LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 152

Search options

  1. Article: Extradural hemorrhagic spinal cavernous angioma in a paucisymptomatic child: A rare case with review of the current literature.

    Scafa, Anthony Kevin / Giugliano, Marco / Gallo, Marco / Piccirilli, Manolo

    Surgical neurology international

    2022  Volume 13, Page(s) 123

    Abstract: Background: Cavernous angiomas, also referred to as cavernous hemangiomas or cavernomas (CMs), are vascular malformative benign neoplasms that may develop in any part of the central nervous system. Spinal CMs are uncommon (overall incidence rate of 0.04- ...

    Abstract Background: Cavernous angiomas, also referred to as cavernous hemangiomas or cavernomas (CMs), are vascular malformative benign neoplasms that may develop in any part of the central nervous system. Spinal CMs are uncommon (overall incidence rate of 0.04-0.05%). Pure epidural CMs account for 1-2% of all spinal CMs and 4% of all spinal epidural tumors. Diagnosis is extremely rare in the pediatric age. To the best of our knowledge, only 10 cases have been described so far. The treatment of choice is microsurgical resection.
    Case description: We describe here the rare case of a cervicothoracic hemorrhagic spinal epidural cavernoma in a paucisymptomatic, 8-year-old female Bangladeshi child. C7-T2 laminectomy with excision of a scarcely defined, capsulated dark red lesion was performed with good recovery.
    Conclusion: Spinal epidural cavernomas are rare. Childhood presentation is even rarer. The reason could be found in a greater "compliance" and to a rarer occurrence of acute bleeding in children, thus resulting in a delayed diagnosis. Surgical excision is the gold standard of treatment.
    Language English
    Publishing date 2022-03-31
    Publishing country United States
    Document type Case Reports
    ISSN 2229-5097
    ISSN 2229-5097
    DOI 10.25259/SNI_997_2021
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  2. Article ; Online: The dynamic sagittal balance: Definition of dynamic spino-pelvic parameters using a method based on gait analysis.

    Miscusi, M / Di Bartolomeo, A / Scafa, A / Ricciardi, L / Chiarella, V / Giugliano, M / Castiglia, S F / Varrecchia, T / Serrao, M / Raco, A

    World neurosurgery: X

    2023  Volume 18, Page(s) 100165

    Abstract: Introduction: Evaluation of sagittal balance parameters is a standard assessment before spine surgery. However, these parameters can change during walking. We aimed to describe the behavior of spino-pelvic parameters during walking in healthy subjects.!# ...

    Abstract Introduction: Evaluation of sagittal balance parameters is a standard assessment before spine surgery. However, these parameters can change during walking. We aimed to describe the behavior of spino-pelvic parameters during walking in healthy subjects.
    Material and methods: Analyses were performed in 60 healthy subjects.
    Results: PTA-cycle, PTA-stance, PTA-swing, STS-cycle, STS-stance, and STS-swing showed good-to-excellent internal reliability (ICC = 0.867; ICC = 0.700; ICC = 0.817, respectively). The parameters with the lowest variability were radiographic PI (CV = 16.53%), PTA-stance (CV = 9.55%), and PTA-swing (CV = 17.22%). PT was directly related to PTA-cycle (r = 0.534, p = .027). PI was inversely correlated with trunk flexo-extension range of motion (r = -0.654, p = .004) and dynamic PT (r = -0.489, p = .047). LL and SS were directly related to knee flexo-extension (r = 0.505, p = .039; r = 0.493, p = .045, respectively). SVA was correlated with the trunk obliquity in dynamics (r = 0.529, p = .029). PTA-cycle was directly related to trunk obliquity (r = 0.538, p = .049). STS and TA in the three phases of step were related to the kinematic parameters of the pelvis. TA was related to flexo-extension of the hip and knee.
    Conclusions: Variations of dynamic spino-pelvic parameters occur during walking and modify sagittal balance from a static to a dynamic condition.
    Language English
    Publishing date 2023-02-02
    Publishing country United States
    Document type Journal Article
    ISSN 2590-1397
    ISSN (online) 2590-1397
    DOI 10.1016/j.wnsx.2023.100165
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  3. Article ; Online: Foetal neural progenitors contribute to postnatal circuits formation ex vivo: an electrophysiological investigation.

