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Article: Seasonality of antimicrobial resistance rates in respiratory bacteria: A systematic review and meta-analysis

Martinez Lopez, Pamela / Glisic, Marija / Franco, Oscar

PLOS ONE, 14(8):e0221133

2019

Abstract: BACKGROUND: Antimicrobial resistance (AMR) rates may display seasonal variation. However, it is not clear whether this seasonality is influenced by the seasonal variation of infectious diseases, geographical region or differences in antibiotic ... ...

Institution	Leibniz-Institut für Präventionsforschung und Epidemiologie
Abstract	BACKGROUND: Antimicrobial resistance (AMR) rates may display seasonal variation. However, it is not clear whether this seasonality is influenced by the seasonal variation of infectious diseases, geographical region or differences in antibiotic prescription patterns. Therefore, we assessed the seasonality of AMR rates in respiratory bacteria. METHODS: Seven electronic databases (Embase.com, Medline Ovid, Cochrane CENTRAL, Web of Science, Core Collection, Biosis Ovid, and Google Scholar), were searched for relevant studies from inception to Jun 25th, 2019. Studies describing resistance rates of Streptococcus pneumoniae and Haemophilus influenzae were included in this review. By using random-effects meta-analysis, pooled odd ratios of seasonal AMR rates were calculated using winter as the reference group. Pooled odd ratios were obtained by antibiotic class and geographical region. RESULTS: We included 13 studies, of which 7 were meta-analyzed. Few studies were done in H. influenzae, thus this was not quantitively analyzed. AMR rates of S. pneumoniae to penicillins were lower in other seasons than in winter with pooled OR = 0.71; 95% CI = 0.65–0.77; I2 = 0.0%, and to all antibiotics with pooled OR = 0.68; 95% CI = 0.60–0.76; I2 = 14.4%. Irrespective of geographical region, the seasonality of AMR rates in S. pneumoniae remained the same. CONCLUSION: The seasonality of AMR rates could result from the seasonality of infectious diseases and its accompanied antibiotic use.
Keywords	Antimicrobial resistance ; Antibiotics ; Antibiotic resistance ; Metaanalysis ; Seasons ; Pneumococcus ; Respiratory infections ; Winter
Language	English
Document type	Article
Database	Repository for Life Sciences

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Article: Epigenetics and Inflammatory Markers: A Systematic Review of the Current Evidence

gonzalez jaramillo, valentina / Portilla-Fernandez, Eliana / Glisic, Marija

International journal of inflammation, 2019:6273680

2019

Abstract: Epigenetic mechanisms have been suggested to play a role in the genetic regulation of pathways related to inflammation. Therefore, we aimed to systematically review studies investigating the association between DNA methylation and histone modifications ... ...

Institution	Leibniz-Institut für Präventionsforschung und Epidemiologie
Abstract	Epigenetic mechanisms have been suggested to play a role in the genetic regulation of pathways related to inflammation. Therefore, we aimed to systematically review studies investigating the association between DNA methylation and histone modifications with circulatory inflammation markers in blood. Five bibliographic databases were screened until 21 November of 2017. We included studies conducted on humans that examined the association between epigenetic marks (DNA methylation and/or histone modifications) and a comprehensive list of inflammatory markers. Of the 3,759 identified references, 24 articles were included, involving, 17,399 individuals. There was suggestive evidence for global hypomethylation but better-quality studies in the future have to confirm this. Epigenome-wide association studies (EWAS) (n=7) reported most of the identified differentially methylated genes to be hypomethylated in inflammatory processes. Candidate genes studies reported 18 differentially methylated genes related to several circulatory inflammation markers. There was no overlap in the methylated sites investigated in candidate gene studies and EWAS, except for TMEM49, which was found to be hypomethylated with higher inflammatory markers in both types of studies. The relation between histone modifications and inflammatory markers was assessed by one study only. This review supports an association between epigenetic marks and inflammation, suggesting hypomethylation of the genome. Important gaps in the quality of studies were reported such as inadequate sample size, lack of adjustment for relevant confounders, and failure to replicate the findings. While most of the studies have been focused on C-reactive protein, further efforts should investigate other inflammatory markers.
Language	English
Document type	Article
Database	Repository for Life Sciences

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Article: Dietary Factors and Modulation of Bacteria Strains of Akkermansia muciniphila and Faecalibacterium prausnitzii: A Systematic Review

Verhoog, Sanne / Roa Díaz, Zayne Milena / Marques-Vidal, Pedro / Glisic, Marija

Nutrients, 11(7):1565

2019

Abstract: Akkermansia muciniphila and Faecalibacterium prausnitzii are highly abundant human gut microbes in healthy individuals, and reduced levels are associated with inflammation and alterations of metabolic processes involved in the development of type 2 ... ...

