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  1. Article ; Online: Monitoring avian influenza in mammals with real-time data.

    Branda, Francesco / Giovanetti, Marta / Scarpa, Fabio / Ciccozzi, Massimo

    Pathogens and global health

    2024  , Page(s) 1–5

    Language English
    Publishing date 2024-02-27
    Publishing country England
    Document type Journal Article
    ZDB-ID 2625162-0
    ISSN 2047-7732 ; 2047-7724
    ISSN (online) 2047-7732
    ISSN 2047-7724
    DOI 10.1080/20477724.2024.2323843
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

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  2. Article ; Online: Global transmission suitability maps for dengue virus transmitted by Aedes aegypti from 1981 to 2019.

    Nakase, Taishi / Giovanetti, Marta / Obolski, Uri / Lourenço, José

    Scientific data

    2023  Volume 10, Issue 1, Page(s) 275

    Abstract: Mosquito-borne viruses increasingly threaten human populations due to accelerating changes in climate, human and mosquito migration, and land use practices. Over the last three decades, the global distribution of dengue has rapidly expanded, causing ... ...

    Abstract Mosquito-borne viruses increasingly threaten human populations due to accelerating changes in climate, human and mosquito migration, and land use practices. Over the last three decades, the global distribution of dengue has rapidly expanded, causing detrimental health and economic problems in many areas of the world. To develop effective disease control measures and plan for future epidemics, there is an urgent need to map the current and future transmission potential of dengue across both endemic and emerging areas. Expanding and applying Index P, a previously developed mosquito-borne viral suitability measure, we map the global climate-driven transmission potential of dengue virus transmitted by Aedes aegypti mosquitoes from 1981 to 2019. This database of dengue transmission suitability maps and an R package for Index P estimations are offered to the public health community as resources towards the identification of past, current and future transmission hotspots. These resources and the studies they facilitate can contribute to the planning of disease control and prevention strategies, especially in areas where surveillance is unreliable or non-existent.
    MeSH term(s) Animals ; Humans ; Aedes ; Dengue/epidemiology ; Dengue Virus ; Flavivirus ; Mosquito Vectors
    Language English
    Publishing date 2023-05-12
    Publishing country England
    Document type Dataset ; Journal Article
    ZDB-ID 2775191-0
    ISSN 2052-4463 ; 2052-4463
    ISSN (online) 2052-4463
    ISSN 2052-4463
    DOI 10.1038/s41597-023-02170-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Comprehensive Analysis of HIV-1 Integrase Resistance-Related Mutations in African Countries.

    Branda, Francesco / Giovanetti, Marta / Sernicola, Leonardo / Farcomeni, Stefania / Ciccozzi, Massimo / Borsetti, Alessandra

    Pathogens (Basel, Switzerland)

    2024  Volume 13, Issue 2

    Abstract: The growing emergence of non-nucleoside reverse transcriptase inhibitor (NNRTI) HIV drug resistance in sub-Saharan Africa (SSA) led to the World Health Organization (WHO) recommending, in 2018, a transition to dolutegravir (DTG) as a first-line ... ...

    Abstract The growing emergence of non-nucleoside reverse transcriptase inhibitor (NNRTI) HIV drug resistance in sub-Saharan Africa (SSA) led to the World Health Organization (WHO) recommending, in 2018, a transition to dolutegravir (DTG) as a first-line antiretroviral therapy (ART) in SSA. The broad HIV-1 genetic diversity in SSA could shape DTG effectiveness and the pattern of drug resistance mutations (DRMs) in this region. This study evaluated HIV-1 integrase (IN) DRMs and conserved regions among published groups M, N, O, and P HIV-1 sequences spanning forty years of the HIV epidemic during the transition of DTG-based ART. Overall, we found low levels of integrase strand transfer inhibitor (INSTI)-DRMs (<1%) across HIV groups between the years 1983 and 2023; however, it was unexpected to detect DRMs at statistically significantly higher frequencies in pre-INSTI (1983-2007) than in the INSTI (2008-2023) era. The variability of accessory INSTI-DRMs depended on the HIV subtypes, with implications for susceptibility to DTG. Our findings provide new perspectives on the molecular epidemiology and drug resistance profiles of INSTIs in SSA, emphasizing the need for ongoing surveillance and customized treatment approaches to address the continent's varied HIV subtypes and changing resistance patterns.
    Language English
    Publishing date 2024-01-24
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2695572-6
    ISSN 2076-0817
    ISSN 2076-0817
    DOI 10.3390/pathogens13020102
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Emerging threats: Is highly pathogenic avian influenza A(H5N1) in dairy herds a prelude to a new pandemic?

