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  1. Article ; Online: Boosting Dose of Pfizer-BioNtech mRNA Vaccine Against SARS-CoV-2 Does Not Affect Reproductive Outcomes in In-Vitro Fertilization Patients: A Cohort Study.

    Adler Lazarovits, Chana / Smadja, Adama / Kabessa, Maor / Allouche Kam, Hadas / Nevo, Lea / Godin, Miri / Bentov, Yaakov / Beharier, Ofer / Esh Broder, Efrat / Holzer, Hananel / Hershko Klement, Anat

    Journal of women's health (2002)

    2022  Volume 32, Issue 1, Page(s) 24–28

    Abstract: Background: ...

    Abstract Background:
    MeSH term(s) Male ; Female ; Pregnancy ; Humans ; Cohort Studies ; SARS-CoV-2 ; COVID-19 Vaccines ; COVID-19/prevention & control ; Semen ; Fertilization in Vitro ; Fertilization ; mRNA Vaccines
    Chemical Substances COVID-19 Vaccines
    Language English
    Publishing date 2022-11-22
    Publishing country United States
    Document type Observational Study ; Journal Article
    ZDB-ID 1139774-3
    ISSN 1931-843X ; 1059-7115 ; 1540-9996
    ISSN (online) 1931-843X
    ISSN 1059-7115 ; 1540-9996
    DOI 10.1089/jwh.2022.0163
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Ovarian follicular function is not altered by SARS-Cov-2 infection or BNT162b2 mRNA Covid-19 vaccination.

    Bentov, Yaakov / Beharier, Ofer / Moav-Zafrir, Arbel / Kabessa, Maor / Godin, Miri / Greenfield, Caryn / Ketzinel-Gilad, Mali / Esh Broder, Efrat / Holzer, Hananel / Wolf, Dana / Oiknine-Djian, Esther / Barghouti, Iyad / Goldman-Wohl, Debra / Yagel, Simcha / Walfisch, Asnat / Hershko Klement, Anat

    medRxiv

    Abstract: Importance: This is the first study to examine the impact of SARS-Cov-2 infection and COVID-19 vaccination on ovarian function. Objective: To characterize anti-COVID-19 antibodies in follicular fluid and compare ovarian follicle function in women ... ...

    Abstract Importance: This is the first study to examine the impact of SARS-Cov-2 infection and COVID-19 vaccination on ovarian function. Objective: To characterize anti-COVID-19 antibodies in follicular fluid and compare ovarian follicle function in women following confirmed SARS-CoV-2 infection, COVID-19 vaccination, and non-infected, unvaccinated controls. Design: This is a cohort study conducted between February 1 and March 10, 2021. Setting: A single university hospital-based IVF clinic. Participants: Consecutive sample of female patients undergoing oocyte retrieval. Interventions: Consenting patients were recruited and assigned to one of three study groups: recovering from confirmed COVID 19 (n=9); vaccinated (n=9); and uninfected, non-vaccinated controls (n=14). Serum and follicular fluid samples were taken and analyzed for anti-COVID IgG as well as estrogen, progesterone and HSPG2 concentration, as well as the number and maturity of aspirated oocytes and previous estrogen and progesterone measurements. Main outcome measures: Follicular function, including steroidogenesis, follicular response to the LH/hCG trigger, and oocyte quality biomarkers. Results: Both natural and vaccine elicited anti-COVID IgG antibodies were detected in the follicular fluid in levels proportional to the IgG serum concentration. No differences were detected in any of the surrogate ovarian follicle quality reporting parameters. Conclusions and relevance: Both SARS-COV-2 infection and vaccination with the BNT162b2 mRNA vaccine mediate IgG immunity that crosses into the follicular fluid. No detrimental effect on follicular function was detected.
    Keywords covid19
    Language English
    Publishing date 2021-04-13
    Publisher Cold Spring Harbor Laboratory Press
    Document type Article ; Online
    DOI 10.1101/2021.04.09.21255195
    Database COVID19

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  3. Article ; Online: Acute renal failure may lead to reversible azoospermia.

    Eldar, Ido / Godin, Miri / Bdolah, Yuval / Hurwitz, Arye / Haimov-Kochman, Ronit

    Fertility and sterility

    2008  Volume 90, Issue 5, Page(s) 2007.e11–2

    Abstract: Objective: To report a possible association between azoospermia and acute renal failure.: Design: A case report.: Setting: An in vitro fertilization unit in an academic medical center.: Patient(s): A patient with high-gonadotropin azoospermia ... ...

    Abstract Objective: To report a possible association between azoospermia and acute renal failure.
    Design: A case report.
    Setting: An in vitro fertilization unit in an academic medical center.
    Patient(s): A patient with high-gonadotropin azoospermia and a history of acute obstructive renal failure because of bilateral renal calculi, who was referred for testicular sperm extraction.
    Intervention(s): Deferral of the surgical procedure.
    Main outcome measure(s): Return of sperm into the patient's ejaculate.
    Result(s): Four months after normalization of his renal function tests, the sperm analysis showed reversal of the azoospermic state.
    Conclusion(s): Azoospermic patients with recent history of acute renal failure would be followed up for several months after renal function normalization, awaiting reappearance of sperm in the ejaculate.
    MeSH term(s) Acute Kidney Injury/complications ; Azoospermia/etiology ; Azoospermia/physiopathology ; Humans ; Male ; Middle Aged ; Remission, Spontaneous ; Sperm Count ; Sperm Motility ; Spermatogenesis
    Language English
    Publishing date 2008-11
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 80133-1
    ISSN 1556-5653 ; 0015-0282
    ISSN (online) 1556-5653
    ISSN 0015-0282
    DOI 10.1016/j.fertnstert.2007.12.052
    Database MEDical Literature Analysis and Retrieval System OnLINE

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