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Article ; Online: Cateterismo cardiaco destro: “tips and tricks”.

Giuliani, Livio / Rossi, Serena

Giornale italiano di cardiologia (2006)

2020 Volume 21, Issue 6 Suppl 1, Page(s) 46S–54S

Abstract: Right heart catheterization (RHC) is a key diagnostic tool in several clinical conditions. It is recognized to be a technically demanding procedure requiring accurate evaluation of results. If performed by skilled operators, RHC provides reliable and ... ...

Title translation	Right heart catheterization: tips and tricks.
Abstract	Right heart catheterization (RHC) is a key diagnostic tool in several clinical conditions. It is recognized to be a technically demanding procedure requiring accurate evaluation of results. If performed by skilled operators, RHC provides reliable and valuable measurements with low complication rates. Although increasing data from the literature have become available over time, a comprehensive review of technical details and pitfalls is rare. This article aims to provide an overview of indications and evidence-based practical issues upon RHC to guide interventional cardiologists on how to perform this procedure.
MeSH term(s)	Cardiac Catheterization/adverse effects ; Cardiac Catheterization/methods ; Cardiologists ; Cardiovascular Diseases/diagnosis ; Cardiovascular Diseases/physiopathology ; Clinical Competence ; Evidence-Based Medicine ; Humans
Language	Italian
Publishing date	2020-05-29
Publishing country	Italy
Document type	Journal Article ; Review
ZDB-ID	2272414-X
ISSN	1972-6481 ; 1827-6806
ISSN (online)	1972-6481
ISSN	1827-6806
DOI	10.1714/3373.33493
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Article ; Online: Left Ventricle Unloading, Coronary Artery Oxygenation, or Both?

Giuliani, Livio / Archilletti, Federico

Cardiovascular revascularization medicine : including molecular interventions

2020 Volume 21, Issue 5, Page(s) 699

MeSH term(s)	Coronary Vessels ; Heart Ventricles ; Humans ; Oxygenators, Membrane ; ST Elevation Myocardial Infarction ; Shock, Cardiogenic
Language	English
Publishing date	2020-02-13
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	2212113-4
ISSN	1878-0938 ; 1553-8389
ISSN (online)	1878-0938
ISSN	1553-8389
DOI	10.1016/j.carrev.2020.02.009
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Article ; Online: The carcinogenic potential of non-ionizing radiations: The cases of S-50 Hz MF and 1.8 GHz GSM radiofrequency radiation.

Soffritti, Morando / Giuliani, Livio

Basic & clinical pharmacology & toxicology

2019 Volume 125 Suppl 3, Page(s) 58–69

Abstract: Epidemiological studies have suggested that human exposure to extremely low-frequency electromagnetic fields from the electric power and to mobile phone radiofrequency electromagnetic fields induce an increased risk of developing malignant tumours. ... ...

Abstract	Epidemiological studies have suggested that human exposure to extremely low-frequency electromagnetic fields from the electric power and to mobile phone radiofrequency electromagnetic fields induce an increased risk of developing malignant tumours. However, no adequate laboratory data, in particular long-term carcinogenicity bioassays to support the epidemiological evidence, have yet been available. This motivated the Ramazzini Institute to embark on a first project of four large life-span carcinogenic bioassays conducted on over 7000 Sprague Dawley rats exposed from prenatal life until natural death to S-50 Hz MF alone or combined with gamma radiation or formaldehyde or aflatoxin B1. Results now available from these studies, which started concurrently, have shown that exposure to Sinusoidal-50 Hz Magnetic Field (S-50 Hz MF) combined with acute exposure to gamma radiation or to chronic administration of formaldehyde in drinking water induces a significantly increased incidence of malignant tumours in males and females. A second project of two large life-span carcinogenic bioassays was conducted on over 3000 Sprague Dawley rats exposed from prenatal life until natural death to 1.8 GHz GSM of mobile phone radio base station, alone or combined with acute exposure to gamma radiation. Early results from the experiment on 1.8 GHz GSM alone show a statistically significant increase in the incidence of heart malignant schwannoma among males exposed at the highest dose.
MeSH term(s)	Animals ; Carcinogenesis/radiation effects ; Disease Models, Animal ; Electromagnetic Fields/adverse effects ; Environmental Exposure/adverse effects ; Female ; Humans ; Incidence ; Neoplasms/epidemiology ; Neoplasms/etiology ; Neoplasms/prevention & control ; Pregnancy ; Prenatal Exposure Delayed Effects/epidemiology ; Prenatal Exposure Delayed Effects/etiology ; Prenatal Exposure Delayed Effects/prevention & control ; Radiation, Nonionizing/adverse effects ; Rats, Sprague-Dawley
Language	English
Publishing date	2019-03-25
Publishing country	England
Document type	Journal Article ; Review
ZDB-ID	2134679-3
ISSN	1742-7843 ; 1742-7835
ISSN (online)	1742-7843
ISSN	1742-7835
DOI	10.1111/bcpt.13215
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Article ; Online: WiFi Related Radiofrequency Electromagnetic Fields Promote Transposable Element Dysregulation and Genomic Instability in