    Manzati, Matteo / Sorbo, Teresa / Giugliano, Michele / Ballerini, Laura

    Molecular brain

    2020  Volume 13, Issue 1, Page(s) 78

    Abstract: Neuronal progenitor cells (NPC) play an essential role in homeostasis of the central nervous system (CNS). Considering their ability to differentiate into specific lineages, their manipulation and control could have a major therapeutic impact for those ... ...

    Abstract Neuronal progenitor cells (NPC) play an essential role in homeostasis of the central nervous system (CNS). Considering their ability to differentiate into specific lineages, their manipulation and control could have a major therapeutic impact for those CNS injuries or degenerative diseases characterized by neuronal cell loss. In this work, we established an in vitro co-culture and tested the ability of foetal NPC (fNPC) to integrate among post-mitotic hippocampal neurons and contribute to the electrical activity of the resulting networks. We performed extracellular electrophysiological recordings of the activity of neuronal networks and compared the properties of spontaneous spiking in hippocampal control cultures (HCC), fNPC, and mixed circuitries ex vivo. We further employed patch-clamp intracellular recordings to examine single-cell excitability. We report of the capability of fNPC to mature when combined to hippocampal neurons, shaping the profile of network activity, a result suggestive of newly formed connectivity ex vivo.
    MeSH term(s) Action Potentials/physiology ; Animals ; Cells, Cultured ; Coculture Techniques ; Electrophysiological Phenomena/physiology ; Hippocampus/cytology ; Hippocampus/physiology ; Nerve Net/physiology ; Neurogenesis ; Neurons/cytology ; Neurons/physiology ; Patch-Clamp Techniques ; Rats ; Rats, Wistar ; Single-Cell Analysis
    Language English
    Publishing date 2020-05-19
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2436057-0
    ISSN 1756-6606 ; 1756-6606
    ISSN (online) 1756-6606
    ISSN 1756-6606
    DOI 10.1186/s13041-020-00619-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Rapid spontaneous resolution of lumbar ganglion cysts: A case report.

    Chiarella, Vito / Ramieri, Alessandro / Giugliano, Marco / Domenicucci, Maurizio

    World journal of orthopedics

    2020  Volume 11, Issue 1, Page(s) 68–75

    Abstract: Background: To discuss the rare event of spontaneous resolution of a lumbar ganglion cyst, a personal case report and 25 cases culled from the literature were described in detail. We focused on demographic, classification, clinical and radiological ... ...

    Abstract Background: To discuss the rare event of spontaneous resolution of a lumbar ganglion cyst, a personal case report and 25 cases culled from the literature were described in detail. We focused on demographic, classification, clinical and radiological findings, treatment, outcome and radiological resolution.
    Case summary: A 51-year-old man presented to our observation with complaints of low back and right leg pain. Lumbar magnetic resonance imaging (MRI). showed a L4-L5 ganglion cyst. The patient was referred to medical therapy and bracing. After 4 wk, he showed a complete resolution of pain. The complete spontaneous resolution of the cyst was demonstrated by the followed-up MRI.
    Conclusion: Spontaneous resolution of lumbar ganglion is very rare and only 26 cases, including ours, were reported in literature. Different degrees of biomechanical impairment seem to play a fundamental role in the pathogenesis. Related symptoms are essentially represented by low back and/or radicular pain, without significant neurological disorders. Anti-inflammatory drugs, light unloading exercises and brace could be recommended to administrated pain and decrease facet loads. Mean time for clinical improvement was 7 mo, while MRI disappearance occurred in an average time of 11 mo. Therefore, surgery should be applied when conservative treatment, prolonged at least 6 mo, fails.
    Language English
    Publishing date 2020-01-18
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2649712-8
    ISSN 2218-5836
    ISSN 2218-5836
    DOI 10.5312/wjo.v11.i1.68
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: Homogeneous and Narrow Bandwidth of Spike Initiation in Rat L1 Cortical Interneurons.

