; Humans ; Neoplasms/prevention & control ; Neoplasms/therapy ; Peer Review, Research ; Research Support as Topic ; Texas
    Language English
    Publishing date 2009-05-15
    Publishing country United States
    Document type Interview ; News
    ZDB-ID 128410-1
    ISSN 1095-9203 ; 0036-8075
    ISSN (online) 1095-9203
    ISSN 0036-8075
    DOI 10.1126/science.324_868
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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