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  1. Book ; Online: Earth Observation Data Cubes

    Giuliani, Gregory / Camara, Gilberto / Killough, Brian / Minchin, Stuart

    2020  

    Abstract: Satellite Earth observation (EO) data have already exceeded the petabyte scale and are increasingly freely and openly available from different data providers. This poses a number of issues in terms of volume (e.g., data volumes have increased ... ...

    Abstract Satellite Earth observation (EO) data have already exceeded the petabyte scale and are increasingly freely and openly available from different data providers. This poses a number of issues in terms of volume (e.g., data volumes have increased 10
    Keywords Science (General) ; Geography (General)
    Size 1 electronic resource (302 pages)
    Publisher MDPI - Multidisciplinary Digital Publishing Institute
    Document type Book ; Online
    Note English ; Open Access
    HBZ-ID HT020480944
    ISBN 9783039280926 ; 9783039280933 ; 3039280929 ; 3039280937
    DOI 10.3390/books978-3-03928-093-3
    Database ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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  2. Article ; Online: Ketone bodies in cell physiology and cancer.

    Giuliani, Giacomo / Longo, Valter D

    American journal of physiology. Cell physiology

    2024  Volume 326, Issue 3, Page(s) C948–C963

    Abstract: Ketogenic diets (KDs), fasting, or prolonged physical activity elevate serum ketone bodies (KBs) levels, providing an alternative fuel source for the brain and other organs. However, KBs play pleiotropic roles that go beyond their role in energy ... ...

    Abstract Ketogenic diets (KDs), fasting, or prolonged physical activity elevate serum ketone bodies (KBs) levels, providing an alternative fuel source for the brain and other organs. However, KBs play pleiotropic roles that go beyond their role in energy production. KBs can act as signaling metabolites, influence gene expression, proteins' posttranslational modifications (PTMs), inflammation, and oxidative stress. Here, we explore the impact of KBs on mammalian cell physiology, including aging and tissue regeneration. We also concentrate on KBs and cancer, given the extensive evidence that dietary approaches inducing ketosis, including fasting-mimicking diets (FMDs) and KDs, can prevent cancer and affect tumor progression.
    MeSH term(s) Animals ; Humans ; Ketone Bodies/metabolism ; Ketone Bodies/pharmacology ; Neoplasms/metabolism ; Brain/metabolism ; Oxidative Stress ; Cell Physiological Phenomena ; Mammals/metabolism
    Chemical Substances Ketone Bodies
    Language English
    Publishing date 2024-01-08
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 392098-7
    ISSN 1522-1563 ; 0363-6143
    ISSN (online) 1522-1563
    ISSN 0363-6143
    DOI 10.1152/ajpcell.00441.2023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Artisanal and Small-Scale Mining Sites in the Democratic Republic of the Congo Are Not Associated with Nighttime Light Emissions

    Kyba, Christopher / Giuliani, Gregory / Tockner, Klement / LACROIX, Pierre

    J, 2(2):152-161

    2019  

    Abstract: Maintaining records of artisanal and small-scale mining sites in developing countries requires considerable effort, so it would be beneficial if Earth observation data from space could assist in the identifying and monitoring of such sites. Artificial ... ...

    Institution Leibniz-Institut für Gewässerökologie und Binnenfischerei
    Abstract Maintaining records of artisanal and small-scale mining sites in developing countries requires considerable effort, so it would be beneficial if Earth observation data from space could assist in the identifying and monitoring of such sites. Artificial light emissions are common at industrial-scale mining sites and have been associated with small-scale illegal mining in some contexts. Here, we examine whether known artisanal and small-scale mining sites in the Democratic Republic of the Congo (DRC) are associated with observations of night light emissions by the Visible Infrared Imaging Radiometer Suite Day/Night Band (DNB). Light emissions from the mining sites were not observed: the radiance observed from the sites was near zero and nearly identical to that observed for a set of randomly-chosen locations in the same region. While it is the case that DNB night lights’ products provide useful data in other resource extraction contexts, they do not appear to be useful for identifying artisanal mining sites in the DRC.
    Keywords Democratic Republic of the Congo ; VIIRS DNB ; artisanal mining ; night lights ; remote sensing
    Language English
    Document type Article
    Database Repository for Life Sciences

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  4. Article ; Online: Impact of the COVID-19 pandemic on multidrug-resistant hospital-acquired bacterial infections.