Institution	Leibniz-Institut für Präventionsforschung und Epidemiologie
Abstract	Akkermansia muciniphila and Faecalibacterium prausnitzii are highly abundant human gut microbes in healthy individuals, and reduced levels are associated with inflammation and alterations of metabolic processes involved in the development of type 2 diabetes. Dietary factors can influence the abundance of A. muciniphila and F. prausnitzii, but the evidence is not clear. We systematically searched PubMed and Embase to identify clinical trials investigating any dietary intervention in relation to A. muciniphila and F. prausnitzii. Overall, 29 unique trials were included, of which five examined A. muciniphila, 19 examined F. prausnitzii, and six examined both, in a total of 1444 participants. A caloric restriction diet and supplementation with pomegranate extract, resveratrol, polydextrose, yeast fermentate, sodium butyrate, and inulin increased the abundance of A. muciniphila, while a diet low in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols decreased the abundance of A. muciniphila. For F. prausnitzii, the main studied intervention was prebiotics (e.g. fructo-oligosaccharides, inulin type fructans, raffinose); seven studies reported an increase after prebiotic intervention, while two studies reported a decrease, and four studies reported no difference. Current evidence suggests that some dietary factors may influence the abundance of A. muciniphila and F. prausnitzii. However, more research is needed to support these microflora strains as targets of microbiome shifts with dietary intervention and their use as medical nutrition therapy in prevention and management of chronic disease.
Keywords	Akkermansia muciniphila ; Dietary interventions ; Faecalibacterium prausnitzii ; Microbiome ; Systematic review ; Randomized controlled trials
Language	English
Document type	Article
Database	Repository for Life Sciences

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Article ; Online: Volumetric mapping and visualization of life cycle assessment results on computer-aided design models

Vernica, Teodor / Glišić, Marija / Veluri, Badrinath / Ramanujan, Devarajan

Journal of Cleaner Production. 2023 Sept., v. 418 p.138035-

2023

Abstract: Life cycle assessments (LCAs) are widely used for identifying opportunities for redesigning engineered parts from a sustainability perspective. However, the data representations and results visualizations used in LCAs remain disconnected from those used ... ...

Abstract	Life cycle assessments (LCAs) are widely used for identifying opportunities for redesigning engineered parts from a sustainability perspective. However, the data representations and results visualizations used in LCAs remain disconnected from those used for engineering design; this makes it challenging to apply results from LCAs towards redesign decision-making. To address this gap, this paper presents a novel voxel-based approach for mapping process-based life cycle inventory data (and consequently LCA results) to three-dimensional CAD models. The proposed approach can be flexibly applied at different resolutions, i.e., part-level, feature-level, and individual voxel-level based on the granularity of information available. Furthermore, it enables volumetric visualization of LCA results directly on the three-dimensional model of the part. A real-world case study on mapping and visualizing LCA results of a shaft and rotor sub-assembly manufacturing process is used for demonstrating the merits and limitations of the proposed approach.
Keywords	case studies ; computer-aided design ; decision making ; life cycle inventory ; models ; Life cycle assessment ; Scientific visualization
Language	English
Dates of publication	2023-09
Publishing place	Elsevier Ltd
Document type	Article ; Online
Note	Pre-press version
ISSN	0959-6526
DOI	10.1016/j.jclepro.2023.138035
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Characteristics of the gut microbiome of Swiss elite athletes with a spinal cord injury: An exploratory study.

Valido, Ezra / Bertolo, Alessandro / Hertig-Godeschalk, Anneke / Flueck, Joelle Leonie / Ruettimann, Belinda / Glisic, Marija / Stoyanov, Jivko

The journal of spinal cord medicine

2024 , Page(s) 1–9

Abstract: Objectives: To illustrate and explore associations between the gut microbiome and spinal cord injury (SCI) characteristics, physical training, dietary intake, body composition, and blood biomarkers of elite Swiss athletes.: Design and setting: ... ...

