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  1. Artikel: Preliminary Evidence of

    Lledó, Lourdes / Giménez-Pardo, Consuelo

    Pathogens (Basel, Switzerland)

    2021  Band 10, Heft 7

    Abstract: Limited information is available on the presence of rickettsial infection in animal reservoirs in Spain. Antibodies ... ...

    Abstract Limited information is available on the presence of rickettsial infection in animal reservoirs in Spain. Antibodies against
    Sprache Englisch
    Erscheinungsdatum 2021-07-03
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens10070836
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel: Preliminary Evidence of Rickettsia slovaca and Rickettsia conorii Infection in the Sera of Sheep, Dogs and Deer from an Area of Northern Spain

    Lledó, Lourdes / Giménez-Pardo, Consuelo

    Pathogens. 2021 July 03, v. 10, no. 7

    2021  

    Abstract: Limited information is available on the presence of rickettsial infection in animal reservoirs in Spain. Antibodies against Rickettsia slovaca and Rickettsia conorii were therefore sought in the sera of farm, domestic and wild animals (n = 223 samples) ... ...

    Abstract Limited information is available on the presence of rickettsial infection in animal reservoirs in Spain. Antibodies against Rickettsia slovaca and Rickettsia conorii were therefore sought in the sera of farm, domestic and wild animals (n = 223 samples) in an area of northern Spain. Indirect immunofluorescence assays showed: (A) 17/120 and 16/120 (14.2% and 13.3%) of serum samples from sheep (farm animals) reacted with R. slovaca and R. conorii antigens, respectively; (B) 10/73 and 10/73 (13.7% and 13.7%) of samples from dogs (domestic animals) did the same; (C) as did 22/30 and 20/30 (73.3% and 66.6%) of samples from deer (wild animals) (overall titre range: 1/40 to 1/1280). The prevalence of both types of infection was significantly greater in the wild animals than either the farm or domestic animals. The largest titres were recorded for R. slovaca in all three groups.
    Schlagwörter Rickettsia conorii ; Rickettsia slovaca ; blood serum ; deer ; farms ; fluorescent antibody technique ; rickettsial diseases ; sheep ; Spain
    Sprache Englisch
    Erscheinungsverlauf 2021-0703
    Erscheinungsort Multidisciplinary Digital Publishing Institute
    Dokumenttyp Artikel
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens10070836
    Datenquelle NAL Katalog (AGRICOLA)

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  3. Artikel ; Online: Epidemiological Study of Thogoto and Dhori Virus Infection in People Bitten by Ticks, and in Sheep, in an Area of Northern Spain.

    Lledó, Lourdes / Giménez-Pardo, Consuelo / Gegúndez, María Isabel

    International journal of environmental research and public health

    2020  Band 17, Heft 7

    Abstract: There is little information on Thogoto virus (THOV) and Dhori virus (DHOV)infection in Spain. A total of 283 serum samples from 150 human subjects (78 males, 72 females) bitten by ticks, as well as samples from 120 sheep (one per animal), were studied by ...

    Abstract There is little information on Thogoto virus (THOV) and Dhori virus (DHOV)infection in Spain. A total of 283 serum samples from 150 human subjects (78 males, 72 females) bitten by ticks, as well as samples from 120 sheep (one per animal), were studied by immunofluorescence assay. All human and animal subjects were from the province of Palencia in northern Spain. Eight human subjects had antibodies against THOV (seroprevalence: 5.3%) and six had antibodies against DHOV (seroprevalence: 4%); titers ranged between 1/32-1/256 and 1/32-1/128, respectively. No significant differences were seen in seroprevalence in terms of gender or age, although people with antibodies were significantly more likely to have had contact with livestock for professional reasons. One subject with an acute infection had IgM antibodies to both viruses and seroconverted to IgG. For the sheep, 24 serum samples were positive for antibodies to THOV (seroprevalence: 20%) and 32 for antibodies to DHOV (seroprevalence: 26.8%); titers ranged between 1/16 and 1/128. The seroprevalence of both viruses was significantly higher in animals < 4 years of age. Together, these results reveal the circulation of DHOV and THOV in humans and sheep in the province of Palencia. Sheep might be used as indicators of the presence of these organisms.
    Mesh-Begriff(e) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Animals ; Bites and Stings ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Orthomyxoviridae Infections/epidemiology ; Seroepidemiologic Studies ; Sheep/parasitology ; Sheep Diseases/epidemiology ; Spain ; Thogotovirus/pathogenicity ; Ticks ; Young Adult
    Sprache Englisch
    Erscheinungsdatum 2020-03-27
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph17072254
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  4. Artikel ; Online: Screening of Forestry Workers in Guadalajara Province (Spain) for Antibodies to

