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Article ; Online: Comparison of the adolescent pregnancy outcomes between refugees and Turkish citizens.

Arslan, Oğuz / Giray, Burak / Tuğ, Niyazi

2024 Volume 66, Issue 1, Page(s) 32–41

Abstract: Background: Adolescent pregnant women have significant risk factors in terms of preterm birth, low birth weight, gestational and neonatal complications, and neonatal and infant deaths. In many countries, living as a refugee differs from living as a ... ...

Abstract	Background: Adolescent pregnant women have significant risk factors in terms of preterm birth, low birth weight, gestational and neonatal complications, and neonatal and infant deaths. In many countries, living as a refugee differs from living as a local citizen regarding education level, access to health services, and lifestyle. We aimed to compare the obstetric, perinatal, and neonatal outcomes of Turkish and refugee adolescent pregnant women admitted to a tertiary maternity center. Methods: The study was planned as a retrospective cross-sectional. We included adolescent pregnant women who delivered between February 2018 and August 2023. Adolescent pregnant women were divided into two groups, the Turkish group and the Syrian refugee group, and compared with each other. Results: One thousand and fifty-one Turkish and 742 refugee adolescent pregnant women were included in the study. Adolescent pregnancy rates are higher in refugees than in the Turkish group (p < 0.001). We found that maternal age (p < 0.001), preeclampsia rates (p=0.029), gestational age at delivery (p < 0.001), and cesarean delivery rates (p=0.02) were lower in refugee adolescent pregnant women. Furthermore, we found that the anemia rates (p < 0.001) and low birth weight newborn rates (p = 0.011) were higher in refugee adolescent pregnant women. Conclusions: Enhancing the outcomes of adolescent pregnancies among refugees necessitates a heightened focus on education regarding sexual reproduction, increased prenatal follow-ups, and enhanced training in family planning.
MeSH term(s)	Adolescent ; Pregnancy ; Female ; Infant, Newborn ; Humans ; Pregnancy in Adolescence ; Refugees ; Retrospective Studies ; Cross-Sectional Studies ; Premature Birth/epidemiology ; Pregnancy Outcome/epidemiology
Language	English
Publishing date	2024-03-25
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	123487-0
ISSN	2791-6421 ; 0041-4301
ISSN (online)	2791-6421
ISSN	0041-4301
DOI	10.24953/turkjped.2023.812
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Article ; Online: The characteristics of the residual disease after cervical conization: A retrospective analysis from a tertiary gynecological cancer center.

Giray, Burak / Kabaca, Canan / Uzun, Mine Guray

Indian journal of cancer

2023 Volume 60, Issue 3, Page(s) 390–395

Abstract: Background: Patients with a biopsy-confirmed cervical intraepithelial neoplasia 2 and 3 have an increased risk of disease progression to invasive cancer and should be treated with an excisional method. However, after treatment with an excisional method, ...