Abstract	Objectives: To illustrate and explore associations between the gut microbiome and spinal cord injury (SCI) characteristics, physical training, dietary intake, body composition, and blood biomarkers of elite Swiss athletes. Design and setting: Baseline data analysis of athletes with SCI who participated in a pilot trial (NCT04659408) in the Swiss Paraplegic Center, Nottwil, Switzerland. Participants: Elite athletes, five males, and six females, with SCI who competed internationally. Outcome measures: We conducted a differential abundance analysis and measured the alpha and beta diversity of the gut microbiome. Results: The athletes' median age was 34.5 years. Six had traumatic SCI and five had a spina bifida. The athletes competed in para-cycling (5), wheelchair athletics (3), and wheelchair tennis (3). A higher duration of training per week was positively associated with Conclusions: This study provides insight into the gut microbiome of athletes with SCI. Our results were similar to those found in athletes without SCI. Further replication is needed to confirm the relationships of organisms observed in the gut of athletes with SCI.
Language	English
Publishing date	2024-01-11
Publishing country	England
Document type	Journal Article
ZDB-ID	1223949-5
ISSN	2045-7723 ; 1079-0268
ISSN (online)	2045-7723
ISSN	1079-0268
DOI	10.1080/10790268.2023.2265610
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Article ; Online: Energy Availability and Nutritional Intake during Different Training Phases of Wheelchair Athletes.

Hertig-Godeschalk, Anneke / Ruettimann, Belinda / Valido, Ezra / Glisic, Marija / Stoyanov, Jivko / Flueck, Joelle L

Nutrients

2023 Volume 15, Issue 11

Abstract: Optimizing nutritional intake and timing helps athletes to improve performance and long-term health. Different training phases can require varying nutritional needs. In this study, we conducted a descriptive assessment of dietary intake, energy ... ...

Abstract	Optimizing nutritional intake and timing helps athletes to improve performance and long-term health. Different training phases can require varying nutritional needs. In this study, we conducted a descriptive assessment of dietary intake, energy availability (EA), and blood biochemical parameters in elite wheelchair athletes during distinct training phases. Data analyzed in this study were collected as part of a randomized controlled crossover trial exploring the feasibility of probiotics and prebiotic supplementation. Data were obtained from consecutive three-day diaries and blood samples, both collected at four different time points across four consecutive months. We included 14 athletes (mean (standard deviation) age 34 (9) years, eight females, and six males) active in different wheelchair sports. The mean daily nutritional intake (g/kg body mass) for females and males was 2.7 (0.9) and 4.0 (0.7) for carbohydrates, 1.1 (0.3) and 1.5 (0.3) for protein, and 0.8 (0.3) and 1.4 (0.2) for fat. EA did not change across the four time points in either female (
MeSH term(s)	Humans ; Male ; Female ; Adult ; Para-Athletes ; Athletes ; Eating ; Vitamin D ; Sports for Persons with Disabilities ; Energy Intake ; Sports Nutritional Physiological Phenomena
Chemical Substances	Vitamin D (1406-16-2)
Language	English
Publishing date	2023-05-31
Publishing country	Switzerland
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2518386-2
ISSN	2072-6643 ; 2072-6643
ISSN (online)	2072-6643
ISSN	2072-6643
DOI	10.3390/nu15112578
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Article ; Online: Are Positive Psychology Interventions Efficacious in Chronic Pain Treatment? A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Braunwalder, Céline / Müller, Rachel / Glisic, Marija / Fekete, Christine

Pain medicine (Malden, Mass.)

2021 Volume 23, Issue 1, Page(s) 122–136

Abstract: Objective: Although positive psychology interventions (PPIs) are increasingly popular in chronic pain treatment their efficacy is still unclear. The objective is to summarize evidence on the effect of PPIs on pain, physical functioning, and emotional ... ...