    Bongiovanni, M / Barilaro, G / Zanini, U / Giuliani, G

    The Journal of hospital infection

    2022  Volume 123, Page(s) 191–192

    MeSH term(s) Anti-Bacterial Agents/therapeutic use ; Bacterial Infections/microbiology ; COVID-19 ; Drug Resistance, Multiple, Bacterial ; Hospitals ; Humans ; Pandemics/prevention & control
    Chemical Substances Anti-Bacterial Agents
    Language English
    Publishing date 2022-03-01
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 779366-2
    ISSN 1532-2939 ; 0195-6701
    ISSN (online) 1532-2939
    ISSN 0195-6701
    DOI 10.1016/j.jhin.2022.02.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 1586: Show issues Location:
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  5. Article ; Online: Nutrition and dietary restrictions in cancer prevention.

    Mishra, Amrendra / Giuliani, Giacomo / Longo, Valter D

    Biochimica et biophysica acta. Reviews on cancer

    2023  Volume 1879, Issue 1, Page(s) 189063

    Abstract: The composition and pattern of dietary intake have emerged as key factors influencing aging, regeneration, and consequently, healthspan and lifespan. Cancer is one of the major diseases more tightly linked with aging, and age-related mortality. Although ... ...

    Abstract The composition and pattern of dietary intake have emerged as key factors influencing aging, regeneration, and consequently, healthspan and lifespan. Cancer is one of the major diseases more tightly linked with aging, and age-related mortality. Although the role of nutrition in cancer incidence is generally well established, we are far from a consensus on how diet influences tumour development in different tissues. In this review, we will discuss how diet and dietary restrictions affect cancer risk and the molecular mechanisms potentially responsible for their effects. We will cover calorie restriction, intermittent fasting, prolonged fasting, fasting-mimicking diet, time-restricted eating, ketogenic diet, high protein diet, Mediterranean diet, and the vegan and vegetarian diets.
    MeSH term(s) Humans ; Diet/adverse effects ; Fasting ; Caloric Restriction ; Aging ; Neoplasms/prevention & control
    Language English
    Publishing date 2023-12-24
    Publishing country Netherlands
    Document type Journal Article ; Review ; Research Support, N.I.H., Extramural
    ZDB-ID 2918802-7
    ISSN 1879-2561 ; 0304-419X
    ISSN (online) 1879-2561
    ISSN 0304-419X
    DOI 10.1016/j.bbcan.2023.189063
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7162: Show issues Location:
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  6. Article ; Online: SUNCT syndrome secondary to multiple sclerosis: Not only trigeminal neuralgia.

    Giuliani, Giada / Zilli, Chiara / Caramia, Francesca / Di Piero, Vittorio / Altieri, Marta

    Multiple sclerosis (Houndmills, Basingstoke, England)

    2024  , Page(s) 13524585241235535

    Abstract: Background: Facial pain in multiple sclerosis is often due to trigeminal neuralgia but atypical pictures can be observed.: Case presentation: A man with primary progressive multiple sclerosis developed severe unilateral facial pain in the right ... ...

    Abstract Background: Facial pain in multiple sclerosis is often due to trigeminal neuralgia but atypical pictures can be observed.
    Case presentation: A man with primary progressive multiple sclerosis developed severe unilateral facial pain in the right orbital region. Spontaneous and triggered attacks were associated with ipsilateral conjunctival injection and lacrimation. A diagnosis of short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing was made, and symptoms significantly improved with lamotrigine.
    Conclusion: Pain is poorly investigated in multiple sclerosis, with a dramatic impact on patients' life quality. In this light, standardized evaluation of pain is needed to improve patient management.
    Language English
    Publishing date 2024-03-01
    Publishing country England
    Document type Journal Article
    ZDB-ID 1290669-4
    ISSN 1477-0970 ; 1352-4585
    ISSN (online) 1477-0970
    ISSN 1352-4585
    DOI 10.1177/13524585241235535
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4428: Show issues Location:
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  7. Article ; Online: Robotic Ultrasound-Guided Central Pancreatectomy with Main Pancreatic Duct Endoscopy Evaluation for High-Risk, Mixed-Type Intraductal Papillary Mucinous Neoplasm.