Abstract	Background: Patients with a biopsy-confirmed cervical intraepithelial neoplasia 2 and 3 have an increased risk of disease progression to invasive cancer and should be treated with an excisional method. However, after treatment with an excisional method, a high-grade residual lesion may remain in patients with positive surgical margins. We aimed to investigate the risk factors for a residual lesion in patients with a positive surgical margin after cervical cold knife conization. Methods: Records of 1008 patients who underwent conization at a tertiary gynecological cancer center were retrospectively reviewed. One hundred and thirteen patients with a positive surgical margin after cold knife conization were included in the study. We have retrospectively analyzed the characteristics of the patients treated with re-conization or hysterectomy. Results: Residual disease was identified in 57 (50.4%) patients. The mean age of the patients with residual disease was 42.47 ± 8.75 years. Age greater than 35 years (P = 0.002; OR, 4.926; 95%CI [Confidence Interval] - 1.681-14.441), more than one involved quadrant (P = 0.003; OR, 3.200; 95% CI - 1.466-6.987), and glandular involvement (P = 0.002; OR, 3.348; 95% CI - 1.544-7.263) were risk factors for residual disease. The rate of high-grade lesion positivity in post-conization endocervical biopsy at initial conization was similar between patients with and without residual disease (P = 0.16). The final pathology of the residual disease was microinvasive cancer in four patients (3.5%) and invasive cancer in one patient (0.9%). Conclusion: In conclusion, residual disease is found in about half of the patients with a positive surgical margin. In particular, we found that age greater than 35 years, glandular involvement, and more than 1 involved quadrant were associated with the residual disease.
MeSH term(s)	Female ; Humans ; Adult ; Middle Aged ; Conization/methods ; Uterine Cervical Neoplasms/epidemiology ; Uterine Cervical Neoplasms/surgery ; Uterine Cervical Neoplasms/pathology ; Retrospective Studies ; Margins of Excision ; Uterine Cervical Dysplasia ; Neoplasm, Residual/surgery
Chemical Substances	CI 987
Language	English
Publishing date	2023-03-02
Publishing country	India
Document type	Journal Article
ZDB-ID	410194-7
ISSN	1998-4774 ; 0019-509X
ISSN (online)	1998-4774
ISSN	0019-509X
DOI	10.4103/ijc.IJC_238_20
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Article ; Online: SARS-CoV-2 and mutation RT-qPCR test positivity correlation with ABO and Rh blood types.

Gürer Giray, Burcu / Güven Açık, Gökçe

Journal of medical virology

2022 Volume 94, Issue 10, Page(s) 4776–4779

Abstract: Studies show that there may be a relationship between ABO blood type and SARS-CoV-2 transmission. It was aimed to determine by investigating the blood type of patients whose one-step reverse transcription and real-time polymerase chain reaction (RT-qPCR) ...

Abstract	Studies show that there may be a relationship between ABO blood type and SARS-CoV-2 transmission. It was aimed to determine by investigating the blood type of patients whose one-step reverse transcription and real-time polymerase chain reaction (RT-qPCR) test were positive for SARS-CoV-2. ABO and Rh blood types of individuals whose RT-qPCR test was positive for SARS-CoV-2 were examined and an evaluation was made to identify whether there was a relationship between them or not. The blood type data of 44.928 SARS-CoV-2 positive RT-qPCR test results have been obtained. 17.656 (39.29%) were delta, 8048 (17.91%) were alpha, 800 (1.78%) were beta, and 3000 (6.67%) were omicrons while 15.424 (34.33%) SARS-CoV-2 positive mutation was found to be negative. Our study suggests that O and Rh (-) blood types may provide protection against delta, AB and Rh (+) blood types may hinder omicron infection while A and Rh (+) blood types may be more vulnerable to alpha and delta while B and Rh (+) are more sensitive to beta mutation. The molecular mechanism underlying the relationship between blood types and SARS-CoV-2 infection needs further molecular studies and multi-centered studies.
MeSH term(s)	Blood Group Antigens ; COVID-19/diagnosis ; Humans ; Mutation ; Real-Time Polymerase Chain Reaction/methods ; SARS-CoV-2/genetics ; Sensitivity and Specificity
Chemical Substances	Blood Group Antigens
Language	English
Publishing date	2022-06-14
Publishing country	United States
Document type	Journal Article
ZDB-ID	752392-0
ISSN	1096-9071 ; 0146-6615
ISSN (online)	1096-9071
ISSN	0146-6615
DOI	10.1002/jmv.27923
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Article ; Online: Modifications in Class I and Class II Div. 1 malocclusion during orthodontic treatment and their association with TMD problems.

Giray, Bilgin / Sadry, Sanaz

Cranio : the journal of craniomandibular practice

2019 Volume 39, Issue 1, Page(s) 65–73

Abstract: ... ...

