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  1. Article ; Online: Traditional vs. Microfluidic Synthesis of ZnO Nanoparticles.

    Popa, Maria Leila / Preda, Manuela Daniela / Neacșu, Ionela Andreea / Grumezescu, Alexandru Mihai / Ginghină, Octav

    International journal of molecular sciences

    2023  Volume 24, Issue 3

    Abstract: Microfluidics provides a precise synthesis of micro-/nanostructures for various applications, including bioengineering and medicine. In this review article, traditional and microfluidic synthesis methods of zinc oxide (ZnO) are compared concerning ... ...

    Abstract Microfluidics provides a precise synthesis of micro-/nanostructures for various applications, including bioengineering and medicine. In this review article, traditional and microfluidic synthesis methods of zinc oxide (ZnO) are compared concerning particle size distribution, morphology, applications, reaction parameters, used reagents, and microfluidic device materials. Challenges of traditional synthesis methods are reviewed in a manner where microfluidic approaches may overcome difficulties related to synthesis precision, bulk materials, and reproducibility.
    MeSH term(s) Microfluidics/methods ; Zinc Oxide/chemistry ; Reproducibility of Results ; Nanoparticles/chemistry ; Nanostructures/chemistry
    Chemical Substances Zinc Oxide (SOI2LOH54Z)
    Language English
    Publishing date 2023-01-18
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24031875
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Antimicrobial Clothing Based on Electrospun Fibers with ZnO Nanoparticles.

    Preda, Manuela Daniela / Popa, Maria Leila / Neacșu, Ionela Andreea / Grumezescu, Alexandru Mihai / Ginghină, Octav

    International journal of molecular sciences

    2023  Volume 24, Issue 2

    Abstract: There has been a surge in interest in developing protective textiles and clothes to protect wearers from risks such as chemical, biological, heat, UV, pollution, and other environmental factors. Traditional protective textiles have strong water ... ...

    Abstract There has been a surge in interest in developing protective textiles and clothes to protect wearers from risks such as chemical, biological, heat, UV, pollution, and other environmental factors. Traditional protective textiles have strong water resistance but lack breathability and have a limited capacity to remove water vapor and moisture. Electrospun fibers and membranes have shown enormous promise in developing protective materials and garments. Textiles made up of electrospun fibers and membranes can provide thermal comfort and protection against a wide range of environmental threats. Because of their multifunctional properties, such as semi-conductivity, ultraviolet absorption, optical transparency, and photoluminescence, their low toxicity, biodegradability, low cost, and versatility in achieving diverse shapes, ZnO-based nanomaterials are a subject of increasing interest in the current review. The growing uses of electrospinning in the development of breathable and protective textiles are highlighted in this review.
    MeSH term(s) Zinc Oxide/chemistry ; Textiles ; Anti-Infective Agents/pharmacology ; Nanoparticles ; Clothing
    Chemical Substances Zinc Oxide (SOI2LOH54Z) ; Anti-Infective Agents
    Language English
    Publishing date 2023-01-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24021629
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Surgical Outcome in Bilateral Inguinal Hernia Repair: Laparoscopic Total Extraperitoneal Approach (TEP) as Best Approach?

    Ungureanu, Claudiu-Octavian / Ginghina, Octav / Stanculea, Floris / Iosifescu, Razvan / Cristian, Dan / Grigorean, Valentin Titus / Popescu, Razvan-Ionut / Dobre, Ramona / Iordache, Niculae

    Maedica

    2024  Volume 18, Issue 4, Page(s) 598–606

    Abstract: Introduction: ...

    Abstract Introduction:
    Language English
    Publishing date 2024-02-08
    Publishing country Romania
    Document type Editorial
    ZDB-ID 2399972-X
    ISSN 2069-6116 ; 1841-9038
    ISSN (online) 2069-6116
    ISSN 1841-9038
    DOI 10.26574/maedica.2023.18.4.598
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Ruptured Recurrent Interstitial Ectopic Pregnancy Successfully Managed by Laparoscopy.

    Ungureanu, Claudiu Octavian / Stanculea, Floris Cristian / Iordache, Niculae / Georgescu, Teodor Florin / Ginghina, Octav / Mihailov, Raul / Vacaroiu, Ileana Adela / Georgescu, Dragos Eugen

    Diagnostics (Basel, Switzerland)

    2024  Volume 14, Issue 5

    Abstract: Ectopic pregnancies are a frequently encountered cause of first-trimester metrorrhagia. They occur when an embryo is implanted and grows outside the normal uterine space. Uncommonly, the embryo can be implanted in the intramural portion of the uterine ... ...

