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  1. Book: The new executive brain

    Goldberg, Elkhonon

    frontal lobes in a complex world

    2009  

    Author's details Elkhonon Goldberg
    Keywords Frontal Lobe / physiology ; Brain Diseases / physiopathology ; Mental Processes / physiology ; Frontal lobes ; Neuropsychology ; Frontal lobes--Physiology ; Brain--Diseases--Pathophysiology
    Subject code 612.825
    Language English
    Size XV, 334 S. : Ill., 24 cm
    Publisher Oxford Univ. Press
    Publishing place Oxford u.a.
    Publishing country Great Britain
    Document type Book
    Note Includes bibliographical references and index
    HBZ-ID HT016161287
    ISBN 978-0-19-532940-7 ; 0-19-532940-6
    Database Catalogue ZB MED Medicine, Health

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  2. Article ; Online: Commentary on "Consciousness in a multilevel architecture: Evidence from the right side of the brain" by B.M. Velichkovsky et al.

    Goldberg, Elkhonon

    Consciousness and cognition

    2019  Volume 73, Page(s) 102753

    MeSH term(s) Brain ; Consciousness ; Humans
    Language English
    Publishing date 2019-05-30
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 1106647-7
    ISSN 1090-2376 ; 1053-8100
    ISSN (online) 1090-2376
    ISSN 1053-8100
    DOI 10.1016/j.concog.2019.05.001
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Large-scale distributed networks and cerebral hemispheres.

    Goldberg, Elkhonon / Tulviste, Jaan

    Cortex; a journal devoted to the study of the nervous system and behavior

    2022  Volume 152, Page(s) 53–58

    Abstract: The two main large-scale distributed networks, Central Executive (CEN) and Default Mode (DMN) have been extensively studied, but their relationship to hemispheric specialization has not been comprehensively addressed. We present evidence that they are ... ...

    Abstract The two main large-scale distributed networks, Central Executive (CEN) and Default Mode (DMN) have been extensively studied, but their relationship to hemispheric specialization has not been comprehensively addressed. We present evidence that they are neuroanatomically asymmetric: the CEN components are volumetrically larger in the right hemisphere, and DMN components are volumetrically larger in the left hemisphere. Based on this, the possibility that CEN and DMN are also functionally asymmetric is introduced and implications of the putative functional asymmetry of large-scale distributed networks for refining our understanding of hemispheric specialization are examined.
    MeSH term(s) Brain ; Cerebrum ; Humans ; Magnetic Resonance Imaging ; Nerve Net
    Language English
    Publishing date 2022-04-05
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 280622-8
    ISSN 1973-8102 ; 0010-9452
    ISSN (online) 1973-8102
    ISSN 0010-9452
    DOI 10.1016/j.cortex.2022.03.010
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Book: Die Regie im Gehirn

    Goldberg, Elkhonon

    wo wir Pläne schmieden und Entscheidungen treffen

    2002  

    Title translation The executive brain
    Author's details Elkhonon Goldberg. Vorw. von Oliver Sacks. [Übers.: Andrea Viala]
    Keywords Frontal Lobe / physiopathology ; Brain Damage, Chronic / physiopathology ; Mental Processes / physiology ; Stirnhirn ; Hirnfunktion
    Subject Gehirn ; Hirnleistung ; Hirnaktivität ; Hirnphysiologie ; Gehirnphysiologie ; Gehirnaktivität ; Gehirnfunktion ; Frontalhirn ; Lobus frontalis cerebri ; Stirnlappen ; Frontallappen ; Scheitellappen
    Language German
    Size 340 S. : Ill., 22 cm
    Publisher VAK-Verl.-GmbH
    Publishing place Kirchzarten bei Freiburg
    Publishing country Germany
    Document type Book
    Note Aus dem Engl. übers.
    HBZ-ID HT013315057
    ISBN 3-935767-04-8 ; 978-3-935767-04-0
    Database Catalogue ZB MED Medicine, Health

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  5. Book: Creativity

    Goldberg, Elkhonon

    the human brain in the age of innovation

    2018  

    Author's details by Elkhonon Goldberg
    MeSH term(s) Brain/physiology ; Creativity
    Language English
    Size p. ;, cm.
    Document type Book
    ISBN 9780190466497 ; 0190466499
    Database Catalogue of the US National Library of Medicine (NLM)

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  6. Book ; Online: Deep learning in a bilateral brain with hemispheric specialization

    Rajagopalan, Chandramouli / Rawlinson, David / Goldberg, Elkhonon / Kowadlo, Gideon

    2022  

    Abstract: The brains of all bilaterally symmetric animals on Earth are divided into left and right hemispheres. The anatomy and functionality of the hemispheres have a large degree of overlap, but there are asymmetries and they specialize to possess different ... ...

    Abstract The brains of all bilaterally symmetric animals on Earth are divided into left and right hemispheres. The anatomy and functionality of the hemispheres have a large degree of overlap, but there are asymmetries and they specialize to possess different attributes. Several studies have used computational models to mimic hemispheric asymmetries with a focus on reproducing human data on semantic and visual processing tasks. In this study, we aimed to understand how dual hemispheres could interact in a given task. We propose a bilateral artificial neural network that imitates a lateralization observed in nature: that the left hemisphere specializes in specificity and the right in generalities. We used two ResNet-9 convolutional neural networks with different training objectives and tested it on an image classification task. Our analysis found that the hemispheres represent complementary features that are exploited by a network head which implements a type of weighted attention. The bilateral architecture outperformed a range of baselines of similar representational capacity that don't exploit differential specialization. The results demonstrate the efficacy of bilateralism, contribute to an understanding of bilateralism in biological brains and the architecture serves as an inductive bias when designing new AI systems.

