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  1. Article ; Online: Bleeder With a Clot: Thrombosis Following Treatment of Bleeding in a Child With Severe Hemophilia B.

    Goh, Mei Ching / Lam, Joyce Ching Mei / Tan, Ah Moy / Bhattacharyya, Rajat

    Journal of pediatric hematology/oncology

    2020  Volume 43, Issue 4, Page(s) e561–e563

    Abstract: A 16-year-old boy with severe hemophilia B and minimal bleeding manifestations in his early childhood presented with gastrointestinal bleeding at 11 years of age. Following administration of prothrombin complex concentrate, he developed peripheral venous ...

    Abstract A 16-year-old boy with severe hemophilia B and minimal bleeding manifestations in his early childhood presented with gastrointestinal bleeding at 11 years of age. Following administration of prothrombin complex concentrate, he developed peripheral venous thrombosis and cerebral sinovenous thrombosis, posing a management dilemma. His cerebral sinovenous thrombosis resolved spontaneously, proving watchful waiting to be a useful strategy. He developed spontaneous intracranial bleed at 14 years of age for which he was treated with factor IX concentrate and commenced on prophylaxis. We discuss the factors contributing to genotype-phenotype dissonance in severe hemophilia and considerations before commencing prophylaxis in such cases.
    MeSH term(s) Adolescent ; Blood Coagulation Factors/adverse effects ; Blood Coagulation Factors/therapeutic use ; Factor IX/therapeutic use ; Hemophilia B/therapy ; Hemorrhage/therapy ; Humans ; Male ; Thrombosis/etiology
    Chemical Substances Blood Coagulation Factors ; prothrombin complex concentrates (37224-63-8) ; Factor IX (9001-28-9)
    Language English
    Publishing date 2020-07-10
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 1231152-2
    ISSN 1536-3678 ; 1077-4114 ; 0192-8562
    ISSN (online) 1536-3678
    ISSN 1077-4114 ; 0192-8562
    DOI 10.1097/MPH.0000000000001904
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1537: Show issues Location:
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  2. Article: Five-Year Review of Patients Presenting with Non-Accidental Injury to a Children's Emergency Unit in Singapore.

    Chew, Yi Rong / Cheng, Michaela Hl / Goh, Mei Ching / Shen, Liang / Wong, Peter Cy / Ganapathy, Sashikumar

    Annals of the Academy of Medicine, Singapore

    2018  Volume 47, Issue 10, Page(s) 413–419

    Abstract: Introduction: There is an increasing trend of physical child abuse cases reported in Singapore. Children presenting to the Emergency Department with injuries require a high index of suspicion for clinicians to distinguish those that are abusive in ... ...

    Abstract Introduction: There is an increasing trend of physical child abuse cases reported in Singapore. Children presenting to the Emergency Department with injuries require a high index of suspicion for clinicians to distinguish those that are abusive in nature.
    Materials and methods: A retrospective study of children with diagnosis of NAI presenting to KK Women's and Children's Hospital (KKH) from June 2011 to May 2016 was conducted.
    Results: There were 1917 cases reported from 1730 subjects, of  which: 8.8% of subjects had repeat visits; 55.2% of cases were male; and mean age was 7.69 years. Racial demographics were: Chinese 45.5%, Malay 33.4%, Indian 15.4% and Others 5.9%. The most frequent injuries sustained were head and neck (50.8%), limbs (32.2%), and chest (5.7%). Of the type of injuries, 55% had contusions, 21% had cane marks, 16% had lacerations, 4.4% had burn marks and 1% sustained fractures. Males were more likely to be caned (
    Conclusion: Analysing these factors provide a better understanding of  the presentation of  NAI cases, including 'red flags' and vulnerable groups who should have better protection.
    MeSH term(s) Age Factors ; Child ; Child Abuse/prevention & control ; Child Abuse/statistics & numerical data ; Child, Preschool ; Cohort Studies ; Emergency Service, Hospital/statistics & numerical data ; Ethnic Groups/statistics & numerical data ; Female ; Hospitalization/statistics & numerical data ; Humans ; Injury Severity Score ; Male ; Mandatory Reporting ; Needs Assessment ; Physical Abuse/prevention & control ; Physical Abuse/statistics & numerical data ; Prevalence ; Retrospective Studies ; Risk Assessment ; Sex Factors ; Singapore ; Vulnerable Populations/statistics & numerical data ; Wounds and Injuries/diagnosis ; Wounds and Injuries/epidemiology
    Language English
    Publishing date 2018-11-20
    Publishing country Singapore
    Document type Journal Article
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2420: Show issues Location:
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  3. Article: Severe vitamin B12 deficiency in a 7-month-old boy.

    Tan, Michelle L N / Goh, Mei Ching / Fu, Kristy X H / Aw, Marion H Y / Quak, Seng Hock / Goh, Denise L M

    Annals of the Academy of Medicine, Singapore

    2015  Volume 44, Issue 3, Page(s) 109–111

    MeSH term(s) Humans ; Infant ; Male ; Severity of Illness Index ; Vitamin B 12 Deficiency/complications ; Vitamin B 12 Deficiency/diagnosis
    Language English
    Publishing date 2015-03-14
    Publishing country Singapore
    Document type Case Reports ; Letter
    ZDB-ID 604527-3
    ISSN 0304-4602
    ISSN 0304-4602
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2420: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)

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