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Article ; Online: Measuring Lung Volumes in an Office With a New Device Body-Box Free.

Pérez-Padilla, Rogelio / Gochicoa-Rangel, Laura / Thirión-Romero, Ireri

2021 Volume 159, Issue 6, Page(s) 2143–2144

MeSH term(s)	Humans ; Lung Volume Measurements ; Plethysmography
Language	English
Publishing date	2021-05-25
Publishing country	United States
Document type	Editorial ; Comment
ZDB-ID	1032552-9
ISSN	1931-3543 ; 0012-3692
ISSN (online)	1931-3543
ISSN	0012-3692
DOI	10.1016/j.chest.2021.02.042
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Article ; Online: ALAT 2023 Recommendations for Performing Respiratory Function Studies.

Schönffeldt-Guerrero, Patricia / Gochicoa-Rangel, Laura / Aguirre Franco, Carlos / Arce, Santiago C / Rodríguez Flores, Cecilia

Archivos de bronconeumologia

2023 Volume 59, Issue 10, Page(s) 619–620

MeSH term(s)	Humans ; Respiratory Physiological Phenomena
Language	Spanish
Publishing date	2023-04-28
Publishing country	Spain
Document type	Editorial
ZDB-ID	733126-5
ISSN	1579-2129 ; 0300-2896
ISSN (online)	1579-2129
ISSN	0300-2896
DOI	10.1016/j.arbres.2023.04.004
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Article: Seguimiento de los pacientes después de neumonía por COVID-19. Secuelas pulmonares.

Chérrez-Ojeda, Iván / Gochicoa-Rangel, Laura / Salles-Rojas, Antonio / Mautong, Hans

Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993)

2021 Volume 67, Issue 4, Page(s) 350–369

Abstract: Coronavirus disease 2019 (COVID-19) is an infection caused by SARS-CoV-2 that has caused an unprecedented pandemic with a high rate of morbidity and mortality worldwide. Although most cases are mild, there are a considerable number of patients who ... ...

Title translation	Follow-up of patients after COVID-19 pneumonia. Pulmonary sequelae.
Abstract	Coronavirus disease 2019 (COVID-19) is an infection caused by SARS-CoV-2 that has caused an unprecedented pandemic with a high rate of morbidity and mortality worldwide. Although most cases are mild, there are a considerable number of patients who develop pneumonia or even acute respiratory distress syndrome (ARDS). After having recovered from the initial disease, many patients continue with various symptoms (fatigue, dry cough, fever, dyspnea, anosmia, and chest pain, among others.), which has led to consider the possible existence of "post-COVID-19 syndrome". Although the definition and validity of this syndrome are not clear yet, several studies report that individuals who have recovered from COVID-19 may have persistent symptoms, radiological abnormalities, and compromised respiratory function. Current evidence suggests that there is a large number of pulmonary sequelae after COVID-19 pneumonia (interstitial thickening, ground glass opacities, crazy paving pattern, and bronchiectasis, among others.). Likewise, it seems that pulmonary function tests (spirometry, DLCO, 6MWT, and measurement of maximum respiratory pressures), in addition to high-resolution computed axial tomographies (CAT scan), are useful for the assessment of these post-COVID-19 pulmonary sequelae. This review aims to describe the possible pulmonary sequelae after COVID-19 pneumonia, as well as to suggest diagnostic procedures for their correct assessment and follow-up; thus, allowing proper management by a multidisciplinary medical team.
MeSH term(s)	Bronchiectasis/diagnostic imaging ; Bronchiectasis/etiology ; Bronchiectasis/physiopathology ; COVID-19/complications ; Convalescence ; Disease Progression ; Follow-Up Studies ; Humans ; Hypoxia/blood ; Hypoxia/etiology ; Hypoxia/physiopathology ; Lung Diseases/diagnostic imaging ; Lung Diseases/etiology ; Lung Diseases, Interstitial/diagnostic imaging ; Lung Diseases, Interstitial/etiology ; Lung Diseases, Interstitial/physiopathology ; Mental Disorders/etiology ; Mental Disorders/physiopathology ; Oxygen/blood ; Pulmonary Embolism/diagnostic imaging ; Pulmonary Embolism/etiology ; Pulmonary Embolism/physiopathology ; Respiratory Distress Syndrome/etiology ; Respiratory Distress Syndrome/physiopathology ; Respiratory Function Tests ; Spirometry ; Tomography, X-Ray Computed
Chemical Substances	Oxygen (S88TT14065)
Language	Spanish
Publishing date	2021-02-26
Publishing country	Mexico
Document type	Journal Article ; Review
ZDB-ID	639125-4
ISSN	0002-5151
ISSN	0002-5151
DOI	10.29262/ram.v67i4.847
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Article ; Online: Implementation of an Integrated Total Quality Management System in a Pulmonary Function Laboratory.