Cappucci, Ugo / Casale, Assunta Maria / Proietti, Mirena / Marinelli, Fiorenzo / Giuliani, Livio / Piacentini, Lucia

Cells

2022 Volume 11, Issue 24

Abstract: Exposure to artificial radio frequency electromagnetic fields (RF-EMFs) has greatly increased in recent years, thus promoting a growing scientific and social interest in deepening the biological impact of EMFs on living organisms. The current legislation ...

Abstract	Exposure to artificial radio frequency electromagnetic fields (RF-EMFs) has greatly increased in recent years, thus promoting a growing scientific and social interest in deepening the biological impact of EMFs on living organisms. The current legislation governing the exposure to RF-EMFs is based exclusively on their thermal effects, without considering the possible non-thermal adverse health effects from long term exposure to EMFs. In this study we investigated the biological non-thermal effects of low-level indoor exposure to RF-EMFs produced by WiFi wireless technologies, using
Language	English
Publishing date	2022-12-13
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2661518-6
ISSN	2073-4409 ; 2073-4409
ISSN (online)	2073-4409
ISSN	2073-4409
DOI	10.3390/cells11244036
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Article ; Online: Impella CP and Veno-Arterial Extracorporeal Membrane Oxygenator as a sequential add-on combination circulatory support in ST-segment elevation myocardial infarction complicated by cardiogenic shock.

Giuliani, Livio / Archilletti, Federico / Rossi, Serena / Maddestra, Nicola

Cardiovascular revascularization medicine : including molecular interventions

2019 Volume 20, Issue 11S, Page(s) 60–62

Abstract: A 48-year-old male was admitted to our institution with an anteroseptal ST-elevation myocardial infarction and angiographic evidence of a thrombotic occlusion in the ostial segment of the left anterior descending coronary artery. The percutaneous ... ...

Abstract	A 48-year-old male was admitted to our institution with an anteroseptal ST-elevation myocardial infarction and angiographic evidence of a thrombotic occlusion in the ostial segment of the left anterior descending coronary artery. The percutaneous coronary intervention resulted in "no-reflow" and cardiogenic shock. We describe our successful management strategy with sequentially combined implantation of Impella CP and Extracorporeal Membrane Oxygenator.
MeSH term(s)	Angioplasty, Balloon, Coronary/adverse effects ; Extracorporeal Membrane Oxygenation ; Heart-Assist Devices ; Hemodynamics ; Humans ; Male ; Middle Aged ; No-Reflow Phenomenon/diagnosis ; No-Reflow Phenomenon/etiology ; No-Reflow Phenomenon/physiopathology ; No-Reflow Phenomenon/therapy ; Recovery of Function ; Respiration ; Respiratory Distress Syndrome, Adult/diagnosis ; Respiratory Distress Syndrome, Adult/etiology ; Respiratory Distress Syndrome, Adult/physiopathology ; Respiratory Distress Syndrome, Adult/therapy ; ST Elevation Myocardial Infarction/diagnostic imaging ; ST Elevation Myocardial Infarction/physiopathology ; ST Elevation Myocardial Infarction/therapy ; Shock, Cardiogenic/diagnosis ; Shock, Cardiogenic/etiology ; Shock, Cardiogenic/physiopathology ; Shock, Cardiogenic/therapy ; Treatment Outcome ; Ventricular Function, Left
Language	English
Publishing date	2019-08-09
Publishing country	United States
Document type	Case Reports
ZDB-ID	2212113-4
ISSN	1878-0938 ; 1553-8389
ISSN (online)	1878-0938
ISSN	1553-8389
DOI	10.1016/j.carrev.2019.08.002
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Article ; Online: Upfront triple oral combination therapy including selexipag in a high-risk patient with idiopathic pulmonary arterial hypertension: a case report.

Rossi, Serena / Pietrangelo, Carla / Pierdomenico, Sante Donato / Giuliani, Livio

European heart journal. Case reports

2020 Volume 4, Issue 5, Page(s) 1–5

Abstract: Background: Selexipag is an oral selective prostacyclin IP receptor agonist approved in patients with low- and intermediate-risk pulmonary hypertension (PH); evidence in patients at high risk is lacking.: Case summary: A 42-year-old woman with ... ...