    Giuliani, Giuseppe / Guerra, Francesco / Matarazzo, Francesco / De Franco, Lorenzo / Di Marino, Michele / Coratti, Andrea

    Annals of surgical oncology

    2024  

    Abstract: Background: Central pancreatectomy (CP) is a parenchymal-sparing technique indicated for the resection of selected lesions of the neck or proximal body of the pancreas.: Materials and methods: A US-guided robotic CP was carried out, and an ... ...

    Abstract Background: Central pancreatectomy (CP) is a parenchymal-sparing technique indicated for the resection of selected lesions of the neck or proximal body of the pancreas.
    Materials and methods: A US-guided robotic CP was carried out, and an intraoperative endoscopic evaluation of the MPD was performed to determine the distal transection level. A transmesocolic, end-to-side, robot-sewn Wirsung-jejunostomy with internal MPD stenting was then created. The procedure was completed with a side-to-side jejunojejunostomy.
    Results: The operative time was 290 min, with negligible blood loss. During the postoperative course, the patient experienced bleeding from a branch of the gastroduodenal artery with subsequent fluid collection, which was successfully treated with angioembolization and percutaneous drainage. He was discharged home on postoperative day 22. Final pathology revealed a non-invasive IPMN with low-grade dysplasia and free surgical margins. At 12 months of follow-up, the patient was doing well, with no evidence of local recurrence and endocrine or exocrine pancreatic insufficiency.
    Conclusions: The combination of robotic surgery with intraoperative US and Wirsungoscopy may offer distinct technical advantages for challenging pancreatectomies that follow the principles of parenchymal-sparing surgery.
    Language English
    Publishing date 2024-03-31
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-024-15231-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 4042: Show issues Location:
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  8. Article: The Menopausal Transition: Is the Hair Follicle "Going through Menopause"?

    Rinaldi, Fabio / Trink, Anna / Mondadori, Giorgia / Giuliani, Giammaria / Pinto, Daniela

    Biomedicines

    2023  Volume 11, Issue 11

    Abstract: This article explores the link between menopause and changes in the hair follicle (HF) lifecycle, focusing on hormonal and metabolic dynamics. During menopause, hormonal fluctuations and aging can impact the HF, leading to phenomena such as thinning, ... ...

    Abstract This article explores the link between menopause and changes in the hair follicle (HF) lifecycle, focusing on hormonal and metabolic dynamics. During menopause, hormonal fluctuations and aging can impact the HF, leading to phenomena such as thinning, loss of volume, and changes in hair texture. These changes are primarily attributed to a decrease in estrogen levels. However, not all women experience significant hair changes during menopause, and the extent of transformations can vary considerably from person to person, influenced by genetic factors, stress, diet, and other elements. Furthermore, menopause mirrors the aging process, affecting metabolism and blood flow to the HFs, influencing the availability of vital nutrients. The article also discusses the key role of energy metabolism in the HF lifecycle and the effect of hormones, particularly estrogens, on metabolic efficiency. The concept of a possible "menopause" clinically independent of menopause is introduced, related to changes in HF metabolism, emphasizing the importance of individual factors such as estrogen receptor responses, genetics, and last but not least, the microbiota in determining these dynamics.
    Language English
    Publishing date 2023-11-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2720867-9
    ISSN 2227-9059
    ISSN 2227-9059
    DOI 10.3390/biomedicines11113041
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Case report: Recurrent nocturnal awakenings in cluster headache: a different type of ghost attack.