    Branda, Francesco / Romano, Chiara / Giovanetti, Marta / Ciccozzi, Alessandra / Ciccozzi, Massimo / Scarpa, Fabio

    Travel medicine and infectious disease

    2024  Volume 59, Page(s) 102721

    Language English
    Publishing date 2024-04-07
    Publishing country Netherlands
    Document type Letter
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2024.102721
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6236: Show issues Location:
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  5. Article: Mpox: An Overview of Pathogenesis, Diagnosis, and Public Health Implications.

    Branda, Francesco / Romano, Chiara / Ciccozzi, Massimo / Giovanetti, Marta / Scarpa, Fabio / Ciccozzi, Alessandra / Maruotti, Antonello

    Journal of clinical medicine

    2024  Volume 13, Issue 8

    Abstract: Mpox, caused by viruses of the genus Orthopoxvirus, is an emerging threat to human and animal health. With increasing urbanization and more frequent interaction between humans and wild animals, the risk of Mpox transmission to humans has increased ... ...

    Abstract Mpox, caused by viruses of the genus Orthopoxvirus, is an emerging threat to human and animal health. With increasing urbanization and more frequent interaction between humans and wild animals, the risk of Mpox transmission to humans has increased significantly. This review aims to examine in depth the epidemiology, pathogenesis, and diagnosis of Mpox, with a special focus on recent discoveries and advances in understanding the disease. Molecular mechanisms involved in viral replication will be examined, as well as risk factors associated with interspecific transmission and spread of the disease in human populations. Currently available diagnostic methods will also be discussed, with a critical analysis of their limitations and possible future directions for improving the accuracy and timeliness of diagnosis. Finally, this review will explore the public health implications associated with Mpox, emphasizing the importance of epidemiological surveillance, vaccination, and emergency preparedness to prevent and manage possible outbreaks. Understanding the epidemiology and control strategies for Mpox is critical to protecting the health of human and animal communities and mitigating the risk of interspecific transmission and spread of the disease.
    Language English
    Publishing date 2024-04-12
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662592-1
    ISSN 2077-0383
    ISSN 2077-0383
    DOI 10.3390/jcm13082234
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Molecular Mimicry between hPF4 and SARS-CoV-2 Spike Protein: Response to Comment.

    Benvenuto, Domenico / Carnevale, Sergio / Giovanetti, Marta / Ciccozzi, Massimo / Broccolo, Francesco

    Seminars in thrombosis and hemostasis

    2022  Volume 49, Issue 1, Page(s) 106–107

    MeSH term(s) Humans ; COVID-19/metabolism ; COVID-19/virology ; Molecular Mimicry ; Protein Binding ; SARS-CoV-2/chemistry ; Spike Glycoprotein, Coronavirus/chemistry ; Platelet Factor 4/chemistry
    Chemical Substances Spike Glycoprotein, Coronavirus ; spike protein, SARS-CoV-2 ; Platelet Factor 4 (37270-94-3)
    Language English
    Publishing date 2022-06-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 196901-8
    ISSN 1098-9064 ; 0094-6176
    ISSN (online) 1098-9064
    ISSN 0094-6176
    DOI 10.1055/s-0042-1744280
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1259: Show issues Location:
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  7. Article ; Online: Is Molecular Mimicry between hPF4 and SARS-CoV-2 Spike Protein a Potential Basis for Autoimmune Responses in Vaccinated and Naturally Infected Patients?