    Abstract Ectopic pregnancies are a frequently encountered cause of first-trimester metrorrhagia. They occur when an embryo is implanted and grows outside the normal uterine space. Uncommonly, the embryo can be implanted in the intramural portion of the uterine tube, a condition referred to as interstitial localization. This specific type of ectopic pregnancy may have an unpredictable course, potentially leading to severe uterine rupture and catastrophic bleeding if not promptly diagnosed and managed. We present a rare case of a multiparous 36-year-old female patient who underwent pelvic ultrasonography in the emergency department for intense pelvic pain associated with hypotension and moderate anemia. A history of right salpingectomy for a ruptured tubal ectopic pregnancy 10 years previously was noted. High beta-HCG levels were also detected. A pelvic ultrasound allowed us to suspect a ruptured ectopic interstitial pregnancy at 8 weeks of amenorrhea. An association with hemoperitoneum was suspected, and an emergency laparoscopy was performed. The condition was confirmed intraoperatively, and the patient underwent a right corneal wedge resection with suture of the uterine myometrium. The postoperative course was uneventful, and the patient was discharged on the fourth day postoperatively. Interstitial ectopic pregnancy is a rare yet extremely perilous situation. Timely ultrasound-based diagnosis is crucial as it can enable conservative management with Methotrexate. Delayed diagnosis can lead to uterine rupture with consecutive surgery based on a transection of the pregnancy and cornual uterine resection.
    Language English
    Publishing date 2024-02-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2662336-5
    ISSN 2075-4418
    ISSN 2075-4418
    DOI 10.3390/diagnostics14050506
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Gracilis Muscle Flap Repair for Rectovesical Fistula After Robotic Prostatectomy.

    Grama, Florin A / Muraru, Dragos / Chitul, Andrei / Bezede, Cosmin / Ciofic, Emilica / Chitul, Mirela / Ginghina, Octav / Cristian, Daniel

    Diseases of the colon and rectum

    2024  Volume 67, Issue 5, Page(s) e288

    MeSH term(s) Male ; Humans ; Robotic Surgical Procedures ; Gracilis Muscle/surgery ; Rectal Fistula/etiology ; Rectal Fistula/surgery ; Surgical Flaps ; Prostatectomy/adverse effects ; Urinary Bladder Fistula/surgery ; Urinary Fistula/surgery
    Language English
    Publishing date 2024-01-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 212581-x
    ISSN 1530-0358 ; 0012-3706
    ISSN (online) 1530-0358
    ISSN 0012-3706
    DOI 10.1097/DCR.0000000000003116
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Laparoscopic approach of inguinal hernia associated with adult cryptorchidism: case series and literature review.

    Ungureanu, Claudiu / Stanculea, Floris / Ginghina, Octav / Cristian, Daniel A / Grigorean, Valentin T / Popescu, Razvan / Georgescu, Dragos / Iordache, Niculae

    Journal of surgical case reports

    2024  Volume 2024, Issue 4, Page(s) rjae232

    Abstract: Cryptorchidism is defined as the extra-scrotal position of the testes. It is a common disorder in male children, but rarely in adult patients. The association of cryptorchidism with hernia is a common finding in childhood, but is not frequent in adults ... ...

    Abstract Cryptorchidism is defined as the extra-scrotal position of the testes. It is a common disorder in male children, but rarely in adult patients. The association of cryptorchidism with hernia is a common finding in childhood, but is not frequent in adults or the elderly. Herein, we report a series of three cases (28-, 24-, and 34-year-old men) of adult inguinal hernia combined with cryptorchidism successfully managed by laparoscopic surgery under the same operative view. Laparoscopic transabdominal preperitoneal repair and orchiectomy were performed in all patients. No complications occurred in the postoperative period, and the patients were discharged on the first or second postoperative day. Pathological examination of the specimens revealed atrophic testes without malignancy. No hernia recurrence was observed during follow-up. The laparoscopic approach in the combined pathology of inguinal hernia and cryptorchidism is feasible in adult patients and has multiple advantages in terms of diagnosis and management.
    Language English
    Publishing date 2024-04-08
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjae232
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Conference proceedings: Ablate, stent and repeat: Feasibility, clinical success and safety profile of intraductal radiofrequency ablation in the management of inoperable perihilar cholangiocarcinoma patients – interim analysis of the COMBO-RFA randomized clinical trial

    Birligea, M. / Diaconu, C. / Voiosu, A. / Bengus, A. / Dumea, E. / Popp, C. / Galateanu, B. / Hudita, A. / Pantelimon, I. / Draghici, T. / Rouhani, F. / Ginghina, O. / Mateescu, R. B. / Voiosu, T.