    Lledó, Lourdes / Giménez-Pardo, Consuelo / Gegúndez, María Isabel

    International journal of environmental research and public health

    2019  Band 16, Heft 22

    Abstract: ... Exposure ... ...

    Abstract Exposure to
    Mesh-Begriff(e) Adult ; Animals ; Antibodies, Bacterial/blood ; Antibodies, Viral/blood ; Borrelia burgdorferi/immunology ; Communicable Diseases ; Female ; Forestry ; Hantavirus/immunology ; Humans ; Lyme Disease/epidemiology ; Lymphocytic choriomeningitis virus/immunology ; Male ; Occupational Diseases/blood ; Occupational Diseases/diagnosis ; Rickettsia/immunology ; Spain/epidemiology
    Chemische Substanzen Antibodies, Bacterial ; Antibodies, Viral
    Sprache Englisch
    Erscheinungsdatum 2019-11-15
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ISSN 1660-4601
    ISSN (online) 1660-4601
    DOI 10.3390/ijerph16224500
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  5. Artikel ; Online: Wild Red Foxes (

    Lledó, Lourdes / Serrano, José Luis / Giménez-Pardo, Consuelo / Gegúndez, Isabel

    Journal of wildlife diseases

    2020  Band 56, Heft 3, Seite(n) 658–661

    Abstract: Three hundred and fourteen red foxes ( ...

    Abstract Three hundred and fourteen red foxes (
    Mesh-Begriff(e) Animals ; Antibodies, Viral ; Disease Reservoirs/veterinary ; Female ; Foxes/virology ; Hantavirus ; Hantavirus Infections/epidemiology ; Hantavirus Infections/veterinary ; Hantavirus Infections/virology ; Lymphocytic Choriomeningitis/epidemiology ; Lymphocytic Choriomeningitis/veterinary ; Lymphocytic Choriomeningitis/virology ; Lymphocytic choriomeningitis virus/immunology ; Male ; Rodentia/virology ; Sentinel Surveillance/veterinary ; Spain/epidemiology
    Chemische Substanzen Antibodies, Viral
    Sprache Englisch
    Erscheinungsdatum 2020-02-03
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 410709-3
    ISSN 1943-3700 ; 0090-3558
    ISSN (online) 1943-3700
    ISSN 0090-3558
    DOI 10.7589/2019-09-239
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  6. Artikel: Wild Red Foxes (Vulpes vulpes) as Sentinels of Rodent-Borne Hantavirus and Lymphocytic Choriomeningitis Virus in the Province of Soria, Northern Spain

    Lledó, Lourdes / Serrano, José Luis / Giménez-Pardo, Consuelo / Gegúndez, Isabel

    Journal of wildlife diseases. 2020 July 2, v. 56, no. 3

    2020  

    Abstract: Three hundred and fourteen red foxes (Vulpes vulpes) in the province of Soria, Spain, were examined for hantavirus and lymphocytic choriomeningitis virus (LCMV) infection (and were likely to have been infected by feeding on infected rodents). ... ...