    Carnevale, Sergio / Giovanetti, Marta / Benvenuto, Domenico / Ciccozzi, Massimo / Broccolo, Francesco

    Seminars in thrombosis and hemostasis

    2022  Volume 49, Issue 1, Page(s) 103–104

    MeSH term(s) Humans ; Autoimmunity ; COVID-19 ; Molecular Mimicry ; SARS-CoV-2 ; Spike Glycoprotein, Coronavirus
    Chemical Substances Spike Glycoprotein, Coronavirus ; spike protein, SARS-CoV-2 ; ZNF85 protein, human
    Language English
    Publishing date 2022-01-12
    Publishing country United States
    Document type Journal Article
    ZDB-ID 196901-8
    ISSN 1098-9064 ; 0094-6176
    ISSN (online) 1098-9064
    ISSN 0094-6176
    DOI 10.1055/s-0041-1742092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Detection of SARS-CoV-2 Alpha variant in a severely immunocompromised HIV-1-infected patient in the omicron era.

    Messali, Serena / Giovanetti, Marta / Ciccozzi, Massimo / Caruso, Arnaldo / Caccuri, Francesca

    The new microbiologica

    2022  Volume 45, Issue 4

    Abstract: Persistence of detectable viral RNA does not depend on the symptomatic status of the patients. Here we describe the case of a strongly immunocompromised patient living with a prolonged SARS-CoV-2 Alpha variant infection without showing any symptoms. The ... ...

    Abstract Persistence of detectable viral RNA does not depend on the symptomatic status of the patients. Here we describe the case of a strongly immunocompromised patient living with a prolonged SARS-CoV-2 Alpha variant infection without showing any symptoms. The importance of our findings is that the persistence of infection with an old SARS-CoV-2 strain, in an immunocompromised host, may allow recombination events generating new viral variants whose pathogenicity cannot be predicted. Our observation calls for the urgent need for continuous monitoring of SARS-CoV-2 genomic evolution in immunocompromised patients.
    Language English
    Publishing date 2022-05-23
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 756168-4
    ISSN 1121-7138 ; 0391-5352
    ISSN 1121-7138 ; 0391-5352
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Letter to the editor: Atypical weather is associated with the 2022 early start of West Nile virus transmission in Italy.

    Lourenço, José / Pinotti, Francesco / Nakase, Taishi / Giovanetti, Marta / Obolski, Uri

    Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin

    2022  Volume 27, Issue 34

    MeSH term(s) Animals ; Culicidae ; Humans ; Italy/epidemiology ; Mosquito Vectors ; Weather ; West Nile Fever ; West Nile virus/genetics
    Language English
    Publishing date 2022-08-26
    Publishing country Sweden
    Document type Letter ; Comment
    ZDB-ID 1338803-4
    ISSN 1560-7917 ; 1025-496X
    ISSN (online) 1560-7917
    ISSN 1025-496X
    DOI 10.2807/1560-7917.ES.2022.27.34.2200662
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 5066: Show issues Location:
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  10. Article ; Online: First detection of SARS-CoV-2 BA.2.86.1 in Italy.

    Caccuri, Francesca / Messali, Serena / Scarpa, Fabio / Giovanetti, Marta / Ciccozzi, Massimo / Caruso, Arnaldo

    Journal of medical virology

    2023  Volume 95, Issue 10, Page(s) e29175

    MeSH term(s) Humans ; SARS-CoV-2/genetics ; COVID-19 ; Italy/epidemiology
    Language English
    Publishing date 2023-10-16
    Publishing country United States
    Document type Letter
    ZDB-ID 752392-0
    ISSN 1096-9071 ; 0146-6615
    ISSN (online) 1096-9071
    ISSN 0146-6615
    DOI 10.1002/jmv.29175
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