Sánchez-Jerónimo, Patricia / Silva-Cerón, Mónica / López-López, Miriam / Hernández-Morales, Víctor / Gochicoa-Rangel, Laura

Quality management in health care

2022 Volume 31, Issue 2, Page(s) 74–79

Abstract: Background and objectives: A worldwide objective in the area of health is to offer high-quality services supported by certification strategies that contribute to improving standards for processes commonly used in medicine. However, few pulmonary ... ...

Abstract	Background and objectives: A worldwide objective in the area of health is to offer high-quality services supported by certification strategies that contribute to improving standards for processes commonly used in medicine. However, few pulmonary function test laboratories (PFTLs) follow official standards in their daily operations or are organized around an integrated total quality management system (ITQMS) focused on their established processes. The aim was to determine the feasibility of implementing an ITQMS to accredit the International Organization for Standardization (ISO) 9001:2015 standard in a high-demand PFTL where 13 respiratory function tests are routinely performed together with teaching and research activities. Methods: This project was conducted at the PFTL of the Instituto Nacional de Enfermedades Respiratorias in Mexico City from November 2014 to August 2017 and involved the implementation of an ITQMS guided by ISO 9001:2015 in 5 phases: (1) the establishment of a work team; (2) the elaboration of situational diagnoses; (3) the development of guidelines for the ITQMS; (4) the implementation of the ITQMS model; and (5) the evaluation of the ITQMS. Results: Upon completing the 5 phases, an evaluation of the system by an internal audit identified 3 minor cases of nonconformity (NC), while additional observations and an external audit found 5 minor cases of NC. These issues were addressed through a root-cause analysis to establish an action plan for each one. At the end of the process, the institution was granted the ISO 9001:2015 certification for its 3 processes: medical attention in support of diagnoses, teaching, and research. Conclusions: It is possible to implement an ISO quality management system as a routine operating methodology in a high-demand PFTL.
MeSH term(s)	Humans ; Laboratories ; Total Quality Management
Language	English
Publishing date	2022-06-01
Publishing country	United States
Document type	Journal Article
ZDB-ID	1162319-6
ISSN	1550-5154 ; 1063-8628
ISSN (online)	1550-5154
ISSN	1063-8628
DOI	10.1097/QMH.0000000000000333
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Article: Challenges in the Management of Post-COVID-19 Pulmonary Fibrosis for the Latin American Population.

Cherrez-Ojeda, Ivan / Cortés-Telles, Arturo / Gochicoa-Rangel, Laura / Camacho-Leon, Génesis / Mautong, Hans / Robles-Velasco, Karla / Faytong-Haro, Marco

Journal of personalized medicine

2022 Volume 12, Issue 9

Abstract: This commentary aims to highlight some of the major issues (with possible solutions) that the Latin American region is currently dealing with in managing post-COVID-19 pulmonary fibrosis. Overall, there is little evidence for successful long-term COVID- ... ...

Abstract	This commentary aims to highlight some of the major issues (with possible solutions) that the Latin American region is currently dealing with in managing post-COVID-19 pulmonary fibrosis. Overall, there is little evidence for successful long-term COVID-19 follow-up treatment. The lack of knowledge regarding proper treatment is exacerbated in Latin America by a general lack of resources devoted to healthcare, and a lack of availability and access to multidisciplinary teams. The discussion suggests that better infrastructure (primarily multicenter cohorts of COVID-19 survivors) and well-designed studies are required to develop scientific knowledge to improve treatment for the increasing prevalence of pulmonary fibrosis in Latin America.
Language	English
Publishing date	2022-08-27
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662248-8
ISSN	2075-4426
ISSN	2075-4426
DOI	10.3390/jpm12091393
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Article ; Online: Small airway disease in post-acute COVID-19 syndrome, a non-conventional approach in three years follow-up of a patient with long COVID: a case report.

Cherrez-Ojeda, Ivan / Osorio, Maria F / Robles-Velasco, Karla / Calderón, Juan C / Cortés-Télles, Arturo / Zambrano, Jorge / Guarderas, Cristian / Intriago, Belen / Gochicoa-Rangel, Laura

Journal of medical case reports

2023 Volume 17, Issue 1, Page(s) 386

Abstract: Background: Small airways disease (SAD), a novel finding described in post-acute COVID-19 patients, should be suspected when respiratory symptoms continue, air trapping persists on expiratory CT scans, and imaging findings fail to improve despite ... ...