    Abstract Three hundred and fourteen red foxes (Vulpes vulpes) in the province of Soria, Spain, were examined for hantavirus and lymphocytic choriomeningitis virus (LCMV) infection (and were likely to have been infected by feeding on infected rodents). Immunofluorescence and western blot assays confirmed 3.5% (11/314) to have antibodies to hantaviruses, and the immune fluorescence assay showed 2.2% (7/314) to have antibodies to LCMV. The serologic status of the animals showed no statistically significant association with sex or age. Although studies on the prevalence of hantaviruses and LCMV normally focus on rodents, our results showed that foxes can provide complementary information in determined areas.
    Schlagwörter Lymphocytic choriomeningitis mammarenavirus ; Orthohantavirus ; Vulpes vulpes ; Western blotting ; fluorescent antibody technique ; wildlife ; Spain
    Sprache Englisch
    Erscheinungsverlauf 2020-0702
    Umfang p. 658-661.
    Erscheinungsort Wildlife Disease Association
    Dokumenttyp Artikel
    Anmerkung NAL-AP-2-clean
    ZDB-ID 410709-3
    ISSN 1943-3700 ; 0090-3558
    ISSN (online) 1943-3700
    ISSN 0090-3558
    DOI 10.7589/2019-09-239
    Datenquelle NAL Katalog (AGRICOLA)

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  7. Artikel ; Online: Wild Red Foxes (Vulpes vulpes) as Sentinels of Parasitic Diseases in the Province of Soria, Northern Spain.

    Lledó, Lourdes / Giménez-Pardo, Consuelo / Saz, José Vicente / Serrano, José Luis

    Vector borne and zoonotic diseases (Larchmont, N.Y.)

    2015  Band 15, Heft 12, Seite(n) 743–749

    Abstract: Four hundred red foxes (Vulpes vulpes) were examined for ecto- (arthropods) and endoparasites (Leishmania spp., Trichinella spp., and intestinal parasites). Different species of flea (total prevalence, 40.50%), tick (16.25%), mite (7.25%), and fly (1.50%) ...

    Abstract Four hundred red foxes (Vulpes vulpes) were examined for ecto- (arthropods) and endoparasites (Leishmania spp., Trichinella spp., and intestinal parasites). Different species of flea (total prevalence, 40.50%), tick (16.25%), mite (7.25%), and fly (1.50%) were identified. The most prevalent flea was Pulex irritans (found on 29% of the foxes); the most prevalent tick, mite, and fly were Ixodes canisuga (on 5%), Sarcoptes scabiei (on 5.25%), and Hippobosca equina (on 1%), respectively. The endoparasites identified included Leishmania spp. (found in 12% of the foxes), Trichinella spp. (in 15.5%, with T. britovi the most prevalent species in 15.25%), Cestoda (in 72.75%, with Mesocestoides spp. the most prevalent in 69.50%), and intestinal ascarids (in 73.25%, with Ancylostoma caninum the most prevalent in 12.50%). No animal was free of parasites. The present results suggest that foxes can act as sentinels of diseases transmitted by ecto- and endoparasites.
    Mesh-Begriff(e) Animals ; Arthropods/classification ; Cestoda/isolation & purification ; Female ; Foxes/parasitology ; Geography ; Humans ; Leishmania/isolation & purification ; Male ; Parasitic Diseases/epidemiology ; Parasitic Diseases/parasitology ; Parasitic Diseases/transmission ; Sentinel Surveillance ; Siphonaptera/classification ; Spain/epidemiology ; Ticks/classification ; Trichinella/isolation & purification
    Sprache Englisch
    Erscheinungsdatum 2015-12
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2047199-3
    ISSN 1557-7759 ; 1530-3667
    ISSN (online) 1557-7759
    ISSN 1530-3667
    DOI 10.1089/vbz.2014.1766
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  8. Artikel ; Online: Antibodies to Rickettsia spp. and Borrelia burgdorferi in Spanish Wild Red Foxes (Vulpes vulpes).