Abstract	Objective
MeSH term(s)	Dental Occlusion ; Humans ; Malocclusion ; Malocclusion, Angle Class II/therapy ; Orthodontics, Corrective ; Temporomandibular Joint Disorders
Language	English
Publishing date	2019-02-11
Publishing country	England
Document type	Journal Article
ZDB-ID	632570-1
ISSN	2151-0903 ; 0886-9634
ISSN (online)	2151-0903
ISSN	0886-9634
DOI	10.1080/08869634.2019.1572282
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Article ; Online: Effect of the coronavirus pandemic on tumor markers.

Purut, Yunus Emre / Giray, Burak / Gurbuz, Esra

Journal of medical virology

2021 Volume 93, Issue 9, Page(s) 5405–5408

Abstract: The new type of coronavirus could cause severe acute respiratory syndrome and injuries in other systems as well. Multiple organ damage can occur rapidly in patients infected with coronavirus disease 2019 (COVID-19). Previous studies have shown that many ... ...

Abstract	The new type of coronavirus could cause severe acute respiratory syndrome and injuries in other systems as well. Multiple organ damage can occur rapidly in patients infected with coronavirus disease 2019 (COVID-19). Previous studies have shown that many laboratory biomarkers were not within the normal ranges in COVID-19 patients. We aimed to summarize laboratory parameters and the tumor markers in COVID-19 patients. This is a retrospective cohort study conducted on 53 women between the ages of 19-85 years infected with COVID-19 at a training and research hospital between May 2020 and August 2020. Of the 53 women, 16 (30.2%) had leukopenia. The mean C-reactive protein level was 18.42 ± 59.33 mg/L. The mean procalcitonin level was 0.1 ± 0.21 µg/L. The liver function tests were within normal limits. The mean creatinine level was 0.58 ± 0.37 mg/dl. Elevated levels of α-fetoprotein (AFP) in 1 patient, elevated levels of carcinoembryonic antigen (CEA) in 2 patients, elevated levels of cancer antigen 125 (CA125) in 4 patients, elevated levels of CA19-9 in 2 patients, and elevated levels of CA15-3 in 2 patients were detected. One of 4 patients who were taken to the intensive care unit had elevated levels of AFP. In addition, 2 of 4 patients who were taken to the intensive care unit had elevated levels of CA125 and CA15-3. Except for AFP, levels of all tumor markers of the patient who died were high. We found that COVID-19 had no effect on tumor markers (CA125, CA19-9, CA15-3, AFP, and CEA).
MeSH term(s)	Adult ; Aged ; Aged, 80 and over ; Biomarkers, Tumor/blood ; C-Reactive Protein/metabolism ; CA-125 Antigen/blood ; CA-19-9 Antigen/blood ; COVID-19/blood ; COVID-19/diagnosis ; COVID-19/epidemiology ; COVID-19/virology ; Carcinoembryonic Antigen/blood ; Female ; Ferritins/blood ; Fibrin Fibrinogen Degradation Products/metabolism ; Humans ; Leukopenia/blood ; Leukopenia/diagnosis ; Leukopenia/virology ; Lymphocytes/virology ; Middle Aged ; Mucin-1/blood ; Neutrophils/virology ; Pandemics ; Procalcitonin/blood ; Retrospective Studies ; SARS-CoV-2/growth & development ; SARS-CoV-2/pathogenicity ; Troponin/blood ; Turkey/epidemiology ; alpha-Fetoproteins/metabolism
Chemical Substances	AFP protein, human ; Biomarkers, Tumor ; CA-125 Antigen ; CA-19-9 Antigen ; Carcinoembryonic Antigen ; Fibrin Fibrinogen Degradation Products ; MUC1 protein, human ; Mucin-1 ; Procalcitonin ; Troponin ; alpha-Fetoproteins ; fibrin fragment D ; C-Reactive Protein (9007-41-4) ; Ferritins (9007-73-2)
Language	English
Publishing date	2021-06-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	752392-0
ISSN	1096-9071 ; 0146-6615
ISSN (online)	1096-9071
ISSN	0146-6615
DOI	10.1002/jmv.27057
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Article ; Online: Determination of genetic diversity of multidrug-resistant

Gürer Giray, Burcu / Aslantürk, Ahmet / Şimşek, Hülya / Özgür, Didem / Kılıç, Selçuk / Aslan, Gönül

Pathogens and global health

2022 Volume 117, Issue 1, Page(s) 85–91

Abstract: Tuberculosis (TB) remains the leading cause of deaths from infectious disease worldwide. Nowadays, the tendency ... ...