    Comment: 14 pages, 11 figures
    Keywords Quantitative Biology - Neurons and Cognition ; Computer Science - Artificial Intelligence ; Computer Science - Machine Learning ; Computer Science - Neural and Evolutionary Computing ; I.2.6 ; I.5.0 ; I.5.1
    Subject code 501 ; 006
    Publishing date 2022-09-08
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Multiple Neuroinvasive Pathways in COVID-19.

    Bougakov, Dmitri / Podell, Kenneth / Goldberg, Elkhonon

    Molecular neurobiology

    2020  Volume 58, Issue 2, Page(s) 564–575

    Abstract: COVID-19 is a highly infectious viral disease caused by the novel coronavirus SARS-CoV-2. While it was initially regarded as a strictly respiratory illness, the impact of COVID-19 on multiple organs is increasingly recognized. The brain is among the ... ...

    Abstract COVID-19 is a highly infectious viral disease caused by the novel coronavirus SARS-CoV-2. While it was initially regarded as a strictly respiratory illness, the impact of COVID-19 on multiple organs is increasingly recognized. The brain is among the targets of COVID-19, and it can be impacted in multiple ways, both directly and indirectly. Direct brain infection by SARS-CoV-2 may occur via axonal transport via the olfactory nerve, eventually infecting the olfactory cortex and other structures in the temporal lobe, and potentially the brain stem. A hematogenous route, which involves viral crossing of blood-brain barrier, is also possible. Secondary mechanisms involve hypoxia due to respiratory failure, as well as aberrant immune response leading to various forms of encephalopathy, white matter damage, and abnormal blood clotting resulting in stroke. Multiple neurological symptoms of COVID-19 have been described. These involve anosmia/ageusia, headaches, seizures, mental confusion and delirium, and coma. There is a growing concern that in a number of patients, long-term or perhaps even permanent cognitive impairment will persist well after the recovery from acute illness. Furthermore, COVID-19 survivors may be at increased risk for developing neurodegenerative diseases years or decades later. Since COVID-19 is a new disease, it will take months or even years to characterize the exact nature, scope, and temporal extent of its long-term neurocognitive sequelae. To that end, rigorous and systematic longitudinal follow-up will be required. For this effort to succeed, appropriate protocols and patient registries should be developed and put in place without delay now.
    MeSH term(s) Anosmia/virology ; Blood-Brain Barrier/virology ; Brain/virology ; COVID-19/complications ; Coma/virology ; Delirium/virology ; Headache/virology ; Humans ; Seizures/virology
    Keywords covid19
    Language English
    Publishing date 2020-09-29
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 645020-9
    ISSN 1559-1182 ; 0893-7648
    ISSN (online) 1559-1182
    ISSN 0893-7648
    DOI 10.1007/s12035-020-02152-5
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: The brain after COVID-19: Compensatory neurogenesis or persistent neuroinflammation?

    Goldberg, Elkhonon / Podell, Kenneth / Sodickson, Daniel K / Fieremans, Els

    EClinicalMedicine

    2020  Volume 31, Page(s) 100684

    Language English
    Publishing date 2020-12-24
    Publishing country England
    Document type Journal Article
    ISSN 2589-5370
    ISSN (online) 2589-5370
    DOI 10.1016/j.eclinm.2020.100684
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Multiple Neuroinvasive Pathways in COVID-19

    Bougakov, Dmitri / Podell, Kenneth / Goldberg, Elkhonon

    Mol. Neurobiol

    Abstract: COVID-19 is a highly infectious viral disease caused by the novel coronavirus SARS-CoV-2. While it was initially regarded as a strictly respiratory illness, the impact of COVID-19 on multiple organs is increasingly recognized. The brain is among the ... ...

    Abstract COVID-19 is a highly infectious viral disease caused by the novel coronavirus SARS-CoV-2. While it was initially regarded as a strictly respiratory illness, the impact of COVID-19 on multiple organs is increasingly recognized. The brain is among the targets of COVID-19, and it can be impacted in multiple ways, both directly and indirectly. Direct brain infection by SARS-CoV-2 may occur via axonal transport via the olfactory nerve, eventually infecting the olfactory cortex and other structures in the temporal lobe, and potentially the brain stem. A hematogenous route, which involves viral crossing of blood-brain barrier, is also possible. Secondary mechanisms involve hypoxia due to respiratory failure, as well as aberrant immune response leading to various forms of encephalopathy, white matter damage, and abnormal blood clotting resulting in stroke. Multiple neurological symptoms of COVID-19 have been described. These involve anosmia/ageusia, headaches, seizures, mental confusion and delirium, and coma. There is a growing concern that in a number of patients, long-term or perhaps even permanent cognitive impairment will persist well after the recovery from acute illness. Furthermore, COVID-19 survivors may be at increased risk for developing neurodegenerative diseases years or decades later. Since COVID-19 is a new disease, it will take months or even years to characterize the exact nature, scope, and temporal extent of its long-term neurocognitive sequelae. To that end, rigorous and systematic longitudinal follow-up will be required. For this effort to succeed, appropriate protocols and patient registries should be developed and put in place without delay now.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #808452
    Database COVID19

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  10. Article ; Online: Multiple Neuroinvasive Pathways in COVID-19

    Bougakov, Dmitri / Podell, Kenneth / Goldberg, Elkhonon

    Molecular Neurobiology ; ISSN 0893-7648 1559-1182

    2020  

    Keywords Cellular and Molecular Neuroscience ; covid19
    Language English
    Publisher Springer Science and Business Media LLC
    Publishing country us
    Document type Article ; Online
    DOI 10.1007/s12035-020-02152-5
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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