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  1. Article ; Online: Short-Term and Long-Term Predictions: Is the Green Crab Carcinus maenas a Threat to Antarctica and Southern South America under a Climate-Change Scenario?

    Vera Escalona, Iván / Gimenez, Lucas H. / Brante, Antonio

    Diversity. 2023 May 06, v. 15, no. 5

    2023  

    Abstract: Non-native species can have profound implications on the survival of native ones. This is especially true for some invasive crabs, such as the green crab Carcinus maenas, a native species to the Northern Hemisphere that has been introduced into southern ... ...

    Abstract Non-native species can have profound implications on the survival of native ones. This is especially true for some invasive crabs, such as the green crab Carcinus maenas, a native species to the Northern Hemisphere that has been introduced into southern Argentina, from where it could expand through Argentina, Chile, and the Antarctic Peninsula. Hence, there is interest in forecasting changes in C. maenas habitat suitability through time to predict if potential future invasions might occur. Here, by using a Species Distribution Model (SDM) approach, we estimated the habitat suitability for C. maenas along southern South America and the Antarctic Peninsula under two future climate-change scenarios. Our results reveal that under current conditions, habitat suitability for C. maenas along the Antarctic Peninsula is null and very restricted in Argentina and Chile. Habitat suitability along the Antarctic Peninsula remained null in the short-term (30 years) and long-term future (80 years), despite the climate-change scenario considered. Surprisingly, when considering future conditions, habitat suitability along the coast of Argentina and Chile decreased and became nil for some currently occupied locations. Thus, the SDM results suggest that climate change could have a negative effect on the habitat suitability of C. maenas leading to potential local extinctions.
    Keywords Carcinus maenas ; climate change ; coasts ; crabs ; geographical distribution ; habitats ; indigenous species ; introduced species ; models ; Antarctic region ; Antarctica ; Argentina ; Chile
    Language English
    Dates of publication 2023-0506
    Publishing place Multidisciplinary Digital Publishing Institute
    Document type Article ; Online
    ZDB-ID 2518137-3
    ISSN 1424-2818
    ISSN 1424-2818
    DOI 10.3390/d15050632
    Database NAL-Catalogue (AGRICOLA)

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  2. Article ; Online: Gamification as a Tool for Promoting Physical Exercise and Healthy Eating Habits in Healthcare Worker Women: Effects on Cardiometabolic Health and Physical Fitness at Workplace.

    Gimenez, Lucas B / Teixeira do Amaral, Vanessa / Locato, Gabriel / Marçal, Isabela R / Ferron, Artur J T / Ciolac, Emmanuel G

    American journal of health promotion : AJHP

    2024  , Page(s) 8901171241234664

    Abstract: Purpose: To evaluate the effectiveness of gamified versus nongamified health promotion interventions on cardiometabolic health and fitness parameters in healthcare worker women.: Design: Randomized parallel group trial.: Setting: A public ... ...

    Abstract Purpose: To evaluate the effectiveness of gamified versus nongamified health promotion interventions on cardiometabolic health and fitness parameters in healthcare worker women.
    Design: Randomized parallel group trial.
    Setting: A public outpatient health center in Brazil.
    Subjects: Women employees (included: n = 29; lost to follow-up: n = 1; analyzed: n = 28).
    Interventions: 8 weeks of gamified (n = 15) or nongamified (n = 13) interventions, consisting of health lectures, nutritional counseling, and supervised exercise training. The gamified group was divided into teams that received points based on completion of health goals/tasks.
    Measures: Anthropometric, cardiometabolic and physical fitness parameters.
    Analysis: Two-way ANOVA with repeated measures (group vs. time), and Bonferroni
    Results: Body mass (-1.5 ± 1.5 kg), waist circumference (-1.6 ± 3.0 cm), HbA1C (-.2 ± .3%), triglycerides (-21.5 ± 48.2 mg/dl), systolic (-11.1 ± 7.9 mmHg) and diastolic (-7.1 ± 5.8 mmHg) blood pressure, as well as sit and reach (3.9 ± 3.0 cm) and six-minute walking (56 ± 37 m) performance improved (
    Conclusion: The gamified intervention was more effective than the nongamified intervention for improving cardiometabolic and physical fitness parameters, suggesting that gamification may be an effective tool for promoting health in healthcare worker women.
    Language English
    Publishing date 2024-02-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 645160-3
    ISSN 2168-6602 ; 0890-1171
    ISSN (online) 2168-6602
    ISSN 0890-1171
    DOI 10.1177/08901171241234664
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: The potential of Glycymeris longior (Mollusca, Bivalvia) as a multi-decadal sclerochronological archive for the Argentine Sea (Southern Hemisphere)

    Gimenez, Lucas H / Doldan, María del Socorro / Morsan, Enrique M / Zaidman, Paula C

    Marine environmental research. 2020 Mar., v. 155

    2020  

    Abstract: In the absence of instrumental records, shell growth increments of bivalves are used to build continuous multi-decadal time series of growth and to estimate environmental variability. While there is interest in such chronologies in the Northern ... ...