Abstract	Background: Selexipag is an oral selective prostacyclin IP receptor agonist approved in patients with low- and intermediate-risk pulmonary hypertension (PH); evidence in patients at high risk is lacking. Case summary: A 42-year-old woman with worsening dyspnoea (World Health Organization functional class III-IV) and suspected PH at echocardiographic examination was evaluated in our Pulmonary Hypertension Centre. Right heart catheterization showed pre-capillary PH with reduced cardiac index and increased pulmonary vascular resistance. High-resolution computed tomography excluded parenchymal lung disease and ventilation/perfusion (V/Q) lung scan was negative for mismatched perfusion defects so the conclusive diagnosis was high-risk idiopathic pulmonary arterial hypertension (PAH). The patient refused an initial combination therapy including a parenteral prostacyclin analogue (PCA) in accordance with the ESC/ERS guidelines, so an off-label triple oral combination therapy including a phosphodiesterase-5 inhibitor, an endothelin receptor antagonist, and selexipag was started. At 3- and 6-month follow-up we found a clinical and haemodynamic improvement, so the patient was reclassified as low risk. Her clinical condition is currently stable. Discussion: Despite the benefit of parenteral PCAs in high-risk PAH, low adherence to treatment may be explained by adverse side effects related to the intravenous route of administration. Given the potential effect seen in our patient, upfront triple oral combination therapy in PAH high-risk patients should be further evaluated in a controlled clinical trial.
Language	English
Publishing date	2020-08-30
Publishing country	England
Document type	Case Reports
ISSN	2514-2119
ISSN (online)	2514-2119
DOI	10.1093/ehjcr/ytaa190
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Article ; Online: The awareness of radial access for coronary procedures.

Zimarino, Marco / Giuliani, Livio / Maddestra, Nicola

Cardiovascular revascularization medicine : including molecular interventions

2017 Volume 18, Issue 3, Page(s) 151–152

MeSH term(s)	Angioplasty, Balloon, Coronary ; Coronary Angiography ; Femoral Artery ; Humans ; Radial Artery
Language	English
Publishing date	2017-04
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	2212113-4
ISSN	1878-0938 ; 1553-8389
ISSN (online)	1878-0938
ISSN	1553-8389
DOI	10.1016/j.carrev.2017.02.007
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Book: Non-thermal effects and mechanisms of interaction between electromagnetic fields and living matter

Giuliani, Livio / Soffritti, Morando

(Ramazzini Institute Eur. J. Oncol. library ; 5)

2010

Institution	National Institute for the Study and Control of Cancer and Enviromental Diseases "Bernardino Ramazzini" (Italy) Istituto Ramazzini. International Commission for Electromagnetic Safety
Author's details	edited by Livio Giuliani, Morando Soffritti
Series title	Ramazzini Institute Eur. J. Oncol. library ; 5
MeSH term(s)	Electromagnetic Fields/adverse effects ; Radiation, Nonionizing/adverse effects ; Biophysical Phenomena/physiology
Language	English
Size	xi, 403 p. :, ill.
Publisher	National Institute for the Study and Control of Cancer and Enviromental Diseases "Bernardino Ramazzini" ; Mattioli
Publishing place	Bologna ; Fidenza (Parma)
Document type	Book
Note	"An ICEMS monograph." ; "European Journal of Oncology"--Cover.
ISBN	9788862611664 ; 8862611668
Database	Catalogue of the US National Library of Medicine (NLM)

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Article ; Online: Il cateterismo cardiaco destro nei laboratori di emodinamica italiani: risultati dell’indagine nazionale SICI-GISE promossa dal Comitato GISE Young.

Compagnone, Miriam / Demola, Pierluigi / Serino, Federica / Masiero, Giulia / Giuliani, Livio / Rossi, Serena / Polimeni, Alberto / Attisano, Tiziana / Contarini, Marco / Castiglioni, Battistina / De Marco, Federico / Fineschi, Massimo / Menozzi, Alberto / Musto, Carmine / Saia, Francesco / Tarantini, Giuseppe / Esposito, Giovanni

Giornale italiano di cardiologia (2006)

2023 Volume 24, Issue 4 Suppl 2, Page(s) 30S–38S

Abstract: Background: Over the past decades, the improvements in the diagnostic power and availability of non-invasive cardiac imaging techniques have led to a decline of right heart catheterization (RHC) performance. However, RHC remains the gold standard for ... ...