    Giuliani, Giada / Gorgoni, Maurizio / Altieri, Marta / Di Piero, Vittorio

    Frontiers in neurology

    2023  Volume 14, Page(s) 1230710

    Abstract: Introduction: Cluster headache (CH) is a trigeminal autonomic cephalalgia characterized by attacks of severe unilateral pain associated with ipsilateral autonomic symptoms. Cluster headache attacks exhibit nocturnal predilection, and sleep disorders ... ...

    Abstract Introduction: Cluster headache (CH) is a trigeminal autonomic cephalalgia characterized by attacks of severe unilateral pain associated with ipsilateral autonomic symptoms. Cluster headache attacks exhibit nocturnal predilection, and sleep disorders could be the first manifestation of an incipient cluster period. Sleep alterations in cluster headache patients may reflect the pivotal role of the hypothalamus, which is crucially involved in the pathophysiology of this primary headache. We describe the case of a patient affected by episodic cluster headache who experienced a sleep disorder after starting therapy with verapamil.
    Case presentation: A 47-year-old man was affected by episodic cluster headache, characterized by attacks of excruciating pain in the left orbital and temporal regions, associated with prominent ipsilateral vegetative symptoms. Headaches occurred during the night, with one or two nocturnal attacks appearing at 11.30-12 p.m. and 4-4.30 a.m. Preventive treatment with verapamil was started, with immediate pain relief. Later, he experienced consecutive nocturnal awakenings for a couple of weeks, always at the same time, without any pain or autonomic symptoms. He was not agitated and did not need to get out of bed; after the awakenings, he reported sleep disturbances with vivid dreams.
    Discussion and conclusion: This case represents the first description of recurrent cyclic nocturnal awakenings, without pain and autonomic symptoms, in a patient with episodic cluster headache during the active phase of a cluster bout. Nocturnal awakenings, started after the introduction of effective preventive therapy, might be an unusual form of "ghost attacks." After the beginning of prophylactic therapy, patients often describe mild pain or localized pressure in the same localization of CH attack. Similarly, the appearance of sleep disturbances, without any pain or vegetative symptoms, should be regarded as a warning sign of a still active cluster bout. Since these manifestations may influence therapeutic management, they should be carefully investigated.
    Language English
    Publishing date 2023-07-26
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2023.1230710
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: The objective assessment of sleep in cluster headache: State of the art and future directions.

    Gorgoni, Maurizio / Giuliani, Giada / Fratino, Mariangela / Di Piero, Vittorio

    Journal of sleep research

    2023  , Page(s) e14103

    Abstract: Several lines of evidence suggest that cluster headache is related to chronobiology and sleep. Nevertheless, the nature of such a relationship is unclear. In this view, the objective evaluation of sleep in cluster headache has strong theoretical and ... ...

    Abstract Several lines of evidence suggest that cluster headache is related to chronobiology and sleep. Nevertheless, the nature of such a relationship is unclear. In this view, the objective evaluation of sleep in cluster headache has strong theoretical and clinical relevance. Here, we provide an in-depth narrative review of the literature on objective sleep assessment in cluster headache. We found that only a small number of studies (N = 12) focused on this topic. The key research aims were directed to assess: (a) the relationship between cluster headache and sleep breathing disorders; (b) the temporal relationship between sleep stages/events and cluster headache attacks; (c) sleep macrostructure in patients with cluster headache. No studies considered sleep microstructure. The reviewed studies are heterogeneous, conducted by a few research groups, and often characterised by relevant methodological flaws. Results are substantially inconclusive considering the main hypothesis. We outline several methodological points that should be considered for future research, and suggest that evaluating sleep microstructure, local sleep electrophysiology and actigraphic measures may strongly increase knowledge on the relationship between sleep and cluster headache.
    Language English
    Publishing date 2023-11-14
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1122722-9
    ISSN 1365-2869 ; 0962-1105
    ISSN (online) 1365-2869
    ISSN 0962-1105
    DOI 10.1111/jsr.14103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 3464: Show issues Location:
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    Zs.MO 343: Show issues

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