    Abstract In the absence of instrumental records, shell growth increments of bivalves are used to build continuous multi-decadal time series of growth and to estimate environmental variability. While there is interest in such chronologies in the Northern Hemisphere, there is a lack of multi-decadal datasets of growth for marine species from the Southern Hemisphere. We assessed the potential of the clam Glycymeris longior as an environmental proxy archive for the mid-latitudes of the South Atlantic Ocean, by applying sclerochronological techniques on the shells of individuals from a coastal area in Northern Patagonia, Argentina. Growth of G. longior showed a synchronous pattern, and shells were cross dated. We demonstrated that G. longior shells can be used to generate a robust multi-decadal chronology. The chronology spanned for a period of 22 years, from 1990 to 2011. This chronology has the potential to be extended, given that the maximum longevity of the analysed shells was 69 years. Significant positive correlations were found between the chronology and sea surface temperature and the Southern Annular Mode index. The sclerochronological approach performed in this study is a first step toward a long-term understanding of the links between climate and growth patterns of bivalves in temperate regions of SW Atlantic Ocean, under a long-term perspective.
    Keywords Bivalvia ; clams ; coasts ; data collection ; latitude ; longevity ; surface water temperature ; temperate zones ; time series analysis ; Argentina ; Atlantic Ocean
    Language English
    Dates of publication 2020-03
    Publishing place Elsevier Ltd
    Document type Article
    ZDB-ID 1502505-6
    ISSN 1879-0291 ; 0141-1136
    ISSN (online) 1879-0291
    ISSN 0141-1136
    DOI 10.1016/j.marenvres.2020.104879
    Database NAL-Catalogue (AGRICOLA)

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  4. Article ; Online: The potential of Glycymeris longior (Mollusca, Bivalvia) as a multi-decadal sclerochronological archive for the Argentine Sea (Southern Hemisphere).

    Gimenez, Lucas H / Doldan, María Del Socorro / Zaidman, Paula C / Morsan, Enrique M

    Marine environmental research

    2020  Volume 155, Page(s) 104879

    Abstract: In the absence of instrumental records, shell growth increments of bivalves are used to build continuous multi-decadal time series of growth and to estimate environmental variability. While there is interest in such chronologies in the Northern ... ...

    Abstract In the absence of instrumental records, shell growth increments of bivalves are used to build continuous multi-decadal time series of growth and to estimate environmental variability. While there is interest in such chronologies in the Northern Hemisphere, there is a lack of multi-decadal datasets of growth for marine species from the Southern Hemisphere. We assessed the potential of the clam Glycymeris longior as an environmental proxy archive for the mid-latitudes of the South Atlantic Ocean, by applying sclerochronological techniques on the shells of individuals from a coastal area in Northern Patagonia, Argentina. Growth of G. longior showed a synchronous pattern, and shells were cross dated. We demonstrated that G. longior shells can be used to generate a robust multi-decadal chronology. The chronology spanned for a period of 22 years, from 1990 to 2011. This chronology has the potential to be extended, given that the maximum longevity of the analysed shells was 69 years. Significant positive correlations were found between the chronology and sea surface temperature and the Southern Annular Mode index. The sclerochronological approach performed in this study is a first step toward a long-term understanding of the links between climate and growth patterns of bivalves in temperate regions of SW Atlantic Ocean, under a long-term perspective.
    MeSH term(s) Animals ; Argentina ; Atlantic Ocean ; Bivalvia/growth & development ; Climate ; Environmental Monitoring
    Language English
    Publishing date 2020-01-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 1502505-6
    ISSN 1879-0291 ; 0141-1136
    ISSN (online) 1879-0291
    ISSN 0141-1136
    DOI 10.1016/j.marenvres.2020.104879
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Paternal age and risk for selected birth defects in a large South American sample.

    Gili, Juan A / Rittler, Monica / Heisecke, Silvina / Campaña, Hebe / Giménez, Lucas / Santos, María Rita / Ratowiecki, Julia / Cosentino, Viviana / López Camelo, Jorge / Poletta, Fernando A

    Birth defects research

    2023  Volume 115, Issue 19, Page(s) 1866–1875

    Abstract: Background: The relationship between maternal age (MA) and birth defects (BD) has been extensively studied while much less research, mostly with discordant results, has focused on the risk of paternal age (PA) for BD. Furthermore, no consensus has been ... ...