Abstract	Background: Small airways disease (SAD), a novel finding described in post-acute COVID-19 patients, should be suspected when respiratory symptoms continue, air trapping persists on expiratory CT scans, and imaging findings fail to improve despite objectively better conventional pulmonary function test (PFT) parameters. The forced oscillation technique (FOT) and Multiple breathing washout (MBW) are both very sensitive methods for detecting anomalies in the peripheral airways. Case presentation: We discuss the case of a 60-year-old Hispanic patient who had severe COVID-19 pneumonia and developed dyspnea, fatigue, and limited daily activity a year later. The PFTs revealed restrictive lung disease, as seen by significant diffusing capacity of the lungs for carbon monoxide (DLCO) decrease, severe desaturation, and poor 6-min walk test (6MWT) performance. The patient was treated with lowering corticosteroids as well as pulmonary rehabilitation (PR). During the 24-month follow-up, the dyspnea and fatigue persisted. On PFTs, 6MWT performance and restricted pattern improved slightly, but MBW discovered significant ventilatory inhomogeneity. FOT revealed substantial peripheral airway obstructive abnormalities. On CT scans, air trapping and ground-glass opacities (GGO) improved somewhat. The patient used a bronchodilator twice a day and low-dose inhaled corticosteroids (160 µg of budesonide and 4.5 µg of formoterol fumarate dihydrate) for nine months. PR sessions were resuming. The restricting parameters were stabilized and the DLCO had normalized after 36 months, with a 6MWT performance of 87% but significant desaturation. The CT scan revealed traction bronchiectasis, low GGO, and persistent air trapping. Without normalization, FOT and MBW scores improved, indicating small airway disease. Conclusions: The necessity of integrating these tests when detecting SAD is emphasized in our paper. This article lays the foundation for future research into the best ways to manage and monitor SAD in post-acute COVID-19 patients.
MeSH term(s)	Humans ; Middle Aged ; Post-Acute COVID-19 Syndrome ; Follow-Up Studies ; COVID-19 ; Asthma ; Dyspnea/etiology ; Fatigue
Language	English
Publishing date	2023-09-11
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2269805-X
ISSN	1752-1947 ; 1752-1947
ISSN (online)	1752-1947
ISSN	1752-1947
DOI	10.1186/s13256-023-04113-7
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Article: Dynapenia and Sarcopenia in Post-COVID-19 Syndrome Hospitalized Patients Are Associated with Severe Reduction in Pulmonary Function.

Orea-Tejeda, Arturo / Robles-Hernández, Robinson / González-Islas, Dulce / Jimenez-Gallardo, Luz / Gochicoa-Rangel, Laura / Castorena-Maldonado, Armando / Hernández-Zenteno, Rafael / Montañez-Orozco, Alvaro / Valderrábano-Salas, Benigno

Journal of clinical medicine

2023 Volume 12, Issue 20

Abstract: Background: After hospital discharge, post-COVID-19 syndrome has been observed to be associated with impaired diffusing capacity, respiratory muscle strength, and lung imaging abnormalities, in addition to loss of muscle mass/strength, sarcopenia, and ... ...

Abstract	Background: After hospital discharge, post-COVID-19 syndrome has been observed to be associated with impaired diffusing capacity, respiratory muscle strength, and lung imaging abnormalities, in addition to loss of muscle mass/strength, sarcopenia, and obesity impact exercise tolerance, pulmonary functions, and overall prognosis. However, the relationship between lung function and the coexistence of obesity with low muscle strength and sarcopenia in post-COVID-19 patients remains poorly investigated. Therefore, our aim was to evaluate the association between lung function and the coexistence of obesity with dynapenia and sarcopenia in post-COVID-19 syndrome patients. Methods: This cross-sectional study included subjects who were hospitalized due to moderate to severe COVID-19, as confirmed by PCR testing. Subjects who could not be contacted, declined to participate, or died before the follow-up visit were excluded. Results: A total of 711 subjects were evaluated; the mean age was 53.64 ± 13.57 years, 12.4% had normal weight, 12.6% were dynapenic without obesity, 8.3% had sarcopenia, 41.6% had obesity, 21.2% had dynapenic obesity, and 3.8% had sarcopenic obesity. In terms of pulmonary function, the dynapenic subjects showed decreases of -3.45% in FEV Conclusions: In post-COVID-19 syndrome, dynapenia and sarcopenia-both with and without obesity-have been associated with lower lung function.
Language	English
Publishing date	2023-10-11
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2662592-1
ISSN	2077-0383
ISSN	2077-0383
DOI	10.3390/jcm12206466
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Article ; Online: Reply to: The Race Arithmetic of the Global Lung Function Initiative Global Reference Equations.