    Lledó, Lourdes / Serrano, José Luis / Isabel Gegúndez, María / Giménez-Pardo, Consuelo / Saz, José Vicente

    Journal of wildlife diseases

    2016  Band 52, Heft 1, Seite(n) 122–125

    Abstract: We examined 314 red foxes (Vulpes vulpes) from the province of Soria, Spain, for Rickettsia typhi, Rickettsia slovaca, and Borrelia burgdorferi infection. Immunofluorescence assays showed 1.9% had antibodies to R. typhi, 6.7% had antibodies to R. slovaca, ...

    Abstract We examined 314 red foxes (Vulpes vulpes) from the province of Soria, Spain, for Rickettsia typhi, Rickettsia slovaca, and Borrelia burgdorferi infection. Immunofluorescence assays showed 1.9% had antibodies to R. typhi, 6.7% had antibodies to R. slovaca, and 8.3% had antibodies to B. burgdorferi. Serostatus was not correlated with sex or age. Because red foxes can be infected by Rickettsiae and B. burgdorferi, presence of red foxes may be and indicator for the presence of these pathogens.
    Mesh-Begriff(e) Animals ; Antibodies, Bacterial/blood ; Arachnid Vectors/microbiology ; Borrelia burgdorferi/immunology ; Communicable Diseases, Emerging/epidemiology ; Communicable Diseases, Emerging/transmission ; Communicable Diseases, Emerging/veterinary ; Disease Vectors/classification ; Female ; Foxes ; Lyme Disease/epidemiology ; Lyme Disease/transmission ; Lyme Disease/veterinary ; Male ; Prevalence ; Rickettsia/immunology ; Rickettsia Infections/epidemiology ; Rickettsia Infections/transmission ; Rickettsia Infections/veterinary ; Spain/epidemiology
    Chemische Substanzen Antibodies, Bacterial
    Sprache Englisch
    Erscheinungsdatum 2016-01
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 410709-3
    ISSN 1943-3700 ; 0090-3558
    ISSN (online) 1943-3700
    ISSN 0090-3558
    DOI 10.7589/2015-03-074
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  9. Artikel: High Seroprevalence Against SARS-CoV-2 Among Faculty of Medicine and Health Sciences Personnel and Students of the University of Alcalá, Spain: Contributing Factors.

    Pérez-Tanoira, Ramón / Lledó García, Lourdes / Torralba González de Suso, Miguel / Rodríguez Zapata, Manuel / Arroyo Serrano, Teresa / Giménez Pardo, Consuelo / Rodríguez Pedrosa, María Isabel / Romero Badía, Mª Nuria / Pérez-García, Felipe / González López, Patricia / Villaescusa García, Cristina / Cuadros González, Juan

    International journal of general medicine

    2021  Band 14, Seite(n) 7017–7024

    Abstract: Purpose: Seroprevalence against SARS-CoV-2 within university systems is poorly studied, making evidence-based discussions of educational system reopening difficult. Moreover, few studies evaluate how antibodies against SARS-CoV-2 are maintained over ... ...