    Abstract Background: The relationship between maternal age (MA) and birth defects (BD) has been extensively studied while much less research, mostly with discordant results, has focused on the risk of paternal age (PA) for BD. Furthermore, no consensus has been reached on the best way to control the association of PA with MA.
    Objectives: The aim of the study was to evaluate the risk of PA increase, at 1-year intervals, for selected BD, especially controlling for the confounding effect of MA.
    Methods: The sample comprised of 27,944 liveborns presenting 1 of 18 selected isolated BD. Conditional logistic regressions were applied to evaluate the risk of advanced PA and its yearly increase, adjusting by MA and other variables.
    Results: Of the 18 analyzed BD, only the risk for preaxial polydactyly (PreP) showed a significant association with increasing PA, while advanced MA was of low risk. For esophageal and anal atresia, associations with both PA and MA increases were observed.
    Conclusions: Results support the hypothesis of advanced PA as a risk factor for PreP and helps clarify the so far unexplained nonrandom association between this defect and Down syndrome.
    MeSH term(s) Humans ; Male ; Anus, Imperforate/epidemiology ; Paternal Age ; Risk Factors ; South America/epidemiology ; Polydactyly/epidemiology
    Language English
    Publishing date 2023-09-20
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2104792-3
    ISSN 2472-1727
    ISSN (online) 2472-1727
    DOI 10.1002/bdr2.2252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Gene-environment interactions and preterm birth predictors: A Bayesian network approach.

    Elias, Dario E / Santos, Maria R / Campaña, Hebe / Poletta, Fernando A / Heisecke, Silvina L / Gili, Juan A / Ratowiecki, Julia / Cosentino, Viviana R / Uranga, Rocio / Málaga, Diana Rojas / Oliveira Netto, Alice Brinckmann / Brusius-Facchin, Ana Carolina / Saleme, César / Rittler, Mónica / Krupitzki, Hugo B / Camelo, Jorge S Lopez / Gimenez, Lucas G

    Genetics and molecular biology

    2024  Volume 46, Issue 4, Page(s) e20230090

    Abstract: Preterm birth (PTB) is the main condition related to perinatal morbimortality worldwide. The aim of this study was to identify gene-environment interactions associated with spontaneous PTB or its predictors. We carried out a retrospective case-control ... ...

    Abstract Preterm birth (PTB) is the main condition related to perinatal morbimortality worldwide. The aim of this study was to identify gene-environment interactions associated with spontaneous PTB or its predictors. We carried out a retrospective case-control study including parental sociodemographic and obstetric data as well as newborn genetic variants of 69 preterm and 61 at term newborns born at a maternity hospital from Tucumán, Argentina, between 2005 and 2010. A data-driven Bayesian network including the main PTB predictors was created where we identified gene-environment interactions. We used logistic regressions to calculate the odds ratios and confidence intervals of the interactions. From the main PTB predictors (nine exposures and six genetic variants) we identified an interaction between low neighbourhood socioeconomic status and rs2074351 (PON1, genotype GG) variant that was associated with an increased risk of toxoplasmosis (odds ratio 12.51, confidence interval 95%: 1.71 - 91.36). The results of this exploratory study suggest that structural social disparities could influence the PTB risk by increasing the frequency of exposures that potentiate the risk associated with individual characteristics such as genetic traits. Future studies with larger sample sizes are necessary to confirm these findings.
    Language English
    Publishing date 2024-01-19
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 1445712-x
    ISSN 1678-4685 ; 1415-4757
    ISSN (online) 1678-4685
    ISSN 1415-4757
    DOI 10.1590/1678-4685-GMB-2023-0090
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Genetic susceptibility for retinopathy of prematurity and its associated comorbidities.

    Gimenez, Lucas G / Gili, Juan A / Elias, Darío E / Sagula, Rubén / Comas, Belén / Santos, María R / Campaña, Hebe / Poletta, Fernando A / Heisecke, Silvina L / Ratowiecki, Julia / Cosentino, Viviana R / Uranga, Rocío / Saleme, César / Negri, Mercedes / Rittler, Mónica / Zapata Barrios, Jorge / Krupitzki, Hugo B / López Camelo, Jorge S

    Pediatric research

    2024  

    Abstract: Background: Retinopathy of prematurity (ROP) is one of the leading cause of child blindness. Preterm newborns of very low gestational age (GA) and very low birth weight are at the greatest risk. Our objective was to evaluate the role of genetic variants ...

