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  1. Article ; Online: Inclusion of child-relevant data in the development and validation of heat vulnerability indices: a commentary.

    Weinberger, Kate R / Girma, Blean / Clougherty, Jane E / Sheffield, Perry E

    Environmental research, health : ERH

    2023  Volume 1, Issue 3, Page(s) 33001

    Language English
    Publishing date 2023-06-22
    Publishing country England
    Document type Journal Article
    ISSN 2752-5309
    ISSN (online) 2752-5309
    DOI 10.1088/2752-5309/acdd8a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: High ambient temperatures associations with children and young adult injury emergency department visits in NYC.

    Girma, Blean / Liu, Bian / Schinasi, Leah H / Clougherty, Jane E / Sheffield, Perry E

    Environmental research, health : ERH

    2023  Volume 1, Issue 3, Page(s) 35004

    Abstract: Injury is a significant health burden for children and young adult and may be an increasing concern in a warming climate. Research reveals many impacts to children's health associated with hot weather and heatwave events, including a growing literature ... ...

    Abstract Injury is a significant health burden for children and young adult and may be an increasing concern in a warming climate. Research reveals many impacts to children's health associated with hot weather and heatwave events, including a growing literature on the association between high ambient temperature and injury, which may vary by intent such as injury resulting from violence. However, little is known about how this association varies across different types of injury and subgroups of young people. We examined relationships between warm season ambient temperature and intentional and unintentional injury among children and young adults in New York City (NYC). Within a case-crossover design, our study observed injury-related emergency department (ED) visits from the New York Statewide Planning and Research Cooperative System administrative dataset. Injuries were categorized as unintentional or intentional injuries during the warm season (May through September) in NYC from 2005 to 2011 among patients (0, 1-4, 5-9, 10-14, 15-19, 20-25 years old (y.o.)). Conditional logistic regression models with distributed lag non-linear functions were used to model the cumulative odds ratio (OR) injury-related ED visit over 0-5 lag days. Analyses were stratified by age group and sex to understand how associations vary across young people of different age and sex. There were a total of 572 535 injury-related ED visits. The largest effect of elevated temperature (daily minimum 77°F vs 48°F) was for unintentional injury among 5-9 y.o. (OR 1.32, 95% CI 1.23, 1.42) and for intentional injury among 20-25 y.o. (OR 1.54, 95% CI 1.28, 1.85). Further stratified analyses revealed that the highest risk of unintentional injury was among 5-9 y.o. males and 20-25 y.o. males for intentional injury. Our results suggest that high ambient temperatures are associated with higher odds of unintentional and intentional injuries among children. This work adds to a growing body of literature demonstrating the adverse impacts of heat on children, and suggests the need for messaging to parents and children about adopting adaptive strategies to prevent injuries when it is hot outside.
    Language English
    Publishing date 2023-07-12
    Publishing country England
    Document type Journal Article
    ISSN 2752-5309
    ISSN (online) 2752-5309
    DOI 10.1088/2752-5309/ace27b
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Temperature and mental health-related emergency department and hospital encounters among children, adolescents and young adults.

    Niu, Li / Girma, Blean / Liu, Bian / Schinasi, Leah H / Clougherty, Jane E / Sheffield, Perry

    Epidemiology and psychiatric sciences

    2023  Volume 32, Page(s) e22

    Abstract: Aims: We examine the association between high ambient temperature and acute mental health-related healthcare encounters in New York City for children, adolescents and young adults.: Methods: This case-crossover study included emergency department (ED) ...

    Abstract Aims: We examine the association between high ambient temperature and acute mental health-related healthcare encounters in New York City for children, adolescents and young adults.
    Methods: This case-crossover study included emergency department (ED) visits and hospital encounters with a primary diagnosis of any mental health disorder during warm-season months (June-August) in New York City from 2005 to 2011 from patients of three age groups (6-11, 12-17 and 18-25 years). Using a distributed lag non-linear model over 0-5 lag days, by fitting a conditional logistic regression for each age group, we calculated the cumulative odds ratios of mental health encounters associated with an elevated temperature. Analyses were stratified by race/ethnicity, payment source and mental health categories to elucidate vulnerable subpopulations.
    Results: In New York City, there were 82,982 mental health-related encounters for young people aged 6 to 25 years during our study period months. Elevated temperature days were associated with higher risk of mental health-related ED and hospital encounters for the 6- to 11-year-olds (odds ratio [OR]: 1.28, 95% confidence interval [CI]: 1.13-1.46), for the 12- to 17-year-olds (OR: 1.17, 95% CI: 1.09-1.25) and for the 18- to 25-year-olds (OR: 1.09, 95% CI: 1.04-1.15). Children with reaction disorders, adolescents with anxiety and bipolar disorders, young adults with psychosis and reaction disorders and Black and non-Hispanic children and adolescents showed vulnerability to elevated temperature.
    Conclusions: We found that elevated ambient temperatures were associated with acute mental health ED or hospital encounters across childhood, adolescence and young adulthood.
    MeSH term(s) Adolescent ; Adult ; Child ; Humans ; Young Adult ; Cross-Over Studies ; Emergency Service, Hospital ; Hospitals ; Mental Health ; Temperature ; Weather ; New York City/epidemiology ; Mental Disorders/epidemiology
    Language English
    Publishing date 2023-04-17
    Publishing country England
    Document type Journal Article
    ZDB-ID 2607964-1
    ISSN 2045-7979 ; 2045-7960
    ISSN (online) 2045-7979
    ISSN 2045-7960
    DOI 10.1017/S2045796023000161
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pregnancy and newborn health - heat impacts and emerging solutions.