Abstract	Objective: Although positive psychology interventions (PPIs) are increasingly popular in chronic pain treatment their efficacy is still unclear. The objective is to summarize evidence on the effect of PPIs on pain, physical functioning, and emotional functioning in adults with chronic pain. Methods: Four electronic databases and additional references were searched for randomized controlled trials (RCTs) published between 1990 and 2020. Findings from included studies were qualitatively and quantitatively synthesized, and study quality was assessed for risk of bias. A random effects meta-analysis model was applied for outcomes with more than four findings. Results: Of 16 included RCTs, almost half delivered PPIs as self-help online interventions, and half conducted guided face-to-face interventions which lasted mostly eight weeks. Results from meta-analysis showed beneficial effects of PPIs compared to the control group on pain intensity and emotional functioning (i.e., less depressive symptoms, pain catastrophizing, negative affect; more positive affect) post-intervention. At 3-month follow-up, beneficial effects were maintained for depressive symptoms and positive and negative affect, but not for pain catastrophizing. However, the evidence on the long-term efficacy of PPIs and the efficacy of PPIs on physical functioning remains limited. Conclusions: This review supports the notion that PPIs are beneficial to chronic pain treatment, although further, high quality research is needed to support this conclusion.
MeSH term(s)	Adult ; Chronic Pain/psychology ; Chronic Pain/therapy ; Humans ; Pain Management/methods ; Psychology, Positive ; Randomized Controlled Trials as Topic
Language	English
Publishing date	2021-08-04
Publishing country	England
Document type	Journal Article ; Meta-Analysis ; Research Support, Non-U.S. Gov't ; Systematic Review
ZDB-ID	2015903-1
ISSN	1526-4637 ; 1526-2375
ISSN (online)	1526-4637
ISSN	1526-2375
DOI	10.1093/pm/pnab247
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Article ; Online: Sex and gender gap in spinal cord injury research: Focus on cardiometabolic diseases. A mini review.

Raguindin, Peter Francis / Muka, Taulant / Glisic, Marija

Maturitas

2021 Volume 147, Page(s) 14–18

Abstract: Cardiometabolic disease (CMD) is among the leading causes of morbidity and mortality in people with a spinal cord injury (SCI). Despite well-acknowledged sex and gender differences in CMD in the general population, they remain insufficiently studied in ... ...

Abstract	Cardiometabolic disease (CMD) is among the leading causes of morbidity and mortality in people with a spinal cord injury (SCI). Despite well-acknowledged sex and gender differences in CMD in the general population, they remain insufficiently studied in persons with SCI. To describe the landscape of sex and gender in SCI research, we searched the literature for systematic reviews on cardiometabolic health in this population. Out of 15 systematic reviews identified, only 9 provided meaningful information on sex. Although one-quarter to one-fifth of the SCI population is female, women comprised only one-eighth to a quarter of study participants. A number of clinical studies purposively excluded women, to make the study population more homogenous. For those studies which included both sexes, in general, no sex-specific analyses were performed due to small sample sizes. All these reasons have contributed to the underrepresentation of females in the current body of evidence. Therefore, future studies should adopt a more sex- and gender-sensitive research framework to address cardiometabolic risk in SCI. Novel and advanced epidemiological methods should also be used, considering small sample sizes. Finally, collaborative research (through consortia and multi-center studies) should be encouraged to include more females. More inclusive research will ensure that everyone will benefit from scientific advancements, regardless of sex and gender.
MeSH term(s)	Biomedical Research ; Cardiovascular Diseases ; Humans ; Sex Factors ; Spinal Cord Injuries
Language	English
Publishing date	2021-03-04
Publishing country	Ireland
Document type	Journal Article ; Review
ZDB-ID	80460-5
ISSN	1873-4111 ; 0378-5122
ISSN (online)	1873-4111
ISSN	0378-5122
DOI	10.1016/j.maturitas.2021.03.004
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Zs.A 1432: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Article ; Online: Systematic review and meta-analysis use in the field of spinal cord injury research: A bibliometric analysis.

Stojic, Stevan / Minder, Beatrice / Boehl, Gabriela / Rivero, Tania / Zwahlen, Marcel / Gemperli, Armin / Glisic, Marija

The journal of spinal cord medicine

2023 , Page(s) 1–11

Abstract: Objective: To subvert issues of low sample sizes and high attrition rates and generate epidemiologically-sound evidence, collaborative research-through international consortia and multi-centric studies-and meta-analysis approaches are encouraged in ... ...