Abstract	Tuberculosis (TB) remains the leading cause of deaths from infectious disease worldwide. Nowadays, the tendency of
MeSH term(s)	Humans ; Mycobacterium tuberculosis ; Phylogeny ; Minisatellite Repeats ; Turkey/epidemiology ; Genetic Variation ; Tuberculosis/epidemiology ; Tuberculosis, Multidrug-Resistant/epidemiology ; Genotype ; Bacterial Typing Techniques/methods
Language	English
Publishing date	2022-06-01
Publishing country	England
Document type	Journal Article
ZDB-ID	2625162-0
ISSN	2047-7732 ; 2047-7724
ISSN (online)	2047-7732
ISSN	2047-7724
DOI	10.1080/20477724.2022.2084807
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Article: Vaginal-assisted laparoscopic nerve sparing radical trachelectomy

Taşkıran, Cağatay / Mısırlıoğlu, Selim / Vatansever, Doğan / Giray, Burak / Arvas, Macit

Journal of the Turkish German Gynecological Association

2020 Volume 22, Issue 3, Page(s) 255–256

Abstract: Fertility-sparing surgery has gained popularity in the last three decades for the management of cervical cancer in women under 40 years of age. Radical trachelectomy is a fertility-sparing surgical technique for women who wish to retain their fertility. ... ...

Abstract	Fertility-sparing surgery has gained popularity in the last three decades for the management of cervical cancer in women under 40 years of age. Radical trachelectomy is a fertility-sparing surgical technique for women who wish to retain their fertility. Vaginal-assisted laparoscopic radical trachelectomy is feasible in selected patients with early cervical cancer. The aim of this video is to present a nerve-sparing vaginal-assisted laparoscopic radical trachelectomy demonstrating pelvic anatomical structures.
Language	English
Publishing date	2020-01-13
Publishing country	Turkey
Document type	Journal Article
ZDB-ID	2425806-4
ISSN	1309-0380 ; 1303-9695 ; 1309-0399
ISSN (online)	1309-0380 ; 1303-9695
ISSN	1309-0399
DOI	10.4274/jtgga.galenos.2019.2019.0121
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Article: Factors Affecting the Histopathological Outcomes of Atypical Glandular Cells on Pap Test.

Keles, Esra / Ozturk, Ugur K / Alınca, Cihat M / Giray, Burak / Kabaca, Canan / Cetiner, Handan

Journal of cytology

2021 Volume 38, Issue 4, Page(s) 210–215

Abstract: Background: Glandular cell abnormalities may indicate the presence of pre-malignant or malignant lesions.: Aim: This study aimed to investigate the relationship between atypical glandular cells (AGC) and patients' demographics, histopathological ... ...