    Bekkar, Bruce / DeNicola, Nathaniel / Girma, Blean / Potarazu, Savita / Sheffield, Perry

    Seminars in perinatology

    2023  Volume 47, Issue 8, Page(s) 151837

    Abstract: Evidence is accumulating, both in the US and abroad, of the apparent serious health impacts of various environmental exposures tied to climate change. High ambient temperature, or heat, is a worsening global health risk. Heat risk is affected by many ... ...

    Abstract Evidence is accumulating, both in the US and abroad, of the apparent serious health impacts of various environmental exposures tied to climate change. High ambient temperature, or heat, is a worsening global health risk. Heat risk is affected by many factors such as the magnitude, duration, and timing of exposure - such as specific, critical windows during pregnancy. This article focuses on the association of heat with both adverse pregnancy and newborn health outcomes. Regarding pregnancy, studies link heat and preterm birth, low birth weight and stillbirth. Multiple potential mechanisms support the biological plausibility of these associations. Emerging evidence suggests that heat, via epigenetics, may affect maternal health far beyond pregnancy. For newborn health impacts, heat is associated with increased hospitalization, neurologic and gastrointestinal dysfunction, and infant death. Research gaps include the need to study neonates separately from children and determining the mechanisms linking heat to adverse outcomes. We also highlight disparate adverse reproductive health outcomes for communities of color and low income tied to disproportionate exposures to environmental stressors like heat. Finally, we summarize educational and clinical tool resources for clinicians, information for patients, and opportunities for near-term action using the precautionary principle framework.
    MeSH term(s) Pregnancy ; Child ; Female ; Infant, Newborn ; Humans ; Hot Temperature ; Premature Birth ; Infant Health ; Stillbirth ; Infant, Low Birth Weight
    Language English
    Publishing date 2023-10-10
    Publishing country United States
    Document type Journal Article
    ZDB-ID 752403-1
    ISSN 1558-075X ; 0146-0005
    ISSN (online) 1558-075X
    ISSN 0146-0005
    DOI 10.1016/j.semperi.2023.151837
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Cancer Diagnosis and Prognosis After Guillain-Barré Syndrome: A Population-Based Cohort Study.

    Girma, Blean / Farkas, Dóra Körmendiné / Laugesen, Kristina / Skajaa, Nils / Henderson, Victor W / Boffetta, Paolo / Sørensen, Henrik Toft

    Clinical epidemiology

    2022  Volume 14, Page(s) 871–878

    Abstract: Introduction: It is unclear whether Guillain-Barré syndrome (GBS) can be a marker of a paraneoplastic syndrome. We examined whether GBS is associated with cancer and whether the prognosis of GBS patients with cancer differs from that of other cancer ... ...