Bowerman, Cole / Bhakta, Nirav R / Brazzale, Danny / Cooper, Brendan G / Cooper, Julie / Gochicoa-Rangel, Laura / Haynes, Jeffrey / Kaminsky, David A / Lan, Le Thi Tuyet / Masekela, Refiloe / McCormack, Meredith C / Steenbruggen, Irene / Stanojevic, Sanja

American journal of respiratory and critical care medicine

2023 Volume 209, Issue 1, Page(s) 114–115

MeSH term(s)	Humans ; Lung ; Spirometry ; Reference Values ; Vital Capacity ; Forced Expiratory Volume
Language	English
Publishing date	2023-05-16
Publishing country	United States
Document type	Letter
ZDB-ID	1180953-x
ISSN	1535-4970 ; 0003-0805 ; 1073-449X
ISSN (online)	1535-4970
ISSN	0003-0805 ; 1073-449X
DOI	10.1164/rccm.202304-0729LE
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Article: Arterial Blood Gases in Normal Subjects at 2240 Meters Above Sea Level: Impact of Age, Gender, and Body Mass Index.

Cid-Juárez, Silvia / Téllez-Navarrete, Norma A / Bautista-Bernal, Anaid / León-Gómez, Pablo / Salas-Escamilla, Isabel / Gochicoa-Rangel, Laura / Pérez-Padilla, Rogelio

Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion

2023 Volume 75, Issue 1, Page(s) 29–36

Abstract: Background: The values of arterial blood gases (ABG) change with altitude above sea level; empirical verification is essential because ventilatory acclimatization varies with ethnicity and a population's adaptation.: Objective: The aim of the study ... ...

Abstract	Background: The values of arterial blood gases (ABG) change with altitude above sea level; empirical verification is essential because ventilatory acclimatization varies with ethnicity and a population's adaptation. Objective: The aim of the study was to describe ABG in a healthy population residing at 2,240 meters above sea level, to identify the mean level of alveolar ventilation (PaCO Methods: We conducted a cross-sectional study in a referral center for respiratory diseases in Mexico City. Associations among variables with correlation coefficient and regression models of PaO Results: Two hundred and seventeen healthy subjects were evaluated with a mean age of 40 ± 15 years, mean of the PaO Conclusion: Mean PaCO
MeSH term(s)	Humans ; Female ; Adult ; Middle Aged ; Body Mass Index ; Cross-Sectional Studies ; Aging ; Altitude ; Gases
Chemical Substances	Gases
Language	English
Publishing date	2023-02-28
Publishing country	Mexico
Document type	Journal Article
ZDB-ID	138348-6
ISSN	0034-8376
ISSN	0034-8376
DOI	10.24875/RIC.22000281
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Article ; Online: Lung function is related to salivary cytokines and hormones in healthy children. An exploratory cross-sectional study.

Gochicoa-Rangel, Laura / Chávez, Jaime / Del-Río-Hidalgo, Rodrigo / Guerrero-Zúñiga, Selene / Mora-Romero, Uri / Benítez-Pérez, Rosaura / Rodríguez-Moreno, Luis / Torre-Bouscoulet, Luis / Vargas, Mario H

Physiological reports

2023 Volume 11, Issue 23, Page(s) e15861

Abstract: Pulmonary mechanics has been traditionally viewed as determined by lung size and physical factors such as frictional forces and tissue viscoelastic properties, but few information exists regarding potential influences of cytokines and hormones on lung ... ...

Abstract	Pulmonary mechanics has been traditionally viewed as determined by lung size and physical factors such as frictional forces and tissue viscoelastic properties, but few information exists regarding potential influences of cytokines and hormones on lung function. Concentrations of 28 cytokines and hormones were measured in saliva from clinically healthy scholar children, purposely selected to include a wide range of body mass index (BMI). Lung function was assessed by impulse oscillometry, spirometry, and diffusing capacity for carbon monoxide, and expressed as z-score or percent predicted. Ninety-six scholar children (55.2% female) were enrolled. Bivariate analysis showed that almost all lung function variables correlated with one or more cytokine or hormone, mainly in boys, but only some of them remained statistically significant in the multiple regression analyses. Thus, after adjusting by height, age, and BMI, salivary concentrations of granulocyte-macrophage colony-stimulating factor (GM-CSF) in boys were associated with zR5-R20 and reactance parameters (zX20, zFres, and zAX), while glucagon inversely correlated with resistances (zR5 and zR20). Thus, in physiological conditions, part of the mechanics of breathing might be influenced by some cytokines and hormones, including glucagon and GM-CSF. This endogenous influence is a novel concept that warrants in-depth characterization.
MeSH term(s)	Male ; Child ; Humans ; Female ; Cytokines ; Granulocyte-Macrophage Colony-Stimulating Factor ; Cross-Sectional Studies ; Glucagon ; Lung
Chemical Substances	Cytokines ; Granulocyte-Macrophage Colony-Stimulating Factor (83869-56-1) ; Glucagon (9007-92-5)
Language	English
Publishing date	2023-12-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	2724325-4
ISSN	2051-817X ; 2051-817X
ISSN (online)	2051-817X
ISSN	2051-817X
DOI	10.14814/phy2.15861
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