Abstract	Background: Glandular cell abnormalities may indicate the presence of pre-malignant or malignant lesions. Aim: This study aimed to investigate the relationship between atypical glandular cells (AGC) and patients' demographics, histopathological outcomes, Human Papillomavirus (HPV) test results. Material and methods: Between January 2015 and December 2019, women with AGC on Pap tests were retrieved from the hospital electronic database. The patients with AGC on cervicovaginal smears who underwent further pathological, laboratory, and imaging diagnostic testing and who were followed up at least 1-year were included in the study, while those who had a history of cervical dysplasia or cancer, lost during follow-up, or had missing data were excluded. Results: Of 85,692 Pap smears, 114 (0.13%) were diagnosed with AGC, of those 88 cases were eligible for final analysis. Gynecological malignancies were detected in 13 (14.8%) patients; including 6 (6.8%) endometrioid endometrial cancers, 3 (3.4%) non-endometrioid endometrial cancers, 2 (2.3%) cervical adenocarcinomas, 1 (1.1%) cervical squamous cell carcinoma, and 1 (1.1%) high-grade tubal serous cancer. Multivariate analysis revealed that presence of concomitant abnormal squamous lesion ( Conclusion: The diagnosis of AGC may be related to the preneoplastic/neoplastic processes. A further comprehensive histopathological examination is required in women with AGC, aged 50 years and older, postmenopausal, HPV-positivity and concomitant squamous cell abnormality Clinicians should consider ovarian pathologies when there is no pathological finding on endometrial or cervical histopathological examination.
Language	English
Publishing date	2021-11-12
Publishing country	India
Document type	Journal Article
ZDB-ID	645018-0
ISSN	0970-9371
ISSN	0970-9371
DOI	10.4103/JOC.JOC_54_21
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Article ; Online: Effect of Human Papillomavirus Subtype on the Rate of Positive Surgical Margin After Cervical Conization.

Purut, Yunus Emre / Giray, Burak / Akis, Serkan / Peker, Esra Keles / Babayeva, Gulchin / Kabaca, Canan / Api, Murat

International journal of surgical pathology

2022 Volume 31, Issue 1, Page(s) 20–25

Abstract: Objective. ...

Abstract	Objective.
MeSH term(s)	Pregnancy ; Female ; Humans ; Human Papillomavirus Viruses ; Margins of Excision ; Papillomavirus Infections/complications ; Papillomavirus Infections/surgery ; Retrospective Studies ; Conization ; Human papillomavirus 16/genetics ; Human papillomavirus 18 ; Neoplasm Recurrence, Local/pathology ; Uterine Cervical Neoplasms/pathology ; Papillomaviridae
Language	English
Publishing date	2022-12-13
Publishing country	United States
Document type	Journal Article
ZDB-ID	1336393-1
ISSN	1940-2465 ; 1066-8969
ISSN (online)	1940-2465
ISSN	1066-8969
DOI	10.1177/10668969221143460
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Article ; Online: Post-conization follow-up of patients with CIN 2/3 with different amount of distance to negative cone biopsy margin: a retrospective cohort study.

Giray, Burak / Kabaca-Kocakusak, Canan / Guray-Uzun, Mine / Akis, Serkan

Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

2019 Volume 40, Issue 3, Page(s) 406–410

Abstract: The aim of this study was to investigate whether patients with CIN 2/3 with different amount of distance to negative cone biopsy margin differ in terms of post-conization follow-up results. Cold-knife cone specimens with a negative surgical margin with a ...

Abstract	The aim of this study was to investigate whether patients with CIN 2/3 with different amount of distance to negative cone biopsy margin differ in terms of post-conization follow-up results. Cold-knife cone specimens with a negative surgical margin with a diagnosis of CIN-2/3 were selected. The minimum distance between the margin and lesion was categorised as less than 2 mm (Group-1), 2-5 mm (Group-2), or more than 5 mm (Group-3). There were no statistically significant differences between groups in terms of postoperative cone-biopsy results (
MeSH term(s)	Adult ; Biopsy/methods ; Biopsy/statistics & numerical data ; Cervical Intraepithelial Neoplasia/pathology ; Cervical Intraepithelial Neoplasia/surgery ; Cervix Uteri/pathology ; Conization/methods ; Conization/statistics & numerical data ; Female ; Follow-Up Studies ; Humans ; Margins of Excision ; Middle Aged ; Neoplasm Staging ; Retrospective Studies ; Treatment Outcome ; Uterine Cervical Neoplasms/pathology ; Uterine Cervical Neoplasms/surgery
Language	English
Publishing date	2019-08-28
Publishing country	England
Document type	Journal Article
ZDB-ID	604639-3
ISSN	1364-6893 ; 0144-3615
ISSN (online)	1364-6893
ISSN	0144-3615
DOI	10.1080/01443615.2019.1633517
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