    Abstract Introduction: It is unclear whether Guillain-Barré syndrome (GBS) can be a marker of a paraneoplastic syndrome. We examined whether GBS is associated with cancer and whether the prognosis of GBS patients with cancer differs from that of other cancer patients.
    Materials and methods: We conducted a population-based cohort study of patients diagnosed with GBS between 1978 and 2017 using Danish registry-data. Main outcome measures were cancer incidence and mortality after cancer diagnosis. We calculated absolute risks of a cancer diagnosis, treating death as competing risk, and standardized incidence ratios (SIRs) as measures of relative risk. We matched each GBS cancer patient with up to 10 cancer patients without a GBS diagnosis and examined the six-month survival after cancer diagnosis using Cox regression analysis.
    Results: We identified 7897 patients (58% male, median age 57 years) with GBS. During a median follow-up of 9.5 years, the one-year risk of cancer was 2.7% (95% confidence interval (CI), 2.4-3.1). The SIR was increased throughout follow-up, but most noticeably during the first year after diagnosis (SIR: 3.35, 2.92-3.83). SIRs were particularly elevated for hematologic cancers (SIR: 8.67, 6.49-11.34), smoking-related cancers (SIR: 3.57, 2.81-4.47), and cancers of neurological origin (SIR: 8.60, 5.01-13.77). Lung cancer was the main contributor to the overall excess risk, which persisted after 36 months of follow-up (SIR: 1.17, 1.09-1.25). The mortality rate ratio comparing patients diagnosed with any cancer within one year of their GBS diagnosis and matched GBS-free cancer cohort members was 1.56 (95% CI, 1.27-1.90).
    Conclusion: GBS patients had a three-fold increased risk of cancer diagnosis in the first year of follow-up. The absolute cancer risk was almost 3.0%. A GBS diagnosis was an adverse prognostic marker for survival following cancer diagnosis. Clinicians should consider occult cancer in patients hospitalized with GBS.
    Language English
    Publishing date 2022-07-19
    Publishing country New Zealand
    Document type Journal Article
    ZDB-ID 2494772-6
    ISSN 1179-1349
    ISSN 1179-1349
    DOI 10.2147/CLEP.S369908
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Chronic Conditions and Pediatric Healthcare Utilization during Warm Weather Days in New York City.

    Niu, Li / Herrera, Maria Teresa / Girma, Blean / Liu, Bian / Glassberg, Jeffrey / Schinasi, Leah / Clougherty, Jane E / Sheffield, Perry

    The journal of applied research on children : informing policy for children at risk

    2022  Volume 12, Issue 1

    Language English
    Publishing date 2022-04-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2657730-6
    ISSN 2155-5834
    ISSN 2155-5834
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: High ambient temperature and child emergency and hospital visits in New York City.

    Niu, Li / Herrera, Maria Teresa / Girma, Blean / Liu, Bian / Schinasi, Leah / Clougherty, Jane E / Sheffield, Perry E

    Paediatric and perinatal epidemiology

    2021  Volume 36, Issue 1, Page(s) 36–44

    Abstract: Background: Emerging literature has documented heat-related impacts on child health, yet few studies have evaluated the effects of heat among children of different age groups and comparing emergency department (ED) and hospitalisation risks.: ... ...

    Abstract Background: Emerging literature has documented heat-related impacts on child health, yet few studies have evaluated the effects of heat among children of different age groups and comparing emergency department (ED) and hospitalisation risks.
    Objectives: To examine the differing associations between high ambient temperatures and risk of ED visits and hospitalisations among children by age group in New York City (NYC).
    Methods: We used New York Statewide Planning and Research Cooperative System (SPARCS) data on children aged 0-18 years admitted to NYC EDs (n = 2,252,550) and hospitals (n = 228,006) during the warm months (May-September) between 2005 and 2011. Using a time-stratified, case-crossover design, we estimated the risk of ED visits and hospitalisations associated with daily maximum temperature (Tmax) for children of all ages and by age group.
    Results: The average Tmax over the study period was 80.3°F (range 50°, 104°F). Tmax conferred the greatest risk of ED visits for children aged 0-4, with a 6-day cumulative excess risk of 2.4% (95% confidence interval [CI] 1.7, 3.0) per 13°F (ie interquartile range) increase in temperature. Children and adolescents 5-12 years (0.8%, 95% CI 0.1, 1.6) and 13-18 years (1.4%, 95% CI 0.6, 2.3) are also sensitive to heat. For hospitalisations, only adolescents 13-18 years had increased heat-related risk, with a cumulative excess risk of 7.9% (95% CI 2.0, 14.2) per 13°F increase in Tmax over 85°F.
    Conclusions: This urban study in NYC reinforces that young children are particularly vulnerable to effects of heat, but also demonstrates the sensitivity of older children and adolescents as well. These findings underscore the importance of focussing on children and adolescents in targeting heat illness prevention and emergency response activities, especially as global temperatures continue to rise.
    MeSH term(s) Adolescent ; Child ; Child, Preschool ; Emergency Service, Hospital ; Hospitals ; Hot Temperature ; Humans ; New York City/epidemiology ; Temperature
    Language English
    Publishing date 2021-06-23
    Publishing country England
    Document type Journal Article
    ZDB-ID 639089-4
    ISSN 1365-3016 ; 0269-5022 ; 1353-663X
    ISSN (online) 1365-3016
    ISSN 0269-5022 ; 1353-663X
    DOI 10.1111/ppe.12793
    Database MEDical Literature Analysis and Retrieval System OnLINE

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