Article ; Online: No fitness cost entailed by type VI secretion system synthesis, assembly, contraction, or disassembly in enteroaggregative
2023 Volume 205, Issue 12, Page(s) e0035723
Abstract: Importance: Bacteria use weapons to deliver effectors into target cells. One of these weapons, the type VI secretion system (T6SS), assembles a contractile tail acting as a spring to propel a toxin-loaded needle. Due to its size and mechanism of action, ...
| Abstract | Importance: Bacteria use weapons to deliver effectors into target cells. One of these weapons, the type VI secretion system (T6SS), assembles a contractile tail acting as a spring to propel a toxin-loaded needle. Due to its size and mechanism of action, the T6SS was intuitively thought to be energetically costly. Here, using a combination of mutants and growth measurements in liquid medium, on plates, and in competition experiments, we show that the T6SS does not entail a growth cost to enteroaggregative |
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| MeSH term(s) | Escherichia coli/genetics ; Type VI Secretion Systems/genetics ; Escherichia coli Proteins/genetics ; Bacterial Proteins | |||||
| Chemical Substances | Type VI Secretion Systems ; Escherichia coli Proteins ; Bacterial Proteins | |||||
| Language | English | |||||
| Publishing date | 2023-11-16 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article ; Research Support, Non-U.S. Gov't | |||||
| ZDB-ID | 2968-3 | |||||
| ISSN | 1098-5530 ; 0021-9193 | |||||
| ISSN (online) | 1098-5530 | |||||
| ISSN | 0021-9193 | |||||
| DOI | 10.1128/jb.00357-23 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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