Title translation	Right heart catheterization in Italian catheterization laboratories: results of the SICI-GISE national survey promoted by the GISE Young Committee.
Abstract	Background: Over the past decades, the improvements in the diagnostic power and availability of non-invasive cardiac imaging techniques have led to a decline of right heart catheterization (RHC) performance. However, RHC remains the gold standard for diagnosing pulmonary hypertension and an essential tool for the evaluation of patient candidacy to heart transplantation. Methods: This survey was carried out jointly by the Young Committee of GISE, with the support of the SICI-GISE Society, and the ICOT group, with the aim of evaluating how the interventional cardiology community perform RHC. A web-based questionnaire based on 20 questions was distributed to SICI-GISE members. Results: The survey was distributed to 1550 physicians with 174 (11%) responses. Most centers perform few procedures per year (<10 RHC/year) and a dedicated cardiologist is usually lacking. Patients were frequently admitted as ordinary hospitalization regimen and the most frequent indication for RHC was the hemodynamic assessment of pulmonary hypertension, followed by diagnostics of valvular diseases and advanced heart failure/heart transplantation. Indeed, the majority of participants (86%) are involved in transcatheter procedures for structural heart disease. The average time taken to perform the RHC was approximately 30-60 min. The femoral access (60%) was the most frequently used, usually by an echo-guided approach. Two-thirds of participants discontinued oral anticoagulant therapy before RHC. Only 27% of centers assess wedge position from an integrated analysis. Furthermore, the edge pressure is detected in the end-diastolic cardiac phase in half cases and in the end-expiratory phase in only 31%. The most commonly used method for cardiac output calculation was the indirect Fick method (58%). Conclusions: Guidance on the best practice for performing RHC is currently lacking. A more precise standardization of this demanding procedure is warranted.
MeSH term(s)	Humans ; Hypertension, Pulmonary ; Laboratories ; Cardiac Catheterization/methods ; Surveys and Questionnaires ; Italy ; Anticoagulants
Chemical Substances	Anticoagulants
Language	Italian
Publishing date	2023-05-09
Publishing country	Italy
Document type	English Abstract ; Journal Article
ZDB-ID	2272414-X
ISSN	1972-6481 ; 1827-6806
ISSN (online)	1972-6481
ISSN	1827-6806
DOI	10.1714/4035.40105
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Article ; Online: Coronary angiography- or fractional flow reserve-guided complete revascularization in multivessel disease STEMI: A Bayesian hierarchical network meta-analysis.

Archilletti, Federico / Ricci, Fabrizio / Pelliccia, Francesco / Dangas, George / Giuliani, Livio / Radico, Francesco / Perfetti, Matteo / Rossi, Serena / Gallina, Sabina / Maddestra, Nicola / Khanji, Mohammed Y / Zimarino, Marco

International journal of cardiology

2022 Volume 370, Page(s) 122–128

Abstract: Aims: To identify the best strategy to achieve complete revascularization (CR) in patients with ST-elevation myocardial infarction (STEMI) and multi-vessel disease (MVD).: Methods and results: We systematically reviewed the literature for randomized ... ...

Abstract	Aims: To identify the best strategy to achieve complete revascularization (CR) in patients with ST-elevation myocardial infarction (STEMI) and multi-vessel disease (MVD). Methods and results: We systematically reviewed the literature for randomized controlled trials (RCTs) comparing IRA-only PCI and CR guided by angiography or fractional flow reserve (FFR) in MVD-STEMI. Both frequentist (classical) and Bayesian network meta-analysis were performed, including a comparative hierarchy estimation of the probability to reduce the primary composite endpoint of all-cause death and new myocardial infarction (MI). We identified 11 RCTs, including 8193 STEMI patients. Compared with IRA-only strategy, CR significantly reduced the primary endpoint (OR: 0.73; 95%CI0.55-0.97). We observed non-significant difference between angiography and FFR guidance in reducing the primary endpoint (OR: 0.73, 95% CI 0.35-1.57). The Bayesian probability analysis ranked angio-guided CR as the best intervention yielding lowest risk of all-cause death or new MI (SUCRA92%). Conclusions: In patients with MVD-STEMI, CR is associated with a reduction in all-cause mortality and new MI compared with IRA-only PCI. Angio-guided CR is associated with the lowest risk of all-cause death or new MI, therefore the role of FFR-guidance in this setting is questionable. Condensed abstract: Both frequentist and Bayesian network meta-analysis were performed to compare infarct-related artery (IRA)-only percutaneous coronary intervention (PCI) and complete revascularization (CR) guided by angiography or fractional flow reserve (FFR) in multivessel disease (MVD) and acute ST-elevation myocardial infarction (STEMI). Eleven randomized controlled trials were identified, including 8193 STEMI patients. Compared with IRA-only strategy, CR significantly reduced the incidence of the composite endpoint of all-cause death and new myocardial infarction without significant difference in angio-guided and FFR-guided CR. The Bayesian probability analysis ranked angio-guided CR as the best intervention yielding lowest risk of the composite endpoint and, therefore the role of FFR-guidance in this setting is questionable.
Language	English
Publishing date	2022-10-31
Publishing country	Netherlands
Document type	Journal Article
ZDB-ID	779519-1
ISSN	1874-1754 ; 0167-5273
ISSN (online)	1874-1754
ISSN	0167-5273
DOI	10.1016/j.ijcard.2022.10.170
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