    Abstract Purpose: Seroprevalence against SARS-CoV-2 within university systems is poorly studied, making evidence-based discussions of educational system reopening difficult. Moreover, few studies evaluate how antibodies against SARS-CoV-2 are maintained over time. We assessed serological response against the SARS-CoV-2 virus among our university students and staff.
    Patients and methods: In this prospective cohort study, seroprevalence was determined in 705 randomly selected volunteers, members of the Faculty of Medicine and Health Sciences of the University of Alcalá, using a chemiluminescent Siemens' SARS-CoV-2 immunoassay for total antibodies. Positive samples were tested for IgG and IgM/IgA using VIRCLIA
    Results: A total of 130 subjects showed anti-SARS-CoV-2 antibodies (18.5%, 95% CI, 15.8-21.5%). Of these, IgM/IgA was positive in 27 and indeterminate in 19; IgG was positive in 118, indeterminate in 1. After 23 weeks, among 102 volunteers remeasured, IgG became undetectable in 6. Presence of antibodies was associated, in multivariable logistic regression, with exposure to infected patients (31.3%) [OR 1.84, 95% CI, 1.14-2.96; P = 0.012], presence of COVID-19 symptoms (52.4%) [OR 6.88, 95% CI, 4.28-11.06; P < 0.001], and confirmed earlier infection (82.9%) [OR 11.87, 95% CI, 4.26-33.07; P < 0.001].
    Conclusions: The faculty of medicine and health sciences personnel and students of our university showed a high infection rate for SARS-CoV-2 during 2020 associated with providing clinical care to infected patients. This emphasizes the importance of the performance of continuous surveillance methods of the most exposed health personnel, including health science students.
    Sprache Englisch
    Erscheinungsdatum 2021-10-21
    Erscheinungsland New Zealand
    Dokumenttyp Journal Article
    ZDB-ID 2452220-X
    ISSN 1178-7074
    ISSN 1178-7074
    DOI 10.2147/IJGM.S332803
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  10. Artikel ; Online: A seventeen-year epidemiological surveillance study of Borrelia burgdorferi infections in two provinces of northern Spain.

    Lledó, Lourdes / Gegúndez, María Isabel / Giménez-Pardo, Consuelo / Álamo, Rufino / Fernández-Soto, Pedro / Nuncio, María Sofia / Saz, José Vicente

    International journal of environmental research and public health

    2014  Band 11, Heft 2, Seite(n) 1661–1672

    Abstract: This paper reports a 17-year seroepidemiological surveillance study of Borrelia burgdorferi infection, performed with the aim of improving our knowledge of the epidemiology of this pathogen. Serum samples (1,179) from patients (623, stratified with ... ...

    Abstract This paper reports a 17-year seroepidemiological surveillance study of Borrelia burgdorferi infection, performed with the aim of improving our knowledge of the epidemiology of this pathogen. Serum samples (1,179) from patients (623, stratified with respect to age, sex, season, area of residence and occupation) bitten by ticks in two regions of northern Spain were IFA-tested for B. burgdorferi antibodies. Positive results were confirmed by western blotting. Antibodies specific for B. burgdorferi were found in 13.3% of the patients; 7.8% were IgM positive, 9.6% were IgG positive, and 4.33% were both IgM and IgG positive. Five species of ticks were identified in the seropositive patients: Dermacentor marginatus (41.17% of such patients) Dermacentor reticulatus (11.76%), Rhiphicephalus sanguineus (17.64%), Rhiphicephalus turanicus (5.88%) and Ixodes ricinus (23.52%). B. burgdorferi DNA was sought by PCR in ticks when available. One tick, a D. reticulatus male, was found carrying the pathogen. The seroprevalence found was similar to the previously demonstrated in similar studies in Spain and other European countries.
    Mesh-Begriff(e) Adolescent ; Adult ; Aged ; Aged, 80 and over ; Animals ; Antibodies, Bacterial/biosynthesis ; Antibodies, Bacterial/blood ; Arachnid Vectors/microbiology ; Borrelia burgdorferi/immunology ; Borrelia burgdorferi/isolation & purification ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Ixodidae/microbiology ; Lyme Disease/epidemiology ; Lyme Disease/immunology ; Male ; Middle Aged ; Population Surveillance ; Seroepidemiologic Studies ; Spain/epidemiology ; Young Adult
    Chemische Substanzen Antibodies, Bacterial
    Sprache Englisch
    Erscheinungsdatum 2014-01-30
    Erscheinungsland Switzerland
    Dokumenttyp Journal Article
    ZDB-ID 2175195-X
    ISSN 1660-4601 ; 1661-7827
    ISSN (online) 1660-4601
    ISSN 1661-7827
    DOI 10.3390/ijerph110201661
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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