    Borda Bossana, Stefano / Verbist, Christophe / Giugliano, Michele

    Frontiers in cellular neuroscience

    2020  Volume 14, Page(s) 118

    Abstract: The cortical layer 1 (L1) contains a population of GABAergic interneurons, considered a key component of information integration, processing, and relaying in neocortical networks. In fact, L1 interneurons combine top-down information with feed-forward ... ...

    Abstract The cortical layer 1 (L1) contains a population of GABAergic interneurons, considered a key component of information integration, processing, and relaying in neocortical networks. In fact, L1 interneurons combine top-down information with feed-forward sensory inputs in layer 2/3 and 5 pyramidal cells (PCs), while filtering their incoming signals. Despite the importance of L1 for network emerging phenomena, little is known on the dynamics of the spike initiation and the encoding properties of its neurons. Using acute brain tissue slices from the rat neocortex, combined with the analysis of an existing database of model neurons, we investigated the dynamical transfer properties of these cells by sampling an entire population of known "electrical classes" and comparing experiments and model predictions. We found the bandwidth of spike initiation to be significantly narrower than in L2/3 and 5 PCs, with values below 100 cycle/s, but without significant heterogeneity in the cell response properties across distinct electrical types. The upper limit of the neuronal bandwidth was significantly correlated to the mean firing rate, as anticipated from theoretical studies but not reported for PCs. At high spectral frequencies, the magnitude of the neuronal response attenuated as a power-law, with an exponent significantly smaller than what was reported for pyramidal neurons and reminiscent of the dynamics of a "leaky" integrate-and-fire model of spike initiation. Finally, most of our
    Language English
    Publishing date 2020-06-17
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2452963-1
    ISSN 1662-5102
    ISSN 1662-5102
    DOI 10.3389/fncel.2020.00118
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Article ; Online: Carbon catabolite repression occurrence in photo fermentation of ethanol-rich substrates.

    Policastro, Grazia / Giugliano, Marco / Luongo, Vincenzo / Napolitano, Raffaele / Fabbricino, Massimiliano

    Journal of environmental management

    2021  Volume 297, Page(s) 113371

    Abstract: The paper investigates the phenomenon of Carbon Catabolite Repression occurring during photo fermentation of ethanol-rich effluents, which usually contain ethanol as main carbon source, and glycerol as secondary one. The study was conducted using mixed ... ...

    Abstract The paper investigates the phenomenon of Carbon Catabolite Repression occurring during photo fermentation of ethanol-rich effluents, which usually contain ethanol as main carbon source, and glycerol as secondary one. The study was conducted using mixed phototrophic cultures, adopting, as substrate, the effluent produced by the alcoholic fermentation of sugar cane bagasse. In order to elucidate the phenomenon, experimental tests were carried out using two different ethanol to glycerol ratios. Results were compared with those resulting from pure ethanol and glycerol conversion. According to the obtained data, as a result of Carbon Catabolite Repression occurrence, the presence of glycerol negatively affects hydrogen production. Indeed, part of the ethanol source is converted to biomass and polyhydroxybutyrate rather than to hydrogen. In more details, the presence of glycerol determines a drop of the hydrogen production, which goes from 12 % to 32 %, according to the ethanol/glycerol ratio, compared to the production obtained from fermentation of ethanol alone. Therefore, to promote the hydrogen production, it is advisable to apply strategies to produce low glycerol concentrations in the ethanol production stage.
    MeSH term(s) Catabolite Repression ; Ethanol ; Fermentation ; Glycerol ; Hydrogen
    Chemical Substances Ethanol (3K9958V90M) ; Hydrogen (7YNJ3PO35Z) ; Glycerol (PDC6A3C0OX)
    Language English
    Publishing date 2021-07-26
    Publishing country England
    Document type Journal Article
    ZDB-ID 184882-3
    ISSN 1095-8630 ; 0301-4797
    ISSN (online) 1095-8630
    ISSN 0301-4797
    DOI 10.1016/j.jenvman.2021.113371
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 7556: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article ; Online: Multidimensional Functional Profiling of Human Neuropathogenic

    Frisari, Simone / Santo, Manuela / Hosseini, Ali / Manzati, Matteo / Giugliano, Michele / Mallamaci, Antonello

    International journal of molecular sciences

    2022  Volume 23, Issue 3

    Abstract: ... ...