    Abstract Background: Retinopathy of prematurity (ROP) is one of the leading cause of child blindness. Preterm newborns of very low gestational age (GA) and very low birth weight are at the greatest risk. Our objective was to evaluate the role of genetic variants associated with ROP risk and its comorbidities in an Argentinian sample of premature infants.
    Methods: A sample of 437 preterm infants <33 weeks GA, born at a maternity hospital in Tucumán, Argentina, 2005-2010, was analyzed. Environmental factors, perinatal outcomes, and fourteen single nucleotide polymorphisms associated with ROP were evaluated, comparing ROP with non-ROP newborns. A lasso logistic regression was performed to select variables; then, a conditional logistic regression was used to identify ROP maternal and perinatal risk factors adjusting by maternal and gestational ages, respectively.
    Results: ROP maternal risk factors were alcohol intake, periodontal infections, and severe stress. Respiratory distress, sepsis, and intracranial hemorrhage were the ROP perinatal risk factors. Markers rs186085 of EPAS1 and rs427832 of AGTR1 were significantly associated with ROP newborns.
    Conclusion: We identified three maternal and three perinatal risk factors associated with ROP. Genes EPAS1 and AGTR1, involved in angiogenesis and vascularization, were identified to be of risk for ROP.
    Impact: Genetic and environmental risk factors associated with ROP and its comorbidities are evaluated in a Latin American population. Genes EPAS1 and AGTR1, involved in angiogenesis and vascularization, were identified to be of risk for ROP. Three maternal and three perinatal risk factors associated with ROP were also identified. A matrix of significant relationships among genetic markers and comorbidities is presented. Reported data may help develop more effective preventive measures for ROP in the Latin American region.
    Language English
    Publishing date 2024-02-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 4411-8
    ISSN 1530-0447 ; 0031-3998
    ISSN (online) 1530-0447
    ISSN 0031-3998
    DOI 10.1038/s41390-024-03068-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The impact of unemployment cycles on child and maternal health in Argentina.

    Wehby, George L / Gimenez, Lucas G / López-Camelo, Jorge S

    International journal of public health

    2017  Volume 62, Issue 2, Page(s) 197–207

    Abstract: Objectives: The purpose of this study is to examine the effects of economic cycles in Argentina on infant and maternal health between 1994 and 2006, a period that spans the major economic crisis in 1999-2002.: Methods: We evaluate the effects of ... ...

    Abstract Objectives: The purpose of this study is to examine the effects of economic cycles in Argentina on infant and maternal health between 1994 and 2006, a period that spans the major economic crisis in 1999-2002.
    Methods: We evaluate the effects of province-level unemployment rates on several infant health outcomes, including birth weight, gestational age, fetal growth rate, and hospital discharge status after birth in a sample of 15,000 infants born in 13 provinces. Maternal health and healthcare outcomes include acute and chronic illnesses, infectious diseases, and use of prenatal visits and technology. Regression models control for hospital and year fixed effects and province-specific time trends.
    Results: Unemployment rise reduces fetal growth rate particularly among high educated parents. Also, maternal poverty-related infectious diseases increase, although reporting of acute illnesses declines (an effect more pronounced among low educated parents). There is also some evidence for reduced access to prenatal care and technology among less educated parents with higher unemployment.
    Conclusions: Unemployment rise in Argentina has adversely affected certain infant and maternal health outcomes, but several measures show no evidence of significant change.
    MeSH term(s) Adolescent ; Adult ; Argentina ; Economic Recession ; Female ; Humans ; Infant ; Infant Health/statistics & numerical data ; Infant, Newborn ; Maternal Health/statistics & numerical data ; Pregnancy ; Unemployment/statistics & numerical data ; Young Adult
    Language English
    Publishing date 2017-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2274130-6
    ISSN 1661-8564 ; 1661-8556
    ISSN (online) 1661-8564
    ISSN 1661-8556
    DOI 10.1007/s00038-016-0857-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Diseases during pregnancy in a large unselected South American sample.

    Santos, María Rita / Campaña, Hebe / Heisecke, Silvina / Ratowiecki, Julia / Elías, Darío / Giménez, Lucas / Poletta, Fernando Adrián / Gili, Juan / Uranga, Rocío / Cosentino, Viviana / Krupitzki, Hugo / Rittler, Mónica / Camelo, Jorge López

    Revista brasileira de epidemiologia = Brazilian journal of epidemiology

    2022  Volume 25, Page(s) e220043

    Abstract: Objective: Our aim was to describe the prevalence of diseases during pregnancy and the association between fetal exposure to the most frequent maternal diseases and the risk of preterm (PTB) and/or small for gestational age (SGA) newborns in an ... ...