    Endoscopy

    2024  Volume 56, Issue S 02

    Event/congress ESGE Days 2024, Berlin, Germany, 2024-04-25
    Language English
    Publishing date 2024-04-01
    Publisher Georg Thieme Verlag KG
    Publishing place Stuttgart ; New York
    Document type Article ; Conference proceedings
    ZDB-ID 80120-3
    ISSN 1438-8812 ; 0013-726X
    ISSN (online) 1438-8812
    ISSN 0013-726X
    DOI 10.1055/s-0044-1782948
    Database Thieme publisher's database

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  8. Article ; Online: Delayed Coloanal (Turnbull-Cutait) After Leak of Conventional Coloanal Anastomosis: Redo Surgery.

    Grama, Florin / Chitul, Andrei / Dutei, Catalin / Bezede, Cosmin / Ciofic, Emilica / Cristian, Daniel / Ginghina, Octav

    Diseases of the colon and rectum

    2022  Volume 66, Issue 2, Page(s) e50

    MeSH term(s) Humans ; Anastomosis, Surgical ; Digestive System Surgical Procedures ; Intestines/surgery ; Rectal Neoplasms/surgery ; Colon/surgery ; Anal Canal/surgery
    Language English
    Publishing date 2022-09-22
    Publishing country United States
    Document type Journal Article
    ZDB-ID 212581-x
    ISSN 1530-0358 ; 0012-3706
    ISSN (online) 1530-0358
    ISSN 0012-3706
    DOI 10.1097/DCR.0000000000002438
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Surgical Approach to Bilateral Inguinal Hernia. A Case-Control Study.

    Ungureanu, Claudiu-Octavian / Ginghina, Octav / Stanculea, Floris / Vacaroiu, Ileana / Ene, Cosmin / Iosifescu, Razvan / Georgescu, Dragoà Eugen / Cristian, Daniel Alin / Grigorean, Valentin Titus / Iordache, Niculae

    Chirurgia (Bucharest, Romania : 1990)

    2024  Volume 118, Issue 6, Page(s) 642–653

    Abstract: Introduction: ...

    Abstract Introduction:
    MeSH term(s) Humans ; Hernia, Inguinal/surgery ; Case-Control Studies ; Retrospective Studies ; Treatment Outcome ; Laparoscopy/methods ; Herniorrhaphy/methods ; Anticoagulants
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2024-01-16
    Publishing country Romania
    Document type Journal Article
    ZDB-ID 419244-8
    ISSN 1842-368X ; 1221-9118 ; 0009-4730 ; 0377-5003
    ISSN (online) 1842-368X
    ISSN 1221-9118 ; 0009-4730 ; 0377-5003
    DOI 10.21614/chirurgia.2023.v.118.i.6.p.642
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Current Landscape in Organic Nanosized Materials Advances for Improved Management of Colorectal Cancer Patients.

    Ginghină, Octav / Hudiță, Ariana / Zaharia, Cătălin / Tsatsakis, Aristidis / Mezhuev, Yaroslav / Costache, Marieta / Gălățeanu, Bianca

    Materials (Basel, Switzerland)

    2021  Volume 14, Issue 9

    Abstract: Globally, colorectal cancer (CRC) ranks as one of the most prevalent types of cancers at the moment, being the second cause of cancer-related deaths. The CRC chemotherapy backbone is represented by 5-fluorouracil, oxaliplatin, irinotecan, and their ... ...

    Abstract Globally, colorectal cancer (CRC) ranks as one of the most prevalent types of cancers at the moment, being the second cause of cancer-related deaths. The CRC chemotherapy backbone is represented by 5-fluorouracil, oxaliplatin, irinotecan, and their combinations, but their administration presents several serious disadvantages, such as poor bioavailability, lack of tumor specificity, and susceptibility to multidrug resistance. To address these limitations, nanomedicine has arisen as a powerful tool to improve current chemotherapy since nanosized carriers hold great promise in improving the stability and solubility of the drug payload and enhancing the active concentration of the drug that reaches the tumor tissue, increasing, therefore, the safety and efficacy of the treatment. In this context, the present review offers an overview of the most recent advances in the development of nanosized drug-delivery systems as smart therapeutic tools in CRC management and highlights the emerging need for improving the existing in vitro cancer models to reduce animal testing and increase the success of nanomedicine in clinical trials.
    Language English
    Publishing date 2021-05-08
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma14092440
    Database MEDical Literature Analysis and Retrieval System OnLINE

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