    Abstract FOXG1
    MeSH term(s) Alleles ; Animals ; Brain/metabolism ; Cerebral Cortex/metabolism ; Forkhead Transcription Factors/genetics ; Forkhead Transcription Factors/metabolism ; Gene Expression/genetics ; Gene Expression Regulation, Developmental/genetics ; Gene Frequency/genetics ; Humans ; Mice ; Nerve Tissue Proteins/genetics ; Nerve Tissue Proteins/metabolism ; Neurodevelopmental Disorders/genetics ; Neurogenesis ; Neurons/metabolism ; Primary Cell Culture ; Proof of Concept Study
    Chemical Substances FOXG1 protein, human ; Forkhead Transcription Factors ; Foxg1 protein, mouse ; Nerve Tissue Proteins
    Language English
    Publishing date 2022-01-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms23031343
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  8. Article ; Online: Calcium waves in astrocyte networks: theory and experiments.

    Giugliano, Michele

    Frontiers in neuroscience

    2009  Volume 3, Issue 2, Page(s) 160–161

    Language English
    Publishing date 2009-09-15
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2411902-7
    ISSN 1662-453X ; 1662-4548
    ISSN (online) 1662-453X
    ISSN 1662-4548
    DOI 10.3389/neuro.01.019.2009
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  9. Article: Dual effects of

    Nieto-Estevez, Vanesa / Varma, Parul / Mirsadeghi, Sara / Caballero, Jimena / Gamero-Alameda, Sergio / Hosseini, Ali / Goswami, Sonal / Silvosa, Marc J / Thodeson, Drew M / Lybrand, Zane R / Giugliano, Michele / Navara, Christopher / Hsieh, Jenny

    bioRxiv : the preprint server for biology

    2024  

    Abstract: Mutations ... ...

    Abstract Mutations in
    Language English
    Publishing date 2024-01-25
    Publishing country United States
    Document type Preprint
    DOI 10.1101/2024.01.25.577271
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  10. Article: Synthesis of generalized algorithms for the fast computation of synaptic conductances with Markov kinetic models in large network simulations.

    Giugliano, M

    Neural computation

    2000  Volume 12, Issue 4, Page(s) 903–931

    Abstract: Markovkinetic models constitute a powerful framework to analyze patch-clamp data from single-channel recordings and model the dynamics of ion conductances and synaptic transmission between neurons. In particular, the accurate simulation of a large number ...

    Abstract Markovkinetic models constitute a powerful framework to analyze patch-clamp data from single-channel recordings and model the dynamics of ion conductances and synaptic transmission between neurons. In particular, the accurate simulation of a large number of synaptic inputs in wide-scale network models may result in a computationally highly demanding process. We present a generalized consolidating algorithm to simulate efficiently a large number of synaptic inputs of the same kind (excitatory or inhibitory), converging on an isopotential compartment, independently modeling each synaptic current by a generic n-state Markov model characterized by piece-wise constant transition probabilities. We extend our findings to a class of simplified phenomenological descriptions of synaptic transmission that incorporate higher-order dynamics, such as short-term facilitation, depression, and synaptic plasticity.
    MeSH term(s) Algorithms ; Computer Simulation ; Markov Chains ; Neural Conduction/physiology ; Neural Networks (Computer) ; Neuronal Plasticity/physiology ; Synapses/physiology
    Language English
    Publishing date 2000-04
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1025692-1
    ISSN 1530-888X ; 0899-7667
    ISSN (online) 1530-888X
    ISSN 0899-7667
    DOI 10.1162/089976600300015646
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 2914: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top