    Abstract Objective: Our aim was to describe the prevalence of diseases during pregnancy and the association between fetal exposure to the most frequent maternal diseases and the risk of preterm (PTB) and/or small for gestational age (SGA) newborns in an unselected sample of women who gave birth in South American countries.
    Methods: We conducted a descriptive, cross-sectional study including 56,232 mothers of non-malformed infants born between 2002 and 2016, using data from the Latin American Collaborative Study of Congenital Malformations (ECLAMC). Diseases with higher- than-expected PTB/SGA frequencies were identified. Odds ratios of confounding variables for diseases and birth outcomes were calculated with a multivariable logistic regression.
    Results: Of the 14 most reported diseases, hypertension, genitourinary infection, epilepsy, hypothyroidism, diabetes, and HIV/AIDS showed higher PTB and/or SGA frequencies. Advanced and low maternal age, previous fetal loss, low socioeconomic level, and African-American ancestry were associated with PTB, while advanced maternal age, primigravidity, previous fetal loss, low socioeconomic level, and African-American ancestry were associated with SGA. After adjusting for the associated variables, the identified illnesses maintained their association with PTB and all, except epilepsy, with SGA.
    Conclusion: The description of an unselected population of mothers allowed identifying the most frequent diseases occurring during gestation and their impact on pregnancy outcomes. Six diseases were associated with PTB and two with SGA newborns. To the best of our knowledge, there are no similar reports about women not intentionally selected by specific diseases during pregnancy in South American populations.
    MeSH term(s) Infant, Newborn ; Female ; Humans ; Pregnancy ; Cross-Sectional Studies ; Brazil
    Language English
    Publishing date 2022-12-05
    Publishing country Brazil
    Document type Journal Article
    ZDB-ID 2183366-7
    ISSN 1980-5497 ; 1980-5497
    ISSN (online) 1980-5497
    ISSN 1980-5497
    DOI 10.1590/1980-549720220043
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  10. Article: Genes, exposures, and interactions on preterm birth risk: an exploratory study in an Argentine population.

    Elias, Dario E / Santos, Maria R / Campaña, Hebe / Poletta, Fernando A / Heisecke, Silvina L / Gili, Juan A / Ratowiecki, Julia / Cosentino, Viviana / Uranga, Rocio / Málaga, Diana Rojas / Netto, Alice Brinckmann Oliveira / Brusius-Facchin, Ana Carolina / Saleme, César / Rittler, Mónica / Krupitzki, Hugo B / Camelo, Jorge S Lopez / Gimenez, Lucas G

    Journal of community genetics

    2022  Volume 13, Issue 6, Page(s) 557–565

    Abstract: Preterm birth (PTB) is the main condition related to perinatal morbimortality worldwide. The aim of this study was to identify associations of spontaneous PTB with genetic variants, exposures, and interactions between and within them. We carried out a ... ...

    Abstract Preterm birth (PTB) is the main condition related to perinatal morbimortality worldwide. The aim of this study was to identify associations of spontaneous PTB with genetic variants, exposures, and interactions between and within them. We carried out a retrospective case-control study including parental sociodemographic and obstetric data, and fetal genetic variants. We sequenced the coding and flanking regions of five candidate genes from the placental blood cord of 69 preterm newborns and 61 at term newborns. We identify the characteristics with the greatest predictive power of PTB using penalized regressions, in which we include exposures (E), genetic variants (G), and two-way interactions. Few prenatal visits (< 5) was the main predictor of PTB from 26 G, 35 E, 299 G × G, 564 E × E, and 875 G × E evaluated terms. Within the fetal genetic characteristics, we observed associations of rs4845397 (KCNN3, allele T) variant; G × G interaction between rs12621551 (COL4A3, allele T) and rs73993878 (COL4A3, allele A), which showed sensitivity to anemia; and G × G interaction between rs11680670 (COL4A3, allele T) and rs2074351 (PON1, allele A), which showed sensitivity to vaginal discharge. The results of this exploratory study suggest that social disparities and metabolic pathways linked to uterine relaxation, inflammation/infections, and collagen metabolism would be involved in PTB etiology. Future studies with a larger sample size are necessary to confirm these findings and to analyze a greater number of exposures.
    Language English
    Publishing date 2022-08-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2543127-4
    ISSN 1868-6001 ; 1868-310X
    ISSN (online) 1868-6001
    ISSN 1868-310X
    DOI 10.1007/s12687-022-00605-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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