Abstract	Objective: To subvert issues of low sample sizes and high attrition rates and generate epidemiologically-sound evidence, collaborative research-through international consortia and multi-centric studies-and meta-analysis approaches are encouraged in spinal cord injury (SCI) research. We investigated the use of systematic reviews and meta-analyses (SRMA) methodology in SCI research and evaluated the quality of evidence across publications we identified. Methods: We searched the Web of Science Core Collection database by topic without time or language restrictions through 16 December 2022. We identified additional relevant articles through Embase.com. SRMA including human and animal SCI populations were eligible for inclusion. We analyzed data using Bibliometrix and VOSviewer. We used the JBI tool (former Joanna Briggs Institute) to assess methodological quality of a subset of 50 randomly selected articles. Results: We based our analysis on data from 1'224 documents authored by 5'237 scholars and published in 424 sources between 1985 and 2022. The use of SRMA methodology in the field gained momentum in 2009 and a steady increase followed with an annual growth rate of ≈15%. Our findings indicate major research themes in the field include recovery, SCI management, rehabilitation, and quality of life. Over the past 30 years there has been a shift from SRMA concerning functional recovery, secondary health complications, and quality of life toward biomarkers and neuro-regeneration. The major methodological issues across articles we evaluated included opaquely described search strategies, poorly reported critical appraisals, and insufficiently addressing publication bias. In addition, only one-fifth of articles reported review protocol registration. Conclusions: : Our bibliometric analysis clearly shows a rapid increase of SRMA applications in SCI research. We discuss the most important methodological concerns we identified among a randomly selected set of articles and provide guidance for improving adherence to methodological and reporting SRMA guidelines.
Language	English
Publishing date	2023-09-08
Publishing country	England
Document type	Journal Article
ZDB-ID	1223949-5
ISSN	2045-7723 ; 1079-0268
ISSN (online)	2045-7723
ISSN	1079-0268
DOI	10.1080/10790268.2023.2251205
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Article ; Online: Significance of Schroth method in the rehabilitation of children with structural idiopathic scoliosis

Vrećić Aleksandra / Glišić Marija / Živković Vesna

Medicinski Podmladak, Vol 71, Iss 1, Pp 33-

2020 Volume 38

Abstract: Introduction: Scoliosis is a multifactorial three-dimensional spinal deformation. Adolescent idiopathic structural scoliosis (AIS) is the most common spinal deformity in children. Specific physiotherapeutic exercises are recommended as the first step in ... ...

Abstract	Introduction: Scoliosis is a multifactorial three-dimensional spinal deformation. Adolescent idiopathic structural scoliosis (AIS) is the most common spinal deformity in children. Specific physiotherapeutic exercises are recommended as the first step in the treatment of idiopathic scoliosis. The Schroth method is most often used and consists out of auto-correction in three dimensions, breathing exercises, education and home exercises. Aim: Examination of the efficacy of short-term controlled Schroth exercises in the treatment of adolescents with AIS. Material and methods: A prospective clinically controlled study comprised 23 adolescent patients who were previously treated with "usual" physiotherapy, but without significant success. The initial evaluation included physical examination, anthropometric measurements, scoliometry and spinal radiography. The children were assigned 60 min long individual therapy sessions. All the children had 15 sessions (3 per week, during 5 weeks) in the ambulatory settings, followed by a 30-45 min long daily home exercise program. Angle of trunk rotation (ATR), trunk lateral flexion and respiratory index were analyzed before and after the study. Results: Eighteen children, 16 girls and 2 boys, mean age 13.38 ± 2.17 years, completed the study. Baseline mean Cobb angle of the largest curve was 28°. 61.1% of the children wore a brace. After treatment, ATR was significantly reduced at Th8-12 and L1-5 level, while lateral flexion and respiratory index increased significantly. Conclusion: The Schroth method improved posture and esthetic appearance, as well as breathing and flexibility of the spine in children with AIS.
Keywords	idiopathic scoliosis ; physiotherapeutic exercises ; schroth method ; Medicine ; R
Subject code	796
Language	English
Publishing date	2020-01-01T00:00:00Z
Publisher	University of Belgrade, Medical Faculty
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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